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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-107 Sentence denotes Angiotensin II activates the proinflammatory transcription factor nuclear factor-kappaB in human monocytes.
T2 108-191 Sentence denotes The renin-angiotensin system may contribute to the pathogenesis of atherosclerosis.
T3 192-277 Sentence denotes A common feature of all stages of atherosclerosis is inflammation of the vessel wall.
T4 278-402 Sentence denotes The transcription factor nuclear factor-kappaB (NF-kappaB) participates in most signaling pathways involved in inflammation.
T5 403-598 Sentence denotes This study therefore examined the effect of angiotensin (ANG) II on NF-kappaB activation in monocytic cells, a major cellular component of human atheroma, by electrophoretic mobility shift assay.
T6 599-744 Sentence denotes ANG II, like TNFalpha, caused rapid activation of NF-kappaB in human mononuclear cells isolated from peripheral blood by Ficoll density gradient.
T7 745-828 Sentence denotes This ANG II effect was blocked by the angiotensin AT1 receptor antagonist losartan.
T8 829-938 Sentence denotes Specificity of ANG II-induced NF-kappaB activation was ascertained by supershift and competition experiments.
T9 939-1057 Sentence denotes Moreover, ANG II stimulated NF-kappaB activation in human monocytes, but not in lymphocytes from the same preparation.
T10 1058-1187 Sentence denotes Together, the data demonstrate the ability of the vasoactive peptide ANG II to activate inflammatory pathways in human monocytes.
T1 0-107 Sentence denotes Angiotensin II activates the proinflammatory transcription factor nuclear factor-kappaB in human monocytes.
T2 108-191 Sentence denotes The renin-angiotensin system may contribute to the pathogenesis of atherosclerosis.
T3 192-277 Sentence denotes A common feature of all stages of atherosclerosis is inflammation of the vessel wall.
T4 278-402 Sentence denotes The transcription factor nuclear factor-kappaB (NF-kappaB) participates in most signaling pathways involved in inflammation.
T5 403-598 Sentence denotes This study therefore examined the effect of angiotensin (ANG) II on NF-kappaB activation in monocytic cells, a major cellular component of human atheroma, by electrophoretic mobility shift assay.
T6 599-744 Sentence denotes ANG II, like TNFalpha, caused rapid activation of NF-kappaB in human mononuclear cells isolated from peripheral blood by Ficoll density gradient.
T7 745-828 Sentence denotes This ANG II effect was blocked by the angiotensin AT1 receptor antagonist losartan.
T8 829-938 Sentence denotes Specificity of ANG II-induced NF-kappaB activation was ascertained by supershift and competition experiments.
T9 939-1057 Sentence denotes Moreover, ANG II stimulated NF-kappaB activation in human monocytes, but not in lymphocytes from the same preparation.
T10 1058-1187 Sentence denotes Together, the data demonstrate the ability of the vasoactive peptide ANG II to activate inflammatory pathways in human monocytes.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-14 protein denotes Angiotensin II
T2 29-65 protein denotes proinflammatory transcription factor
T3 66-87 protein denotes nuclear factor-kappaB
T4 91-106 cell_type denotes human monocytes
T5 112-117 protein denotes renin
T6 303-324 protein denotes nuclear factor-kappaB
T7 326-335 protein denotes NF-kappaB
T8 447-467 protein denotes angiotensin (ANG) II
T9 471-480 protein denotes NF-kappaB
T10 495-510 cell_type denotes monocytic cells
T11 599-605 protein denotes ANG II
T12 612-620 protein denotes TNFalpha
T13 649-658 protein denotes NF-kappaB
T14 662-685 cell_type denotes human mononuclear cells
T15 750-756 protein denotes ANG II
T16 844-850 protein denotes ANG II
T17 859-868 protein denotes NF-kappaB
T18 949-955 protein denotes ANG II
T19 967-976 protein denotes NF-kappaB
T20 991-1006 cell_type denotes human monocytes
T21 1019-1030 cell_type denotes lymphocytes
T22 1127-1133 protein denotes ANG II
T23 1171-1186 cell_type denotes human monocytes

semrep-sample

Id Subject Object Predicate Lexical cue
E1-ti-1 0-14 cui:C0003009 denotes Angiotensin II
E2-ti-1 45-65 cui:C0040648 denotes transcription factor
E3-ti-1 66-73 cui:C0521447 denotes nuclear
E4-ti-1 91-96 cui:C0020114 denotes human
E5-ti-1 97-106 cui:C0026473 denotes monocytes
T1 91-106 PART_OF denotes human monocytes
T2 88-90 LOCATION_OF denotes in
E1-ab-1 112-136 cui:C0035096 denotes renin-angiotensin system
E2-ab-1 159-171 cui:C0699748 denotes pathogenesis
E3-ab-1 175-190 cui:C0004153 denotes atherosclerosis
E1-ab-2 194-200 cui:C0205214 denotes common
E2-ab-2 226-241 cui:C0004153 denotes atherosclerosis
E3-ab-2 245-257 cui:C0021368 denotes inflammation
E4-ab-2 265-271 cui:C0005847 denotes vessel
E5-ab-2 272-276 cui:C0205380 denotes wall
E1-ab-3 282-302 cui:C0040648 denotes transcription factor
E2-ab-3 303-310 cui:C0521447 denotes nuclear
E3-ab-3 358-376 cui:C0037080 denotes signaling pathways
E4-ab-3 389-401 cui:C0021368 denotes inflammation
T3 377-385 AFFECTS denotes involved
E1-ab-4 408-413 cui:C0008972 denotes study
E2-ab-4 437-443 cui:C1280500 denotes effect
E3-ab-4 447-467 cui:C0003009 denotes angiotensin (ANG) II
E4-ab-4 471-480 cui:C0521447 denotes NF-kappaB
E5-ab-4 471-480 cui:C1521761 denotes NF-kappaB
E6-ab-4 495-504 cui:C0026473 denotes monocytic
E7-ab-4 505-510 cui:C0007634 denotes cells
E8-ab-4 514-519 cui:C0205164 denotes major
E9-ab-4 520-538 cui:C1166607 denotes cellular component
E10-ab-4 542-547 cui:C0020114 denotes human
E11-ab-4 548-556 cui:C0015697 denotes atheroma
E12-ab-4 561-597 cui:C0949632 denotes electrophoretic mobility shift assay
T4 471-480 AFFECTS denotes NF-kappaB
T5 542-556 PART_OF denotes human atheroma
E1-ab-5 599-605 cui:C0003009 denotes ANG II
E2-ab-5 629-634 cui:C0439831 denotes rapid
E3-ab-5 649-658 cui:C0521447 denotes NF-kappaB
E4-ab-5 649-658 cui:C1521761 denotes NF-kappaB
E5-ab-5 662-667 cui:C0020114 denotes human
E6-ab-5 668-685 cui:C0806987 denotes mononuclear cells
E7-ab-5 700-716 cui:C0229664 denotes peripheral blood
E8-ab-5 720-726 cui:C0016071 denotes Ficoll
E9-ab-5 727-734 cui:C0178587 denotes density
E10-ab-5 735-743 cui:C0439182 denotes gradient
T6 649-658 AFFECTS denotes NF-kappaB
T7 662-685 PART_OF denotes human mononuclear cells
E1-ab-6 750-756 cui:C0003009 denotes ANG II
E2-ab-6 757-763 cui:C1280500 denotes effect
E3-ab-6 795-798 cui:C0919524 denotes AT1
E4-ab-6 783-818 cui:C0815017 denotes angiotensin AT1 receptor antagonist
E5-ab-6 819-827 cui:C0126174 denotes losartan
T8 783-827 ISA denotes angiotensin AT1 receptor antagonist losartan
E1-ab-7 829-840 cui:C0037791 denotes Specificity
E2-ab-7 844-850 cui:C0003009 denotes ANG II
E3-ab-7 851-858 cui:C0205263 denotes induced
E4-ab-7 859-868 cui:C0521447 denotes NF-kappaB
E5-ab-7 859-868 cui:C1521761 denotes NF-kappaB
E6-ab-7 914-925 cui:C0679932 denotes competition
E7-ab-7 926-937 cui:C0681814 denotes experiments
E1-ab-8 949-955 cui:C0003009 denotes ANG II
E2-ab-8 967-976 cui:C0521447 denotes NF-kappaB
E3-ab-8 967-976 cui:C1521761 denotes NF-kappaB
E4-ab-8 991-996 cui:C0020114 denotes human
E5-ab-8 997-1006 cui:C0026473 denotes monocytes
E6-ab-8 1012-1015 cui:C1518422 denotes not
E7-ab-8 1019-1030 cui:C0024264 denotes lymphocytes
E8-ab-8 1040-1044 cui:C0445247 denotes same
E9-ab-8 1045-1056 cui:C1521827 denotes preparation
T9 991-1006 PART_OF denotes human monocytes
T10 988-990 LOCATION_OF denotes in
E1-ab-9 1072-1076 cui:C1511726 denotes data
E2-ab-9 1093-1100 cui:C0085732 denotes ability
E3-ab-9 1119-1126 cui:C0030956 denotes peptide
E4-ab-9 1127-1133 cui:C0003009 denotes ANG II
E5-ab-9 1146-1158 cui:C0333348 denotes inflammatory
E6-ab-9 1171-1176 cui:C0020114 denotes human
E7-ab-9 1177-1186 cui:C0026473 denotes monocytes
T11 1171-1186 PART_OF denotes human monocytes
T12 1168-1170 LOCATION_OF denotes in
R1 E5-ti-1 T1 subjectOf monocytes,human monocytes
R2 E4-ti-1 T1 objectOf human,human monocytes
R3 E5-ti-1 T2 subjectOf monocytes,in
R4 E1-ti-1 T2 objectOf Angiotensin II,in
R5 E3-ab-3 T3 subjectOf signaling pathways,involved
R6 E4-ab-3 T3 objectOf inflammation,involved
R7 E3-ab-4 T4 subjectOf angiotensin (ANG) II,NF-kappaB
R8 E7-ab-4 T4 objectOf cells,NF-kappaB
R9 E11-ab-4 T5 subjectOf atheroma,human atheroma
R10 E10-ab-4 T5 objectOf human,human atheroma
R11 E1-ab-5 T6 subjectOf ANG II,NF-kappaB
R12 E6-ab-5 T6 objectOf mononuclear cells,NF-kappaB
R13 E6-ab-5 T7 subjectOf mononuclear cells,human mononuclear cells
R14 E5-ab-5 T7 objectOf human,human mononuclear cells
R15 E5-ab-6 T8 subjectOf losartan,angiotensin AT1 receptor antagonist losartan
R16 E4-ab-6 T8 objectOf angiotensin AT1 receptor antagonist,angiotensin AT1 receptor antagonist losartan
R17 E5-ab-8 T9 subjectOf monocytes,human monocytes
R18 E4-ab-8 T9 objectOf human,human monocytes
R19 E5-ab-8 T10 subjectOf monocytes,in
R20 E1-ab-8 T10 objectOf ANG II,in
R21 E7-ab-9 T11 subjectOf monocytes,human monocytes
R22 E6-ab-9 T11 objectOf human,human monocytes
R23 E7-ab-9 T12 subjectOf monocytes,in
R24 E4-ab-9 T12 objectOf ANG II,in

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-107 Sentence denotes Angiotensin II activates the proinflammatory transcription factor nuclear factor-kappaB in human monocytes.
S2 108-191 Sentence denotes The renin-angiotensin system may contribute to the pathogenesis of atherosclerosis.
S3 192-277 Sentence denotes A common feature of all stages of atherosclerosis is inflammation of the vessel wall.
S4 278-402 Sentence denotes The transcription factor nuclear factor-kappaB (NF-kappaB) participates in most signaling pathways involved in inflammation.
S5 403-598 Sentence denotes This study therefore examined the effect of angiotensin (ANG) II on NF-kappaB activation in monocytic cells, a major cellular component of human atheroma, by electrophoretic mobility shift assay.
S6 599-744 Sentence denotes ANG II, like TNFalpha, caused rapid activation of NF-kappaB in human mononuclear cells isolated from peripheral blood by Ficoll density gradient.
S7 745-828 Sentence denotes This ANG II effect was blocked by the angiotensin AT1 receptor antagonist losartan.
S8 829-938 Sentence denotes Specificity of ANG II-induced NF-kappaB activation was ascertained by supershift and competition experiments.
S9 939-1057 Sentence denotes Moreover, ANG II stimulated NF-kappaB activation in human monocytes, but not in lymphocytes from the same preparation.
S10 1058-1187 Sentence denotes Together, the data demonstrate the ability of the vasoactive peptide ANG II to activate inflammatory pathways in human monocytes.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-14 NP denotes Angiotensin II
C2 91-106 NP denotes human monocytes
C3 175-190 NP denotes atherosclerosis
C4 226-241 NP denotes atherosclerosis
C5 278-336 NP denotes The transcription factor nuclear factor-kappaB (NF-kappaB)
C7 447-467 NP denotes angiotensin (ANG) II
C8 512-556 NP denotes a major cellular component of human atheroma
C6 433-556 NP denotes the effect of angiotensin (ANG) II on NF-kappaB activation in monocytic cells, a major cellular component of human atheroma
C9 599-605 NP denotes ANG II
C10 649-658 NP denotes NF-kappaB
C11 745-763 NP denotes This ANG II effect
C12 949-955 NP denotes ANG II
C13 991-1006 NP denotes human monocytes
C14 1104-1133 NP denotes the vasoactive peptide ANG II
C15 1171-1186 NP denotes human monocytes
R1 C4 C3 coref-ident atherosclerosis,atherosclerosis
R2 C7 C1 coref-ident angiotensin (ANG) II,Angiotensin II
R3 C8 C7 coref-appos a major cellular component of human atheroma,angiotensin (ANG) II
R4 C9 C7 coref-ident ANG II,angiotensin (ANG) II
R5 C10 C5 coref-ident NF-kappaB,The transcription factor nuclear factor-kappaB (NF-kappaB)
R6 C11 C6 coref-ident This ANG II effect,"the effect of angiotensin (ANG) II on NF-kappaB activation in monocytic cells, a major cellular component of human atheroma"
R7 C12 C9 coref-ident ANG II,ANG II
R8 C13 C2 coref-ident human monocytes,human monocytes
R9 C14 C12 coref-ident the vasoactive peptide ANG II,ANG II
R10 C15 C13 coref-ident human monocytes,human monocytes

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-14 protein_molecule denotes Angiotensin II
T2 29-65 protein_family_or_group denotes proinflammatory transcription factor
T3 66-87 protein_complex denotes nuclear factor-kappaB
T4 91-106 cell_type denotes human monocytes
T5 112-117 protein_molecule denotes renin
T6 117-129 peptide denotes -angiotensin
T7 175-190 other_name denotes atherosclerosis
T8 226-241 other_name denotes atherosclerosis
T9 245-257 other_name denotes inflammation
T10 265-276 tissue denotes vessel wall
T11 303-324 protein_complex denotes nuclear factor-kappaB
T12 326-335 protein_complex denotes NF-kappaB
T13 358-376 other_name denotes signaling pathways
T14 389-401 other_name denotes inflammation
T15 447-467 protein_molecule denotes angiotensin (ANG) II
T16 471-480 protein_complex denotes NF-kappaB
T17 495-510 cell_type denotes monocytic cells
T18 542-556 tissue denotes human atheroma
T19 561-597 other_name denotes electrophoretic mobility shift assay
T20 599-605 protein_molecule denotes ANG II
T21 612-620 protein_molecule denotes TNFalpha
T22 649-658 protein_molecule denotes NF-kappaB
T23 662-685 cell_type denotes human mononuclear cells
T24 700-716 tissue denotes peripheral blood
T25 720-743 other_name denotes Ficoll density gradient
T26 750-756 protein_molecule denotes ANG II
T27 783-818 other_organic_compound denotes angiotensin AT1 receptor antagonist
T28 819-827 other_organic_compound denotes losartan
T29 844-850 protein_molecule denotes ANG II
T30 859-868 protein_complex denotes NF-kappaB
T31 949-955 protein_molecule denotes ANG II
T32 967-976 protein_complex denotes NF-kappaB
T33 991-1006 cell_type denotes human monocytes
T34 1019-1030 cell_type denotes lymphocytes
T35 1108-1126 peptide denotes vasoactive peptide
T36 1127-1133 protein_molecule denotes ANG II
T37 1146-1167 other_name denotes inflammatory pathways
T38 1171-1186 cell_type denotes human monocytes

metamap-sample

Id Subject Object Predicate Lexical cue
T11 0-14 C0003009 denotes Angiotensin II
T23 15-24 C1515877 denotes activates
T21 45-65 C0040648 denotes transcription factor
T5 91-96 C0086418 denotes human
T14 97-106 C0026473 denotes monocytes
T30 112-136 C0035096 denotes renin-angiotensin system
T65 141-151 C1880177 denotes contribute
T66 159-171 C0543483 denotes pathogenesis
T25 175-190 C0004153 denotes atherosclerosis
T74 194-200 C1522138 denotes common
T64 201-208 C1521970 denotes feature
T60 216-222 C1306673 denotes stages
T24 226-241 C0004153 denotes atherosclerosis
T28 245-257 C0021368 denotes inflammation
T43 265-271 C0005847 denotes vessel
T73 272-276 C0677535 denotes wall
T20 282-302 C0040648 denotes transcription factor
T19 303-324 C0079904 denotes nuclear factor-kappaB
T33 358-376 C0037080 denotes signaling pathways
T58 377-385 C1314939 denotes involved
T27 389-401 C0021368 denotes inflammation
T52 408-413 C2603343 denotes study
T46 424-432 C0332128 denotes examined
T42 437-443 C1280500 denotes effect
T18 471-480 C0079904 denotes NF-kappaB
T37 481-491 C1879547 denotes activation
T13 495-504 C0026473 denotes monocytic
T50 505-510 C0007634 denotes cells
T76 514-519 C0205164 denotes major
T61 520-538 C1166607 denotes cellular component
T4 542-547 C0086418 denotes human
T40 548-556 C0264956 denotes atheroma
T32 561-597 C0949632 denotes electrophoretic mobility shift assay
T10 599-605 C0003009 denotes ANG II
T31 612-620 C0041368 denotes TNFalpha
T38 622-628 C0015127 denotes caused
T75 629-634 C0439831 denotes rapid
T36 635-645 C1879547 denotes activation
T17 649-658 C0079904 denotes NF-kappaB
T3 662-667 C0086418 denotes human
T56 668-679 C1513475 denotes mononuclear
T49 668-685 C0806987 denotes mononuclear cells
T62 686-694 C1548221 denotes isolated
T54 700-716 C0229664 denotes peripheral blood
T39 720-726 C0016071 denotes Ficoll
T57 727-734 C0178587 denotes density
T55 735-743 C0812409 denotes gradient
T9 750-756 C0003009 denotes ANG II
T41 757-763 C1280500 denotes effect
T68 768-775 C0332206 denotes blocked
T67 808-818 C0231491 denotes antagonist
T26 819-827 C0126174 denotes losartan
T69 829-840 C1511884 denotes Specificity
T8 844-850 C0003009 denotes ANG II
T77 851-858 C0205263 denotes induced
T16 859-868 C0079904 denotes NF-kappaB
T35 869-879 C1879547 denotes activation
T71 914-925 C0679932 denotes competition
T53 926-937 C0681814 denotes experiments
T7 949-955 C0003009 denotes ANG II
T47 956-966 C1948023 denotes stimulated
T15 967-976 C0079904 denotes NF-kappaB
T2 991-996 C0086418 denotes human
T59 1012-1015 C1518422 denotes not
T29 1019-1030 C0024264 denotes lymphocytes
T70 1040-1044 C0445247 denotes same
T51 1045-1056 C1521827 denotes preparation
T48 1058-1066 C1883357 denotes Together
T45 1072-1076 C1511726 denotes data
T34 1093-1100 C0085732 denotes ability
T78 1108-1118 C1980011 denotes vasoactive
T44 1119-1126 C0030956 denotes peptide
T6 1127-1133 C0003009 denotes ANG II
T22 1137-1145 C1515877 denotes activate
T72 1146-1158 C0333348 denotes inflammatory
T63 1159-1167 C1704259 denotes pathways
T1 1171-1176 C0086418 denotes human
T12 1177-1186 C0026473 denotes monocytes

DisGeNET

Id Subject Object Predicate Lexical cue
T0 112-117 gene:5972 denotes renin
T1 175-190 disease:C0003850 denotes atherosclerosis
T2 112-117 gene:5972 denotes renin
T3 175-190 disease:C0004153 denotes atherosclerosis
R1 T0 T1 associated_with renin,atherosclerosis
R2 T2 T3 associated_with renin,atherosclerosis

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 175-190 HP_0002621 denotes atherosclerosis
T2 226-241 HP_0002621 denotes atherosclerosis