> top > docs > PubMed:10203577 > annotations

PubMed:10203577 JSONTXT

Annnotations TAB JSON ListView MergeView

PMID_GLOBAL

Id Subject Object Predicate Lexical cue mondo_id
T1 202-217 DiseaseOrPhenotypicFeature denotes atherosclerosis 0005311
T2 727-748 DiseaseOrPhenotypicFeature denotes myocardial infarction 0005068
T3 752-755 DiseaseOrPhenotypicFeature denotes men 0017169
T4 1597-1606 DiseaseOrPhenotypicFeature denotes influenza 0005812
T5 1702-1707 DiseaseOrPhenotypicFeature denotes tumor 0005070
T6 2359-2362 DiseaseOrPhenotypicFeature denotes can 0012833
T7 2601-2616 DiseaseOrPhenotypicFeature denotes atherosclerosis 0005311

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 51-73 cell_type denotes human endothelial cell
T2 102-121 protein denotes heat shock proteins
T3 268-289 protein denotes heat shock protein 60
T4 291-296 protein denotes Hsp60
T5 319-341 cell_line denotes Hsp60-specific T cells
T6 356-373 cell_type denotes endothelial cells
T7 375-377 cell_type denotes EC
T8 406-411 protein denotes Hsp60
T9 424-442 protein denotes adhesion molecules
T10 481-483 cell_type denotes EC
T11 891-893 cell_type denotes EC
T12 1093-1111 protein denotes adhesion molecules
T13 1113-1147 protein denotes monocyte chemoattractant protein-1
T14 1149-1154 protein denotes MCP-1
T15 1161-1166 protein denotes Hsp60
T16 1170-1208 cell_type denotes human umbilical vein endothelial cells
T17 1210-1216 cell_type denotes HUVECs
T18 1293-1314 protein denotes transcription factors
T19 1315-1336 protein denotes nuclear factor kappaB
T20 1338-1347 protein denotes NF-kappaB
T21 1353-1372 protein denotes heat shock factor-1
T22 1374-1379 protein denotes HSF-1
T23 1597-1620 protein denotes influenza virus antigen
T24 1702-1729 protein denotes tumor necrosis factor-alpha
T25 1731-1740 protein denotes TNF-alpha
T26 1782-1788 cell_type denotes HUVECs
T27 1885-1894 protein denotes NF-kappaB
T28 1907-1909 cell_type denotes EC
T29 1951-1956 protein denotes Hsp60
T30 2041-2046 protein denotes Hsp70
T31 2061-2067 cell_type denotes HUVECs
T32 2102-2107 protein denotes HSF-1
T33 2303-2320 protein denotes adhesion molecule
T34 2370-2375 protein denotes Hsp60
T35 2379-2385 cell_type denotes HUVECs
T36 2545-2563 cell_type denotes sensitized T cells
T37 2576-2578 cell_type denotes EC
T38 2686-2691 protein denotes Hsp60
T39 2738-2755 protein denotes adhesion molecule
T40 2770-2772 cell_type denotes EC
T41 2806-2811 protein denotes MCP-1
T42 2873-2882 cell_type denotes monocytes
T43 2925-2927 cell_type denotes EC

semrep-sample

Id Subject Object Predicate Lexical cue
E1-ti-1 0-11 cui:C0205367 denotes Suppressive
E2-ti-1 12-19 cui:C1280500 denotes effects
E3-ti-1 23-47 cui:C0003209 denotes anti-inflammatory agents
E4-ti-1 51-56 cui:C0020114 denotes human
E5-ti-1 57-84 cui:C1155002 denotes endothelial cell activation
E6-ti-1 89-98 cui:C0857127 denotes induction
E7-ti-1 102-121 cui:C0018850 denotes heat shock proteins
T1 12-19 INTERACTS_WITH denotes effects
T2 51-84 PROCESS_OF denotes human endothelial cell activation
E1-ab-1 135-142 cui:C0008972 denotes Studies
E2-ab-1 152-162 cui:C0022877 denotes laboratory
E3-ab-1 183-191 cui:C1279919 denotes earliest
E4-ab-1 192-198 cui:C1306673 denotes stages
E5-ab-1 202-217 cui:C0004153 denotes atherosclerosis
E6-ab-1 240-259 cui:C0301931 denotes autoimmune reaction
E7-ab-1 268-289 cui:C0109272 denotes heat shock protein 60
T3 143-147 LOCATION_OF denotes from
T4 225-233 AFFECTS denotes mediated
E1-ab-2 319-324 cui:C0109272 denotes Hsp60
E2-ab-2 336-341 cui:C0007634 denotes cells
E3-ab-2 347-355 cui:C0221464 denotes arterial
E4-ab-2 356-373 cui:C0225336 denotes endothelial cells
E5-ab-2 387-397 cui:C0185117 denotes expression
E6-ab-2 406-411 cui:C0109272 denotes Hsp60
E7-ab-2 416-423 cui:C0205423 denotes certain
E8-ab-2 424-442 cui:C0007578 denotes adhesion molecules
E9-ab-2 481-483 cui:C0225336 denotes EC
E10-ab-2 508-513 cui:C0332307 denotes types
E11-ab-2 517-523 cui:C0038435 denotes stress
T5 455-462 AUGMENTS denotes induced
E1-ab-3 525-533 cui:C0332185 denotes Recently
E2-ab-3 553-564 cui:C0439181 denotes suppression
E3-ab-3 570-600 cui:C1318468 denotes cell-mediated immune responses
E4-ab-3 604-617 cui:C0010592 denotes cyclosporin A
E5-ab-3 633-648 cui:C0333482 denotes atherosclerotic
E6-ab-3 624-655 cui:C1333400 denotes enhanced atherosclerotic lesion
E7-ab-3 656-665 cui:C1522492 denotes formation
E8-ab-3 669-673 cui:C0026809 denotes mice
T6 666-668 PROCESS_OF denotes in
E1-ab-4 688-695 cui:C0004057 denotes aspirin
E2-ab-4 719-723 cui:C0035647 denotes risk
E3-ab-4 727-748 cui:C0027051 denotes myocardial infarction
E4-ab-4 752-755 cui:C0025266 denotes men
T7 719-723 PREDISPOSES denotes risk
T8 749-751 PROCESS_OF denotes in
E1-ab-5 802-811 cui:C1547020 denotes different
E2-ab-5 812-819 cui:C1280500 denotes effects
E3-ab-5 823-847 cui:C0003209 denotes anti-inflammatory agents
E4-ab-5 851-868 cui:C0007578 denotes adhesion molecule
E5-ab-5 873-876 cui:C0018850 denotes Hsp
E6-ab-5 877-887 cui:C0185117 denotes expression
E7-ab-5 891-893 cui:C0225336 denotes EC
T9 812-819 INTERACTS_WITH denotes effects
T10 812-819 INTERACTS_WITH denotes effects
T11 888-890 LOCATION_OF denotes in
T12 888-890 LOCATION_OF denotes in
E1-ab-6 909-917 cui:C0520510 denotes MATERIAL
E2-ab-6 922-929 cui:C0025663 denotes METHODS
E3-ab-6 938-945 cui:C0150312 denotes present
E4-ab-6 946-951 cui:C0008972 denotes study
E5-ab-6 969-976 cui:C1280500 denotes effects
E6-ab-6 980-983 cui:C0010592 denotes CyA
E7-ab-6 985-992 cui:C0004057 denotes aspirin
E8-ab-6 998-1010 cui:C0021246 denotes indomethacin
E9-ab-6 1014-1034 cui:C1155046 denotes T cell proliferation
E10-ab-6 1043-1056 cui:C0334094 denotes proliferation
E11-ab-6 1057-1062 cui:C1510438 denotes assay
T13 969-976 INTERACTS_WITH denotes effects
E1-ab-7 1079-1089 cui:C0185117 denotes expression
E2-ab-7 1093-1111 cui:C0007578 denotes adhesion molecules
E3-ab-7 1113-1147 cui:C0128897 denotes monocyte chemoattractant protein-1
E4-ab-7 1161-1166 cui:C0109272 denotes Hsp60
E5-ab-7 1170-1175 cui:C0020114 denotes human
E6-ab-7 1176-1190 cui:C0041637 denotes umbilical vein
E7-ab-7 1191-1208 cui:C0225336 denotes endothelial cells
E8-ab-7 1219-1241 cui:C0005861 denotes Northern blot analyses
T14 1079-1089 PART_OF denotes expression
E1-ab-8 1279-1285 cui:C0449438 denotes status
E2-ab-8 1293-1314 cui:C0040648 denotes transcription factors
E3-ab-8 1315-1322 cui:C0521447 denotes nuclear
E4-ab-8 1353-1363 cui:C0282498 denotes heat shock
E5-ab-8 1364-1370 cui:C1521761 denotes factor
E6-ab-8 1382-1419 cui:C0949632 denotes electrophoretic mobility shift assays
E1-ab-9 1436-1443 cui:C1274040 denotes RESULTS
E2-ab-9 1454-1463 cui:C1554961 denotes exception
E3-ab-9 1467-1479 cui:C0021246 denotes indomethacin
E4-ab-9 1485-1489 cui:C0042153 denotes used
E5-ab-9 1512-1536 cui:C0003209 denotes anti-inflammatory agents
E6-ab-9 1561-1581 cui:C1155046 denotes T cell proliferation
E7-ab-9 1585-1593 cui:C0871261 denotes response
E8-ab-9 1597-1620 cui:C0450099 denotes influenza virus antigen
E9-ab-9 1626-1640 cui:C1512045 denotes dose-dependent
T15 1551-1560 DISRUPTS denotes inhibited
T16 1551-1560 DISRUPTS denotes inhibited
E1-ab-10 1664-1667 cui:C0010592 denotes CyA
E2-ab-10 1672-1684 cui:C0021246 denotes indomethacin
E3-ab-10 1689-1692 cui:C1518422 denotes not
E4-ab-10 1702-1729 cui:C1448177 denotes tumor necrosis factor-alpha
E5-ab-10 1742-1749 cui:C0205263 denotes induced
E6-ab-10 1750-1767 cui:C0007578 denotes adhesion molecule
E7-ab-10 1768-1778 cui:C0185117 denotes expression
E8-ab-10 1782-1788 cui:C0020114 denotes HUVECs
E9-ab-10 1782-1788 cui:C0041637 denotes HUVECs
E10-ab-10 1782-1788 cui:C0225336 denotes HUVECs
E11-ab-10 1798-1805 cui:C0004057 denotes aspirin
E12-ab-10 1813-1823 cui:C0243077 denotes inhibitory
E13-ab-10 1824-1830 cui:C1280500 denotes effect
T17 1693-1701 INHIBITS denotes suppress
T18 1693-1701 INHIBITS denotes suppress
T19 1779-1781 LOCATION_OF denotes on
E1-ab-11 1885-1894 cui:C0521447 denotes NF-kappaB
E2-ab-11 1885-1894 cui:C1521761 denotes NF-kappaB
E3-ab-11 1895-1903 cui:C0439167 denotes activity
E4-ab-11 1907-1909 cui:C0225336 denotes EC
E1-ab-12 1915-1921 cui:C0450442 denotes agents
E2-ab-12 1929-1936 cui:C0205263 denotes induced
E3-ab-12 1937-1947 cui:C0185117 denotes expression
E4-ab-12 1951-1956 cui:C0109272 denotes Hsp60
E5-ab-12 1968-1979 cui:C0185125 denotes application
E1-ab-13 1984-1992 cui:C0442796 denotes addition
E2-ab-13 1994-2001 cui:C0004057 denotes aspirin
E3-ab-13 2006-2018 cui:C0021246 denotes indomethacin
E4-ab-13 2024-2027 cui:C1518422 denotes not
E5-ab-13 2028-2031 cui:C0010592 denotes CyA
E6-ab-13 2033-2040 cui:C0205263 denotes induced
E7-ab-13 2041-2046 cui:C0243043 denotes Hsp70
E8-ab-13 2047-2057 cui:C0185117 denotes expression
E9-ab-13 2061-2067 cui:C0020114 denotes HUVECs
E10-ab-13 2061-2067 cui:C0041637 denotes HUVECs
E11-ab-13 2061-2067 cui:C0225336 denotes HUVECs
E12-ab-13 2089-2098 cui:C0857127 denotes induction
E13-ab-13 2102-2107 cui:C0282498 denotes HSF-1
E14-ab-13 2102-2107 cui:C1521761 denotes HSF-1
E15-ab-13 2108-2116 cui:C0439167 denotes activity
T20 2033-2040 AUGMENTS denotes induced
T21 2033-2040 AUGMENTS denotes induced
T22 2102-2107 AFFECTS denotes HSF-1
E1-ab-14 2134-2141 cui:C1274040 denotes results
E2-ab-14 2156-2162 cui:C0039593 denotes tested
E3-ab-14 2163-2169 cui:C0450442 denotes agents
E4-ab-14 2178-2190 cui:C0021246 denotes indomethacin
E5-ab-14 2196-2206 cui:C0243077 denotes inhibitors
E6-ab-14 2216-2245 cui:C1318468 denotes cell-mediated immune response
E7-ab-14 2265-2272 cui:C0004057 denotes aspirin
E8-ab-14 2279-2288 cui:C1280500 denotes effective
E9-ab-14 2303-2320 cui:C0007578 denotes adhesion molecule
E10-ab-14 2321-2331 cui:C0185117 denotes expression
E11-ab-14 2346-2351 cui:C0205449 denotes three
E12-ab-14 2352-2358 cui:C0450442 denotes agents
E13-ab-14 2370-2375 cui:C0109272 denotes Hsp60
E14-ab-14 2379-2385 cui:C0020114 denotes HUVECs
E15-ab-14 2379-2385 cui:C0041637 denotes HUVECs
E16-ab-14 2379-2385 cui:C0225336 denotes HUVECs
T23 2196-2206 DISRUPTS denotes inhibitors
T24 2363-2369 STIMULATES denotes induce
T25 2376-2378 LOCATION_OF denotes in
E1-ab-15 2393-2397 cui:C1511726 denotes data
E2-ab-15 2410-2419 cui:C1521991 denotes molecular
E3-ab-15 2420-2425 cui:C1527178 denotes basis
E4-ab-15 2450-2454 cui:C0449719 denotes part
E5-ab-15 2479-2485 cui:C1280500 denotes effect
E6-ab-15 2489-2496 cui:C0004057 denotes aspirin
E7-ab-15 2515-2525 cui:C0687732 denotes prevention
E8-ab-15 2533-2541 cui:C0001511 denotes adhesion
E9-ab-15 2556-2563 cui:C0039194 denotes T cells
E10-ab-15 2567-2575 cui:C0038435 denotes stressed
E11-ab-15 2576-2578 cui:C0225336 denotes EC
T26 2515-2525 PREVENTS denotes prevention
T27 2542-2544 LOCATION_OF denotes of
E1-ab-16 2589-2593 cui:C0449719 denotes part
E2-ab-16 2601-2616 cui:C0004153 denotes atherosclerosis
E3-ab-16 2627-2633 cui:C1280500 denotes effect
E4-ab-16 2637-2640 cui:C0010592 denotes CyA
E5-ab-16 2659-2668 cui:C0237399 denotes potential
E6-ab-16 2686-2691 cui:C0109272 denotes Hsp60
E7-ab-16 2692-2702 cui:C0185117 denotes expression
E8-ab-16 2738-2755 cui:C0007578 denotes adhesion molecule
E9-ab-16 2756-2766 cui:C0185117 denotes expression
E10-ab-16 2770-2772 cui:C0225336 denotes EC
T28 2627-2633 INTERACTS_WITH denotes effect
T29 2767-2769 LOCATION_OF denotes on
E1-ab-17 2787-2802 cui:C0013081 denotes down-regulation
E2-ab-17 2806-2811 cui:C0128897 denotes MCP-1
E3-ab-17 2812-2822 cui:C0185117 denotes expression
E4-ab-17 2826-2833 cui:C0004057 denotes aspirin
E5-ab-17 2848-2857 cui:C0205216 denotes decreased
E6-ab-17 2873-2882 cui:C0026473 denotes monocytes
E7-ab-17 2892-2907 cui:C0162862 denotes arterial intima
E8-ab-17 2916-2924 cui:C0038435 denotes stressed
E9-ab-17 2925-2927 cui:C0225336 denotes EC
R1 E7-ti-1 T1 subjectOf heat shock proteins,effects
R2 E3-ti-1 T1 objectOf anti-inflammatory agents,effects
R3 E5-ti-1 T2 subjectOf endothelial cell activation,human endothelial cell activation
R4 E4-ti-1 T2 objectOf human,human endothelial cell activation
R5 E2-ab-1 T3 subjectOf laboratory,from
R6 E1-ab-1 T3 objectOf Studies,from
R7 E6-ab-1 T4 subjectOf autoimmune reaction,mediated
R8 E5-ab-1 T4 objectOf atherosclerosis,mediated
R9 E8-ab-2 T5 subjectOf adhesion molecules,induced
R10 E9-ab-2 T5 objectOf EC,induced
R11 E3-ab-3 T6 subjectOf cell-mediated immune responses,in
R12 E8-ab-3 T6 objectOf mice,in
R13 E1-ab-4 T7 subjectOf aspirin,risk
R14 E3-ab-4 T7 objectOf myocardial infarction,risk
R15 E3-ab-4 T8 subjectOf myocardial infarction,in
R16 E4-ab-4 T8 objectOf men,in
R17 E3-ab-5 T9 subjectOf anti-inflammatory agents,effects
R18 E4-ab-5 T9 objectOf adhesion molecule,effects
R19 E3-ab-5 T10 subjectOf anti-inflammatory agents,effects
R20 E5-ab-5 T10 objectOf Hsp,effects
R21 E7-ab-5 T11 subjectOf EC,in
R22 E5-ab-5 T11 objectOf Hsp,in
R23 E7-ab-5 T12 subjectOf EC,in
R24 E4-ab-5 T12 objectOf adhesion molecule,in
R25 E7-ab-6 T13 subjectOf aspirin,effects
R26 E6-ab-6 T13 objectOf CyA,effects
R27 E4-ab-7 T14 subjectOf Hsp60,expression
R28 E7-ab-7 T14 objectOf endothelial cells,expression
R29 E5-ab-9 T15 subjectOf anti-inflammatory agents,inhibited
R30 E6-ab-9 T15 objectOf T cell proliferation,inhibited
R31 E3-ab-9 T16 subjectOf indomethacin,inhibited
R32 E6-ab-9 T16 objectOf T cell proliferation,inhibited
R33 E2-ab-10 T17 subjectOf indomethacin,suppress
R34 E6-ab-10 T17 objectOf adhesion molecule,suppress
R35 E1-ab-10 T18 subjectOf CyA,suppress
R36 E6-ab-10 T18 objectOf adhesion molecule,suppress
R37 E10-ab-10 T19 subjectOf HUVECs,on
R38 E6-ab-10 T19 objectOf adhesion molecule,on
R39 E5-ab-13 T20 subjectOf CyA,induced
R40 E11-ab-13 T20 objectOf HUVECs,induced
R41 E3-ab-13 T21 subjectOf indomethacin,induced
R42 E11-ab-13 T21 objectOf HUVECs,induced
R43 E12-ab-13 T22 subjectOf induction,HSF-1
R44 E13-ab-13 T22 objectOf HSF-1,HSF-1
R45 E4-ab-14 T23 subjectOf indomethacin,inhibitors
R46 E6-ab-14 T23 objectOf cell-mediated immune response,inhibitors
R47 E9-ab-14 T24 subjectOf adhesion molecule,induce
R48 E13-ab-14 T24 objectOf Hsp60,induce
R49 E16-ab-14 T25 subjectOf HUVECs,in
R50 E13-ab-14 T25 objectOf Hsp60,in
R51 E6-ab-15 T26 subjectOf aspirin,prevention
R52 E8-ab-15 T26 objectOf adhesion,prevention
R53 E9-ab-15 T27 subjectOf T cells,of
R54 E8-ab-15 T27 objectOf adhesion,of
R55 E8-ab-16 T28 subjectOf adhesion molecule,effect
R56 E4-ab-16 T28 objectOf CyA,effect
R57 E10-ab-16 T29 subjectOf EC,on
R58 E8-ab-16 T29 objectOf adhesion molecule,on

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-122 Sentence denotes Suppressive effects of anti-inflammatory agents on human endothelial cell activation and induction of heat shock proteins.
S2 123-298 Sentence denotes BACKGROUND: Studies from our laboratory have shown that the earliest stages of atherosclerosis may be mediated by an autoimmune reaction against heat shock protein 60 (Hsp60).
S3 299-524 Sentence denotes The interactions of Hsp60-specific T cells with arterial endothelial cells (EC) require expression of both Hsp60 and certain adhesion molecules shown to be induced simultaneously in EC by mechanical and other types of stress.
S4 525-674 Sentence denotes Recently, it was shown that suppression of T cell-mediated immune responses by cyclosporin A (CyA) enhanced atherosclerotic lesion formation in mice.
S5 675-756 Sentence denotes In contrast, aspirin was found to lower the risk of myocardial infarction in men.
S6 757-908 Sentence denotes These conflicting observations may be due to different effects of anti-inflammatory agents on adhesion molecule and Hsp expression in EC, respectively.
S7 909-1063 Sentence denotes MATERIAL AND METHODS: In the present study, we analyzed the effects of CyA, aspirin, and indomethacin on T cell proliferation using a proliferation assay.
S8 1064-1252 Sentence denotes To explore the expression of adhesion molecules, monocyte chemoattractant protein-1 (MCP-1), and Hsp60 in human umbilical vein endothelial cells (HUVECs), Northern blot analyses were used.
S9 1253-1435 Sentence denotes To examine the activation status of the transcription factors nuclear factor kappaB (NF-kappaB) and heat shock factor-1 (HSF-1), electrophoretic mobility shift assays were performed.
S10 1436-1648 Sentence denotes RESULTS: With the exception of indomethacin, the used immunosuppressive and anti-inflammatory agents significantly inhibited T cell proliferation in response to influenza virus antigen in a dose-dependent manner.
S11 1649-1831 Sentence denotes Interestingly, CyA and indomethacin did not suppress tumor necrosis factor-alpha (TNF-alpha)-induced adhesion molecule expression on HUVECs, whereas aspirin had an inhibitory effect.
S12 1832-1910 Sentence denotes These observations correlated with the modulation of NF-kappaB activity in EC.
S13 1911-1980 Sentence denotes All agents tested induced expression of Hsp60 6 hr after application.
S14 1981-2117 Sentence denotes In addition, aspirin and indomethacin, but not CyA, induced Hsp70 expression in HUVECs that correlated with induction of HSF-1 activity.
S15 2118-2386 Sentence denotes CONCLUSION: Our results show that the tested agents (except indomethacin) are inhibitors of the T cell-mediated immune response, as expected, that aspirin is an effective suppressor of adhesion molecule expression, and that all three agents can induce Hsp60 in HUVECs.
S16 2387-2928 Sentence denotes These data provide the molecular basis for the notion that (1) part of the anti-atherogenic effect of aspirin may be due to the prevention of the adhesion of sensitized T cells to stressed EC; (2) that part of the atherosclerosis-promoting effect of CyA may be due to its potential as an inducer of Hsp60 expression and its inability to down-regulate adhesion molecule expression on EC; and (3) that down-regulation of MCP-1 expression by aspirin may result in decreased recruitment of monocytes into the arterial intima beneath stressed EC.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 23-47 NP denotes anti-inflammatory agents
C2 268-297 NP denotes heat shock protein 60 (Hsp60)
C3 481-483 NP denotes EC
C4 604-623 NP denotes cyclosporin A (CyA)
C5 688-695 NP denotes aspirin
C6 823-847 NP denotes anti-inflammatory agents
C7 891-893 NP denotes EC
C9 980-983 NP denotes CyA
C10 985-992 NP denotes aspirin
C11 998-1010 NP denotes indomethacin
C8 980-1010 NP denotes CyA, aspirin, and indomethacin
C12 1014-1034 NP denotes T cell proliferation
C13 1093-1111 NP denotes adhesion molecules
C16 1170-1217 NP denotes human umbilical vein endothelial cells (HUVECs)
C15 1161-1217 NP denotes Hsp60 in human umbilical vein endothelial cells (HUVECs)
C14 1113-1217 NP denotes monocyte chemoattractant protein-1 (MCP-1), and Hsp60 in human umbilical vein endothelial cells (HUVECs)
C17 1467-1479 NP denotes indomethacin
C18 1561-1581 NP denotes T cell proliferation
C19 1664-1667 NP denotes CyA
C20 1672-1684 NP denotes indomethacin
C21 1782-1788 NP denotes HUVECs
C22 1798-1805 NP denotes aspirin
C23 1907-1909 NP denotes EC
C24 1911-1928 NP denotes All agents tested
C26 1951-1956 NP denotes Hsp60
C25 1937-1956 NP denotes expression of Hsp60
C27 1994-2001 NP denotes aspirin
C28 2006-2018 NP denotes indomethacin
C29 2028-2031 NP denotes CyA
C31 2061-2067 NP denotes HUVECs
C30 2041-2067 NP denotes Hsp70 expression in HUVECs
C32 2068-2072 NP denotes that
C33 2265-2272 NP denotes aspirin
C34 2342-2358 NP denotes all three agents
C36 2379-2385 NP denotes HUVECs
C35 2370-2385 NP denotes Hsp60 in HUVECs
C37 2430-2440 NP denotes the notion
C38 2441-2445 NP denotes that
C39 2489-2496 NP denotes aspirin
C40 2567-2579 NP denotes stressed EC;
C41 2637-2640 NP denotes CyA
C42 2655-2658 NP denotes its
C43 2686-2702 NP denotes Hsp60 expression
C44 2707-2710 NP denotes its
C45 2770-2773 NP denotes EC;
C46 2826-2833 NP denotes aspirin
C47 2916-2927 NP denotes stressed EC
R1 C6 C1 coref-ident anti-inflammatory agents,anti-inflammatory agents
R2 C7 C3 coref-ident EC,EC
R3 C9 C4 coref-ident CyA,cyclosporin A (CyA)
R4 C10 C5 coref-ident aspirin,aspirin
R5 C14 C13 coref-appos "monocyte chemoattractant protein-1 (MCP-1), and Hsp60 in human umbilical vein endothelial cells (HUVECs)",adhesion molecules
R6 C17 C11 coref-ident indomethacin,indomethacin
R7 C18 C12 coref-ident T cell proliferation,T cell proliferation
R8 C19 C9 coref-ident CyA,CyA
R9 C20 C17 coref-ident indomethacin,indomethacin
R10 C21 C16 coref-ident HUVECs,human umbilical vein endothelial cells (HUVECs)
R11 C22 C10 coref-ident aspirin,aspirin
R12 C23 C7 coref-ident EC,EC
R13 C24 C8 coref-ident All agents tested,"CyA, aspirin, and indomethacin"
R14 C26 C2 coref-ident Hsp60,heat shock protein 60 (Hsp60)
R15 C27 C22 coref-ident aspirin,aspirin
R16 C28 C20 coref-ident indomethacin,indomethacin
R17 C29 C19 coref-ident CyA,CyA
R18 C31 C21 coref-ident HUVECs,HUVECs
R19 C32 C30 coref-relat that,Hsp70 expression in HUVECs
R20 C33 C27 coref-ident aspirin,aspirin
R21 C34 C24 coref-ident all three agents,All agents tested
R22 C36 C31 coref-ident HUVECs,HUVECs
R23 C35 C15 coref-ident Hsp60 in HUVECs,Hsp60 in human umbilical vein endothelial cells (HUVECs)
R24 C38 C37 coref-relat that,the notion
R25 C39 C33 coref-ident aspirin,aspirin
R26 C41 C29 coref-ident CyA,CyA
R27 C42 C41 coref-pron its,CyA
R28 C43 C25 coref-ident Hsp60 expression,expression of Hsp60
R29 C44 C41 coref-pron its,CyA
R30 C45 C23 coref-ident EC;,EC
R31 C46 C39 coref-ident aspirin,aspirin
R32 C47 C40 coref-ident stressed EC,stressed EC;

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 23-47 other_organic_compound denotes anti-inflammatory agents
T2 51-73 cell_type denotes human endothelial cell
T3 102-121 protein_family_or_group denotes heat shock proteins
T4 240-259 other_name denotes autoimmune reaction
T5 268-289 protein_molecule denotes heat shock protein 60
T6 291-296 protein_molecule denotes Hsp60
T7 319-324 protein_molecule denotes Hsp60
T8 356-373 cell_type denotes endothelial cells
T9 375-377 cell_type denotes EC
T10 406-411 protein_molecule denotes Hsp60
T11 424-442 protein_family_or_group denotes adhesion molecules
T12 481-483 cell_type denotes EC
T13 568-600 other_name denotes T cell-mediated immune responses
T14 604-617 other_organic_compound denotes cyclosporin A
T15 619-622 other_organic_compound denotes CyA
T16 633-665 other_name denotes atherosclerotic lesion formation
T17 669-673 multi_cell denotes mice
T18 688-695 other_organic_compound denotes aspirin
T19 727-748 other_name denotes myocardial infarction
T20 752-755 multi_cell denotes men
T21 823-847 other_organic_compound denotes anti-inflammatory agents
T22 891-893 cell_type denotes EC
T23 980-983 other_organic_compound denotes CyA
T24 985-992 other_organic_compound denotes aspirin
T25 998-1010 other_organic_compound denotes indomethacin
T26 1014-1034 other_name denotes T cell proliferation
T27 1093-1111 protein_family_or_group denotes adhesion molecules
T28 1113-1147 protein_molecule denotes monocyte chemoattractant protein-1
T29 1149-1154 protein_molecule denotes MCP-1
T30 1161-1166 protein_molecule denotes Hsp60
T31 1170-1190 cell_type denotes human umbilical vein
T32 1191-1208 cell_type denotes endothelial cells
T33 1210-1216 cell_type denotes HUVECs
T34 1219-1241 other_name denotes Northern blot analyses
T35 1293-1314 protein_family_or_group denotes transcription factors
T36 1315-1336 protein_complex denotes nuclear factor kappaB
T37 1338-1347 protein_complex denotes NF-kappaB
T38 1353-1372 protein_molecule denotes heat shock factor-1
T39 1374-1379 protein_molecule denotes HSF-1
T40 1382-1419 other_name denotes electrophoretic mobility shift assays
T41 1467-1479 other_organic_compound denotes indomethacin
T42 1490-1507 other_name denotes immunosuppressive
T43 1512-1536 other_organic_compound denotes anti-inflammatory agents
T44 1561-1581 other_name denotes T cell proliferation
T45 1597-1620 protein_family_or_group denotes influenza virus antigen
T46 1626-1647 other_name denotes dose-dependent manner
T47 1664-1667 other_organic_compound denotes CyA
T48 1672-1684 other_organic_compound denotes indomethacin
T49 1702-1729 protein_molecule denotes tumor necrosis factor-alpha
T50 1731-1740 protein_molecule denotes TNF-alpha
T51 1782-1788 cell_type denotes HUVECs
T52 1798-1805 other_organic_compound denotes aspirin
T53 1813-1830 other_name denotes inhibitory effect
T54 1885-1894 protein_complex denotes NF-kappaB
T55 1907-1909 cell_type denotes EC
T56 1951-1956 protein_molecule denotes Hsp60
T57 1994-2001 other_organic_compound denotes aspirin
T58 2006-2018 other_organic_compound denotes indomethacin
T59 2028-2031 other_organic_compound denotes CyA
T60 2041-2046 protein_molecule denotes Hsp70
T61 2061-2067 cell_type denotes HUVECs
T62 2102-2107 protein_molecule denotes HSF-1
T63 2178-2190 other_organic_compound denotes indomethacin
T64 2214-2245 other_name denotes T cell-mediated immune response
T65 2265-2272 other_organic_compound denotes aspirin
T66 2303-2320 protein_family_or_group denotes adhesion molecule
T67 2370-2375 protein_molecule denotes Hsp60
T68 2379-2385 cell_type denotes HUVECs
T69 2462-2485 other_name denotes anti-atherogenic effect
T70 2489-2496 other_organic_compound denotes aspirin
T71 2545-2563 cell_type denotes sensitized T cells
T72 2576-2578 cell_type denotes EC
T73 2601-2633 other_name denotes atherosclerosis-promoting effect
T74 2637-2640 other_organic_compound denotes CyA
T75 2686-2691 protein_molecule denotes Hsp60
T76 2738-2755 protein_family_or_group denotes adhesion molecule
T77 2770-2772 cell_type denotes EC
T78 2806-2811 protein_molecule denotes MCP-1
T79 2826-2833 other_organic_compound denotes aspirin
T80 2873-2882 cell_type denotes monocytes
T81 2892-2907 tissue denotes arterial intima
T82 2925-2927 cell_type denotes EC

metamap-sample

Id Subject Object Predicate Lexical cue
T1 52-57 C0086418 denotes uman
T3 24-48 C0003209 denotes nti-inflammatory agents
T4 103-122 C0018850 denotes eat shock proteins.
T21 90-99 C0205263 denotes nduction
T27 13-20 C1280500 denotes ffects
T28 1-12 C0205367 denotes uppressive
T2 824-848 C0003209 denotes nti-inflammatory agents
T5 2928-908 C0004057 denotes
T6 2928-908 C0004057 denotes
T7 2928-908 C0004057 denotes
T8 2928-908 C0004057 denotes
T9 2928-908 C0004057 denotes
T10 2928-908 C0004057 denotes
T11 689-696 C0004057 denotes spirin
T12 2928-908 C0109272 denotes
T13 2928-908 C0109272 denotes
T14 2928-908 C0109272 denotes
T15 2928-908 C0109272 denotes
T16 2928-908 C0205263 denotes
T17 2928-908 C0205263 denotes
T18 2928-908 C0205263 denotes
T19 2928-908 C0205263 denotes
T20 456-463 C0205263 denotes nduced
T22 2928-908 C1280500 denotes
T23 2928-908 C1280500 denotes
T24 2928-908 C1280500 denotes
T25 2928-908 C1280500 denotes
T26 813-820 C1280500 denotes ffects
T29 2928-908 C0010592 denotes
T30 2928-908 C0010592 denotes
T31 2928-908 C0010592 denotes
T32 2928-908 C0010592 denotes
T33 605-618 C0010592 denotes yclosporin A
T34 2928-908 C0007578 denotes
T35 2928-908 C0007578 denotes
T36 852-869 C0007578 denotes dhesion molecule
T37 2928-908 C0021246 denotes
T38 2928-908 C0021246 denotes
T39 2928-908 C0021246 denotes
T40 2928-908 C0021246 denotes
T41 2928-908 C0021246 denotes
T42 2928-908 C0225336 denotes
T43 2928-908 C0225336 denotes
T44 2928-908 C0225336 denotes
T45 892-894 C0225336 denotes C,
T46 482-484 C0225336 denotes C
T47 357-374 C0225336 denotes ndothelial cells
T48 2928-908 C3179121 denotes
T49 2928-908 C3179121 denotes
T50 2928-908 C3179121 denotes
T51 2928-908 C3179121 denotes
T52 2928-908 C0128897 denotes
T53 2928-908 C0185117 denotes
T54 2928-908 C0185117 denotes
T55 2928-908 C0185117 denotes
T56 2928-908 C0185117 denotes
T57 2928-908 C0185117 denotes
T58 2928-908 C0185117 denotes
T59 878-888 C0185117 denotes xpression
T60 388-398 C0185117 denotes xpression
T61 2928-908 C0039194 denotes
T62 335-342 C0039194 denotes cells
T63 2928-908 C0004153 denotes
T64 203-218 C0004153 denotes therosclerosis
T65 670-674 C0026809 denotes ice.
T66 2928-908 C0079904 denotes
T67 2928-908 C0079904 denotes
T68 2928-908 C1883351 denotes
T69 2928-908 C1883351 denotes
T70 707-709 C1883351 denotes o
T71 450-452 C1883351 denotes o
T72 2928-908 C0302523 denotes
T73 776-788 C0302523 denotes bservations
T74 720-724 C0035647 denotes isk
T75 2928-908 C1456820 denotes
T76 2928-908 C0162862 denotes
T77 2928-908 C1547282 denotes
T78 543-548 C1547282 denotes hown
T79 444-449 C1547282 denotes hown
T80 169-174 C1547282 denotes hown
T81 2928-908 C0021081 denotes
T82 2928-908 C0001511 denotes
T83 2928-908 C0243043 denotes
T84 2928-908 C1563937 denotes
T85 2928-908 C0005861 denotes
T86 2928-908 C0949632 denotes
T87 2928-908 C0013081 denotes
T88 2928-908 C3463820 denotes
T89 728-748 C0027051 denotes yocardial infarction
T90 2928-908 C0025664 denotes
T91 2928-908 C1274040 denotes
T92 2928-908 C1274040 denotes
T93 2928-908 C1274040 denotes
T94 2928-908 C1254351 denotes
T95 2928-908 C0678226 denotes
T96 2928-908 C0678226 denotes
T97 796-802 C0678226 denotes ue to
T98 2928-908 C2987476 denotes
T99 2928-908 C2987476 denotes
T100 793-795 C2987476 denotes e
T101 2928-908 C0038435 denotes
T102 2928-908 C0038435 denotes
T103 518-524 C0038435 denotes tress.
T104 764-775 C0009671 denotes onflicting
T105 2928-908 C0040648 denotes
T106 753-756 C0025266 denotes en.
T107 2928-908 C0150312 denotes
T108 701-706 C0150312 denotes ound
T109 2928-908 C1415749 denotes
T110 2928-908 C1415749 denotes
T111 2928-908 C0392366 denotes
T112 2928-908 C0392366 denotes
T113 2928-908 C1273517 denotes
T114 2928-908 C1273517 denotes
T115 2928-908 C1518422 denotes
T116 2928-908 C1518422 denotes
T117 2928-908 C1155046 denotes
T118 2928-908 C1155046 denotes
T119 2928-908 C1292711 denotes
T120 2928-908 C1292711 denotes
T121 2928-908 C1707520 denotes
T122 2928-908 C1707520 denotes
T123 2928-908 C0005507 denotes
T124 657-666 C0220781 denotes ormation
T125 2928-908 C2827734 denotes
T126 2928-908 C2981700 denotes
T127 2928-908 C0439086 denotes
T128 2928-908 C1883712 denotes
T129 2928-908 C0936012 denotes
T130 2928-908 C0185125 denotes
T131 135-123 C1706907 denotes
T132 2928-908 C1707478 denotes
T133 679-687 C1979874 denotes ontrast,
T134 2928-908 C1511726 denotes
T135 2928-908 C1517001 denotes
T136 2928-908 C0311403 denotes
T137 710-715 C0441994 denotes ower
T138 2928-908 C0520510 denotes
T139 488-498 C0443254 denotes echanical
T140 2928-908 C0884358 denotes
T141 2928-908 C1999230 denotes
T142 526-534 C0332185 denotes ecently,
T143 2928-908 C1260953 denotes
T144 2928-908 C1524063 denotes
T145 2928-908 C1554961 denotes
T146 2928-908 C2603343 denotes
T147 241-260 C1963070 denotes utoimmune reaction
T148 2928-908 C0423866 denotes
T149 184-199 C2363430 denotes arliest stages
T150 2928-908 C1853126 denotes
T151 464-478 C0521115 denotes imultaneously
T152 509-514 C0332307 denotes ypes
T153 226-234 C0127400 denotes ediated
T154 2928-908 C3245505 denotes
T155 2928-908 C2949735 denotes
T156 2928-908 C1710252 denotes
T157 554-565 C0301625 denotes uppression
T158 2928-908 C0243077 denotes
T159 2928-908 C1561536 denotes
T160 803-812 C1705242 denotes ifferent
T161 2928-908 C0443264 denotes
T162 2928-908 C0449438 denotes
T163 2928-908 C0199176 denotes
T164 2928-908 C1512045 denotes
T165 304-316 C1704675 denotes nteractions
T166 2928-908 C0334094 denotes
T167 2928-908 C0205449 denotes
T168 348-355 C0221464 denotes rterial
T169 417-424 C1704787 denotes ertain
T170 634-649 C0333482 denotes therosclerotic
T171 625-633 C2349975 denotes nhanced
T172 650-656 C0221198 denotes esion
T173 503-508 C0205394 denotes ther
T174 2928-908 C0871261 denotes
T175 2928-908 C1280519 denotes
T176 2928-908 C1527149 denotes
T177 2928-908 C1879547 denotes
T178 2928-908 C0033414 denotes
T179 326-334 C0205369 denotes pecific

PubmedHPO

Id Subject Object Predicate Lexical cue
T3 727-748 HP_0001658 denotes myocardial infarction
T2 240-250 HP_0002960 denotes autoimmune
T1 202-217 HP_0002621 denotes atherosclerosis