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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-106 Sentence denotes Signal transduction pathways activated in endothelial cells following infection with Chlamydia pneumoniae.
T2 107-165 Sentence denotes Chlamydia pneumoniae is an important respiratory pathogen.
T3 166-238 Sentence denotes Recently, its presence has been demonstrated in atherosclerotic lesions.
T4 239-501 Sentence denotes In this study, we characterized C. pneumoniae-mediated activation of endothelial cells and demonstrated an enhanced expression of endothelial adhesion molecules followed by subsequent rolling, adhesion, and transmigration of leukocytes (monocytes, granulocytes).
T5 502-621 Sentence denotes These effects were blocked by mAbs against endothelial and/or leukocyte adhesion molecules (beta1 and beta2 integrins).
T6 622-917 Sentence denotes Additionally, activation of different signal transduction pathways in C. pneumoniae-infected endothelial cells was shown: protein tyrosine phosphorylation, up-regulation of phosphorylated p42/p44 mitogen-activated protein kinase, and NF-kappaB activation/translocation occurred within 10-15 min.
T7 918-1014 Sentence denotes Increased mRNA and surface expression of E-selectin, ICAM-1, and VCAM-1 were noted within hours.
T8 1015-1196 Sentence denotes Thus, C. pneumoniae triggers a cascade of events that could lead to endothelial activation, inflammation, and thrombosis, which in turn may result in or may promote atherosclerosis.
T1 0-106 Sentence denotes Signal transduction pathways activated in endothelial cells following infection with Chlamydia pneumoniae.
T2 107-165 Sentence denotes Chlamydia pneumoniae is an important respiratory pathogen.
T3 166-238 Sentence denotes Recently, its presence has been demonstrated in atherosclerotic lesions.
T4 239-501 Sentence denotes In this study, we characterized C. pneumoniae-mediated activation of endothelial cells and demonstrated an enhanced expression of endothelial adhesion molecules followed by subsequent rolling, adhesion, and transmigration of leukocytes (monocytes, granulocytes).
T5 502-621 Sentence denotes These effects were blocked by mAbs against endothelial and/or leukocyte adhesion molecules (beta1 and beta2 integrins).
T6 622-917 Sentence denotes Additionally, activation of different signal transduction pathways in C. pneumoniae-infected endothelial cells was shown: protein tyrosine phosphorylation, up-regulation of phosphorylated p42/p44 mitogen-activated protein kinase, and NF-kappaB activation/translocation occurred within 10-15 min.
T7 918-1014 Sentence denotes Increased mRNA and surface expression of E-selectin, ICAM-1, and VCAM-1 were noted within hours.
T8 1015-1196 Sentence denotes Thus, C. pneumoniae triggers a cascade of events that could lead to endothelial activation, inflammation, and thrombosis, which in turn may result in or may promote atherosclerosis.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 42-59 cell_type denotes endothelial cells
T2 308-325 cell_type denotes endothelial cells
T3 369-399 protein denotes endothelial adhesion molecules
T4 464-474 cell_type denotes leukocytes
T5 476-485 cell_type denotes monocytes
T6 487-499 cell_type denotes granulocytes
T7 532-536 protein denotes mAbs
T8 545-592 protein denotes endothelial and/or leukocyte adhesion molecules
T9 594-619 protein denotes beta1 and beta2 integrins
T10 692-732 cell_type denotes C. pneumoniae-infected endothelial cells
T11 810-850 protein denotes p42/p44 mitogen-activated protein kinase
T12 856-865 protein denotes NF-kappaB
T13 928-932 RNA denotes mRNA
T14 959-969 protein denotes E-selectin
T15 971-977 protein denotes ICAM-1
T16 983-989 protein denotes VCAM-1

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-106 Sentence denotes Signal transduction pathways activated in endothelial cells following infection with Chlamydia pneumoniae.
S2 107-165 Sentence denotes Chlamydia pneumoniae is an important respiratory pathogen.
S3 166-238 Sentence denotes Recently, its presence has been demonstrated in atherosclerotic lesions.
S4 239-501 Sentence denotes In this study, we characterized C. pneumoniae-mediated activation of endothelial cells and demonstrated an enhanced expression of endothelial adhesion molecules followed by subsequent rolling, adhesion, and transmigration of leukocytes (monocytes, granulocytes).
S5 502-621 Sentence denotes These effects were blocked by mAbs against endothelial and/or leukocyte adhesion molecules (beta1 and beta2 integrins).
S6 622-917 Sentence denotes Additionally, activation of different signal transduction pathways in C. pneumoniae-infected endothelial cells was shown: protein tyrosine phosphorylation, up-regulation of phosphorylated p42/p44 mitogen-activated protein kinase, and NF-kappaB activation/translocation occurred within 10-15 min.
S7 918-1014 Sentence denotes Increased mRNA and surface expression of E-selectin, ICAM-1, and VCAM-1 were noted within hours.
S8 1015-1196 Sentence denotes Thus, C. pneumoniae triggers a cascade of events that could lead to endothelial activation, inflammation, and thrombosis, which in turn may result in or may promote atherosclerosis.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 42-59 NP denotes endothelial cells
C2 85-105 NP denotes Chlamydia pneumoniae
C3 107-127 NP denotes Chlamydia pneumoniae
C4 176-179 NP denotes its
C5 308-325 NP denotes endothelial cells
C6 1021-1034 NP denotes C. pneumoniae
C7 1057-1063 NP denotes events
C8 1064-1068 NP denotes that
C9 1083-1135 NP denotes endothelial activation, inflammation, and thrombosis
C10 1137-1142 NP denotes which
R1 C3 C2 coref-ident Chlamydia pneumoniae,Chlamydia pneumoniae
R2 C4 C3 coref-pron its,Chlamydia pneumoniae
R3 C5 C1 coref-ident endothelial cells,endothelial cells
R4 C6 C3 coref-ident C. pneumoniae,Chlamydia pneumoniae
R5 C8 C7 coref-relat that,events
R6 C10 C9 coref-relat which,"endothelial activation, inflammation, and thrombosis"

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-28 other_name denotes Signal transduction pathways
T2 42-59 cell_type denotes endothelial cells
T3 85-105 mono_cell denotes Chlamydia pneumoniae
T4 107-127 mono_cell denotes Chlamydia pneumoniae
T5 144-164 mono_cell denotes respiratory pathogen
T6 214-237 tissue denotes atherosclerotic lesions
T7 274-304 other_name denotes pneumoniae-mediated activation
T8 308-325 cell_type denotes endothelial cells
T9 369-399 protein_family_or_group denotes endothelial adhesion molecules
T10 464-474 cell_type denotes leukocytes
T11 476-485 cell_type denotes monocytes
T12 487-499 cell_type denotes granulocytes
T13 532-536 protein_family_or_group denotes mAbs
T14 692-705 mono_cell denotes C. pneumoniae
T15 715-732 cell_type denotes endothelial cells
T16 744-751 other_name denotes protein
T17 752-760 amino_acid_monomer denotes tyrosine
T18 810-850 protein_molecule denotes p42/p44 mitogen-activated protein kinase
T19 856-865 protein_complex denotes NF-kappaB
T20 928-932 RNA_family_or_group denotes mRNA
T21 959-969 protein_molecule denotes E-selectin
T22 971-977 protein_molecule denotes ICAM-1
T23 983-989 protein_molecule denotes VCAM-1
T24 1021-1034 mono_cell denotes C. pneumoniae
T25 1107-1119 other_name denotes inflammation
T26 1125-1135 other_name denotes thrombosis
T27 1180-1195 other_name denotes atherosclerosis

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 274-284 HP_0002090 denotes pneumoniae
T2 695-705 HP_0002090 denotes pneumoniae
T3 1180-1195 HP_0002621 denotes atherosclerosis