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PubMed:10192446 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 57-71 protein denotes erythropoietin
T2 114-124 cell_line denotes UT-7 cells
T3 310-324 cell_line denotes UT-7 cell line
T4 451-454 protein denotes Epo
T5 546-549 protein denotes Epo
T6 662-672 cell_line denotes UT-7 cells
T7 674-677 protein denotes Epo
T8 811-817 protein denotes GATA-2
T9 822-827 protein denotes c-myb
T10 851-854 protein denotes Epo
T11 860-866 protein denotes GATA-2
T12 923-926 protein denotes SCL
T13 958-961 protein denotes Epo
T14 1009-1012 protein denotes Epo
T15 1083-1096 protein denotes glycophorin A
T16 1098-1101 protein denotes GPA
T17 1120-1142 protein denotes beta- and gamma-globin
T18 1215-1227 protein denotes alpha-globin
T19 1260-1263 protein denotes Epo
T20 1272-1283 protein denotes beta-globin
T21 1405-1415 cell_line denotes UT-7 cells
T22 1446-1494 protein denotes erythroid-specific aminolaevulinic acid synthase
T23 1496-1502 protein denotes ALAS-E
T24 1575-1599 cell_line denotes multipotential cell line

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-125 Sentence denotes Erythroid gene expression is differentially regulated by erythropoietin, haemin and delta-aminolaevulinic acid in UT-7 cells.
S2 126-305 Sentence denotes Erythropoietin (Epo) is essential for the later stages of erythropoiesis, acting to promote cell survival and proliferation, but its role in differentiation remains to be defined.
S3 306-513 Sentence denotes The UT-7 cell line exhibits both erythroid and megakaryocytic characteristics and can be induced to differentiate along the erythroid pathway by Epo or the megakaryocytic pathway by phorbol myristic acetate.
S4 514-673 Sentence denotes We have compared the effects of Epo and the chemical inducers, delta-aminolaevulinic acid (delta-ALA) and haemin on the differentiation capacity of UT-7 cells.
S5 674-810 Sentence denotes Epo alone promoted relatively early events in erythroid maturation, without significant changes in haemoglobin production or morphology.
S6 811-910 Sentence denotes GATA-2 and c-myb were down-regulated by Epo, and GATA-2 was further down-modulated by the inducers.
S7 911-1008 Sentence denotes Conversely, SCL expression was up-regulated by Epo and further increased by haemin and delta-ALA.
S8 1009-1159 Sentence denotes Epo caused an increase in the proportion of cells expressing cell surface glycophorin A (GPA) and up-regulated beta- and gamma-globin by several fold.
S9 1160-1351 Sentence denotes Both haemin and delta-ALA caused a de novo increase in alpha-globin expression as well as enhancing Epo-induced beta-globin expression, leading to a marked increase in haemoglobin production.
S10 1352-1600 Sentence denotes These results suggest that haemoglobin production in UT-7 cells is limited by a deficiency of erythroid-specific aminolaevulinic acid synthase (ALAS-E) activity or globin synthesis as a consequence of their immaturity as a multipotential cell line.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 57-71 NP denotes erythropoietin
C2 73-79 NP denotes haemin
C3 84-110 NP denotes delta-aminolaevulinic acid
C4 114-124 NP denotes UT-7 cells
C5 126-146 NP denotes Erythropoietin (Epo)
C6 255-258 NP denotes its
C7 451-454 NP denotes Epo
C8 546-549 NP denotes Epo
C10 577-615 NP denotes delta-aminolaevulinic acid (delta-ALA)
C11 620-626 NP denotes haemin
C9 577-626 NP denotes delta-aminolaevulinic acid (delta-ALA) and haemin
C12 662-672 NP denotes UT-7 cells
C13 674-683 NP denotes Epo alone
C14 773-795 NP denotes haemoglobin production
C15 811-817 NP denotes GATA-2
C16 851-854 NP denotes Epo
C17 860-866 NP denotes GATA-2
C18 958-961 NP denotes Epo
C20 987-993 NP denotes haemin
C21 998-1007 NP denotes delta-ALA
C19 987-1007 NP denotes haemin and delta-ALA
C22 1009-1012 NP denotes Epo
C23 1160-1185 NP denotes Both haemin and delta-ALA
C24 1328-1350 NP denotes haemoglobin production
C25 1405-1415 NP denotes UT-7 cells
C26 1553-1558 NP denotes their
R1 C5 C1 coref-ident Erythropoietin (Epo),erythropoietin
R2 C6 C5 coref-pron its,Erythropoietin (Epo)
R3 C7 C5 coref-ident Epo,Erythropoietin (Epo)
R4 C8 C7 coref-ident Epo,Epo
R5 C10 C3 coref-ident delta-aminolaevulinic acid (delta-ALA),delta-aminolaevulinic acid
R6 C11 C2 coref-ident haemin,haemin
R7 C12 C4 coref-ident UT-7 cells,UT-7 cells
R8 C13 C8 coref-ident Epo alone,Epo
R9 C16 C13 coref-ident Epo,Epo alone
R10 C17 C15 coref-ident GATA-2,GATA-2
R11 C18 C16 coref-ident Epo,Epo
R12 C20 C11 coref-ident haemin,haemin
R13 C21 C10 coref-ident delta-ALA,delta-aminolaevulinic acid (delta-ALA)
R14 C19 C9 coref-ident haemin and delta-ALA,delta-aminolaevulinic acid (delta-ALA) and haemin
R15 C22 C18 coref-ident Epo,Epo
R16 C23 C19 coref-ident Both haemin and delta-ALA,haemin and delta-ALA
R17 C24 C14 coref-ident haemoglobin production,haemoglobin production
R18 C25 C12 coref-ident UT-7 cells,UT-7 cells
R19 C26 C25 coref-pron their,UT-7 cells

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-25 other_name denotes Erythroid gene expression
T2 57-71 protein_molecule denotes erythropoietin
T3 73-79 other_organic_compound denotes haemin
T4 84-110 other_organic_compound denotes delta-aminolaevulinic acid
T5 114-124 cell_line denotes UT-7 cells
T6 184-198 other_name denotes erythropoiesis
T7 310-324 cell_line denotes UT-7 cell line
T8 451-454 protein_family_or_group denotes Epo
T9 488-512 other_organic_compound denotes phorbol myristic acetate
T10 546-549 protein_family_or_group denotes Epo
T11 577-603 other_organic_compound denotes delta-aminolaevulinic acid
T12 620-626 other_organic_compound denotes haemin
T13 634-658 other_name denotes differentiation capacity
T14 662-672 cell_line denotes UT-7 cells
T15 674-677 protein_family_or_group denotes Epo
T16 720-740 other_name denotes erythroid maturation
T17 773-795 other_name denotes haemoglobin production
T18 811-817 protein_molecule denotes GATA-2
T19 822-827 protein_molecule denotes c-myb
T20 851-854 protein_family_or_group denotes Epo
T21 860-866 protein_molecule denotes GATA-2
T22 923-926 protein_molecule denotes SCL
T23 958-961 protein_family_or_group denotes Epo
T24 987-993 other_organic_compound denotes haemin
T25 998-1007 other_organic_compound denotes delta-ALA
T26 1009-1012 protein_family_or_group denotes Epo
T27 1083-1096 protein_molecule denotes glycophorin A
T28 1098-1101 protein_molecule denotes GPA
T29 1165-1171 other_organic_compound denotes haemin
T30 1176-1185 other_organic_compound denotes delta-ALA
T31 1215-1227 protein_molecule denotes alpha-globin
T32 1260-1263 protein_family_or_group denotes Epo
T33 1272-1283 protein_molecule denotes beta-globin
T34 1328-1350 other_name denotes haemoglobin production
T35 1379-1401 other_name denotes haemoglobin production
T36 1405-1415 cell_line denotes UT-7 cells
T37 1446-1494 protein_molecule denotes erythroid-specific aminolaevulinic acid synthase
T38 1496-1502 protein_molecule denotes ALAS-E
T39 1575-1599 cell_line denotes multipotential cell line