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PubMed:10102791 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 120-142 protein denotes NF-kappa B-like factor
T2 146-155 cell_type denotes human PMN
T3 172-216 protein denotes glycosphingolipid beta-(1,3)-glucan receptor
T4 603-641 cell_type denotes subsequently isolated blood leukocytes
T5 789-797 protein denotes cytokine
T6 942-985 protein denotes NF-kappaB-like nuclear transcription factor
T7 989-1015 cell_type denotes purified human neutrophils
T8 1170-1189 protein denotes monoclonal antibody
T9 1279-1300 protein denotes NF-kappaB-like factor
T10 1580-1597 cell_type denotes human neutrophils

semrep-sample

Id Subject Object Predicate Lexical cue
E1-ti-1 0-10 cui:C0646856 denotes PGG-glucan
E2-ti-1 33-39 cui:C0017696 denotes glucan
E3-ti-1 54-69 cui:C0085416 denotes oxidative burst
E4-ti-1 70-78 cui:C0871261 denotes response
E5-ti-1 80-92 cui:C1136254 denotes microbicidal
E6-ti-1 93-101 cui:C0439167 denotes activity
E7-ti-1 120-130 cui:C0079904 denotes NF-kappa B
E8-ti-1 136-142 cui:C1521761 denotes factor
E9-ti-1 146-151 cui:C0020114 denotes human
E10-ti-1 152-155 cui:C1526952 denotes PMN
E11-ti-1 172-189 cui:C0017978 denotes glycosphingolipid
E12-ti-1 201-207 cui:C0017696 denotes glucan
E13-ti-1 208-216 cui:C0597357 denotes receptor
T1 107-116 STIMULATES denotes activates
E1-ab-1 218-228 cui:C0646856 denotes PGG-Glucan
E2-ab-1 251-259 cui:C0205384 denotes branched
E3-ab-1 278-285 cui:C0017725 denotes glucose
E4-ab-1 286-297 cui:C1537022 denotes homopolymer
E5-ab-1 315-324 cui:C0007623 denotes cell wall
E6-ab-1 332-337 cui:C0036025 denotes yeast
E7-ab-1 338-362 cui:C0036025 denotes Saccharomyces cerevisiae
E8-ab-1 370-385 cui:C1527392 denotes immunomodulator
E9-ab-1 401-410 cui:C0023516 denotes leukocyte
E10-ab-1 411-425 cui:C0003204 denotes anti-infective
E11-ab-1 426-434 cui:C0439167 denotes activity
E12-ab-1 448-455 cui:C0439677 denotes myeloid
E13-ab-1 460-498 cui:C1513082 denotes megakaryocyte progenitor proliferation
T2 306-310 LOCATION_OF denotes from
T3 325-327 PART_OF denotes of
T4 392-400 STIMULATES denotes enhances
E1-ab-2 514-519 cui:C0020114 denotes human
E2-ab-2 520-531 cui:C0370231 denotes whole blood
E3-ab-2 537-547 cui:C0646856 denotes PGG-Glucan
E4-ab-2 575-590 cui:C0085416 denotes oxidative burst
E5-ab-2 591-599 cui:C0871261 denotes response
E6-ab-2 616-624 cui:C0205409 denotes isolated
E7-ab-2 625-641 cui:C0023516 denotes blood leukocytes
E8-ab-2 662-673 cui:C0457784 denotes particulate
E9-ab-2 690-704 cui:C1512045 denotes dose-dependent
E10-ab-2 717-726 cui:C0205217 denotes increased
E11-ab-2 727-736 cui:C0023516 denotes leukocyte
E12-ab-2 737-749 cui:C1136254 denotes microbicidal
E13-ab-2 750-758 cui:C0439167 denotes activity
E1-ab-3 776-788 cui:C0333348 denotes inflammatory
E2-ab-3 789-808 cui:C1155099 denotes cytokine production
E3-ab-3 834-844 cui:C0348080 denotes conditions
E1-ab-4 846-883 cui:C0949632 denotes Electrophoretic mobility shift assays
E2-ab-4 902-912 cui:C0646856 denotes PGG-Glucan
E3-ab-4 942-951 cui:C0079904 denotes NF-kappaB
E4-ab-4 957-964 cui:C0521447 denotes nuclear
E5-ab-4 965-985 cui:C0040648 denotes transcription factor
E6-ab-4 998-1003 cui:C0020114 denotes human
E7-ab-4 1004-1015 cui:C0027950 denotes neutrophils
T5 998-1015 PART_OF denotes human neutrophils
T6 986-988 LOCATION_OF denotes in
E1-ab-5 1035-1045 cui:C0646856 denotes PGG-Glucan
E2-ab-5 1049-1054 cui:C0020114 denotes human
E3-ab-5 1055-1064 cui:C0023516 denotes leukocyte
E4-ab-5 1065-1074 cui:C0025255 denotes membranes
E5-ab-5 1129-1133 cui:C0205250 denotes high
E6-ab-5 1147-1160 cui:C0332232 denotes approximately
E1-ab-6 1170-1189 cui:C0003250 denotes monoclonal antibody
E2-ab-6 1206-1223 cui:C0017978 denotes glycosphingolipid
E3-ab-6 1224-1240 cui:C0383881 denotes lactosylceramide
E4-ab-6 1245-1249 cui:C1299581 denotes able
E5-ab-6 1279-1288 cui:C0214222 denotes NF-kappaB
E6-ab-6 1294-1300 cui:C1521761 denotes factor
E7-ab-6 1304-1314 cui:C0646856 denotes PGG-Glucan
E8-ab-6 1320-1334 cui:C1517880 denotes ligand binding
E9-ab-6 1335-1339 cui:C1511726 denotes data
E10-ab-6 1351-1365 cui:C0032594 denotes polysaccharide
E11-ab-6 1366-1377 cui:C0037791 denotes specificity
E12-ab-6 1398-1408 cui:C0646856 denotes PGG-Glucan
E13-ab-6 1428-1444 cui:C0383881 denotes lactosylceramide
T7 1206-1240 ISA denotes glycosphingolipid lactosylceramide
T8 1261-1271 STIMULATES denotes activation
T9 1366-1377 INTERACTS_WITH denotes specificity
E1-ab-7 1452-1459 cui:C1274040 denotes results
E2-ab-7 1474-1484 cui:C0646856 denotes PGG-Glucan
E3-ab-7 1494-1504 cui:C0027950 denotes neutrophil
E4-ab-7 1510-1519 cui:C0599840 denotes microbial
E5-ab-7 1520-1529 cui:C0542341 denotes functions
E6-ab-7 1539-1550 cui:C0687133 denotes interaction
E7-ab-7 1564-1575 cui:C1134651 denotes beta-glucan
E8-ab-7 1580-1585 cui:C0020114 denotes human
E9-ab-7 1586-1597 cui:C0027950 denotes neutrophils
E10-ab-7 1617-1634 cui:C0017978 denotes glycosphingolipid
E11-ab-7 1635-1651 cui:C0383881 denotes lactosylceramide
E12-ab-7 1652-1659 cui:C0150312 denotes present
E13-ab-7 1667-1679 cui:C0699040 denotes cell surface
T10 1580-1597 PART_OF denotes human neutrophils
T11 1660-1662 LOCATION_OF denotes at
R1 E5-ti-1 T1 subjectOf microbicidal,activates
R2 E7-ti-1 T1 objectOf NF-kappa B,activates
R3 E5-ab-1 T2 subjectOf cell wall,from
R4 E4-ab-1 T2 objectOf homopolymer,from
R5 E5-ab-1 T3 subjectOf cell wall,of
R6 E7-ab-1 T3 objectOf Saccharomyces cerevisiae,of
R7 E8-ab-1 T4 subjectOf immunomodulator,enhances
R8 E10-ab-1 T4 objectOf anti-infective,enhances
R9 E7-ab-4 T5 subjectOf neutrophils,human neutrophils
R10 E6-ab-4 T5 objectOf human,human neutrophils
R11 E7-ab-4 T6 subjectOf neutrophils,in
R12 E5-ab-4 T6 objectOf transcription factor,in
R13 E3-ab-6 T7 subjectOf lactosylceramide,glycosphingolipid lactosylceramide
R14 E2-ab-6 T7 objectOf glycosphingolipid,glycosphingolipid lactosylceramide
R15 E7-ab-6 T8 subjectOf PGG-Glucan,activation
R16 E5-ab-6 T8 objectOf NF-kappaB,activation
R17 E3-ab-6 T9 subjectOf lactosylceramide,specificity
R18 E10-ab-6 T9 objectOf polysaccharide,specificity
R19 E9-ab-7 T10 subjectOf neutrophils,human neutrophils
R20 E8-ab-7 T10 objectOf human,human neutrophils
R21 E13-ab-7 T11 subjectOf cell surface,at
R22 E7-ab-7 T11 objectOf beta-glucan,at

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-217 Sentence denotes PGG-glucan, a soluble beta-(1,3)-glucan, enhances the oxidative burst response, microbicidal activity, and activates an NF-kappa B-like factor in human PMN: evidence for a glycosphingolipid beta-(1,3)-glucan receptor.
S2 218-499 Sentence denotes PGG-Glucan, a soluble beta-(1,6)-branched beta-(1,3)-linked glucose homopolymer derived from the cell wall of the yeast Saccharomyces cerevisiae, is an immunomodulator which enhances leukocyte anti-infective activity and enhances myeloid and megakaryocyte progenitor proliferation.
S3 500-759 Sentence denotes Incubation of human whole blood with PGG-Glucan significantly enhanced the oxidative burst response of subsequently isolated blood leukocytes to both soluble and particulate activators in a dose-dependent manner, and increased leukocyte microbicidal activity.
S4 760-845 Sentence denotes No evidence for inflammatory cytokine production was obtained under these conditions.
S5 846-1016 Sentence denotes Electrophoretic mobility shift assays demonstrated that PGG-Glucan induced the activation of an NF-kappaB-like nuclear transcription factor in purified human neutrophils.
S6 1017-1167 Sentence denotes The binding of 3H-PGG-Glucan to human leukocyte membranes was specific, concentration-dependent, saturable, and high affinity (Kd approximately 6 nM).
S7 1168-1445 Sentence denotes A monoclonal antibody specific to the glycosphingolipid lactosylceramide was able to inhibit activation of the NF-kappaB-like factor by PGG-Glucan, and ligand binding data, including polysaccharide specificity, suggested that the PGG-Glucan binding moiety was lactosylceramide.
S8 1446-1680 Sentence denotes These results indicate that PGG-Glucan enhances neutrophil anti-microbial functions and that interaction between this beta-glucan and human neutrophils is mediated by the glycosphingolipid lactosylceramide present at the cell surface.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-10 NP denotes PGG-glucan
C2 12-39 NP denotes a soluble beta-(1,3)-glucan
C3 120-142 NP denotes NF-kappa B-like factor
C4 218-228 NP denotes PGG-Glucan
C5 230-362 NP denotes a soluble beta-(1,6)-branched beta-(1,3)-linked glucose homopolymer derived from the cell wall of the yeast Saccharomyces cerevisiae
C6 367-385 NP denotes an immunomodulator
C7 386-391 NP denotes which
C8 537-547 NP denotes PGG-Glucan
C9 902-912 NP denotes PGG-Glucan
C10 1275-1300 NP denotes the NF-kappaB-like factor
C11 1304-1314 NP denotes PGG-Glucan
C12 1474-1484 NP denotes PGG-Glucan
C13 1559-1575 NP denotes this beta-glucan
R1 C2 C1 coref-appos "a soluble beta-(1,3)-glucan",PGG-glucan
R2 C4 C1 coref-ident PGG-Glucan,PGG-glucan
R3 C5 C4 coref-appos "a soluble beta-(1,6)-branched beta-(1,3)-linked glucose homopolymer derived from the cell wall of the yeast Saccharomyces cerevisiae",PGG-Glucan
R4 C7 C6 coref-relat which,an immunomodulator
R5 C8 C4 coref-ident PGG-Glucan,PGG-Glucan
R6 C9 C8 coref-ident PGG-Glucan,PGG-Glucan
R7 C10 C3 coref-ident the NF-kappaB-like factor,NF-kappa B-like factor
R8 C11 C9 coref-ident PGG-Glucan,PGG-Glucan
R9 C12 C11 coref-ident PGG-Glucan,PGG-Glucan
R10 C13 C12 coref-ident this beta-glucan,PGG-Glucan

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 14-39 carbohydrate denotes soluble beta-(1,3)-glucan
T2 54-78 other_name denotes oxidative burst response
T3 80-101 other_name denotes microbicidal activity
T4 120-130 protein_complex denotes NF-kappa B
T5 146-155 cell_type denotes human PMN
T6 172-207 carbohydrate denotes glycosphingolipid beta-(1,3)-glucan
T7 218-228 carbohydrate denotes PGG-Glucan
T8 232-297 carbohydrate denotes soluble beta-(1,6)-branched beta-(1,3)-linked glucose homopolymer
T9 315-324 cell_component denotes cell wall
T10 332-337 mono_cell denotes yeast
T11 338-362 mono_cell denotes Saccharomyces cerevisiae
T12 370-385 other_name denotes immunomodulator
T13 401-434 other_name denotes leukocyte anti-infective activity
T14 514-531 tissue denotes human whole blood
T15 537-547 carbohydrate denotes PGG-Glucan
T16 575-599 other_name denotes oxidative burst response
T17 603-641 cell_type denotes subsequently isolated blood leukocytes
T18 690-711 other_name denotes dose-dependent manner
T19 727-736 other_name denotes leukocyte
T20 737-758 other_name denotes microbicidal activity
T21 776-788 other_name denotes inflammatory
T22 789-797 protein_family_or_group denotes cytokine
T23 846-883 other_name denotes Electrophoretic mobility shift assays
T24 902-912 carbohydrate denotes PGG-Glucan
T25 942-951 protein_complex denotes NF-kappaB
T26 989-1015 cell_type denotes purified human neutrophils
T27 1033-1035 carbohydrate denotes H-
T28 1035-1045 carbohydrate denotes PGG-Glucan
T29 1049-1074 cell_component denotes human leukocyte membranes
T30 1170-1189 protein_family_or_group denotes monoclonal antibody
T31 1206-1223 lipid denotes glycosphingolipid
T32 1224-1240 lipid denotes lactosylceramide
T33 1279-1288 protein_complex denotes NF-kappaB
T34 1304-1314 carbohydrate denotes PGG-Glucan
T35 1351-1365 carbohydrate denotes polysaccharide
T36 1398-1408 carbohydrate denotes PGG-Glucan
T37 1428-1444 lipid denotes lactosylceramide
T38 1474-1484 carbohydrate denotes PGG-Glucan
T39 1494-1529 other_name denotes neutrophil anti-microbial functions
T40 1564-1575 carbohydrate denotes beta-glucan
T41 1580-1597 cell_type denotes human neutrophils
T42 1617-1634 lipid denotes glycosphingolipid
T43 1635-1651 lipid denotes lactosylceramide
T44 1667-1679 cell_component denotes cell surface

metamap-sample

Id Subject Object Predicate Lexical cue
T1 1581-1586 C0086418 denotes uman
T2 1050-1055 C0086418 denotes uman
T3 999-1004 C0086418 denotes uman
T4 515-520 C0086418 denotes uman
T5 147-152 C0086418 denotes uman
T6 1495-1505 C0027950 denotes eutrophil
T7 1587-1598 C0027950 denotes eutrophils
T8 1005-1016 C0027950 denotes eutrophils.
T9 153-156 C0027950 denotes MN:
T10 121-131 C0079904 denotes F-kappa B-
T11 1475-1485 C0646856 denotes GG-Glucan
T12 1036-1046 C0646856 denotes GG-Glucan
T13 903-912 C0646856 denotes GG-Glucan
T14 538-548 C0646856 denotes GG-Glucan
T15 220-229 C0646856 denotes G-Glucan,
T16 1-11 C0646856 denotes GG-glucan,
T17 55-70 C0085416 denotes xidative burst
T18 1618-1635 C0017978 denotes lycosphingolipid
T19 1207-1223 C0017978 denotes lycosphingolipid
T20 173-190 C0017978 denotes lycosphingolipid
T21 738-750 C1136254 denotes icrobicidal
T22 81-93 C1136254 denotes icrobicidal
T23 269-270 C2827736 denotes )
T24 1486-1494 C2349975 denotes nhances
T25 563-571 C2349975 denotes nhanced
T26 42-50 C2349975 denotes nhances
T27 1295-1301 C1521761 denotes actor
T28 137-143 C1521761 denotes actor
T29 108-117 C1515877 denotes ctivates
T30 209-217 C0597357 denotes eceptor.
T31 427-435 C1561536 denotes ctivity
T32 94-102 C1561536 denotes ctivity,
T33 651-658 C1749467 denotes oluble
T34 233-240 C1749467 denotes oluble
T35 15-22 C1749467 denotes oluble
T36 592-600 C0871261 denotes esponse
T37 71-79 C0871261 denotes esponse,
T38 764-772 C0332120 denotes vidence
T39 158-166 C0332120 denotes vidence
T40 1636-1652 C0383881 denotes actosylceramide
T41 1056-1064 C0023516 denotes eukocyte
T42 728-737 C0023516 denotes eukocyte
T43 402-411 C0023516 denotes eukocyte
T44 1171-1190 C0003250 denotes onoclonal antibody
T45 461-485 C2350245 denotes egakaryocyte progenitor
T46 339-363 C0036025 denotes accharomyces cerevisiae,
T47 371-386 C1527392 denotes mmunomodulator
T48 847-884 C0949632 denotes lectrophoretic mobility shift assays
T49 1164-1166 C0312860 denotes M)
T50 333-338 C0043392 denotes east
T51 412-426 C0003204 denotes nti-infective
T52 279-286 C0017725 denotes lucose
T53 1565-1576 C1134651 denotes eta-glucan
T54 1254-1261 C0018790 denotes nhibit
T55 966-986 C0040648 denotes ranscription factor
T56 316-325 C0007623 denotes ell wall
T57 1191-1199 C0205369 denotes pecific
T58 1080-1088 C0205369 denotes pecific,
T59 1410-1417 C1167622 denotes inding
T60 1022-1029 C1167622 denotes inding
T61 1066-1075 C0025255 denotes embranes
T62 1352-1366 C0032594 denotes olysaccharide
T63 1668-1680 C0699040 denotes ell surface.
T64 1342-1351 C0332257 denotes ncluding
T65 914-921 C0205263 denotes nduced
T66 449-456 C0439677 denotes yeloid
T67 1453-1460 C1274040 denotes esults
T68 1380-1389 C1705535 denotes uggested
T69 1246-1250 C1299581 denotes ble
T70 1130-1134 C1299351 denotes igh
T71 1135-1143 C1510827 denotes ffinity
T72 1367-1378 C1511884 denotes pecificity,
T73 1336-1340 C1511726 denotes ata,
T74 486-499 C0334094 denotes roliferation.
T75 287-297 C1537022 denotes omopolymer
T76 1521-1530 C0542341 denotes unctions
T77 814-822 C1301820 denotes btained
T78 1540-1551 C1704675 denotes nteraction
T79 1602-1610 C0127400 denotes ediated
T80 1653-1660 C0150312 denotes resent
T81 299-306 C1441547 denotes erived
T82 835-845 C0348080 denotes onditions.
T83 1321-1335 C1517880 denotes igand binding
T84 252-260 C2700384 denotes ranched
T85 475-485 C0870134 denotes rogenitor
T86 958-965 C0521447 denotes uclear
T87 990-998 C1998793 denotes urified
T88 1145-1146 C1705240 denotes d
T89 1148-1161 C0332232 denotes pproximately
T90 1090-1103 C1446561 denotes oncentration-
T91 1104-1113 C0851827 denotes ependent,
T92 1511-1520 C0599840 denotes icrobial
T93 272-278 C1517892 denotes inked
T94 790-809 C1327413 denotes ytokine production
T95 691-705 C1512045 denotes ose-dependent
T96 1033-1035 C1442460 denotes H-
T97 777-789 C0333348 denotes nflammatory
T98 761-762 C1298908 denotes o
T99 663-674 C0457784 denotes articulate
T100 617-625 C0205409 denotes solated
T101 626-631 C0229664 denotes lood