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PubMed:10102628 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 14-26 protein denotes IkappaBalpha
T2 45-81 cell_type denotes human peripheral blood T lymphocytes
T3 138-154 protein denotes I(kappa)B(alpha)
T4 198-220 protein denotes Rel/NF-kappaB proteins
T5 228-235 cell_type denotes cytosol
T6 246-262 protein denotes I(kappa)B(alpha)
T7 415-439 protein denotes nuclear I(kappa)B(alpha)
T8 515-551 cell_type denotes human peripheral blood T lymphocytes
T9 553-556 cell_type denotes PBL
T10 602-618 protein denotes I(kappa)B(alpha)
T11 622-625 cell_type denotes PBL
T12 740-756 protein denotes I(kappa)B(alpha)
T13 868-884 protein denotes I(kappa)B(alpha)
T14 926-942 protein denotes I(kappa)B(alpha)
T15 1038-1062 protein denotes nuclear I(kappa)B(alpha)
T16 1079-1088 protein denotes NF-kappaB
T17 1155-1166 protein denotes IkappaBbeta
T18 1274-1290 protein denotes I(kappa)B(alpha)
T19 1295-1304 protein denotes NF-kappaB
T20 1359-1382 cell_type denotes PMA-activated human PBL
T21 1384-1400 protein denotes I(kappa)B(alpha)
T22 1476-1485 protein denotes NF-kappaB

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-82 Sentence denotes Expression of IkappaBalpha in the nucleus of human peripheral blood T lymphocytes.
S2 83-236 Sentence denotes According to current models the inhibitory capacity of I(kappa)B(alpha) would be mediated through the retention of Rel/NF-kappaB proteins in the cytosol.
S3 237-364 Sentence denotes However, I(kappa)B(alpha) has also been detected in the nucleus of cell lines and when overexpressed by transient transfection.
S4 365-558 Sentence denotes To gain better insight into the potential role of nuclear I(kappa)B(alpha) in a physiological context we have analysed its presence in the nucleus of human peripheral blood T lymphocytes (PBL).
S5 559-717 Sentence denotes We demonstrate the nuclear localization of I(kappa)B(alpha) in PBL by different techniques: Western blot, indirect immunofluorescence and electron microscopy.
S6 718-847 Sentence denotes Low levels of nuclear I(kappa)B(alpha) were detected in resting cells whereas a superinduction was obtained after PMA activation.
S7 848-1007 Sentence denotes The nuclear pool of I(kappa)B(alpha) showed a higher stability than cytosolic I(kappa)B(alpha) and was partially independent of the resynthesis of the protein.
S8 1008-1188 Sentence denotes Unexpectedly, the presence of nuclear I(kappa)B(alpha) did not inhibit NF-kappaB binding to DNA and this phenomenon was not due to the presence of IkappaBbeta at the nuclear level.
S9 1189-1314 Sentence denotes Immunoprecipitation experiments failed to demonstrate an association between nuclear I(kappa)B(alpha) and NF-kappaB proteins.
S10 1315-1503 Sentence denotes Our results demonstrate that in resting and PMA-activated human PBL, I(kappa)B(alpha) is present in the nucleus in an apparently inactive form unable to disrupt NF-kappaB binding from DNA.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 14-26 NP denotes IkappaBalpha
C2 30-81 NP denotes the nucleus of human peripheral blood T lymphocytes
C3 138-154 NP denotes I(kappa)B(alpha)
C4 246-262 NP denotes I(kappa)B(alpha)
C5 415-439 NP denotes nuclear I(kappa)B(alpha)
C6 484-487 NP denotes its
C7 500-557 NP denotes the nucleus of human peripheral blood T lymphocytes (PBL)
C8 602-618 NP denotes I(kappa)B(alpha)
C9 622-625 NP denotes PBL
C10 732-756 NP denotes nuclear I(kappa)B(alpha)
C11 868-884 NP denotes I(kappa)B(alpha)
C12 995-1006 NP denotes the protein
C13 1038-1062 NP denotes nuclear I(kappa)B(alpha)
C14 1100-1103 NP denotes DNA
C15 1384-1400 NP denotes I(kappa)B(alpha)
C16 1499-1502 NP denotes DNA
R1 C3 C1 coref-ident I(kappa)B(alpha),IkappaBalpha
R2 C4 C3 coref-ident I(kappa)B(alpha),I(kappa)B(alpha)
R3 C6 C5 coref-pron its,nuclear I(kappa)B(alpha)
R4 C7 C2 coref-ident the nucleus of human peripheral blood T lymphocytes (PBL),the nucleus of human peripheral blood T lymphocytes
R5 C8 C4 coref-ident I(kappa)B(alpha),I(kappa)B(alpha)
R6 C9 C7 coref-ident PBL,the nucleus of human peripheral blood T lymphocytes (PBL)
R7 C10 C5 coref-ident nuclear I(kappa)B(alpha),nuclear I(kappa)B(alpha)
R8 C11 C8 coref-ident I(kappa)B(alpha),I(kappa)B(alpha)
R9 C12 C11 coref-ident the protein,I(kappa)B(alpha)
R10 C13 C10 coref-ident nuclear I(kappa)B(alpha),nuclear I(kappa)B(alpha)
R11 C15 C12 coref-ident I(kappa)B(alpha),the protein
R12 C16 C14 coref-ident DNA,DNA

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 14-26 protein_molecule denotes IkappaBalpha
T2 34-41 cell_component denotes nucleus
T3 45-81 cell_type denotes human peripheral blood T lymphocytes
T4 138-154 protein_molecule denotes I(kappa)B(alpha)
T5 198-220 protein_family_or_group denotes Rel/NF-kappaB proteins
T6 228-235 cell_type denotes cytosol
T7 246-262 protein_molecule denotes I(kappa)B(alpha)
T8 293-300 cell_component denotes nucleus
T9 415-422 protein_molecule denotes nuclear
T10 423-439 protein_molecule denotes I(kappa)B(alpha)
T11 504-511 cell_component denotes nucleus
T12 515-551 cell_type denotes human peripheral blood T lymphocytes
T13 553-556 cell_type denotes PBL
T14 602-618 protein_molecule denotes I(kappa)B(alpha)
T15 622-625 cell_type denotes PBL
T16 651-663 other_name denotes Western blot
T17 665-692 other_name denotes indirect immunofluorescence
T18 697-716 other_name denotes electron microscopy
T19 740-756 protein_molecule denotes I(kappa)B(alpha)
T20 798-812 other_name denotes superinduction
T21 832-846 other_name denotes PMA activation
T22 868-884 protein_molecule denotes I(kappa)B(alpha)
T23 926-942 protein_molecule denotes I(kappa)B(alpha)
T24 1038-1045 protein_molecule denotes nuclear
T25 1046-1062 protein_molecule denotes I(kappa)B(alpha)
T26 1079-1088 protein_complex denotes NF-kappaB
T27 1155-1166 protein_molecule denotes IkappaBbeta
T28 1274-1290 protein_molecule denotes I(kappa)B(alpha)
T29 1295-1304 protein_complex denotes NF-kappaB
T30 1359-1378 cell_type denotes PMA-activated human
T31 1379-1382 cell_type denotes PBL
T32 1384-1400 protein_molecule denotes I(kappa)B(alpha)
T33 1419-1426 cell_component denotes nucleus
T34 1476-1485 protein_complex denotes NF-kappaB