PubMed:1010253 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/1010253","sourcedb":"PubMed","sourceid":"1010253","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/1010253","text":"[The Holt-Oram syndrome: report of a case (author's transl)].\nSindrome di Holt-Oram. Descrizione di un caso\nA case of the Holt-Oram syndrome is described, that is, the association of a skeletal anomaly of the superior limbs, with a constant involvment of the thumbs, and an ostium secundum defect with a prolonged P-R interval. The case presented has the peculiarity of being sporadic, while from the literature a familiarity is almost constant via an autosomic dominant hereditary transmission. The more common syndromes were an alteration of the superior limbs is associated with a congenital cardiopathy are schematically underlined. Finally, the embriological reasons of this not rare association are briefly discussed.","tracks":[{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":61},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":62,"end":84},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":85,"end":107},"obj":"Sentence"},{"id":"TextSentencer_T4","span":{"begin":108,"end":327},"obj":"Sentence"},{"id":"TextSentencer_T5","span":{"begin":328,"end":495},"obj":"Sentence"},{"id":"TextSentencer_T6","span":{"begin":496,"end":636},"obj":"Sentence"},{"id":"TextSentencer_T7","span":{"begin":637,"end":723},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":61},"obj":"Sentence"},{"id":"T2","span":{"begin":62,"end":84},"obj":"Sentence"},{"id":"T3","span":{"begin":85,"end":107},"obj":"Sentence"},{"id":"T4","span":{"begin":108,"end":327},"obj":"Sentence"},{"id":"T5","span":{"begin":328,"end":495},"obj":"Sentence"},{"id":"T6","span":{"begin":496,"end":636},"obj":"Sentence"},{"id":"T7","span":{"begin":637,"end":723},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"TextSentencer_T1","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T2","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T3","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T4","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T5","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T6","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T7","pred":"source","obj":"sentences"},{"subj":"T1","pred":"source","obj":"sentences"},{"subj":"T2","pred":"source","obj":"sentences"},{"subj":"T3","pred":"source","obj":"sentences"},{"subj":"T4","pred":"source","obj":"sentences"},{"subj":"T5","pred":"source","obj":"sentences"},{"subj":"T6","pred":"source","obj":"sentences"},{"subj":"T7","pred":"source","obj":"sentences"}]},{"project":"performance-test","denotations":[{"id":"PD-UBERON-AE-B_T1","span":{"begin":218,"end":223},"obj":"http://purl.obolibrary.org/obo/UBERON_0002101"},{"id":"PD-UBERON-AE-B_T2","span":{"begin":557,"end":562},"obj":"http://purl.obolibrary.org/obo/UBERON_0002101"}],"attributes":[{"subj":"PD-UBERON-AE-B_T1","pred":"source","obj":"performance-test"},{"subj":"PD-UBERON-AE-B_T2","pred":"source","obj":"performance-test"}]},{"project":"PubCasesORDO","denotations":[{"id":"TI1","span":{"begin":5,"end":23},"obj":"ORDO:392"},{"id":"AB1","span":{"begin":122,"end":140},"obj":"ORDO:392"}],"namespaces":[{"prefix":"ORDO","uri":"http://www.orpha.net/ORDO/Orphanet_"}],"attributes":[{"subj":"TI1","pred":"source","obj":"PubCasesORDO"},{"subj":"AB1","pred":"source","obj":"PubCasesORDO"}]},{"project":"UBERON-AE","denotations":[{"id":"PD-UBERON-AE-B_T1","span":{"begin":218,"end":223},"obj":"http://purl.obolibrary.org/obo/UBERON_0002101"},{"id":"PD-UBERON-AE-B_T2","span":{"begin":557,"end":562},"obj":"http://purl.obolibrary.org/obo/UBERON_0002101"}],"attributes":[{"subj":"PD-UBERON-AE-B_T1","pred":"source","obj":"UBERON-AE"},{"subj":"PD-UBERON-AE-B_T2","pred":"source","obj":"UBERON-AE"}]},{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":185,"end":201},"obj":"HP_0000924"},{"id":"T2","span":{"begin":241,"end":265},"obj":"HP_0001172"},{"id":"T3","span":{"begin":452,"end":470},"obj":"HP_0000006"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"},{"subj":"T2","pred":"source","obj":"PubmedHPO"},{"subj":"T3","pred":"source","obj":"PubmedHPO"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"sentences","color":"#ec939d","default":true},{"id":"performance-test","color":"#93b7ec"},{"id":"PubCasesORDO","color":"#d1ec93"},{"id":"UBERON-AE","color":"#ec93eb"},{"id":"PubmedHPO","color":"#93ecd2"}]}]}}