PubMed:10092606
Annnotations
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 25-29 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T3 | 170-174 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T5 | 280-284 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T7 | 395-399 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T9 | 1018-1022 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T11 | 1076-1080 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T13 | 1548-1552 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T15 | 1684-1688 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T17 | 1823-1827 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T19 | 1868-1872 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T21 | 1927-1931 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T23 | 2031-2035 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T25 | 2066-2078 | Cell | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL:0000232 |
| T26 | 2123-2135 | Cell | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL:0000232 |
GGDB-2020
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 126-157 | https://acgg.asia/db/ggdb/info/gg077 | denotes | beta1,4-galactosyltransferase I |
ggdb-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 126-157 | https://acgg.asia/db/ggdb/info/gg077 | denotes | beta1,4-galactosyltransferase I |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 30-49 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T2 | 175-194 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T3 | 232-251 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T4 | 285-304 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T5 | 400-419 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T6 | 805-824 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T7 | 985-994 | Glycan_Motif | denotes | galactose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T9 | 1023-1043 | Glycan_Motif | denotes | N-acetyllactosamines | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T10 | 1081-1100 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T11 | 1253-1272 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T12 | 1400-1419 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T13 | 1494-1503 | Glycan_Motif | denotes | galactose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T15 | 1553-1573 | Glycan_Motif | denotes | N-acetyllactosamines | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T16 | 1654-1673 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T17 | 1689-1709 | Glycan_Motif | denotes | N-acetyllactosamines | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T18 | 1828-1847 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T19 | 1873-1892 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T20 | 1932-1951 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T21 | 2036-2056 | Glycan_Motif | denotes | N-acetyllactosamines | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-60 | Sentence | denotes | Regulation of I-branched poly-N-acetyllactosamine synthesis. |
| T2 | 61-158 | Sentence | denotes | Concerted actions by I-extension enzyme, I-branching enzyme, and beta1,4-galactosyltransferase I. |
| T3 | 159-383 | Sentence | denotes | I-branched poly-N-acetyllactosamine is a unique carbohydrate composed of N-acetyllactosamine branches attached to linear poly-N-acetyllactosamine, which is synthesized by I-branching beta1, 6-N-acetylglucosaminyltransferase. |
| T4 | 384-581 | Sentence | denotes | I-branched poly-N-acetyllactosamine can carry bivalent functional oligosaccharides such as sialyl Lewisx, which provide much better carbohydrate ligands than monovalent functional oligosaccharides. |
| T5 | 582-856 | Sentence | denotes | In the present study, we first demonstrate that I-branching beta1, 6-N-acetylglucosaminyltransferase cloned from human PA-1 embryonic carcinoma cells transfers beta1,6-linked GlcNAc preferentially to galactosyl residues of N-acetyllactosamine close to nonreducing terminals. |
| T6 | 857-1044 | Sentence | denotes | We then demonstrate that among various beta1, 4-galactosyltransferases (beta4Gal-Ts), beta4Gal-TI is most efficient in adding a galactose to linear and branched poly-N-acetyllactosamines. |
| T7 | 1045-1336 | Sentence | denotes | When a beta1,6-GlcNAc branched poly-N-acetyllactosamine was incubated with a mixture of beta4Gal-TI and i-extension beta1,3-N-acetylglucosaminyltransferase, the major product was the oligosaccharide with one N-acetyllactosamine extension on the linear Galbeta1-->4GlcNAcbeta1-->3 side chain. |
| T8 | 1337-1430 | Sentence | denotes | Only a minor product contained galactosylated I-branch without N-acetyllactosamine extension. |
| T9 | 1431-1710 | Sentence | denotes | This finding was explained by the fact that beta4Gal-TI adds a galactose poorly to beta1,6-GlcNAc attached to linear poly-N-acetyllactosamines, while beta1, 3-N-acetylglucosaminyltransferase and beta4Gal-TI efficiently add N-acetyllactosamine to linear poly-N-acetyllactosamines. |
| T10 | 1711-1963 | Sentence | denotes | Together, these results strongly suggest that galactosylation of I-branch is a rate-limiting step in I-branched poly-N-acetyllactosamine synthesis, allowing poly-N-acetyllactosamine extension mostly along the linear poly-N-acetyllactosamine side chain. |
| T11 | 1964-2171 | Sentence | denotes | These findings are entirely consistent with previous findings that poly-N-acetyllactosamines in human erythrocytes, PA-1 embryonic carcinoma cells, and rabbit erythrocytes contain multiple, short I-branches. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 30-49 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T2 | 175-194 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T3 | 232-251 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T4 | 285-304 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T5 | 400-419 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T6 | 805-824 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T7 | 985-994 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactose |
| T8 | 985-994 | https://glytoucan.org/Structures/Glycans/G68158BT | denotes | galactose |
| T9 | 1023-1043 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamines |
| T10 | 1081-1100 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T11 | 1253-1272 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T12 | 1400-1419 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T13 | 1494-1503 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactose |
| T14 | 1494-1503 | https://glytoucan.org/Structures/Glycans/G68158BT | denotes | galactose |
| T15 | 1553-1573 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamines |
| T16 | 1654-1673 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T17 | 1689-1709 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamines |
| T18 | 1828-1847 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T19 | 1873-1892 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T20 | 1932-1951 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T21 | 2036-2056 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamines |
NGLY1-deficiency
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-NGLY1-deficiency-B_T1 | 757-763 | chem:24139 | denotes | GlcNAc |
| PD-NGLY1-deficiency-B_T2 | 1060-1066 | chem:24139 | denotes | GlcNAc |
| PD-NGLY1-deficiency-B_T3 | 1522-1528 | chem:24139 | denotes | GlcNAc |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 2066-2078 | HP_0001901 | denotes | erythrocytes |
| T2 | 2123-2135 | HP_0001901 | denotes | erythrocytes |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 716-725 | Phenotype | denotes | carcinoma | HP:0030731 |
| T2 | 2095-2104 | Phenotype | denotes | carcinoma | HP:0030731 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 706-725 | Disease | denotes | embryonic carcinoma | http://purl.obolibrary.org/obo/MONDO_0005440 |
| T2 | 2085-2104 | Disease | denotes | embryonic carcinoma | http://purl.obolibrary.org/obo/MONDO_0005440 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 695-700 | OrganismTaxon | denotes | human | 9606 |
| T2 | 2060-2065 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 84-93 | Body_part | denotes | extension | http://purl.obolibrary.org/obo/UBERON_2000106 |
| T2 | 1151-1160 | Body_part | denotes | extension | http://purl.obolibrary.org/obo/UBERON_2000106 |
| T3 | 1273-1282 | Body_part | denotes | extension | http://purl.obolibrary.org/obo/UBERON_2000106 |
| T4 | 1420-1429 | Body_part | denotes | extension | http://purl.obolibrary.org/obo/UBERON_2000106 |
| T5 | 1893-1902 | Body_part | denotes | extension | http://purl.obolibrary.org/obo/UBERON_2000106 |
| T6 | 2066-2078 | Body_part | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL_0000232 |
| T7 | 2123-2135 | Body_part | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL_0000232 |