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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 1194-1201 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T2 1312-1318 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 1194-1201 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T2 1312-1318 Glycan_Motif denotes fucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 1194-1201 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T2 1312-1318 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-70 Sentence denotes N-Glycosylation of a mouse IgG expressed in transgenic tobacco plants.
TextSentencer_T2 71-378 Sentence denotes Since plants are emerging as an important system for the expression of recombinant glycoproteins, especially those intended for therapeutic purposes, it is important to scrutinize to what extent glycans harbored by mammalian glycoproteins produced in transgenic plants differ from their natural counterpart.
TextSentencer_T3 379-514 Sentence denotes We report here the first detailed analysis of the glycosylation of a functional mammalian glycoprotein expressed in a transgenic plant.
TextSentencer_T4 515-766 Sentence denotes The structures of the N-linked glycans attached to the heavy chains of the monoclonal antibody Guy's 13 produced in transgenic tobacco plants (plantibody Guy's 13) were identified and compared to those found in the corresponding IgG1 of murine origin.
TextSentencer_T5 767-879 Sentence denotes Both N-glycosylation sites located on the heavy chain of the plantibody Guy's 13 are N-glycosylated as in mouse.
TextSentencer_T6 880-986 Sentence denotes However, the number of Guy's 13 glycoforms is higher in the plant than in the mammalian expression system.
TextSentencer_T7 987-1173 Sentence denotes Despite the high structural diversity of the plantibody N-glycans, glycosylation appears to be sufficient for the production of a soluble and biologically active IgG in the plant system.
TextSentencer_T8 1174-1359 Sentence denotes In addition to high-mannose-type N-glycans, 60% of the oligosaccharides N-linked to the plantibody have beta(1, 2)-xylose and alpha(1, 3)-fucose residues linked to the core Man3GlcNAc2.
TextSentencer_T9 1360-1489 Sentence denotes These plant-specific oligosaccharide structures are not a limitation to the use of plantibody Guy's 13 for topical immunotherapy.
TextSentencer_T10 1490-1590 Sentence denotes However, their immunogenicity may raise concerns for systemic applications of plantibodies in human.
T1 0-70 Sentence denotes N-Glycosylation of a mouse IgG expressed in transgenic tobacco plants.
T2 71-378 Sentence denotes Since plants are emerging as an important system for the expression of recombinant glycoproteins, especially those intended for therapeutic purposes, it is important to scrutinize to what extent glycans harbored by mammalian glycoproteins produced in transgenic plants differ from their natural counterpart.
T3 379-514 Sentence denotes We report here the first detailed analysis of the glycosylation of a functional mammalian glycoprotein expressed in a transgenic plant.
T4 515-766 Sentence denotes The structures of the N-linked glycans attached to the heavy chains of the monoclonal antibody Guy's 13 produced in transgenic tobacco plants (plantibody Guy's 13) were identified and compared to those found in the corresponding IgG1 of murine origin.
T5 767-879 Sentence denotes Both N-glycosylation sites located on the heavy chain of the plantibody Guy's 13 are N-glycosylated as in mouse.
T6 880-986 Sentence denotes However, the number of Guy's 13 glycoforms is higher in the plant than in the mammalian expression system.
T7 987-1173 Sentence denotes Despite the high structural diversity of the plantibody N-glycans, glycosylation appears to be sufficient for the production of a soluble and biologically active IgG in the plant system.
T8 1174-1359 Sentence denotes In addition to high-mannose-type N-glycans, 60% of the oligosaccharides N-linked to the plantibody have beta(1, 2)-xylose and alpha(1, 3)-fucose residues linked to the core Man3GlcNAc2.
T9 1360-1489 Sentence denotes These plant-specific oligosaccharide structures are not a limitation to the use of plantibody Guy's 13 for topical immunotherapy.
T10 1490-1590 Sentence denotes However, their immunogenicity may raise concerns for systemic applications of plantibodies in human.
T1 0-70 Sentence denotes N-Glycosylation of a mouse IgG expressed in transgenic tobacco plants.
T2 71-378 Sentence denotes Since plants are emerging as an important system for the expression of recombinant glycoproteins, especially those intended for therapeutic purposes, it is important to scrutinize to what extent glycans harbored by mammalian glycoproteins produced in transgenic plants differ from their natural counterpart.
T3 379-514 Sentence denotes We report here the first detailed analysis of the glycosylation of a functional mammalian glycoprotein expressed in a transgenic plant.
T4 515-766 Sentence denotes The structures of the N-linked glycans attached to the heavy chains of the monoclonal antibody Guy's 13 produced in transgenic tobacco plants (plantibody Guy's 13) were identified and compared to those found in the corresponding IgG1 of murine origin.
T5 767-879 Sentence denotes Both N-glycosylation sites located on the heavy chain of the plantibody Guy's 13 are N-glycosylated as in mouse.
T6 880-986 Sentence denotes However, the number of Guy's 13 glycoforms is higher in the plant than in the mammalian expression system.
T7 987-1173 Sentence denotes Despite the high structural diversity of the plantibody N-glycans, glycosylation appears to be sufficient for the production of a soluble and biologically active IgG in the plant system.
T8 1174-1359 Sentence denotes In addition to high-mannose-type N-glycans, 60% of the oligosaccharides N-linked to the plantibody have beta(1, 2)-xylose and alpha(1, 3)-fucose residues linked to the core Man3GlcNAc2.
T9 1360-1489 Sentence denotes These plant-specific oligosaccharide structures are not a limitation to the use of plantibody Guy's 13 for topical immunotherapy.
T10 1490-1590 Sentence denotes However, their immunogenicity may raise concerns for systemic applications of plantibodies in human.

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 27-30 FMAID:167179 denotes IgG
_T2 63-69 FMAID:214748 denotes plants
_T3 77-83 FMAID:214748 denotes plants
_T4 154-167 FMAID:167256 denotes glycoproteins
_T5 154-167 FMAID:62925 denotes glycoproteins
_T6 296-309 FMAID:62925 denotes glycoproteins
_T7 296-309 FMAID:167256 denotes glycoproteins
_T8 333-339 FMAID:214748 denotes plants
_T9 469-481 FMAID:62925 denotes glycoprotein
_T10 469-481 FMAID:167256 denotes glycoprotein
_T11 508-513 FMAID:214748 denotes plant
_T12 601-609 FMAID:167180 denotes antibody
_T13 650-656 FMAID:214748 denotes plants
_T14 940-945 FMAID:214748 denotes plant
_T15 1149-1152 FMAID:167179 denotes IgG
_T16 1160-1165 FMAID:214748 denotes plant
_T17 1194-1201 FMAID:196796 denotes mannose
_T18 1194-1201 FMAID:82801 denotes mannose
_T19 1229-1245 FMAID:82742 denotes oligosaccharides
_T20 1229-1245 FMAID:196731 denotes oligosaccharides
_T21 1289-1295 FMAID:196799 denotes xylose
_T22 1289-1295 FMAID:82804 denotes xylose
_T23 1312-1318 FMAID:82790 denotes fucose
_T24 1312-1318 FMAID:196784 denotes fucose
_T25 1366-1371 FMAID:214748 denotes plant
_T26 1381-1396 FMAID:82742 denotes oligosaccharide
_T27 1381-1396 FMAID:196731 denotes oligosaccharide

uniprot-human

Id Subject Object Predicate Lexical cue
T1 1278-1284 http://www.uniprot.org/uniprot/Q92988 denotes beta(1

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 590-600 http://purl.bioontology.org/ontology/NCBITAXON/608684 denotes monoclonal
T2 1278-1282 http://purl.bioontology.org/ontology/NCBITAXON/158455 denotes beta
T3 1278-1282 http://purl.bioontology.org/ontology/NCBITAXON/3554 denotes beta

GO-BP

Id Subject Object Predicate Lexical cue
T1 2-15 http://purl.obolibrary.org/obo/GO_0070085 denotes Glycosylation
T2 429-442 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T3 774-787 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T4 854-866 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylated

GO-MF

Id Subject Object Predicate Lexical cue
T1 601-609 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody

GO-CC

Id Subject Object Predicate Lexical cue
T1 744-748 http://purl.obolibrary.org/obo/GO_0071735 denotes IgG1
T2 1342-1346 http://purl.obolibrary.org/obo/GO_0019013 denotes core

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 63-69 http://edamontology.org/topic_0780 denotes plants
T2 77-83 http://edamontology.org/topic_0780 denotes plants
T3 333-339 http://edamontology.org/topic_0780 denotes plants
T4 469-491 http://edamontology.org/topic_0121 denotes glycoprotein expressed
T5 469-491 http://edamontology.org/topic_0108 denotes glycoprotein expressed
T6 508-513 http://edamontology.org/topic_0780 denotes plant
T7 650-656 http://edamontology.org/topic_0780 denotes plants
T8 940-945 http://edamontology.org/topic_0780 denotes plant
T9 1160-1165 http://edamontology.org/topic_0780 denotes plant
T10 1366-1371 http://edamontology.org/topic_0780 denotes plant
T11 1467-1474 http://edamontology.org/topic_0003 denotes topical
T12 1475-1488 http://edamontology.org/topic_3400 denotes immunotherapy
T13 1505-1519 http://edamontology.org/topic_2830 denotes immunogenicity
T14 1584-1589 http://edamontology.org/topic_2815 denotes human

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 382-388 http://edamontology.org/data_2048 denotes report
T2 413-421 http://edamontology.org/operation_2945 denotes analysis
T3 519-529 http://edamontology.org/data_0883 denotes structures
T4 684-694 http://edamontology.org/data_2611 denotes identified
T5 684-694 http://edamontology.org/data_0842 denotes identified
T6 1004-1014 http://edamontology.org/data_0883 denotes structural
T7 1319-1327 http://edamontology.org/data_1756 denotes residues
T8 1397-1407 http://edamontology.org/data_0883 denotes structures

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 1043-1052 http://rdf.glycoinfo.org/glycan/G00027MO denotes N-glycans
T2 1207-1216 http://rdf.glycoinfo.org/glycan/G00027MO denotes N-glycans
T3 1189-1201 http://rdf.glycoinfo.org/glycan/G00028MO denotes high-mannose

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 21-26 OrganismTaxon denotes mouse 10088|10090
T3 55-62 OrganismTaxon denotes tobacco 4097
T4 642-649 OrganismTaxon denotes tobacco 4097
T5 873-878 OrganismTaxon denotes mouse 10088|10090
T7 1584-1589 OrganismTaxon denotes human 9606