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PubMed:10080948 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 19-24 protein denotes TRAF2
T2 49-72 protein denotes CD40 cytoplasmic domain
T3 74-79 protein denotes TRAF2
T4 85-120 protein denotes signal transducing adaptor molecule
T5 140-163 protein denotes CD40 cytoplasmic domain
T6 274-283 cell_line denotes 293 cells
T7 373-378 protein denotes TRAF2
T8 498-515 protein denotes wild-type protein
T9 560-565 protein denotes TRAF2
T10 631-635 protein denotes CD40
T11 679-702 protein denotes CD40 cytoplasmic domain
T12 754-759 protein denotes TRAF2
T13 769-780 protein denotes phosphatase
T14 829-834 protein denotes TRAF2
T15 838-842 protein denotes CD40
T16 903-908 protein denotes TRAF2
T17 1011-1015 protein denotes CD40
T18 1015-1021 protein denotes -TRAF2

genia-medco-coref

Id Subject Object Predicate Lexical cue
C2 19-24 NP denotes TRAF2
C1 0-24 NP denotes Phosphorylation of TRAF2
C3 45-72 NP denotes the CD40 cytoplasmic domain
C4 74-79 NP denotes TRAF2
C5 83-120 NP denotes a signal transducing adaptor molecule
C6 121-126 NP denotes which
C7 136-163 NP denotes the CD40 cytoplasmic domain
C8 184-186 NP denotes it
C9 285-304 NP denotes The phosphorylation
C10 330-350 NP denotes the signaling events
C11 351-355 NP denotes that
C12 373-378 NP denotes TRAF2
C13 494-515 NP denotes the wild-type protein
C14 560-565 NP denotes TRAF2
C15 608-619 NP denotes the protein
C16 631-635 NP denotes CD40
C17 653-669 NP denotes our observations
C18 670-674 NP denotes that
C19 675-702 NP denotes the CD40 cytoplasmic domain
C20 764-768 NP denotes that
C21 829-834 NP denotes TRAF2
C22 838-842 NP denotes CD40
C24 903-908 NP denotes TRAF2
C23 880-908 NP denotes the phosphorylation of TRAF2
C25 982-985 NP denotes its
R1 C4 C2 coref-ident TRAF2,TRAF2
R2 C6 C5 coref-relat which,a signal transducing adaptor molecule
R3 C7 C3 coref-ident the CD40 cytoplasmic domain,the CD40 cytoplasmic domain
R4 C8 C4 coref-pron it,TRAF2
R5 C9 C1 coref-ident The phosphorylation,Phosphorylation of TRAF2
R6 C11 C10 coref-relat that,the signaling events
R7 C12 C4 coref-ident TRAF2,TRAF2
R8 C13 C12 coref-ident the wild-type protein,TRAF2
R9 C14 C13 coref-ident TRAF2,the wild-type protein
R10 C15 C14 coref-ident the protein,TRAF2
R11 C16 C7 coref-ident CD40,the CD40 cytoplasmic domain
R12 C18 C17 coref-relat that,our observations
R13 C19 C16 coref-ident the CD40 cytoplasmic domain,CD40
R14 C20 C17 coref-relat that,our observations
R15 C21 C14 coref-ident TRAF2,TRAF2
R16 C22 C19 coref-ident CD40,the CD40 cytoplasmic domain
R17 C24 C21 coref-ident TRAF2,TRAF2
R18 C23 C9 coref-ident the phosphorylation of TRAF2,The phosphorylation
R19 C25 C23 coref-pron its,the phosphorylation of TRAF2

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-73 Sentence denotes Phosphorylation of TRAF2 inhibits binding to the CD40 cytoplasmic domain.
S2 74-164 Sentence denotes TRAF2 is a signal transducing adaptor molecule which binds to the CD40 cytoplasmic domain.
S3 165-284 Sentence denotes We have found that it is phosphorylated, predominantly on serine residues, when transiently overexpressed in 293 cells.
S4 285-516 Sentence denotes The phosphorylation appears to be related to the signaling events that are activated by TRAF2 under these circumstances, since two nonfunctional mutants were found to be phosphorylated significantly less than the wild-type protein.
S5 517-843 Sentence denotes Furthermore, the phosphorylation status of TRAF2 had significant effects on the ability of the protein to bind to CD40, as evidenced by our observations that the CD40 cytoplasmic domain interacted preferentially with underphosphorylated TRAF2 and that phosphatase treatment significantly enhanced the binding of TRAF2 to CD40.
S6 844-1034 Sentence denotes We conclude from these studies that the phosphorylation of TRAF2 is likely to play an important role in regulating signaling by virtue of its ability to influence the CD40-TRAF2 interaction.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 19-24 protein_molecule denotes TRAF2
T2 49-72 protein_domain_or_region denotes CD40 cytoplasmic domain
T3 74-79 protein_molecule denotes TRAF2
T4 85-120 protein_family_or_group denotes signal transducing adaptor molecule
T5 140-163 protein_domain_or_region denotes CD40 cytoplasmic domain
T6 223-229 amino_acid_monomer denotes serine
T7 274-283 cell_line denotes 293 cells
T8 373-378 protein_molecule denotes TRAF2
T9 498-515 protein_family_or_group denotes wild-type protein
T10 534-556 other_name denotes phosphorylation status
T11 560-565 protein_molecule denotes TRAF2
T12 631-635 protein_molecule denotes CD40
T13 679-683 protein_molecule denotes CD40
T14 754-759 protein_molecule denotes TRAF2
T15 769-780 protein_family_or_group denotes phosphatase
T16 829-834 protein_molecule denotes TRAF2
T17 838-842 protein_molecule denotes CD40
T18 884-899 other_name denotes phosphorylation
T19 903-908 protein_molecule denotes TRAF2
T20 1011-1015 protein_molecule denotes CD40
T21 1015-1021 protein_molecule denotes -TRAF2