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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-103 Sentence denotes Nuclear factor-kappa B activity in T cells from patients with rheumatic diseases: a preliminary report.
T2 104-114 Sentence denotes OBJECTIVE:
T3 115-282 Sentence denotes The NF-kappa B/Rel family of transcription factors regulates the expression of many genes involved in the immune or inflammatory response at the transcriptional level.
T4 283-421 Sentence denotes The aim of this study was to determine whether distinctive patterns of NF-kappa B activation are seen in different forms of joint disease.
T5 422-430 Sentence denotes METHODS:
T6 431-692 Sentence denotes The DNA binding activity of these nucleoproteins was examined in purified synovial and peripheral T cells from patients with various chronic rheumatic diseases (12: four with rheumatoid arthritis; five with spondyloarthropathies; and three with osteoarthritis).
T7 693-701 Sentence denotes RESULTS:
T8 702-971 Sentence denotes Electrophoretic mobility shift assays disclosed two specific complexes bound to a NF-kappa B specific 32P-labelled oligonucleotide in nucleoproteins extracted from purified T cells isolated from synovial fluid and peripheral blood of patients with rheumatoid arthritis.
T9 972-1043 Sentence denotes The complexes consisted of p50/p50 homodimers and p50/p65 heterodimers.
T10 1044-1144 Sentence denotes Increased NF-kappa B binding to DNA in synovial T cells was observed relative to peripheral T cells.
T11 1145-1263 Sentence denotes In non-rheumatoid arthritis, binding of NF-kappa B in synovial T cells was exclusively mediated by p50/p50 homodimers.
T12 1264-1275 Sentence denotes CONCLUSION:
T13 1276-1419 Sentence denotes Overall, the results suggest that NF-kappa B may play a central part in the activation of infiltrating T cells in chronic rheumatoid arthritis.
T14 1420-1620 Sentence denotes The activation of this nuclear factor is qualitatively different in rheumatoid synovial T cells to that in other forms of non-rheumatoid arthritis (for example, osteoarthritis, spondyloarthropathies).
T1 0-103 Sentence denotes Nuclear factor-kappa B activity in T cells from patients with rheumatic diseases: a preliminary report.
T2 104-114 Sentence denotes OBJECTIVE:
T3 115-282 Sentence denotes The NF-kappa B/Rel family of transcription factors regulates the expression of many genes involved in the immune or inflammatory response at the transcriptional level.
T4 283-421 Sentence denotes The aim of this study was to determine whether distinctive patterns of NF-kappa B activation are seen in different forms of joint disease.
T5 422-430 Sentence denotes METHODS:
T6 431-692 Sentence denotes The DNA binding activity of these nucleoproteins was examined in purified synovial and peripheral T cells from patients with various chronic rheumatic diseases (12: four with rheumatoid arthritis; five with spondyloarthropathies; and three with osteoarthritis).
T7 693-701 Sentence denotes RESULTS:
T8 702-971 Sentence denotes Electrophoretic mobility shift assays disclosed two specific complexes bound to a NF-kappa B specific 32P-labelled oligonucleotide in nucleoproteins extracted from purified T cells isolated from synovial fluid and peripheral blood of patients with rheumatoid arthritis.
T9 972-1043 Sentence denotes The complexes consisted of p50/p50 homodimers and p50/p65 heterodimers.
T10 1044-1144 Sentence denotes Increased NF-kappa B binding to DNA in synovial T cells was observed relative to peripheral T cells.
T11 1145-1263 Sentence denotes In non-rheumatoid arthritis, binding of NF-kappa B in synovial T cells was exclusively mediated by p50/p50 homodimers.
T12 1264-1275 Sentence denotes CONCLUSION:
T13 1276-1419 Sentence denotes Overall, the results suggest that NF-kappa B may play a central part in the activation of infiltrating T cells in chronic rheumatoid arthritis.
T14 1420-1620 Sentence denotes The activation of this nuclear factor is qualitatively different in rheumatoid synovial T cells to that in other forms of non-rheumatoid arthritis (for example, osteoarthritis, spondyloarthropathies).

PMID_GLOBAL

Id Subject Object Predicate Lexical cue mondo_id
T1 62-80 DiseaseOrPhenotypicFeature denotes rheumatic diseases 0005554
T2 407-420 DiseaseOrPhenotypicFeature denotes joint disease 0006816
T3 572-590 DiseaseOrPhenotypicFeature denotes rheumatic diseases 0005554
T4 606-626 DiseaseOrPhenotypicFeature denotes rheumatoid arthritis 0008383
T5 676-690 DiseaseOrPhenotypicFeature denotes osteoarthritis 0005178
T6 950-970 DiseaseOrPhenotypicFeature denotes rheumatoid arthritis 0008383
T7 1152-1172 DiseaseOrPhenotypicFeature denotes rheumatoid arthritis 0008383
T8 1398-1418 DiseaseOrPhenotypicFeature denotes rheumatoid arthritis 0008383
T9 1546-1566 DiseaseOrPhenotypicFeature denotes rheumatoid arthritis 0008383
T10 1581-1595 DiseaseOrPhenotypicFeature denotes osteoarthritis 0005178

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-22 protein denotes Nuclear factor-kappa B
T2 35-42 cell_type denotes T cells
T3 119-140 protein denotes NF-kappa B/Rel family
T4 144-165 protein denotes transcription factors
T5 354-364 protein denotes NF-kappa B
T6 465-479 protein denotes nucleoproteins
T7 505-536 cell_type denotes synovial and peripheral T cells
T8 784-794 protein denotes NF-kappa B
T9 836-850 protein denotes nucleoproteins
T10 866-882 cell_type denotes purified T cells
T11 976-985 protein denotes complexes
T12 999-1017 protein denotes p50/p50 homodimers
T13 1054-1064 protein denotes NF-kappa B
T14 1083-1099 cell_type denotes synovial T cells
T15 1185-1195 protein denotes NF-kappa B
T16 1199-1215 cell_type denotes synovial T cells
T17 1244-1262 protein denotes p50/p50 homodimers
T18 1310-1320 protein denotes NF-kappa B
T19 1366-1386 cell_type denotes infiltrating T cells
T20 1488-1515 cell_type denotes rheumatoid synovial T cells

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 354-375 NP denotes NF-kappa B activation
C2 999-1017 NP denotes p50/p50 homodimers
C3 1083-1099 NP denotes synovial T cells
C4 1148-1172 NP denotes non-rheumatoid arthritis
C5 1185-1195 NP denotes NF-kappa B
C6 1199-1215 NP denotes synovial T cells
C7 1244-1262 NP denotes p50/p50 homodimers
C8 1310-1320 NP denotes NF-kappa B
C10 1438-1457 NP denotes this nuclear factor
C9 1420-1457 NP denotes The activation of this nuclear factor
C11 1519-1523 NP denotes that
C12 1542-1566 NP denotes non-rheumatoid arthritis
R1 C6 C3 coref-ident synovial T cells,synovial T cells
R2 C7 C2 coref-ident p50/p50 homodimers,p50/p50 homodimers
R3 C8 C5 coref-ident NF-kappa B,NF-kappa B
R4 C10 C8 coref-ident this nuclear factor,NF-kappa B
R5 C9 C1 coref-ident The activation of this nuclear factor,NF-kappa B activation
R6 C11 C9 coref-pron that,The activation of this nuclear factor
R7 C12 C4 coref-ident non-rheumatoid arthritis,non-rheumatoid arthritis

semrep-sample

Id Subject Object Predicate Lexical cue
E1-ti-1 0-22 cui:C0079904 denotes Nuclear factor-kappa B
E2-ti-1 23-31 cui:C0439167 denotes activity
E3-ti-1 35-42 cui:C0039194 denotes T cells
E4-ti-1 48-56 cui:C0030705 denotes patients
E5-ti-1 62-80 cui:C0035435 denotes rheumatic diseases
E6-ti-1 84-95 cui:C0439611 denotes preliminary
T1 32-34 LOCATION_OF denotes in
T2 43-47 LOCATION_OF denotes from
T3 57-61 PROCESS_OF denotes with
E1-ab-1 119-129 cui:C0079904 denotes NF-kappa B
E2-ab-1 130-133 cui:C0751998 denotes Rel
E3-ab-1 134-140 cui:C0015576 denotes family
E4-ab-1 144-165 cui:C0040648 denotes transcription factors
E5-ab-1 180-190 cui:C0185117 denotes expression
E6-ab-1 199-204 cui:C0017337 denotes genes
E7-ab-1 221-227 cui:C0439662 denotes immune
E8-ab-1 231-252 cui:C1155266 denotes inflammatory response
E9-ab-1 260-275 cui:C0040649 denotes transcriptional
T4 166-175 INTERACTS_WITH denotes regulates
E1-ab-2 299-304 cui:C0008972 denotes study
E2-ab-2 342-350 cui:C0449774 denotes patterns
E3-ab-2 354-364 cui:C0079904 denotes NF-kappa B
E4-ab-2 388-397 cui:C1547020 denotes different
E5-ab-2 398-403 cui:C0376315 denotes forms
E6-ab-2 407-420 cui:C0022408 denotes joint disease
E1-ab-3 422-429 cui:C0025663 denotes METHODS
E2-ab-3 435-446 cui:C1148673 denotes DNA binding
E3-ab-3 447-455 cui:C0439167 denotes activity
E4-ab-3 465-479 cui:C0028612 denotes nucleoproteins
E5-ab-3 505-513 cui:C1550315 denotes synovial
E6-ab-3 518-528 cui:C0205100 denotes peripheral
E7-ab-3 529-536 cui:C0039194 denotes T cells
E8-ab-3 542-550 cui:C0030705 denotes patients
E9-ab-3 564-571 cui:C0205191 denotes chronic
E10-ab-3 572-590 cui:C0035435 denotes rheumatic diseases
E11-ab-3 596-600 cui:C0205450 denotes four
E12-ab-3 606-626 cui:C0003873 denotes rheumatoid arthritis
T5 493-495 LOCATION_OF denotes in
T6 493-495 LOCATION_OF denotes in
T7 551-555 PROCESS_OF denotes with
E1-ab-4 628-632 cui:C0205451 denotes five
E2-ab-4 638-659 cui:C0949691 denotes spondyloarthropathies
E1-ab-5 665-670 cui:C0205449 denotes three
E2-ab-5 676-690 cui:C0029408 denotes osteoarthritis
E1-ab-6 693-700 cui:C1274040 denotes RESULTS
E2-ab-6 702-739 cui:C0949632 denotes Electrophoretic mobility shift assays
E3-ab-6 750-753 cui:C0205448 denotes two
E4-ab-6 763-772 cui:C0439855 denotes complexes
E5-ab-6 784-794 cui:C0079904 denotes NF-kappa B
E6-ab-6 804-807 cui:C1553631 denotes 32P
E7-ab-6 808-816 cui:C0181496 denotes labelled
E8-ab-6 817-832 cui:C0028953 denotes oligonucleotide
E9-ab-6 836-850 cui:C0028612 denotes nucleoproteins
E10-ab-6 875-882 cui:C0039194 denotes T cells
E11-ab-6 897-911 cui:C0039097 denotes synovial fluid
E12-ab-6 916-932 cui:C0229664 denotes peripheral blood
E13-ab-6 936-944 cui:C0030705 denotes patients
E14-ab-6 950-970 cui:C0003873 denotes rheumatoid arthritis
T8 861-865 LOCATION_OF denotes from
T9 945-949 PROCESS_OF denotes with
E1-ab-7 976-985 cui:C0439855 denotes complexes
E2-ab-7 999-1002 cui:C1367009 denotes p50
E3-ab-7 1003-1006 entrez:958,4790,8874 denotes p50
E4-ab-7 1022-1025 cui:C1367009 denotes p50
E5-ab-7 1026-1029 cui:C0599933 denotes p65
E1-ab-8 1044-1053 cui:C0205217 denotes Increased
E2-ab-8 1054-1064 cui:C0079904 denotes NF-kappa B
E3-ab-8 1076-1079 cui:C0012854 denotes DNA
E4-ab-8 1083-1099 cui:C0224522 denotes synovial T cells
E5-ab-8 1113-1121 cui:C0205345 denotes relative
E6-ab-8 1125-1135 cui:C0205100 denotes peripheral
E7-ab-8 1136-1143 cui:C0039194 denotes T cells
T10 1065-1072 INTERACTS_WITH denotes binding
E1-ab-9 1152-1172 cui:C0003873 denotes rheumatoid arthritis
E2-ab-9 1185-1195 cui:C0079904 denotes NF-kappa B
E3-ab-9 1199-1215 cui:C0224522 denotes synovial T cells
E4-ab-9 1244-1247 cui:C1367009 denotes p50
E5-ab-9 1248-1251 entrez:958,4790,8874 denotes p50
T11 1196-1198 LOCATION_OF denotes in
E1-ab-10 1276-1283 cui:C1561607 denotes Overall
E2-ab-10 1289-1296 cui:C1274040 denotes results
E3-ab-10 1310-1320 cui:C0079904 denotes NF-kappa B
E4-ab-10 1332-1339 cui:C0205099 denotes central
E5-ab-10 1340-1344 cui:C0449719 denotes part
E6-ab-10 1366-1378 cui:C0332448 denotes infiltrating
E7-ab-10 1379-1386 cui:C0039194 denotes T cells
E8-ab-10 1390-1418 cui:C0003873 denotes chronic rheumatoid arthritis
T12 1352-1362 AUGMENTS denotes activation
E1-ab-11 1443-1450 cui:C0521447 denotes nuclear
E2-ab-11 1451-1457 cui:C1521761 denotes factor
E3-ab-11 1475-1484 cui:C1547020 denotes different
E4-ab-11 1488-1498 cui:C0035435 denotes rheumatoid
E5-ab-11 1499-1507 cui:C1550315 denotes synovial
E6-ab-11 1508-1515 cui:C0039194 denotes T cells
E7-ab-11 1533-1538 cui:C0376315 denotes forms
E8-ab-11 1546-1566 cui:C0003873 denotes rheumatoid arthritis
E9-ab-11 1581-1595 cui:C0029408 denotes osteoarthritis
E10-ab-11 1597-1618 cui:C0949691 denotes spondyloarthropathies
T13 1499-1515 PART_OF denotes synovial T cells
R1 E3-ti-1 T1 subjectOf T cells,in
R2 E1-ti-1 T1 objectOf Nuclear factor-kappa B,in
R3 E4-ti-1 T2 subjectOf patients,from
R4 E1-ti-1 T2 objectOf Nuclear factor-kappa B,from
R5 E5-ti-1 T3 subjectOf rheumatic diseases,with
R6 E4-ti-1 T3 objectOf patients,with
R7 E4-ab-1 T4 subjectOf transcription factors,regulates
R8 E6-ab-1 T4 objectOf genes,regulates
R9 E5-ab-3 T5 subjectOf synovial,in
R10 E4-ab-3 T5 objectOf nucleoproteins,in
R11 E7-ab-3 T6 subjectOf T cells,in
R12 E4-ab-3 T6 objectOf nucleoproteins,in
R13 E10-ab-3 T7 subjectOf rheumatic diseases,with
R14 E8-ab-3 T7 objectOf patients,with
R15 E10-ab-6 T8 subjectOf T cells,from
R16 E9-ab-6 T8 objectOf nucleoproteins,from
R17 E14-ab-6 T9 subjectOf rheumatoid arthritis,with
R18 E13-ab-6 T9 objectOf patients,with
R19 E2-ab-8 T10 subjectOf NF-kappa B,binding
R20 E3-ab-8 T10 objectOf DNA,binding
R21 E3-ab-9 T11 subjectOf synovial T cells,in
R22 E2-ab-9 T11 objectOf NF-kappa B,in
R23 E3-ab-10 T12 subjectOf NF-kappa B,activation
R24 E7-ab-10 T12 objectOf T cells,activation
R25 E6-ab-11 T13 subjectOf T cells,synovial T cells
R26 E5-ab-11 T13 objectOf synovial,synovial T cells

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-103 Sentence denotes Nuclear factor-kappa B activity in T cells from patients with rheumatic diseases: a preliminary report.
S2 104-282 Sentence denotes OBJECTIVE: The NF-kappa B/Rel family of transcription factors regulates the expression of many genes involved in the immune or inflammatory response at the transcriptional level.
S3 283-421 Sentence denotes The aim of this study was to determine whether distinctive patterns of NF-kappa B activation are seen in different forms of joint disease.
S4 422-692 Sentence denotes METHODS: The DNA binding activity of these nucleoproteins was examined in purified synovial and peripheral T cells from patients with various chronic rheumatic diseases (12: four with rheumatoid arthritis; five with spondyloarthropathies; and three with osteoarthritis).
S5 693-971 Sentence denotes RESULTS: Electrophoretic mobility shift assays disclosed two specific complexes bound to a NF-kappa B specific 32P-labelled oligonucleotide in nucleoproteins extracted from purified T cells isolated from synovial fluid and peripheral blood of patients with rheumatoid arthritis.
S6 972-1043 Sentence denotes The complexes consisted of p50/p50 homodimers and p50/p65 heterodimers.
S7 1044-1144 Sentence denotes Increased NF-kappa B binding to DNA in synovial T cells was observed relative to peripheral T cells.
S8 1145-1263 Sentence denotes In non-rheumatoid arthritis, binding of NF-kappa B in synovial T cells was exclusively mediated by p50/p50 homodimers.
S9 1264-1419 Sentence denotes CONCLUSION: Overall, the results suggest that NF-kappa B may play a central part in the activation of infiltrating T cells in chronic rheumatoid arthritis.
S10 1420-1620 Sentence denotes The activation of this nuclear factor is qualitatively different in rheumatoid synovial T cells to that in other forms of non-rheumatoid arthritis (for example, osteoarthritis, spondyloarthropathies).

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-22 protein_complex denotes Nuclear factor-kappa B
T2 35-42 cell_type denotes T cells
T3 48-56 multi_cell denotes patients
T4 62-80 other_name denotes rheumatic diseases
T5 119-140 protein_molecule denotes NF-kappa B/Rel family
T6 144-165 protein_family_or_group denotes transcription factors
T7 260-281 other_name denotes transcriptional level
T8 354-364 protein_complex denotes NF-kappa B
T9 465-479 protein_family_or_group denotes nucleoproteins
T10 542-550 multi_cell denotes patients
T11 572-590 other_name denotes rheumatic diseases
T12 606-626 other_name denotes rheumatoid arthritis
T13 638-659 other_name denotes spondyloarthropathies
T14 676-690 other_name denotes osteoarthritis
T15 702-739 other_name denotes Electrophoretic mobility shift assays
T16 784-794 protein_complex denotes NF-kappa B
T17 836-850 protein_family_or_group denotes nucleoproteins
T18 866-882 cell_type denotes purified T cells
T19 897-911 tissue denotes synovial fluid
T20 916-932 tissue denotes peripheral blood
T21 936-944 multi_cell denotes patients
T22 950-970 other_name denotes rheumatoid arthritis
T23 976-985 protein_complex denotes complexes
T24 999-1017 protein_complex denotes p50/p50 homodimers
T25 1054-1064 protein_complex denotes NF-kappa B
T26 1083-1099 cell_type denotes synovial T cells
T27 1185-1195 protein_complex denotes NF-kappa B
T28 1199-1215 cell_type denotes synovial T cells
T29 1244-1262 protein_complex denotes p50/p50 homodimers
T30 1310-1320 protein_complex denotes NF-kappa B
T31 1366-1386 cell_type denotes infiltrating T cells
T32 1390-1418 other_name denotes chronic rheumatoid arthritis
T33 1488-1498 cell_type denotes rheumatoid
T34 1499-1515 cell_type denotes synovial T cells
T35 1542-1566 other_name denotes non-rheumatoid arthritis
T36 1581-1595 other_name denotes osteoarthritis
T37 1597-1618 other_name denotes spondyloarthropathies

metamap-sample

Id Subject Object Predicate Lexical cue
T4 36-43 C0039194 denotes cells
T9 1-23 C0079904 denotes uclear factor-kappa B
T11 63-81 C0035435 denotes heumatic diseases:
T14 49-57 C0030705 denotes atients
T15 97-103 C0700287 denotes eport.
T17 24-32 C0441655 denotes ctivity
T18 85-96 C0439611 denotes reliminary
T25 1620-421 C0029408 denotes
T26 1620-421 C0029408 denotes
T27 1620-421 C0028612 denotes
T28 1620-421 C0028612 denotes
T29 1620-421 C0012854 denotes
T1 1620-421 C0039194 denotes
T2 1620-421 C0039194 denotes
T3 1620-421 C0039194 denotes
T5 1620-421 C0079904 denotes
T6 1620-421 C0079904 denotes
T7 1620-421 C0079904 denotes
T8 120-130 C0079904 denotes F-kappa B/
T10 1620-421 C0035435 denotes
T12 1620-421 C0030705 denotes
T13 1620-421 C0030705 denotes
T16 1620-421 C0441655 denotes
T19 1620-421 C0003873 denotes
T20 1620-421 C0003873 denotes
T21 1620-421 C0003873 denotes
T22 1620-421 C0003873 denotes
T23 1620-421 C0949691 denotes
T24 1620-421 C0949691 denotes
T30 1620-421 C0012854 denotes
T31 1620-421 C0039097 denotes
T32 1620-421 C0028953 denotes
T33 261-276 C0040649 denotes ranscriptional
T34 1620-421 C0025664 denotes
T35 1620-421 C0282416 denotes
T36 115-116 C0018017 denotes T
T37 135-141 C0015576 denotes amily
T38 145-166 C0040648 denotes ranscription factors
T39 1620-421 C2825142 denotes
T40 1620-421 C2825142 denotes
T41 1620-421 C1704241 denotes
T42 1620-421 C1704241 denotes
T43 1620-421 C0348078 denotes
T44 399-404 C0348078 denotes orms
T45 1620-421 C1998793 denotes
T46 1620-421 C1998793 denotes
T47 1620-421 C1705242 denotes
T48 389-398 C1705242 denotes ifferent
T49 1620-421 C1550315 denotes
T50 1620-421 C1550315 denotes
T51 1620-421 C1879547 denotes
T52 1620-421 C1879547 denotes
T53 1620-421 C1518422 denotes
T54 1620-421 C1518422 denotes
T55 1620-421 C0205100 denotes
T56 1620-421 C0205100 denotes
T57 405-421 C0022408 denotes f joint disease.
T58 1620-421 C1707478 denotes
T59 1620-421 C0600138 denotes
T60 1620-421 C1707959 denotes
T61 1620-421 C1441672 denotes
T62 310-312 C1883351 denotes o
T63 1620-421 C1705535 denotes
T64 1620-421 C1523084 denotes
T65 1620-421 C0229664 denotes
T66 1620-421 C0205191 denotes
T67 1620-421 C0205451 denotes
T68 232-253 C1155266 denotes nflammatory response
T69 1620-421 C0205449 denotes
T70 1620-421 C2266866 denotes
T71 1620-421 C0332128 denotes
T72 1620-421 C0205450 denotes
T73 222-228 C0439662 denotes mmune
T74 206-214 C1314939 denotes nvolved
T75 1620-421 C0205409 denotes
T76 288-291 C1947946 denotes im
T77 1620-421 C1167622 denotes
T78 1620-421 C0185115 denotes
T79 1620-421 C0127400 denotes
T80 1620-421 C0205345 denotes
T81 343-351 C0449774 denotes atterns
T82 381-385 C0205397 denotes een
T83 1620-421 C1689898 denotes
T84 1620-421 C1879652 denotes
T85 1620-421 C1553631 denotes
T86 1620-421 C0332529 denotes
T87 352-376 C1749855 denotes f NF-kappa B activation
T88 1620-421 C0181496 denotes
T89 1620-421 C3540646 denotes
T90 1620-421 C0205448 denotes
T91 1620-421 C0440102 denotes
T92 1620-421 C1148673 denotes
T93 300-305 C2603343 denotes tudy
T94 1620-421 C1521761 denotes
T95 232-244 C0333348 denotes nflammatory
T96 277-282 C0441889 denotes evel.
T97 1620-421 C0521447 denotes
T98 1620-421 C0205217 denotes
T99 1620-421 C0007634 denotes
T100 1620-421 C0332448 denotes