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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 49-76 protein denotes tumor necrosis factor-alpha
T2 124-145 cell_line denotes OM10.1 and Ach2 cells
T3 147-156 protein denotes NF-kappaB
T4 233-242 protein denotes NF-kappaB
T5 299-322 cell_type denotes latently infected cells
T6 564-573 protein denotes NF-kappaB
T7 711-732 cell_line denotes OM10.1 and Ach2 cells
T8 734-767 protein denotes Tumor necrosis factor (TNF)-alpha
T9 797-803 cell_line denotes OM10.1
T10 807-817 cell_line denotes Ach2 cells
T11 920-930 cell_line denotes Ach2 cells
T12 956-981 protein denotes counter-anion thioglucose
T13 983-985 protein denotes TG
T14 1079-1088 protein denotes NF-kappaB
T15 1144-1147 protein denotes CAT
T16 1334-1343 protein denotes NF-kappaB

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-39 NP denotes Anti-rheumatic compound aurothioglucose
C2 106-145 NP denotes latently infected OM10.1 and Ach2 cells
C3 147-156 NP denotes NF-kappaB
C4 324-338 NP denotes Gold compounds
C5 453-467 NP denotes gold compounds
C6 480-533 NP denotes aurothioglucose (AuTG) containing monovalent gold ion
C7 564-573 NP denotes NF-kappaB
C8 632-654 NP denotes the gold compound AuTG
C9 693-732 NP denotes latently infected OM10.1 and Ach2 cells
C10 872-876 NP denotes AuTG
C11 1015-1032 NP denotes divalent gold ion
C12 1034-1040 NP denotes HAuCl3
C13 1071-1075 NP denotes AuTG
C14 1261-1270 NP denotes the cells
C15 1283-1306 NP denotes our previous hypothesis
C16 1307-1311 NP denotes that
C17 1411-1444 NP denotes the monovalent gold compound AuTG
R1 C5 C4 coref-ident gold compounds,Gold compounds
R2 C6 C1 coref-ident aurothioglucose (AuTG) containing monovalent gold ion,Anti-rheumatic compound aurothioglucose
R3 C7 C3 coref-ident NF-kappaB,NF-kappaB
R4 C8 C6 coref-ident the gold compound AuTG,aurothioglucose (AuTG) containing monovalent gold ion
R5 C9 C2 coref-ident latently infected OM10.1 and Ach2 cells,latently infected OM10.1 and Ach2 cells
R6 C10 C8 coref-ident AuTG,the gold compound AuTG
R7 C12 C11 coref-appos HAuCl3,divalent gold ion
R8 C13 C10 coref-ident AuTG,AuTG
R9 C14 C9 coref-ident the cells,latently infected OM10.1 and Ach2 cells
R10 C16 C15 coref-relat that,our previous hypothesis
R11 C17 C13 coref-ident the monovalent gold compound AuTG,AuTG

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-146 Sentence denotes Anti-rheumatic compound aurothioglucose inhibits tumor necrosis factor-alpha-induced HIV-1 replication in latently infected OM10.1 and Ach2 cells.
S2 147-213 Sentence denotes NF-kappaB is a potent cellular activator of HIV-1 gene expression.
S3 214-323 Sentence denotes Down-regulation of NF-kappaB activation is known to inhibit HIV replication from the latently infected cells.
S4 324-424 Sentence denotes Gold compounds have been effectively used for many decades in the treatment of rheumatoid arthritis.
S5 425-583 Sentence denotes We previously reported that gold compounds, especially aurothioglucose (AuTG) containing monovalent gold ion, inhibited the DNA-binding of NF-kappaB in vitro.
S6 584-733 Sentence denotes In this report we have examined the efficacy of the gold compound AuTG as an inhibitor of HIV replication in latently infected OM10.1 and Ach2 cells.
S7 734-1056 Sentence denotes Tumor necrosis factor (TNF)-alpha-induced HIV-1 replication in OM10.1 or Ach2 cells was significantly inhibited by non-cytotoxic doses of AuTG (>10 microM in OM10.1 cells and >25 F.M in Ach2 cells), while 25 microM of the counter-anion thioglucose (TG) or gold compound containing divalent gold ion, HAuCl3, had no effect.
S8 1057-1154 Sentence denotes The effect of AuTG on NF-kappaB-dependent gene expression was confirmed by a transient CAT assay.
S9 1155-1377 Sentence denotes Specific staining as well as electron microscopic examinations revealed the accumulation of metal gold in the cells, supporting our previous hypothesis that gold ions could block NF-kappaB-DNA binding by a redox mechanism.
S10 1378-1522 Sentence denotes These observations indicate that the monovalent gold compound AuTG is a potentially useful drug for the treatment of patients infected with HIV.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-23 other_organic_compound denotes Anti-rheumatic compound
T2 24-39 other_organic_compound denotes aurothioglucose
T3 49-76 protein_molecule denotes tumor necrosis factor-alpha
T4 147-156 protein_complex denotes NF-kappaB
T5 233-242 protein_complex denotes NF-kappaB
T6 274-289 other_name denotes HIV replication
T7 299-322 cell_type denotes latently infected cells
T8 324-338 atom denotes Gold compounds
T9 403-423 other_name denotes rheumatoid arthritis
T10 453-467 atom denotes gold compounds
T11 480-495 other_organic_compound denotes aurothioglucose
T12 497-501 atom denotes AuTG
T13 525-533 atom denotes gold ion
T14 564-573 protein_complex denotes NF-kappaB
T15 636-649 inorganic denotes gold compound
T16 650-654 inorganic denotes AuTG
T17 674-689 other_name denotes HIV replication
T18 734-767 protein_molecule denotes Tumor necrosis factor (TNF)-alpha
T19 797-803 cell_line denotes OM10.1
T20 807-817 cell_line denotes Ach2 cells
T21 872-876 inorganic denotes AuTG
T22 892-904 inorganic denotes OM10.1 cells
T23 920-930 cell_line denotes Ach2 cells
T24 956-981 protein_molecule denotes counter-anion thioglucose
T25 983-985 protein_molecule denotes TG
T26 990-1003 inorganic denotes gold compound
T27 1015-1023 atom denotes divalent
T28 1024-1032 atom denotes gold ion
T29 1034-1040 inorganic denotes HAuCl3
T30 1071-1075 inorganic denotes AuTG
T31 1079-1088 protein_complex denotes NF-kappaB
T32 1134-1143 other_name denotes transient
T33 1144-1147 protein_molecule denotes CAT
T34 1184-1217 other_name denotes electron microscopic examinations
T35 1247-1257 atom denotes metal gold
T36 1312-1321 atom denotes gold ions
T37 1334-1343 protein_complex denotes NF-kappaB
T38 1361-1376 other_name denotes redox mechanism
T39 1426-1439 inorganic denotes gold compound
T40 1440-1444 atom denotes AuTG
T41 1495-1503 multi_cell denotes patients
T42 1518-1521 virus denotes HIV

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 403-423 HP_0001370 denotes rheumatoid arthritis
T2 414-423 HP_0001369 denotes arthritis
T3 734-739 HP_0002664 denotes Tumor