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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 11-16 protein denotes c-Rel
T2 20-42 DNA denotes STAT5 target sequences
T3 46-72 cell_type denotes HTLV-I-transformed T cells
T4 179-186 cell_type denotes T cells
T5 309-335 cell_type denotes HTLV-I-transformed T cells
T6 378-398 protein denotes NF-kappaB/Rel family
T7 479-496 cell_type denotes transformed cells
T8 507-528 protein denotes NF-kappaB/Rel factors
T9 567-606 protein denotes T-cell growth factor interleukin (IL)-2
T10 650-654 protein denotes IL-2
T11 677-701 cell_line denotes HTLV-I-transformed cells
T12 739-760 protein denotes NF-kappaB/Rel members
T13 776-781 protein denotes c-Rel
T14 820-825 protein denotes STAT5
T15 864-868 protein denotes IL-2
T16 947-952 protein denotes c-Rel
T17 960-965 protein denotes STAT5
T18 986-1001 DNA denotes Fc gammaR1 gene
T19 1063-1068 protein denotes c-Rel
T20 1076-1096 DNA denotes Fc gammaR1 STAT site
T21 1118-1142 cell_type denotes peripheral blood T cells
T22 1290-1303 protein denotes NF-kappaB/Rel
T23 1345-1371 cell_line denotes HTLV-I-transformed T cells
T24 1407-1413 DNA denotes kappaB
T25 1426-1440 DNA denotes STAT enhancers

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 11-16 NP denotes c-Rel
C2 46-72 NP denotes HTLV-I-transformed T cells
C3 150-186 NP denotes subsequent transformation of T cells
C4 188-193 NP denotes which
C5 309-335 NP denotes HTLV-I-transformed T cells
C6 378-423 NP denotes NF-kappaB/Rel family of transcription factors
C7 425-430 NP denotes which
C8 473-496 NP denotes these transformed cells
C9 507-528 NP denotes NF-kappaB/Rel factors
C10 626-630 NP denotes they
C11 677-701 NP denotes HTLV-I-transformed cells
C12 776-781 NP denotes c-Rel
C13 820-825 NP denotes STAT5
C14 827-897 NP denotes a key transcription factor mediating IL-2-induced T-cell proliferation
C15 947-952 NP denotes c-Rel
C16 1063-1068 NP denotes c-Rel
C17 1112-1142 NP denotes human peripheral blood T cells
C18 1236-1247 NP denotes these cells
C19 1269-1284 NP denotes the possibility
C20 1285-1289 NP denotes that
C21 1290-1303 NP denotes NF-kappaB/Rel
C22 1345-1371 NP denotes HTLV-I-transformed T cells
R1 C4 C3 coref-relat which,subsequent transformation of T cells
R2 C5 C2 coref-ident HTLV-I-transformed T cells,HTLV-I-transformed T cells
R3 C7 C6 coref-relat which,NF-kappaB/Rel family of transcription factors
R4 C8 C5 coref-ident these transformed cells,HTLV-I-transformed T cells
R5 C9 C6 coref-ident NF-kappaB/Rel factors,NF-kappaB/Rel family of transcription factors
R6 C10 C9 coref-pron they,NF-kappaB/Rel factors
R7 C11 C8 coref-ident HTLV-I-transformed cells,these transformed cells
R8 C12 C1 coref-ident c-Rel,c-Rel
R9 C14 C13 coref-appos a key transcription factor mediating IL-2-induced T-cell proliferation,STAT5
R10 C15 C12 coref-ident c-Rel,c-Rel
R11 C16 C15 coref-ident c-Rel,c-Rel
R12 C18 C17 coref-ident these cells,human peripheral blood T cells
R13 C20 C19 coref-relat that,the possibility
R14 C21 C9 coref-ident NF-kappaB/Rel,NF-kappaB/Rel factors
R15 C22 C11 coref-ident HTLV-I-transformed T cells,HTLV-I-transformed cells

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-73 Sentence denotes Binding of c-Rel to STAT5 target sequences in HTLV-I-transformed T cells.
S2 74-288 Sentence denotes The type I human T-cell leukemia virus (HTLV-I) induces abnormal growth and subsequent transformation of T cells, which is associated with the development of an acute T-cell malignancy termed adult T-cell leukemia.
S3 289-497 Sentence denotes A characteristic of HTLV-I-transformed T cells is the constitutive nuclear expression of NF-kappaB/Rel family of transcription factors, which appears to be essential for the growth of these transformed cells.
S4 498-702 Sentence denotes Although NF-kappaB/Rel factors are known to induce the expression of T-cell growth factor interleukin (IL)-2, it is unclear how they participate in the IL-2-independent growth of HTLV-I-transformed cells.
S5 703-898 Sentence denotes In this study, we show that certain NF-kappaB/Rel members, predominantly c-Rel, interact with enhancer sequences for STAT5, a key transcription factor mediating IL-2-induced T-cell proliferation.
S6 899-1051 Sentence denotes Reporter gene assays reveal that the binding of c-Rel to the STAT5 site present in the Fc gammaR1 gene leads to potent transactivation of this enhancer.
S7 1052-1248 Sentence denotes Binding of c-Rel to the Fc gammaR1 STAT site also occurs in human peripheral blood T cells immortalized with HTLV-I in vitro and is correlated with enhanced levels of proliferation of these cells.
S8 1249-1441 Sentence denotes These results raise the possibility that NF-kappaB/Rel may participate in the growth control of HTLV-I-transformed T cells by regulating genes driven by both kappaB and certain STAT enhancers.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 11-16 protein_molecule denotes c-Rel
T2 20-42 DNA_domain_or_region denotes STAT5 target sequences
T3 46-72 cell_type denotes HTLV-I-transformed T cells
T4 78-112 virus denotes type I human T-cell leukemia virus
T5 114-120 virus denotes HTLV-I
T6 179-186 cell_type denotes T cells
T7 235-258 other_name denotes acute T-cell malignancy
T8 266-287 other_name denotes adult T-cell leukemia
T9 309-315 virus denotes HTLV-I
T10 378-398 protein_family_or_group denotes NF-kappaB/Rel family
T11 479-496 cell_type denotes transformed cells
T12 507-528 protein_family_or_group denotes NF-kappaB/Rel factors
T13 567-606 protein_molecule denotes T-cell growth factor interleukin (IL)-2
T14 650-654 protein_molecule denotes IL-2
T15 677-683 virus denotes HTLV-I
T16 683-701 cell_type denotes -transformed cells
T17 739-760 protein_family_or_group denotes NF-kappaB/Rel members
T18 776-781 protein_molecule denotes c-Rel
T19 820-825 protein_molecule denotes STAT5
T20 864-868 protein_molecule denotes IL-2
T21 947-952 protein_molecule denotes c-Rel
T22 960-965 protein_molecule denotes STAT5
T23 986-1001 DNA_domain_or_region denotes Fc gammaR1 gene
T24 1063-1068 protein_molecule denotes c-Rel
T25 1076-1096 DNA_domain_or_region denotes Fc gammaR1 STAT site
T26 1118-1142 cell_type denotes peripheral blood T cells
T27 1161-1167 virus denotes HTLV-I
T28 1290-1303 protein_family_or_group denotes NF-kappaB/Rel
T29 1345-1351 virus denotes HTLV-I
T30 1407-1413 DNA_domain_or_region denotes kappaB
T31 1426-1440 DNA_domain_or_region denotes STAT enhancers

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 98-106 HP_0001909 denotes leukemia
T2 130-145 HP_0001507 denotes abnormal growth
T3 279-287 HP_0001909 denotes leukemia