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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-18 protein denotes Osteoclast markers
T2 55-100 cell_type denotes human peripheral blood mononuclear precursors
T3 127-144 cell_type denotes human osteoclasts
T4 167-186 cell_type denotes hematopoietic cells
T5 331-349 protein denotes osteoclast markers
T6 391-438 cell_type denotes nonmobilized peripheral blood mononuclear cells
T7 440-444 cell_type denotes PBMC
T8 471-484 cell_type denotes stromal cells
T9 486-500 protein denotes growth factors
T10 602-606 cell_type denotes PBMC
T11 675-692 cell_line denotes adherent colonies
T12 696-754 cell_line denotes tartrate resistant acid phosphatase positive (TRAP+) cells
T13 805-819 cell_type denotes adherent cells
T14 891-895 protein denotes TRAP
T15 900-958 protein denotes sodium fluoride-resistant- alpha-naphthyl-acetate-esterase
T16 960-969 protein denotes NaF-R-NSE
T17 1047-1058 cell_type denotes osteoclasts
T18 1060-1080 protein denotes vitronectin receptor
T19 1082-1084 protein denotes VR
T20 1087-1106 protein denotes calcitonin receptor
T21 1108-1112 protein denotes TRAP
T22 1114-1133 protein denotes cathepsin K protein
T23 1139-1143 RNA denotes mRNA
T24 1235-1251 cell_line denotes VR+, TRAP+ cells
T25 1427-1450 cell_type denotes preosteoclast phenotype
T26 1498-1519 cell_type denotes osteoclast-like cells
T27 1608-1630 protein denotes osteoprotegerin ligand
T28 1632-1636 protein denotes OPGL
T29 1642-1675 protein denotes osteoclast differentiation factor
T30 1691-1696 protein denotes RANKL
T31 1701-1707 protein denotes TRANCE
T32 1734-1748 cell_type denotes adherent cells
T33 1808-1818 cell_type denotes osteoclast
T34 1905-1909 cell_type denotes PBMC
T35 2042-2053 cell_type denotes osteoclasts

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-18 NP denotes Osteoclast markers
C2 127-144 NP denotes human osteoclasts
C4 331-349 NP denotes osteoclast markers
C3 314-349 NP denotes cells expressing osteoclast markers
C5 542-547 NP denotes their
C6 669-754 NP denotes small adherent colonies of tartrate resistant acid phosphatase positive (TRAP+) cells
C7 799-819 NP denotes These adherent cells
C8 1047-1058 NP denotes osteoclasts
C9 1318-1336 NP denotes Resorption lacunae
C10 1373-1383 NP denotes these pits
C11 1452-1456 NP denotes they
C12 1470-1519 NP denotes the activity of a subset of osteoclast-like cells
C13 1520-1524 NP denotes that
C14 1608-1637 NP denotes osteoprotegerin ligand (OPGL)
C15 1639-1708 NP denotes an osteoclast differentiation factor (also known as RANKL and TRANCE)
C16 1734-1748 NP denotes adherent cells
C17 1756-1840 NP denotes an adherent population of cells, with preosteoclast/osteoclast phenotypic properties
C18 1939-1950 NP denotes these cells
C19 2042-2053 NP denotes osteoclasts
R1 C4 C1 coref-ident osteoclast markers,Osteoclast markers
R2 C5 C3 coref-pron their,cells expressing osteoclast markers
R3 C7 C6 coref-ident These adherent cells,small adherent colonies of tartrate resistant acid phosphatase positive (TRAP+) cells
R4 C8 C2 coref-ident osteoclasts,human osteoclasts
R5 C10 C9 coref-ident these pits,Resorption lacunae
R6 C11 C10 coref-pron they,these pits
R7 C13 C12 coref-relat that,the activity of a subset of osteoclast-like cells
R8 C15 C14 coref-appos an osteoclast differentiation factor (also known as RANKL and TRANCE),osteoprotegerin ligand (OPGL)
R9 C16 C7 coref-ident adherent cells,These adherent cells
R10 C18 C17 coref-ident these cells,"an adherent population of cells, with preosteoclast/osteoclast phenotypic properties"
R11 C19 C8 coref-ident osteoclasts,osteoclasts

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-101 Sentence denotes Osteoclast markers accumulate on cells developing from human peripheral blood mononuclear precursors.
S2 102-292 Sentence denotes Recent studies show that human osteoclasts develop in vitro from hematopoietic cells; however, special cultures conditions and/or cytokine mobilized peripheral blood are apparently required.
S3 293-558 Sentence denotes Here, we report that cells expressing osteoclast markers differentiate from precursors present in nonmobilized peripheral blood mononuclear cells (PBMC), without the addition of stromal cells, growth factors, cytokines or steroids; and characterize their phenotype.
S4 559-798 Sentence denotes Three days after establishing high-density PBMC cultures (1.5 x 10(6) cells/cm2), in serum-containing medium, small adherent colonies of tartrate resistant acid phosphatase positive (TRAP+) cells emerge, amidst massive monocyte cell death.
S5 799-971 Sentence denotes These adherent cells have an eccentrically placed, round nucleus, and express low levels of TRAP and sodium fluoride-resistant- alpha-naphthyl-acetate-esterase (NaF-R-NSE).
S6 972-1211 Sentence denotes Over the next week, this cell population accumulates phenotypic markers of osteoclasts (vitronectin receptor [VR], calcitonin receptor, TRAP, cathepsin K protein, and mRNA) with increased nuclearity, covering the entire surface by 15 days.
S7 1212-1317 Sentence denotes When cultured on bone, VR+, TRAP+ cells of low multinuclearity appear and cover up to 50% of the surface.
S8 1318-1363 Sentence denotes Resorption lacunae can be observed by day 22.
S9 1364-1591 Sentence denotes Although these pits are not nearly as numerous as the cells of preosteoclast phenotype, they do represent the activity of a subset of osteoclast-like cells that has achieved osteoclastic maturity under these culture conditions.
S10 1592-1749 Sentence denotes Transcripts for osteoprotegerin ligand (OPGL), an osteoclast differentiation factor (also known as RANKL and TRANCE) are expressed, likely by adherent cells.
S11 1750-1910 Sentence denotes Thus, an adherent population of cells, with preosteoclast/osteoclast phenotypic properties, arises selectively under simple culture conditions from normal PBMC.
S12 1911-2054 Sentence denotes Further characterization of these cells should identify factors involved in the growth, terminal differentiation and activation of osteoclasts.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-10 cell_type denotes Osteoclast
T2 55-100 cell_type denotes human peripheral blood mononuclear precursors
T3 127-144 cell_type denotes human osteoclasts
T4 167-186 cell_type denotes hematopoietic cells
T5 232-267 tissue denotes cytokine mobilized peripheral blood
T6 331-341 cell_type denotes osteoclast
T7 391-438 cell_type denotes nonmobilized peripheral blood mononuclear cells
T8 440-444 cell_type denotes PBMC
T9 471-484 cell_type denotes stromal cells
T10 486-500 protein_family_or_group denotes growth factors
T11 515-523 lipid denotes steroids
T12 589-601 other_name denotes high-density
T13 602-606 cell_type denotes PBMC
T14 675-692 cell_line denotes adherent colonies
T15 696-754 cell_line denotes tartrate resistant acid phosphatase positive (TRAP+) cells
T16 770-797 other_name denotes massive monocyte cell death
T17 805-819 cell_type denotes adherent cells
T18 850-863 cell_component denotes round nucleus
T19 891-895 protein_molecule denotes TRAP
T20 900-958 protein_molecule denotes sodium fluoride-resistant- alpha-naphthyl-acetate-esterase
T21 960-969 protein_molecule denotes NaF-R-NSE
T22 1047-1058 cell_type denotes osteoclasts
T23 1060-1080 protein_family_or_group denotes vitronectin receptor
T24 1082-1084 protein_family_or_group denotes VR
T25 1087-1106 protein_family_or_group denotes calcitonin receptor
T26 1108-1112 protein_molecule denotes TRAP
T27 1114-1133 protein_molecule denotes cathepsin K protein
T28 1139-1143 RNA_family_or_group denotes mRNA
T29 1229-1233 tissue denotes bone
T30 1235-1237 protein_family_or_group denotes VR
T31 1240-1244 protein_molecule denotes TRAP
T32 1318-1336 tissue denotes Resorption lacunae
T33 1427-1450 cell_type denotes preosteoclast phenotype
T34 1498-1508 cell_type denotes osteoclast
T35 1608-1630 protein_molecule denotes osteoprotegerin ligand
T36 1632-1636 protein_molecule denotes OPGL
T37 1642-1652 cell_type denotes osteoclast
T38 1691-1696 protein_molecule denotes RANKL
T39 1701-1707 protein_molecule denotes TRANCE
T40 1734-1748 cell_type denotes adherent cells
T41 1794-1808 other_name denotes preosteoclast/
T42 1808-1818 cell_type denotes osteoclast
T43 1905-1909 cell_type denotes PBMC
T44 1999-2023 other_name denotes terminal differentiation
T45 2028-2038 other_name denotes activation
T46 2042-2053 cell_type denotes osteoclasts

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 1975-1997 HP_0001507 denotes involved in the growth