PubMed:10024664 / 1174-1519 JSONTXT

{"project":"Glycan-Motif","denotations":[{"id":"T7","span":{"begin":333,"end":344},"obj":"https://glytoucan.org/Structures/Glycans/G81533KY"}],"text":"Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid."}

{"project":"GlyCosmos6-Glycan-Motif-Image","denotations":[{"id":"T7","span":{"begin":333,"end":344},"obj":"Glycan_Motif"}],"attributes":[{"id":"A7","pred":"image","subj":"T7","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY"}],"text":"Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid."}

{"project":"GlyCosmos6-Glycan-Motif-Structure","denotations":[{"id":"T7","span":{"begin":333,"end":344},"obj":"https://glytoucan.org/Structures/Glycans/G81533KY"}],"text":"Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid."}

{"project":"sentences","denotations":[{"id":"TextSentencer_T7","span":{"begin":0,"end":345},"obj":"Sentence"},{"id":"T7","span":{"begin":0,"end":345},"obj":"Sentence"},{"id":"T7","span":{"begin":0,"end":345},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid."}

{"project":"GlycoBiology-FMA","denotations":[{"id":"_T28","span":{"begin":41,"end":46},"obj":"FMAID:169002"},{"id":"_T29","span":{"begin":41,"end":46},"obj":"FMAID:68646"},{"id":"_T30","span":{"begin":65,"end":70},"obj":"FMAID:68646"},{"id":"_T31","span":{"begin":65,"end":70},"obj":"FMAID:169002"},{"id":"_T32","span":{"begin":240,"end":245},"obj":"FMAID:169002"},{"id":"_T33","span":{"begin":240,"end":245},"obj":"FMAID:68646"},{"id":"_T34","span":{"begin":278,"end":281},"obj":"FMAID:167182"}],"namespaces":[{"prefix":"FMAID","uri":"http://purl.org/sig/ont/fma/fma"}],"text":"Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid."}

{"project":"uniprot-human","denotations":[{"id":"T7","span":{"begin":287,"end":290},"obj":"http://www.uniprot.org/uniprot/P27352"}],"text":"Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid."}

{"project":"uniprot-mouse","denotations":[{"id":"T7","span":{"begin":287,"end":290},"obj":"http://www.uniprot.org/uniprot/P52787"}],"text":"Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid."}

{"project":"GlycoBiology-NCBITAXON","denotations":[{"id":"T5","span":{"begin":41,"end":46},"obj":"http://purl.bioontology.org/ontology/STY/T025"},{"id":"T6","span":{"begin":65,"end":70},"obj":"http://purl.bioontology.org/ontology/STY/T025"},{"id":"T7","span":{"begin":240,"end":245},"obj":"http://purl.bioontology.org/ontology/STY/T025"}],"text":"Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid."}

{"project":"GO-BP","denotations":[{"id":"T9","span":{"begin":31,"end":38},"obj":"http://purl.obolibrary.org/obo/GO_0043336"},{"id":"T10","span":{"begin":55,"end":62},"obj":"http://purl.obolibrary.org/obo/GO_0043336"},{"id":"T18","span":{"begin":184,"end":201},"obj":"http://purl.obolibrary.org/obo/GO_0050871"},{"id":"T19","span":{"begin":238,"end":256},"obj":"http://purl.obolibrary.org/obo/GO_0050871"},{"id":"T29","span":{"begin":79,"end":96},"obj":"http://purl.obolibrary.org/obo/GO_0032393"},{"id":"T30","span":{"begin":79,"end":96},"obj":"http://purl.obolibrary.org/obo/GO_0032394"},{"id":"T31","span":{"begin":79,"end":96},"obj":"http://purl.obolibrary.org/obo/GO_0032395"},{"id":"T32","span":{"begin":79,"end":96},"obj":"http://purl.obolibrary.org/obo/GO_0042110"},{"id":"T33","span":{"begin":79,"end":96},"obj":"http://purl.obolibrary.org/obo/GO_0045582"},{"id":"T34","span":{"begin":79,"end":96},"obj":"http://purl.obolibrary.org/obo/GO_0050798"},{"id":"T35","span":{"begin":79,"end":96},"obj":"http://purl.obolibrary.org/obo/GO_0050863"},{"id":"T36","span":{"begin":79,"end":96},"obj":"http://purl.obolibrary.org/obo/GO_0051132"},{"id":"T37","span":{"begin":79,"end":96},"obj":"http://purl.obolibrary.org/obo/GO_1903905"},{"id":"T38","span":{"begin":79,"end":96},"obj":"http://purl.obolibrary.org/obo/GO_0042102"},{"id":"T39","span":{"begin":81,"end":96},"obj":"http://purl.obolibrary.org/obo/GO_0001775"},{"id":"T40","span":{"begin":186,"end":201},"obj":"http://purl.obolibrary.org/obo/GO_0001775"},{"id":"T41","span":{"begin":240,"end":256},"obj":"http://purl.obolibrary.org/obo/GO_0001775"},{"id":"T42","span":{"begin":184,"end":201},"obj":"http://purl.obolibrary.org/obo/GO_0002904"},{"id":"T43","span":{"begin":238,"end":256},"obj":"http://purl.obolibrary.org/obo/GO_0002904"},{"id":"T44","span":{"begin":184,"end":201},"obj":"http://purl.obolibrary.org/obo/GO_0045579"},{"id":"T45","span":{"begin":238,"end":256},"obj":"http://purl.obolibrary.org/obo/GO_0045579"},{"id":"T46","span":{"begin":184,"end":201},"obj":"http://purl.obolibrary.org/obo/GO_0002672"},{"id":"T47","span":{"begin":238,"end":256},"obj":"http://purl.obolibrary.org/obo/GO_0002672"},{"id":"T48","span":{"begin":184,"end":201},"obj":"http://purl.obolibrary.org/obo/GO_0002869"},{"id":"T49","span":{"begin":238,"end":256},"obj":"http://purl.obolibrary.org/obo/GO_0002869"},{"id":"T50","span":{"begin":184,"end":201},"obj":"http://purl.obolibrary.org/obo/GO_0030890"},{"id":"T51","span":{"begin":238,"end":256},"obj":"http://purl.obolibrary.org/obo/GO_0030890"},{"id":"T52","span":{"begin":184,"end":201},"obj":"http://purl.obolibrary.org/obo/GO_0050864"},{"id":"T53","span":{"begin":238,"end":256},"obj":"http://purl.obolibrary.org/obo/GO_0050864"},{"id":"T54","span":{"begin":184,"end":201},"obj":"http://purl.obolibrary.org/obo/GO_0050869"},{"id":"T55","span":{"begin":238,"end":256},"obj":"http://purl.obolibrary.org/obo/GO_0050869"},{"id":"T56","span":{"begin":228,"end":239},"obj":"http://purl.obolibrary.org/obo/GO_0004066"}],"text":"Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid."}

{"project":"GO-MF","denotations":[{"id":"T6","span":{"begin":184,"end":201},"obj":"http://purl.obolibrary.org/obo/GO_0003823"},{"id":"T7","span":{"begin":238,"end":256},"obj":"http://purl.obolibrary.org/obo/GO_0003823"}],"text":"Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid."}

{"project":"GO-CC","denotations":[{"id":"T10","span":{"begin":81,"end":85},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T11","span":{"begin":186,"end":190},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T16","span":{"begin":41,"end":46},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T17","span":{"begin":65,"end":70},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T18","span":{"begin":240,"end":245},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T6","span":{"begin":79,"end":85},"obj":"Body_part"},{"id":"T7","span":{"begin":184,"end":190},"obj":"Body_part"}],"attributes":[{"id":"A6","pred":"uberon_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CL_0000236"}],"text":"Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid."}

{"project":"Glycosmos15-CL","denotations":[{"id":"T9","span":{"begin":39,"end":46},"obj":"Cell"},{"id":"T10","span":{"begin":63,"end":70},"obj":"Cell"},{"id":"T11","span":{"begin":79,"end":85},"obj":"Cell"},{"id":"T12","span":{"begin":184,"end":190},"obj":"Cell"},{"id":"T13","span":{"begin":238,"end":245},"obj":"Cell"}],"attributes":[{"id":"A9","pred":"cl_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CL:0000236"},{"id":"A10","pred":"cl_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CL:0000084"},{"id":"A11","pred":"cl_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CL:0000084"},{"id":"A12","pred":"cl_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CL:0000236"},{"id":"A13","pred":"cl_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CL:0000236"}],"text":"Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid."}