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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 90-109 protein denotes immunophilin FKBP51
T2 221-245 protein denotes glucocorticoid receptors
T3 247-250 protein denotes GRs
T4 319-321 protein denotes GR
T5 382-400 protein denotes squirrel monkey GR
T6 534-561 cell_type denotes squirrel monkey lymphocytes
T7 563-566 cell_type denotes SML
T8 709-725 protein denotes GR heterocomplex
T9 729-732 cell_type denotes SML
T10 737-754 cell_type denotes human lymphocytes
T11 756-758 cell_type denotes HL
T12 779-798 protein denotes immunophilin FKBP51
T13 821-824 cell_type denotes SML
T14 845-851 protein denotes FKBP52
T15 855-858 cell_type denotes SML
T16 912-925 protein denotes immunophilins
T17 1032-1038 protein denotes FKBP51
T18 1043-1049 protein denotes FKBP52
T19 1159-1165 protein denotes FKBP51
T20 1199-1205 protein denotes FKBP51
T21 1209-1240 protein denotes heat shock protein 90 complexes
T22 1244-1247 cell_type denotes SML
T23 1266-1269 cell_type denotes SML
T24 1274-1284 cell_line denotes L929 cells
T25 1361-1367 protein denotes FKBP51
T26 1373-1391 protein denotes GR heterocomplexes
T27 1407-1410 cell_type denotes SML
T28 1466-1475 cell_line denotes COS cells
T29 1503-1509 protein denotes FKBP51
T30 1534-1537 cell_type denotes SML
T31 1585-1591 protein denotes FKBP51
T32 1597-1615 protein denotes GR heterocomplexes
T33 1667-1673 protein denotes FKBP51

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 29-48 NP denotes the squirrel monkey
C2 86-109 NP denotes the immunophilin FKBP51
C3 111-127 NP denotes Squirrel monkeys
C4 132-152 NP denotes neotropical primates
C5 153-157 NP denotes that
C6 221-251 NP denotes glucocorticoid receptors (GRs)
C7 303-321 NP denotes squirrel monkey GR
C8 360-372 NP denotes the receptor
C9 382-400 NP denotes squirrel monkey GR
C10 452-468 NP denotes squirrel monkeys
C12 477-493 NP denotes a soluble factor
C13 494-498 NP denotes that
C15 534-567 NP denotes squirrel monkey lymphocytes (SML)
C14 521-588 NP denotes cytosol from squirrel monkey lymphocytes (SML) and mouse L929 cells
C11 477-628 NP denotes a soluble factor that, in mixing studies of cytosol from squirrel monkey lymphocytes (SML) and mouse L929 cells, reduced GR binding affinity by 11-fold
C16 655-666 NP denotes this factor
C17 729-732 NP denotes SML
C18 775-798 NP denotes The immunophilin FKBP51
C19 821-824 NP denotes SML
C20 833-844 NP denotes HL cytosol;
C21 845-851 NP denotes FKBP52
C22 855-858 NP denotes SML
C23 870-874 NP denotes that
C24 878-888 NP denotes HL cytosol
C25 912-925 NP denotes immunophilins
C27 1032-1038 NP denotes FKBP51
C28 1043-1049 NP denotes FKBP52
C26 1032-1049 NP denotes FKBP51 and FKBP52
C29 1159-1165 NP denotes FKBP51
C30 1199-1205 NP denotes FKBP51
C31 1244-1248 NP denotes SML;
C33 1266-1269 NP denotes SML
C32 1254-1284 NP denotes cytosols of SML and L929 cells
C34 1313-1323 NP denotes GR binding
C35 1361-1367 NP denotes FKBP51
C36 1373-1392 NP denotes GR heterocomplexes;
C38 1422-1432 NP denotes GR binding
C37 1407-1432 NP denotes SML cytosol on GR binding
C39 1487-1510 NP denotes squirrel monkey FKBP51;
C41 1549-1559 NP denotes GR binding
C40 1534-1559 NP denotes SML cytosol on GR binding
C42 1585-1591 NP denotes FKBP51
C43 1597-1615 NP denotes GR heterocomplexes
C44 1653-1663 NP denotes GR binding
C45 1667-1673 NP denotes FKBP51
R1 C3 C1 coref-ident Squirrel monkeys,the squirrel monkey
R2 C5 C4 coref-relat that,neotropical primates
R3 C8 C6 coref-ident the receptor,glucocorticoid receptors (GRs)
R4 C9 C7 coref-ident squirrel monkey GR,squirrel monkey GR
R5 C10 C3 coref-ident squirrel monkeys,Squirrel monkeys
R6 C13 C12 coref-relat that,a soluble factor
R7 C16 C11 coref-ident this factor,"a soluble factor that, in mixing studies of cytosol from squirrel monkey lymphocytes (SML) and mouse L929 cells, reduced GR binding affinity by 11-fold"
R8 C17 C15 coref-ident SML,squirrel monkey lymphocytes (SML)
R9 C18 C2 coref-ident The immunophilin FKBP51,the immunophilin FKBP51
R10 C19 C17 coref-ident SML,SML
R11 C22 C19 coref-ident SML,SML
R12 C23 C21 coref-pron that,FKBP52
R13 C24 C20 coref-ident HL cytosol,HL cytosol;
R14 C27 C18 coref-ident FKBP51,The immunophilin FKBP51
R15 C28 C21 coref-ident FKBP52,FKBP52
R16 C26 C25 coref-ident FKBP51 and FKBP52,immunophilins
R17 C29 C27 coref-ident FKBP51,FKBP51
R18 C30 C29 coref-ident FKBP51,FKBP51
R19 C31 C22 coref-ident SML;,SML
R20 C33 C31 coref-ident SML,SML;
R21 C32 C14 coref-ident cytosols of SML and L929 cells,cytosol from squirrel monkey lymphocytes (SML) and mouse L929 cells
R22 C35 C30 coref-ident FKBP51,FKBP51
R23 C38 C34 coref-ident GR binding,GR binding
R24 C39 C35 coref-ident squirrel monkey FKBP51;,FKBP51
R25 C41 C38 coref-ident GR binding,GR binding
R26 C40 C37 coref-ident SML cytosol on GR binding,SML cytosol on GR binding
R27 C42 C39 coref-ident FKBP51,squirrel monkey FKBP51;
R28 C43 C36 coref-ident GR heterocomplexes,GR heterocomplexes;
R29 C44 C41 coref-ident GR binding,GR binding
R30 C45 C42 coref-ident FKBP51,FKBP51

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-110 Sentence denotes Glucocorticoid resistance in the squirrel monkey is associated with overexpression of the immunophilin FKBP51.
S2 111-274 Sentence denotes Squirrel monkeys are neotropical primates that have high circulating cortisol to compensate for expression of glucocorticoid receptors (GRs) with reduced affinity.
S3 275-443 Sentence denotes The low binding affinity of squirrel monkey GR does not result from substitutions in the receptor, because squirrel monkey GR expressed in vitro exhibits high affinity.
S4 444-629 Sentence denotes Rather, squirrel monkeys express a soluble factor that, in mixing studies of cytosol from squirrel monkey lymphocytes (SML) and mouse L929 cells, reduced GR binding affinity by 11-fold.
S5 630-774 Sentence denotes In an effort to identify this factor, the cellular levels of components of the GR heterocomplex in SML and human lymphocytes (HL) were compared.
S6 775-889 Sentence denotes The immunophilin FKBP51 was 13-fold higher in SML than in HL cytosol; FKBP52 in SML was 42% of that in HL cytosol.
S7 890-1638 Sentence denotes A role for changes in immunophilins, causing glucocorticoid resistance in neotropical primates, is supported by the following: the changes in FKBP51 and FKBP52 were observed in cells from other neotropical primates with glucocorticoid resistance; the elevated level of FKBP51 was reflected in an abundance of FKBP51 in heat shock protein 90 complexes in SML; when cytosols of SML and L929 cells were mixed, the decrease in GR binding was associated with incorporation of FKBP51 into GR heterocomplexes; the effect of SML cytosol on GR binding was reproduced with cytosol from COS cells expressing squirrel monkey FKBP51; and both the effect of SML cytosol on GR binding and the incorporation of FKBP51 into GR heterocomplexes were blocked by FK506.
S8 1639-1763 Sentence denotes Regulation of GR binding by FKBP51 represents a previously unrecognized mechanism for regulating glucocorticoid sensitivity.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-25 other_name denotes Glucocorticoid resistance
T2 33-48 multi_cell denotes squirrel monkey
T3 90-109 protein_molecule denotes immunophilin FKBP51
T4 111-127 multi_cell denotes Squirrel monkeys
T5 132-152 multi_cell denotes neotropical primates
T6 168-188 lipid denotes circulating cortisol
T7 221-245 protein_family_or_group denotes glucocorticoid receptors
T8 247-250 protein_family_or_group denotes GRs
T9 303-318 multi_cell denotes squirrel monkey
T10 319-321 protein_family_or_group denotes GR
T11 382-397 multi_cell denotes squirrel monkey
T12 452-468 multi_cell denotes squirrel monkeys
T13 534-549 multi_cell denotes squirrel monkey
T14 563-566 cell_type denotes SML
T15 572-577 multi_cell denotes mouse
T16 598-617 other_name denotes GR binding affinity
T17 709-725 protein_complex denotes GR heterocomplex
T18 729-732 cell_type denotes SML
T19 737-754 cell_type denotes human lymphocytes
T20 756-758 cell_type denotes HL
T21 779-798 protein_molecule denotes immunophilin FKBP51
T22 821-824 cell_type denotes SML
T23 833-843 cell_component denotes HL cytosol
T24 845-851 protein_molecule denotes FKBP52
T25 855-858 cell_type denotes SML
T26 878-888 cell_component denotes HL cytosol
T27 912-925 protein_family_or_group denotes immunophilins
T28 935-960 other_name denotes glucocorticoid resistance
T29 964-984 multi_cell denotes neotropical primates
T30 1032-1038 protein_molecule denotes FKBP51
T31 1043-1049 protein_molecule denotes FKBP52
T32 1084-1104 multi_cell denotes neotropical primates
T33 1110-1135 other_name denotes glucocorticoid resistance
T34 1159-1165 protein_molecule denotes FKBP51
T35 1199-1205 protein_molecule denotes FKBP51
T36 1209-1240 protein_complex denotes heat shock protein 90 complexes
T37 1244-1247 cell_type denotes SML
T38 1266-1269 cell_type denotes SML
T39 1274-1284 cell_line denotes L929 cells
T40 1361-1367 protein_molecule denotes FKBP51
T41 1373-1391 protein_complex denotes GR heterocomplexes
T42 1407-1410 cell_type denotes SML
T43 1453-1460 cell_component denotes cytosol
T44 1466-1475 cell_line denotes COS cells
T45 1487-1502 multi_cell denotes squirrel monkey
T46 1503-1509 protein_molecule denotes FKBP51
T47 1534-1537 cell_type denotes SML
T48 1538-1545 cell_component denotes cytosol
T49 1585-1591 protein_molecule denotes FKBP51
T50 1597-1615 protein_complex denotes GR heterocomplexes
T51 1667-1673 protein_molecule denotes FKBP51
T52 1736-1762 other_name denotes glucocorticoid sensitivity