PMC:8950415 / 1804-3205 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/8950415","sourcedb":"PMC","sourceid":"8950415","source_url":"https://www.ncbi.nlm.nih.gov/pmc/8950415","text":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease of 2019 (COVID-19) has been a causative factor in the deaths of more than of 5.6 million people worldwide [1]. There is currently no firm consensus on its routes of transmission, as evidence exists that pathogenic SARS-CoV-2 aerosol particles across a distribution of sizes, play a major role, and that both droplets and aerosols are implicated [2,3,4,5,6,7,8]. “True” aerosol transmission is considered to occur from droplet nuclei, particles \u003c 5 µm, which can remain suspended in the air indefinitely and can penetrate the lower lung [9]. Particles between 5 and 10 µm can travel over shorter distances (metres, depending on surrounding air currents), and be inhaled into the upper respiratory tract; whilst even larger particles from 10 to 100 µm, most likely play a role in either direct transmission [10], where droplets land directly onto mucosal membranes from the respiratory secretions of another person; or in indirect (fomite) transmission, where they settle onto surfaces subsequently touched, and contamination is transmitted to the mucosal membranes of the face, causing infection [11]. Previous work investigated the survival of SARS-CoV-2 on different surfaces [12,13]. The work reported here focuses on the generation and size characterisation of SARS-CoV-2 in aerosol particles.","tracks":[]}