PMC:8950415 / 16836-18272 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/8950415","sourcedb":"PMC","sourceid":"8950415","source_url":"https://www.ncbi.nlm.nih.gov/pmc/8950415","text":"3.2. Nebuliser PFU Counts\nViable virus was consistently recoverable from the AGI and from all six nebuliser reservoirs following aerosolization for 5 min, across three different relative humidity ranges. The total PFU collected as an average (with standard deviation) across all RH values, were, in descending order: PARI SprintStar 2.76 × 105 (s.d. 5.06 × 104), SLAG 90 mm 2.26 × 105 (s.d. 3.92 × 105), Collison 6-jet 1.49 × 105 (s.d. 1.41 × 105), Collison 3-jet 1.21 × 105 (s.d. 3.47 × 104), Omron MicroAIR U22 1.00 × 105 (s.d. 8.99 × 104) and SLAG 1 inch 1.39 × 104 (s.d. 2.16 × 104). From these data, VF values of SARS-CoV-2 aerosols have been calculated, to estimate the impact on viability of physical forces experienced during nebulisation, with lower values indicating a larger impact on viability. Figure 2 shows that median VF values across all RH values were between 6.7 × 10−6 (Collison 6 jet) to 2.6 × 10−2 (90 mm SLAG). Overall, the SLAG nebulisers resulted in higher VF values (suggestive of their gentler mode of action on aerosol generation), compared to the four other nebuliser types, though only the 90 mm SLAG results were significantly higher than the 3-jet and 6-jet Collisons (p = 0.010). Humidity did not significantly impact VF values (p = 0.177), but values were slightly less variable at lower RH, with coefficients of variation for high, intermediate, and low RH of 206.3%, 235.2%, and 125.5%, respectively.","divisions":[{"label":"title","span":{"begin":0,"end":25}}],"tracks":[]}