PMC:8950415 / 10068-11209 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/8950415","sourcedb":"PMC","sourceid":"8950415","source_url":"https://www.ncbi.nlm.nih.gov/pmc/8950415","text":"A Henderson apparatus allows closed-circuit containment and direction of microbial aerosols generated from a nebuliser at a controlled relative humidity (Figure 1). The Henderson apparatus was used to deliver aerosols of SARS-CoV-2 at 40 L/min (balancing the total flow between the nebuliser and the Biaera unit) and the aerosols were collected at the end of the apparatus spray tube using biological samplers. The apparatus was contained within a flexible film isolator (FFI) within Containment Level 3 facilities. The challenge system is controlled by an AeroMP control unit (Biaera, Hagerstown, MD, USA). The AeroMP is a platform system designed to manage the aerosol generation, characterisation and sampling processes via a dashboard software laptop system. The aerosol management platform controls, monitors, and records all relevant parameters during an aerosol procedure including air flow rates, generated pressures, temperature and relative humidity. The software automatically monitors the conditions in the apparatus and balances the system airflows. The mean temperature during all experiments was 23.4 °C, range 21 °C to 25 °C.","tracks":[]}