PMC:88885 / 3475-4113 JSONTXT

{"project":"craft-sa-dev","denotations":[{"id":"T1044","span":{"begin":0,"end":2},"obj":"IN"},{"id":"T1045","span":{"begin":83,"end":91},"obj":"VBN"},{"id":"T1046","span":{"begin":3,"end":8},"obj":"NN"},{"id":"T1047","span":{"begin":9,"end":11},"obj":"TO"},{"id":"T1048","span":{"begin":12,"end":17},"obj":"VB"},{"id":"T1049","span":{"begin":18,"end":21},"obj":"DT"},{"id":"T1050","span":{"begin":28,"end":37},"obj":"NN"},{"id":"T1051","span":{"begin":22,"end":27},"obj":"NN"},{"id":"T1052","span":{"begin":38,"end":40},"obj":"IN"},{"id":"T1053","span":{"begin":41,"end":47},"obj":"NN"},{"id":"T1054","span":{"begin":47,"end":49},"obj":","},{"id":"T1055","span":{"begin":49,"end":52},"obj":"DT"},{"id":"T1056","span":{"begin":70,"end":78},"obj":"NN"},{"id":"T1057","span":{"begin":53,"end":58},"obj":"JJ"},{"id":"T1058","span":{"begin":59,"end":64},"obj":"NN"},{"id":"T1059","span":{"begin":65,"end":69},"obj":"NN"},{"id":"T1060","span":{"begin":79,"end":82},"obj":"VBD"},{"id":"T1061","span":{"begin":92,"end":94},"obj":"IN"},{"id":"T1062","span":{"begin":95,"end":98},"obj":"DT"},{"id":"T1063","span":{"begin":139,"end":147},"obj":"NN"},{"id":"T1064","span":{"begin":99,"end":103},"obj":"JJ"},{"id":"T1065","span":{"begin":104,"end":114},"obj":"NN"},{"id":"T1066","span":{"begin":123,"end":131},"obj":"NN"},{"id":"T1067","span":{"begin":115,"end":122},"obj":"JJ"},{"id":"T1068","span":{"begin":132,"end":133},"obj":"-LRB-"},{"id":"T1069","span":{"begin":133,"end":137},"obj":"NN"},{"id":"T1070","span":{"begin":137,"end":138},"obj":"-RRB-"},{"id":"T1071","span":{"begin":148,"end":153},"obj":"VBG"},{"id":"T1072","span":{"begin":154,"end":161},"obj":"NN"},{"id":"T1073","span":{"begin":161,"end":163},"obj":","},{"id":"T1074","span":{"begin":163,"end":168},"obj":"WDT"},{"id":"T1075","span":{"begin":169,"end":179},"obj":"VBD"},{"id":"T1076","span":{"begin":180,"end":183},"obj":"DT"},{"id":"T1077","span":{"begin":194,"end":199},"obj":"NN"},{"id":"T1078","span":{"begin":184,"end":189},"obj":"NN"},{"id":"T1079","span":{"begin":190,"end":193},"obj":"NN"},{"id":"T1080","span":{"begin":200,"end":204},"obj":"NN"},{"id":"T1081","span":{"begin":205,"end":213},"obj":"NN"},{"id":"T1082","span":{"begin":204,"end":205},"obj":"HYPH"},{"id":"T1083","span":{"begin":214,"end":215},"obj":"-LRB-"},{"id":"T1084","span":{"begin":222,"end":232},"obj":"NN"},{"id":"T1085","span":{"begin":215,"end":217},"obj":"NN"},{"id":"T1086","span":{"begin":218,"end":221},"obj":"NN"},{"id":"T1087","span":{"begin":232,"end":233},"obj":"-RRB-"},{"id":"T1088","span":{"begin":233,"end":234},"obj":"."},{"id":"T1089","span":{"begin":234,"end":486},"obj":"sentence"},{"id":"T1090","span":{"begin":235,"end":249},"obj":"NN"},{"id":"T1091","span":{"begin":356,"end":365},"obj":"VBD"},{"id":"T1092","span":{"begin":250,"end":254},"obj":"IN"},{"id":"T1093","span":{"begin":255,"end":258},"obj":"DT"},{"id":"T1094","span":{"begin":272,"end":281},"obj":"NNP"},{"id":"T1095","span":{"begin":259,"end":264},"obj":"NNP"},{"id":"T1096","span":{"begin":265,"end":271},"obj":"NNP"},{"id":"T1097","span":{"begin":282,"end":285},"obj":"CC"},{"id":"T1098","span":{"begin":286,"end":289},"obj":"DT"},{"id":"T1099","span":{"begin":318,"end":328},"obj":"NNP"},{"id":"T1100","span":{"begin":290,"end":298},"obj":"NNP"},{"id":"T1101","span":{"begin":299,"end":308},"obj":"NNP"},{"id":"T1102","span":{"begin":309,"end":317},"obj":"NNP"},{"id":"T1103","span":{"begin":349,"end":355},"obj":"NNP"},{"id":"T1104","span":{"begin":329,"end":330},"obj":"-LRB-"},{"id":"T1105","span":{"begin":330,"end":334},"obj":"NNP"},{"id":"T1106","span":{"begin":334,"end":335},"obj":"-RRB-"},{"id":"T1107","span":{"begin":336,"end":341},"obj":"NNP"},{"id":"T1108","span":{"begin":342,"end":348},"obj":"NNP"},{"id":"T1109","span":{"begin":366,"end":369},"obj":"DT"},{"id":"T1110","span":{"begin":370,"end":378},"obj":"NN"},{"id":"T1111","span":{"begin":379,"end":381},"obj":"IN"},{"id":"T1112","span":{"begin":382,"end":386},"obj":"DT"},{"id":"T1113","span":{"begin":387,"end":390},"obj":"NN"},{"id":"T1114","span":{"begin":391,"end":393},"obj":"IN"},{"id":"T1115","span":{"begin":394,"end":399},"obj":"NN"},{"id":"T1116","span":{"begin":400,"end":410},"obj":"NN"},{"id":"T1117","span":{"begin":411,"end":412},"obj":"CD"},{"id":"T1118","span":{"begin":413,"end":416},"obj":"CC"},{"id":"T1119","span":{"begin":417,"end":424},"obj":"VBD"},{"id":"T1120","span":{"begin":425,"end":427},"obj":"PRP"},{"id":"T1121","span":{"begin":431,"end":440},"obj":"VB"},{"id":"T1122","span":{"begin":428,"end":430},"obj":"TO"},{"id":"T1123","span":{"begin":441,"end":442},"obj":"DT"},{"id":"T1124","span":{"begin":452,"end":455},"obj":"NN"},{"id":"T1125","span":{"begin":443,"end":451},"obj":"JJ"},{"id":"T1126","span":{"begin":456,"end":458},"obj":"IN"},{"id":"T1127","span":{"begin":459,"end":463},"obj":"DT"},{"id":"T1128","span":{"begin":464,"end":470},"obj":"NN"},{"id":"T1129","span":{"begin":471,"end":472},"obj":"-LRB-"},{"id":"T1130","span":{"begin":472,"end":474},"obj":"CD"},{"id":"T1131","span":{"begin":474,"end":475},"obj":"-RRB-"},{"id":"T1132","span":{"begin":476,"end":477},"obj":"-LRB-"},{"id":"T1133","span":{"begin":482,"end":484},"obj":"NN"},{"id":"T1134","span":{"begin":477,"end":481},"obj":"NN"},{"id":"T1135","span":{"begin":484,"end":485},"obj":"-RRB-"},{"id":"T1136","span":{"begin":485,"end":486},"obj":"."},{"id":"T1137","span":{"begin":486,"end":638},"obj":"sentence"},{"id":"T1138","span":{"begin":487,"end":490},"obj":"DT"},{"id":"T1139","span":{"begin":495,"end":503},"obj":"NN"},{"id":"T1140","span":{"begin":491,"end":494},"obj":"NN"},{"id":"T1141","span":{"begin":513,"end":521},"obj":"VBN"},{"id":"T1142","span":{"begin":504,"end":507},"obj":"VBD"},{"id":"T1143","span":{"begin":508,"end":512},"obj":"RB"},{"id":"T1144","span":{"begin":522,"end":524},"obj":"IN"},{"id":"T1145","span":{"begin":525,"end":528},"obj":"DT"},{"id":"T1146","span":{"begin":539,"end":547},"obj":"NN"},{"id":"T1147","span":{"begin":529,"end":534},"obj":"NN"},{"id":"T1148","span":{"begin":535,"end":538},"obj":"NN"},{"id":"T1149","span":{"begin":548,"end":553},"obj":"VBG"},{"id":"T1150","span":{"begin":554,"end":560},"obj":"NN"},{"id":"T1151","span":{"begin":560,"end":562},"obj":","},{"id":"T1152","span":{"begin":562,"end":565},"obj":"CC"},{"id":"T1153","span":{"begin":566,"end":574},"obj":"JJ"},{"id":"T1154","span":{"begin":575,"end":579},"obj":"NNS"},{"id":"T1155","span":{"begin":627,"end":637},"obj":"VBN"},{"id":"T1156","span":{"begin":580,"end":583},"obj":"CC"},{"id":"T1157","span":{"begin":584,"end":589},"obj":"PRP$"},{"id":"T1158","span":{"begin":615,"end":621},"obj":"NNS"},{"id":"T1159","span":{"begin":590,"end":603},"obj":"VBG"},{"id":"T1160","span":{"begin":604,"end":614},"obj":"NNP"},{"id":"T1161","span":{"begin":622,"end":626},"obj":"VBD"},{"id":"T1162","span":{"begin":637,"end":638},"obj":"."}],"relations":[{"id":"R586","pred":"prep","subj":"T1044","obj":"T1045"},{"id":"R587","pred":"pobj","subj":"T1046","obj":"T1044"},{"id":"R588","pred":"aux","subj":"T1047","obj":"T1048"},{"id":"R589","pred":"acl","subj":"T1048","obj":"T1046"},{"id":"R590","pred":"det","subj":"T1049","obj":"T1050"},{"id":"R591","pred":"dobj","subj":"T1050","obj":"T1048"},{"id":"R592","pred":"compound","subj":"T1051","obj":"T1050"},{"id":"R593","pred":"prep","subj":"T1052","obj":"T1050"},{"id":"R594","pred":"pobj","subj":"T1053","obj":"T1052"},{"id":"R595","pred":"punct","subj":"T1054","obj":"T1045"},{"id":"R596","pred":"det","subj":"T1055","obj":"T1056"},{"id":"R597","pred":"nsubjpass","subj":"T1056","obj":"T1045"},{"id":"R598","pred":"amod","subj":"T1057","obj":"T1056"},{"id":"R599","pred":"compound","subj":"T1058","obj":"T1059"},{"id":"R600","pred":"compound","subj":"T1059","obj":"T1056"},{"id":"R601","pred":"auxpass","subj":"T1060","obj":"T1045"},{"id":"R602","pred":"prep","subj":"T1061","obj":"T1045"},{"id":"R603","pred":"det","subj":"T1062","obj":"T1063"},{"id":"R604","pred":"pobj","subj":"T1063","obj":"T1061"},{"id":"R605","pred":"amod","subj":"T1064","obj":"T1065"},{"id":"R606","pred":"nmod","subj":"T1065","obj":"T1066"},{"id":"R607","pred":"nmod","subj":"T1066","obj":"T1063"},{"id":"R608","pred":"amod","subj":"T1067","obj":"T1066"},{"id":"R609","pred":"punct","subj":"T1068","obj":"T1066"},{"id":"R610","pred":"appos","subj":"T1069","obj":"T1066"},{"id":"R611","pred":"punct","subj":"T1070","obj":"T1063"},{"id":"R612","pred":"advcl","subj":"T1071","obj":"T1045"},{"id":"R613","pred":"dobj","subj":"T1072","obj":"T1071"},{"id":"R614","pred":"punct","subj":"T1073","obj":"T1045"},{"id":"R615","pred":"dep","subj":"T1074","obj":"T1075"},{"id":"R616","pred":"advcl","subj":"T1075","obj":"T1045"},{"id":"R617","pred":"det","subj":"T1076","obj":"T1077"},{"id":"R618","pred":"dobj","subj":"T1077","obj":"T1075"},{"id":"R619","pred":"compound","subj":"T1078","obj":"T1079"},{"id":"R620","pred":"compound","subj":"T1079","obj":"T1077"},{"id":"R621","pred":"compound","subj":"T1080","obj":"T1081"},{"id":"R622","pred":"appos","subj":"T1081","obj":"T1077"},{"id":"R623","pred":"punct","subj":"T1082","obj":"T1081"},{"id":"R624","pred":"punct","subj":"T1083","obj":"T1084"},{"id":"R625","pred":"parataxis","subj":"T1084","obj":"T1077"},{"id":"R626","pred":"compound","subj":"T1085","obj":"T1084"},{"id":"R627","pred":"compound","subj":"T1086","obj":"T1084"},{"id":"R628","pred":"punct","subj":"T1087","obj":"T1084"},{"id":"R629","pred":"punct","subj":"T1088","obj":"T1045"},{"id":"R630","pred":"nsubj","subj":"T1090","obj":"T1091"},{"id":"R631","pred":"prep","subj":"T1092","obj":"T1090"},{"id":"R632","pred":"det","subj":"T1093","obj":"T1094"},{"id":"R633","pred":"pobj","subj":"T1094","obj":"T1092"},{"id":"R634","pred":"compound","subj":"T1095","obj":"T1094"},{"id":"R635","pred":"compound","subj":"T1096","obj":"T1094"},{"id":"R636","pred":"cc","subj":"T1097","obj":"T1094"},{"id":"R637","pred":"det","subj":"T1098","obj":"T1099"},{"id":"R638","pred":"nmod","subj":"T1099","obj":"T1103"},{"id":"R639","pred":"nmod","subj":"T1100","obj":"T1101"},{"id":"R640","pred":"nmod","subj":"T1101","obj":"T1099"},{"id":"R641","pred":"nmod","subj":"T1102","obj":"T1099"},{"id":"R643","pred":"punct","subj":"T1104","obj":"T1099"},{"id":"R644","pred":"appos","subj":"T1105","obj":"T1099"},{"id":"R645","pred":"punct","subj":"T1106","obj":"T1103"},{"id":"R646","pred":"compound","subj":"T1107","obj":"T1108"},{"id":"R673","pred":"compound","subj":"T1134","obj":"T1133"},{"id":"R674","pred":"punct","subj":"T1135","obj":"T1133"},{"id":"R675","pred":"punct","subj":"T1136","obj":"T1091"},{"id":"R676","pred":"det","subj":"T1138","obj":"T1139"},{"id":"R677","pred":"nsubjpass","subj":"T1139","obj":"T1141"},{"id":"R678","pred":"compound","subj":"T1140","obj":"T1139"},{"id":"R679","pred":"auxpass","subj":"T1142","obj":"T1141"},{"id":"R680","pred":"advmod","subj":"T1143","obj":"T1141"},{"id":"R681","pred":"prep","subj":"T1144","obj":"T1141"},{"id":"R682","pred":"det","subj":"T1145","obj":"T1146"},{"id":"R683","pred":"pobj","subj":"T1146","obj":"T1144"},{"id":"R684","pred":"compound","subj":"T1147","obj":"T1148"},{"id":"R685","pred":"compound","subj":"T1148","obj":"T1146"},{"id":"R686","pred":"advcl","subj":"T1149","obj":"T1141"},{"id":"R687","pred":"dobj","subj":"T1150","obj":"T1149"},{"id":"R688","pred":"punct","subj":"T1151","obj":"T1141"},{"id":"R689","pred":"cc","subj":"T1152","obj":"T1141"},{"id":"R690","pred":"amod","subj":"T1153","obj":"T1154"},{"id":"R691","pred":"nsubjpass","subj":"T1154","obj":"T1155"},{"id":"R692","pred":"conj","subj":"T1155","obj":"T1141"},{"id":"R693","pred":"cc","subj":"T1156","obj":"T1154"},{"id":"R694","pred":"poss","subj":"T1157","obj":"T1158"},{"id":"R695","pred":"conj","subj":"T1158","obj":"T1154"},{"id":"R696","pred":"amod","subj":"T1159","obj":"T1158"},{"id":"R697","pred":"compound","subj":"T1160","obj":"T1158"},{"id":"R698","pred":"auxpass","subj":"T1161","obj":"T1155"},{"id":"R699","pred":"punct","subj":"T1162","obj":"T1155"},{"id":"R649","pred":"dobj","subj":"T1110","obj":"T1091"},{"id":"R650","pred":"prep","subj":"T1111","obj":"T1110"},{"id":"R651","pred":"det","subj":"T1112","obj":"T1113"},{"id":"R652","pred":"pobj","subj":"T1113","obj":"T1111"},{"id":"R653","pred":"prep","subj":"T1114","obj":"T1110"},{"id":"R654","pred":"compound","subj":"T1115","obj":"T1116"},{"id":"R655","pred":"pobj","subj":"T1116","obj":"T1114"},{"id":"R656","pred":"nummod","subj":"T1117","obj":"T1116"},{"id":"R657","pred":"cc","subj":"T1118","obj":"T1091"},{"id":"R658","pred":"conj","subj":"T1119","obj":"T1091"},{"id":"R659","pred":"nsubj","subj":"T1120","obj":"T1121"},{"id":"R660","pred":"ccomp","subj":"T1121","obj":"T1119"},{"id":"R661","pred":"aux","subj":"T1122","obj":"T1121"},{"id":"R662","pred":"det","subj":"T1123","obj":"T1124"},{"id":"R663","pred":"dobj","subj":"T1124","obj":"T1121"},{"id":"R664","pred":"amod","subj":"T1125","obj":"T1124"},{"id":"R665","pred":"prep","subj":"T1126","obj":"T1124"},{"id":"R666","pred":"det","subj":"T1127","obj":"T1128"},{"id":"R667","pred":"pobj","subj":"T1128","obj":"T1126"},{"id":"R668","pred":"punct","subj":"T1129","obj":"T1130"},{"id":"R642","pred":"conj","subj":"T1103","obj":"T1094"},{"id":"R647","pred":"compound","subj":"T1108","obj":"T1103"},{"id":"R648","pred":"det","subj":"T1109","obj":"T1110"},{"id":"R669","pred":"parataxis","subj":"T1130","obj":"T1119"},{"id":"R670","pred":"punct","subj":"T1131","obj":"T1130"},{"id":"R671","pred":"punct","subj":"T1132","obj":"T1133"},{"id":"R672","pred":"parataxis","subj":"T1133","obj":"T1119"}],"text":"In order to clone the mouse homologue of MCOLN1, the human amino acid sequence was compared to the high throughput genomic sequence (HTGS) database using TBLASTN, which identified the mouse BAC clone RPCI-23_387H4 (GB No. AC079544.1). Correspondence with the Joint Genome Institute and the Lawrence Livermore National Laboratory (LLNL) Human Genome Center confirmed the location of this BAC to mouse chromosome 8 and allowed us to construct a physical map of this region [14] (Fig. 1A). The BAC sequence was then compared to the mouse EST database using BLASTN, and multiple ESTs and their corresponding I.M.A.G.E. clones were identified."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T983","span":{"begin":22,"end":27},"obj":"NCBITaxon:10088"},{"id":"T984","span":{"begin":28,"end":37},"obj":"SO:0000853"},{"id":"T985","span":{"begin":41,"end":47},"obj":"PR:000010252"},{"id":"T986","span":{"begin":53,"end":58},"obj":"NCBITaxon:9606"},{"id":"T987","span":{"begin":115,"end":122},"obj":"SO:0001026"},{"id":"T988","span":{"begin":184,"end":189},"obj":"NCBITaxon:10088"},{"id":"T989","span":{"begin":190,"end":193},"obj":"SO:0000153"},{"id":"T990","span":{"begin":265,"end":271},"obj":"SO:0001026"},{"id":"T991","span":{"begin":336,"end":341},"obj":"NCBITaxon:9606"},{"id":"T992","span":{"begin":342,"end":348},"obj":"SO:0001026"},{"id":"T993","span":{"begin":387,"end":390},"obj":"SO:0000153"},{"id":"T994","span":{"begin":394,"end":399},"obj":"NCBITaxon:10088"},{"id":"T995","span":{"begin":443,"end":455},"obj":"SO:0001249"},{"id":"T996","span":{"begin":491,"end":494},"obj":"SO:0000153"},{"id":"T997","span":{"begin":529,"end":534},"obj":"NCBITaxon:10088"},{"id":"T998","span":{"begin":535,"end":538},"obj":"SO:0000345"},{"id":"T999","span":{"begin":575,"end":579},"obj":"SO:0000345"}],"text":"In order to clone the mouse homologue of MCOLN1, the human amino acid sequence was compared to the high throughput genomic sequence (HTGS) database using TBLASTN, which identified the mouse BAC clone RPCI-23_387H4 (GB No. AC079544.1). Correspondence with the Joint Genome Institute and the Lawrence Livermore National Laboratory (LLNL) Human Genome Center confirmed the location of this BAC to mouse chromosome 8 and allowed us to construct a physical map of this region [14] (Fig. 1A). The BAC sequence was then compared to the mouse EST database using BLASTN, and multiple ESTs and their corresponding I.M.A.G.E. clones were identified."}

{"project":"2_test","denotations":[{"id":"11897010-11386749-10449847","span":{"begin":472,"end":474},"obj":"11386749"}],"text":"In order to clone the mouse homologue of MCOLN1, the human amino acid sequence was compared to the high throughput genomic sequence (HTGS) database using TBLASTN, which identified the mouse BAC clone RPCI-23_387H4 (GB No. AC079544.1). Correspondence with the Joint Genome Institute and the Lawrence Livermore National Laboratory (LLNL) Human Genome Center confirmed the location of this BAC to mouse chromosome 8 and allowed us to construct a physical map of this region [14] (Fig. 1A). The BAC sequence was then compared to the mouse EST database using BLASTN, and multiple ESTs and their corresponding I.M.A.G.E. clones were identified."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T1365","span":{"begin":12,"end":17},"obj":"SO_EXT:sequence_cloning_process"},{"id":"T1366","span":{"begin":22,"end":27},"obj":"NCBITaxon:10088"},{"id":"T1367","span":{"begin":28,"end":37},"obj":"SO_EXT:0000853"},{"id":"T1368","span":{"begin":41,"end":47},"obj":"PR_EXT:000010252"},{"id":"T1369","span":{"begin":53,"end":58},"obj":"NCBITaxon:9606"},{"id":"T1370","span":{"begin":59,"end":69},"obj":"CHEBI_SO_EXT:amino_acid"},{"id":"T1371","span":{"begin":70,"end":78},"obj":"SO_EXT:biological_sequence"},{"id":"T1372","span":{"begin":115,"end":122},"obj":"SO_EXT:0001026"},{"id":"T1373","span":{"begin":123,"end":131},"obj":"SO_EXT:biological_sequence"},{"id":"T1374","span":{"begin":184,"end":189},"obj":"NCBITaxon:10088"},{"id":"T1375","span":{"begin":190,"end":193},"obj":"SO_EXT:0000153"},{"id":"T1376","span":{"begin":194,"end":199},"obj":"SO_EXT:sequence_cloned_entity"},{"id":"T1377","span":{"begin":265,"end":271},"obj":"SO_EXT:0001026"},{"id":"T1378","span":{"begin":336,"end":341},"obj":"NCBITaxon:9606"},{"id":"T1379","span":{"begin":342,"end":348},"obj":"SO_EXT:0001026"},{"id":"T1380","span":{"begin":387,"end":390},"obj":"SO_EXT:0000153"},{"id":"T1381","span":{"begin":394,"end":399},"obj":"NCBITaxon:10088"},{"id":"T1382","span":{"begin":400,"end":410},"obj":"GO_SO_EXT:chromosome"},{"id":"T1383","span":{"begin":443,"end":455},"obj":"SO_EXT:0001249"},{"id":"T1384","span":{"begin":491,"end":494},"obj":"SO_EXT:0000153"},{"id":"T1385","span":{"begin":495,"end":503},"obj":"SO_EXT:biological_sequence"},{"id":"T1386","span":{"begin":529,"end":534},"obj":"NCBITaxon:10088"},{"id":"T1387","span":{"begin":535,"end":538},"obj":"SO_EXT:0000345"},{"id":"T1388","span":{"begin":575,"end":579},"obj":"SO_EXT:0000345"},{"id":"T1389","span":{"begin":615,"end":621},"obj":"SO_EXT:sequence_cloned_entity"}],"text":"In order to clone the mouse homologue of MCOLN1, the human amino acid sequence was compared to the high throughput genomic sequence (HTGS) database using TBLASTN, which identified the mouse BAC clone RPCI-23_387H4 (GB No. AC079544.1). Correspondence with the Joint Genome Institute and the Lawrence Livermore National Laboratory (LLNL) Human Genome Center confirmed the location of this BAC to mouse chromosome 8 and allowed us to construct a physical map of this region [14] (Fig. 1A). The BAC sequence was then compared to the mouse EST database using BLASTN, and multiple ESTs and their corresponding I.M.A.G.E. clones were identified."}