PMC:88885 / 1044-1606
Annnotations
craft-sa-dev
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T308 | 0-6 | NN | denotes | Mcoln1 |
T309 | 7-9 | VBZ | denotes | is |
T310 | 10-16 | RB | denotes | highly |
T311 | 17-24 | JJ | denotes | similar |
T312 | 25-27 | IN | denotes | to |
T313 | 28-34 | NN | denotes | MCOLN1 |
T314 | 34-36 | , | denotes | , |
T315 | 36-46 | RB | denotes | especially |
T316 | 47-49 | IN | denotes | in |
T317 | 50-53 | DT | denotes | the |
T318 | 68-75 | NNS | denotes | domains |
T319 | 54-67 | NN | denotes | transmembrane |
T320 | 76-79 | CC | denotes | and |
T321 | 80-83 | NN | denotes | ion |
T322 | 84-88 | NN | denotes | pore |
T323 | 89-95 | NN | denotes | region |
T324 | 95-96 | . | denotes | . |
T325 | 96-246 | sentence | denotes | Also, the late endosomal/lysosomal targeting signal is conserved, supporting the hypothesis that the protein is localized to these vesicle membranes. |
T326 | 97-101 | RB | denotes | Also |
T327 | 152-161 | VBN | denotes | conserved |
T328 | 101-103 | , | denotes | , |
T329 | 103-106 | DT | denotes | the |
T330 | 142-148 | NN | denotes | signal |
T331 | 107-111 | JJ | denotes | late |
T332 | 112-121 | JJ | denotes | endosomal |
T333 | 122-131 | JJ | denotes | lysosomal |
T334 | 121-122 | HYPH | denotes | / |
T335 | 132-141 | NN | denotes | targeting |
T336 | 149-151 | VBZ | denotes | is |
T337 | 161-163 | , | denotes | , |
T338 | 163-173 | VBG | denotes | supporting |
T339 | 174-177 | DT | denotes | the |
T340 | 178-188 | NN | denotes | hypothesis |
T341 | 189-193 | IN | denotes | that |
T342 | 209-218 | VBN | denotes | localized |
T343 | 194-197 | DT | denotes | the |
T344 | 198-205 | NN | denotes | protein |
T345 | 206-208 | VBZ | denotes | is |
T346 | 219-221 | IN | denotes | to |
T347 | 222-227 | DT | denotes | these |
T348 | 236-245 | NNS | denotes | membranes |
T349 | 228-235 | NN | denotes | vesicle |
T350 | 245-246 | . | denotes | . |
T351 | 246-327 | sentence | denotes | To date, there are very few reports describing species-specific splice variants. |
T352 | 247-249 | IN | denotes | To |
T353 | 262-265 | VBP | denotes | are |
T354 | 250-254 | NN | denotes | date |
T355 | 254-256 | , | denotes | , |
T356 | 256-261 | EX | denotes | there |
T357 | 266-270 | RB | denotes | very |
T358 | 271-274 | JJ | denotes | few |
T359 | 275-282 | NNS | denotes | reports |
T360 | 283-293 | VBG | denotes | describing |
T361 | 294-301 | NN | denotes | species |
T362 | 302-310 | JJ | denotes | specific |
T363 | 301-302 | HYPH | denotes | - |
T364 | 318-326 | NNS | denotes | variants |
T365 | 311-317 | NN | denotes | splice |
T366 | 326-327 | . | denotes | . |
T367 | 327-562 | sentence | denotes | While identification of Mcoln1 is crucial to the development of mouse models for MLIV, the fact that there are two transcripts in mice suggests an additional or alternate function of the gene that may complicate phenotypic assessment. |
T368 | 328-333 | IN | denotes | While |
T369 | 359-361 | VBZ | denotes | is |
T370 | 334-348 | NN | denotes | identification |
T371 | 349-351 | IN | denotes | of |
T372 | 352-358 | NN | denotes | Mcoln1 |
T373 | 463-471 | VBZ | denotes | suggests |
T374 | 362-369 | JJ | denotes | crucial |
T375 | 370-372 | IN | denotes | to |
T376 | 373-376 | DT | denotes | the |
T377 | 377-388 | NN | denotes | development |
T378 | 389-391 | IN | denotes | of |
T379 | 392-397 | NN | denotes | mouse |
T380 | 398-404 | NNS | denotes | models |
T381 | 405-408 | IN | denotes | for |
T382 | 409-413 | NN | denotes | MLIV |
T383 | 413-415 | , | denotes | , |
T384 | 415-418 | DT | denotes | the |
T385 | 419-423 | NN | denotes | fact |
T386 | 424-428 | IN | denotes | that |
T387 | 435-438 | VBP | denotes | are |
T388 | 429-434 | EX | denotes | there |
T389 | 439-442 | CD | denotes | two |
T390 | 443-454 | NNS | denotes | transcripts |
T391 | 455-457 | IN | denotes | in |
T392 | 458-462 | NNS | denotes | mice |
T393 | 472-474 | DT | denotes | an |
T394 | 499-507 | NN | denotes | function |
T395 | 475-485 | JJ | denotes | additional |
T396 | 486-488 | CC | denotes | or |
T397 | 489-498 | JJ | denotes | alternate |
T398 | 508-510 | IN | denotes | of |
T399 | 511-514 | DT | denotes | the |
T400 | 515-519 | NN | denotes | gene |
T401 | 520-524 | WDT | denotes | that |
T402 | 529-539 | VB | denotes | complicate |
T403 | 525-528 | MD | denotes | may |
T404 | 540-550 | JJ | denotes | phenotypic |
T405 | 551-561 | NN | denotes | assessment |
T406 | 561-562 | . | denotes | . |
R173 | T308 | T309 | nsubj | Mcoln1,is |
R174 | T310 | T311 | advmod | highly,similar |
R175 | T311 | T309 | acomp | similar,is |
R176 | T312 | T311 | prep | to,similar |
R177 | T313 | T312 | pobj | MCOLN1,to |
R178 | T314 | T309 | punct | ", ",is |
R179 | T315 | T316 | advmod | especially,in |
R180 | T316 | T309 | prep | in,is |
R181 | T317 | T318 | det | the,domains |
R182 | T318 | T316 | pobj | domains,in |
R183 | T319 | T318 | compound | transmembrane,domains |
R184 | T320 | T318 | cc | and,domains |
R185 | T321 | T322 | compound | ion,pore |
R186 | T322 | T323 | compound | pore,region |
R187 | T323 | T318 | conj | region,domains |
R188 | T324 | T309 | punct | .,is |
R189 | T326 | T327 | advmod | Also,conserved |
R190 | T328 | T327 | punct | ", ",conserved |
R191 | T329 | T330 | det | the,signal |
R192 | T330 | T327 | nsubjpass | signal,conserved |
R193 | T331 | T330 | amod | late,signal |
R194 | T332 | T333 | amod | endosomal,lysosomal |
R195 | T333 | T330 | amod | lysosomal,signal |
R196 | T334 | T333 | punct | /,lysosomal |
R197 | T335 | T330 | compound | targeting,signal |
R198 | T336 | T327 | auxpass | is,conserved |
R199 | T337 | T327 | punct | ", ",conserved |
R200 | T338 | T327 | advcl | supporting,conserved |
R201 | T339 | T340 | det | the,hypothesis |
R202 | T340 | T338 | dobj | hypothesis,supporting |
R203 | T341 | T342 | mark | that,localized |
R205 | T343 | T344 | det | the,protein |
R206 | T344 | T342 | nsubjpass | protein,localized |
R207 | T345 | T342 | auxpass | is,localized |
R208 | T346 | T342 | prep | to,localized |
R209 | T347 | T348 | det | these,membranes |
R210 | T348 | T346 | pobj | membranes,to |
R211 | T349 | T348 | compound | vesicle,membranes |
R212 | T350 | T327 | punct | .,conserved |
R213 | T352 | T353 | prep | To,are |
R214 | T354 | T352 | pobj | date,To |
R215 | T355 | T353 | punct | ", ",are |
R216 | T356 | T353 | expl | there,are |
R217 | T357 | T358 | advmod | very,few |
R218 | T358 | T359 | amod | few,reports |
R219 | T359 | T353 | attr | reports,are |
R220 | T360 | T359 | acl | describing,reports |
R221 | T361 | T362 | npadvmod | species,specific |
R222 | T362 | T364 | amod | specific,variants |
R223 | T363 | T362 | punct | -,specific |
R224 | T364 | T360 | dobj | variants,describing |
R225 | T365 | T364 | compound | splice,variants |
R226 | T366 | T353 | punct | .,are |
R227 | T368 | T369 | mark | While,is |
R229 | T370 | T369 | nsubj | identification,is |
R230 | T371 | T370 | prep | of,identification |
R231 | T372 | T371 | pobj | Mcoln1,of |
R232 | T374 | T369 | acomp | crucial,is |
R233 | T375 | T374 | prep | to,crucial |
R234 | T376 | T377 | det | the,development |
R235 | T377 | T375 | pobj | development,to |
R236 | T378 | T377 | prep | of,development |
R237 | T379 | T380 | compound | mouse,models |
R238 | T380 | T378 | pobj | models,of |
R239 | T381 | T377 | prep | for,development |
R240 | T382 | T381 | pobj | MLIV,for |
R241 | T383 | T373 | punct | ", ",suggests |
R242 | T384 | T385 | det | the,fact |
R243 | T385 | T373 | nsubj | fact,suggests |
R244 | T386 | T387 | mark | that,are |
R245 | T387 | T385 | acl | are,fact |
R246 | T388 | T387 | expl | there,are |
R247 | T389 | T390 | nummod | two,transcripts |
R248 | T390 | T387 | attr | transcripts,are |
R249 | T391 | T387 | prep | in,are |
R250 | T392 | T391 | pobj | mice,in |
R251 | T393 | T394 | det | an,function |
R253 | T395 | T394 | amod | additional,function |
R254 | T396 | T395 | cc | or,additional |
R255 | T397 | T395 | conj | alternate,additional |
R256 | T398 | T394 | prep | of,function |
R257 | T399 | T400 | det | the,gene |
R258 | T400 | T398 | pobj | gene,of |
R259 | T401 | T402 | dep | that,complicate |
R260 | T402 | T394 | relcl | complicate,function |
R261 | T403 | T402 | aux | may,complicate |
R262 | T404 | T405 | amod | phenotypic,assessment |
R263 | T405 | T402 | dobj | assessment,complicate |
R264 | T406 | T373 | punct | .,suggests |
R204 | T342 | T340 | acl | localized,hypothesis |
R228 | T369 | T373 | advcl | is,suggests |
R252 | T394 | T373 | dobj | function,suggests |
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T97 | 0-6 | PR:000010252 | denotes | Mcoln1 |
T98 | 28-34 | PR:000010252 | denotes | MCOLN1 |
T99 | 59-67 | GO:0016020 | denotes | membrane |
T100 | 68-75 | SO:0000417 | denotes | domains |
T101 | 80-83 | CHEBI:24870 | denotes | ion |
T102 | 107-121 | GO:0005770 | denotes | late endosomal |
T103 | 112-121 | _FRAGMENT | denotes | endosomal |
T104 | 132-148 | SO:0001529 | denotes | targeting signal |
T105 | 122-131 | GO:0005764 | denotes | lysosomal |
T106 | 122-148 | SO:0001530 | denotes | lysosomal targeting signal |
T107 | 228-245 | GO:0012506 | denotes | vesicle membranes |
T108 | 294-301 | NCBITaxon:species | denotes | species |
T109 | 311-317 | GO:0008380 | denotes | splice |
T110 | 352-358 | PR:000010252 | denotes | Mcoln1 |
T111 | 392-397 | NCBITaxon:10088 | denotes | mouse |
T112 | 443-454 | SO:0000673 | denotes | transcripts |
T113 | 458-462 | NCBITaxon:10088 | denotes | mice |
T114 | 515-519 | SO:0000704 | denotes | gene |
R3 | T104 | T103 | _lexicallyChainedTo | targeting signal,endosomal |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T457 | 0-6 | PR_EXT:000010252 | denotes | Mcoln1 |
T458 | 28-34 | PR_EXT:000010252 | denotes | MCOLN1 |
T459 | 59-67 | GO:0016020 | denotes | membrane |
T460 | 68-75 | SO_EXT:0000417 | denotes | domains |
T461 | 80-83 | CHEBI:24870 | denotes | ion |
T462 | 80-88 | GO_EXT:0005216 | denotes | ion pore |
T463 | 107-121 | GO:0005770 | denotes | late endosomal |
T464 | 112-121 | _FRAGMENT | denotes | endosomal |
T465 | 132-148 | SO_EXT:0001529 | denotes | targeting signal |
T466 | 122-131 | GO:0005764 | denotes | lysosomal |
T467 | 122-148 | SO_EXT:0001530 | denotes | lysosomal targeting signal |
T468 | 132-141 | GO_EXT:biological_routing_or_transport | denotes | targeting |
T469 | 152-161 | SO_EXT:biological_conservation_process_or_quality | denotes | conserved |
T470 | 198-205 | CHEBI_PR_EXT:protein | denotes | protein |
T471 | 209-218 | GO_PATO_EXT:biological_localization_process_or_quality | denotes | localized |
T472 | 228-245 | GO:0012506 | denotes | vesicle membranes |
T473 | 294-301 | NCBITaxon:species | denotes | species |
T474 | 311-317 | GO:0008380 | denotes | splice |
T475 | 311-326 | SO_EXT:alternative_splice_variant | denotes | splice variants |
T476 | 352-358 | PR_EXT:000010252 | denotes | Mcoln1 |
T477 | 392-397 | NCBITaxon:10088 | denotes | mouse |
T478 | 443-454 | SO_EXT:0000673 | denotes | transcripts |
T479 | 458-462 | NCBITaxon:10088 | denotes | mice |
T480 | 515-519 | SO_EXT:0000704 | denotes | gene |
R267 | T465 | T464 | _lexicallyChainedTo | targeting signal,endosomal |