PMC:7890668 / 4644-5315 JSONTXT

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{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/7890668","sourcedb":"PMC","sourceid":"7890668","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7890668","text":"We applied COVID-KOP to identify possible mechanistic connections between linagliptin and COVID-19 that would support its expected therapeutic effect or identify possible side effects. Using the COVID-KOP user interface, a query is constructed as follows. Individual nodes are placed and linked to specific biomedical objects (such as node n2 being a gene in Fig. 1A). The user can then link these nodes together in any order. In this case study, node n0 is matched to COVID-19; n1 is marked as any phenotypic feature linked to COVID-19; and n2 is any gene related to a phenotypic feature connected to COVID-19. Finally, n2 must also have a connection to the linagliptin.","tracks":[]}