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PMC:7799377 / 6838-8615 JSONTXT

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LitCovid-sentences

Id Subject Object Predicate Lexical cue
T51 0-261 Sentence denotes The viruses associated with both SARS and COVID-19 enter the brain via a process involving the angiotensin-converting enzyme (ACE)-2 receptors located in the CNS [17–19], unlike the MERS virus, which gains entry via the plasma membrane or in the endosomes [20].
T52 262-377 Sentence denotes ACE-2 receptors are expressed in many parts of the body and are particularly densely expressed in the nasal mucosa.
T53 378-582 Sentence denotes Coronaviruses that enter the body via the nasal mucosa may disrupt the nasal endothelium, cross the epithelial barrier, and then directly enter the lymphatic or circulatory system, accessing the CNS [21].
T54 583-691 Sentence denotes The SARS-CoV has been detected in the brain, and it is thought entry occurred by way of the olfactory nerve.
T55 692-878 Sentence denotes Since there have been studies that located the SARS-CoV virus in the CNS but not the lung, it suggests that there is a direct pathway from the olfactory point of entry into the CNS [22].
T56 879-1144 Sentence denotes Alternatively, a high viral load in the brain following a pulmonary infection might mean the virus entered the brain from the respiratory system; e.g., the vagus nerve links the respiratory system to the nucleus ambiguous and solitary tract nuclei of the brainstem.
T57 1145-1308 Sentence denotes It has been speculated that the cardiorespiratory center of the brain may be involved in the severe acute respiratory distress in some patients with COVID-19 [23].
T58 1309-1547 Sentence denotes The more common form of respiratory failure in COVID-19 patients is Type 1 (gas exchange dysfunction resulting in hypoxia and low levels of carbon dioxide), which is more likely to be associated with pneumonia than brain dysfunction [24].
T59 1548-1777 Sentence denotes Type 2 respiratory failure, which involves both hypoxia and high levels of carbon dioxide due to ventilatory failure would be more suggestive of neurological dysfunction, and this occurs less frequently in COVID-19 patients [25].

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T10 937-956 Phenotype denotes pulmonary infection http://purl.obolibrary.org/obo/HP_0006532
T11 1251-1271 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T12 1333-1352 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T13 1423-1430 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T14 1509-1518 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T15 1555-1574 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T16 1596-1603 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
255 182-192 Species denotes MERS virus Tax:1335626
256 378-391 Species denotes Coronaviruses Tax:11118
257 587-595 Species denotes SARS-CoV Tax:694009
258 739-747 Species denotes SARS-CoV Tax:694009
259 1280-1288 Species denotes patients Tax:9606
260 1365-1373 Species denotes patients Tax:9606
261 1763-1771 Species denotes patients Tax:9606
262 1005-1016 Species denotes respiratory Tax:12814
263 1057-1068 Species denotes respiratory Tax:12814
264 1449-1463 Chemical denotes carbon dioxide MESH:D002245
265 1623-1637 Chemical denotes carbon dioxide MESH:D002245
266 42-50 Disease denotes COVID-19 MESH:C000657245
267 937-956 Disease denotes pulmonary infection MESH:D012141
268 1251-1271 Disease denotes respiratory distress MESH:D012128
269 1294-1302 Disease denotes COVID-19 MESH:C000657245
270 1333-1352 Disease denotes respiratory failure MESH:D012131
271 1356-1364 Disease denotes COVID-19 MESH:C000657245
272 1423-1430 Disease denotes hypoxia MESH:D000860
273 1509-1518 Disease denotes pneumonia MESH:D011014
274 1524-1541 Disease denotes brain dysfunction MESH:D001927
275 1555-1574 Disease denotes respiratory failure MESH:D012131
276 1596-1603 Disease denotes hypoxia MESH:D000860
277 1645-1664 Disease denotes ventilatory failure MESH:D012131
278 1693-1717 Disease denotes neurological dysfunction MESH:D009422
279 1754-1762 Disease denotes COVID-19 MESH:C000657245