PMC:7796152 / 9575-11304 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"195","span":{"begin":785,"end":788},"obj":"Gene"},{"id":"196","span":{"begin":392,"end":395},"obj":"Gene"},{"id":"197","span":{"begin":40,"end":48},"obj":"Disease"},{"id":"198","span":{"begin":298,"end":306},"obj":"Disease"},{"id":"199","span":{"begin":682,"end":692},"obj":"Disease"},{"id":"200","span":{"begin":694,"end":701},"obj":"Disease"},{"id":"201","span":{"begin":727,"end":736},"obj":"Disease"},{"id":"208","span":{"begin":1176,"end":1179},"obj":"Gene"},{"id":"209","span":{"begin":920,"end":923},"obj":"Gene"},{"id":"210","span":{"begin":954,"end":962},"obj":"Disease"},{"id":"211","span":{"begin":1099,"end":1118},"obj":"Disease"},{"id":"212","span":{"begin":1123,"end":1135},"obj":"Disease"},{"id":"213","span":{"begin":1203,"end":1211},"obj":"Disease"},{"id":"215","span":{"begin":1365,"end":1368},"obj":"Gene"},{"id":"217","span":{"begin":1444,"end":1447},"obj":"Gene"},{"id":"223","span":{"begin":1537,"end":1540},"obj":"Gene"},{"id":"224","span":{"begin":1563,"end":1582},"obj":"Disease"},{"id":"225","span":{"begin":1587,"end":1599},"obj":"Disease"},{"id":"226","span":{"begin":1692,"end":1711},"obj":"Disease"},{"id":"227","span":{"begin":1716,"end":1728},"obj":"Disease"}],"attributes":[{"id":"A195","pred":"tao:has_database_id","subj":"195","obj":"Gene:5973"},{"id":"A196","pred":"tao:has_database_id","subj":"196","obj":"Gene:5973"},{"id":"A197","pred":"tao:has_database_id","subj":"197","obj":"MESH:C000657245"},{"id":"A198","pred":"tao:has_database_id","subj":"198","obj":"MESH:C000657245"},{"id":"A199","pred":"tao:has_database_id","subj":"199","obj":"MESH:D000275"},{"id":"A200","pred":"tao:has_database_id","subj":"200","obj":"MESH:D001007"},{"id":"A201","pred":"tao:has_database_id","subj":"201","obj":"MESH:D003643"},{"id":"A208","pred":"tao:has_database_id","subj":"208","obj":"Gene:5973"},{"id":"A209","pred":"tao:has_database_id","subj":"209","obj":"Gene:5973"},{"id":"A210","pred":"tao:has_database_id","subj":"210","obj":"MESH:C000657245"},{"id":"A211","pred":"tao:has_database_id","subj":"211","obj":"MESH:D000275"},{"id":"A212","pred":"tao:has_database_id","subj":"212","obj":"MESH:D044342"},{"id":"A213","pred":"tao:has_database_id","subj":"213","obj":"MESH:C000657245"},{"id":"A215","pred":"tao:has_database_id","subj":"215","obj":"Gene:5973"},{"id":"A217","pred":"tao:has_database_id","subj":"217","obj":"Gene:5973"},{"id":"A223","pred":"tao:has_database_id","subj":"223","obj":"Gene:5973"},{"id":"A224","pred":"tao:has_database_id","subj":"224","obj":"MESH:D000275"},{"id":"A225","pred":"tao:has_database_id","subj":"225","obj":"MESH:D044342"},{"id":"A226","pred":"tao:has_database_id","subj":"226","obj":"MESH:D000275"},{"id":"A227","pred":"tao:has_database_id","subj":"227","obj":"MESH:D044342"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"2. The Current Study\nIn response to the COVID-19 pandemic that began in 2019, a policy of social distancing was initiated worldwide. Although circumstances necessitate such extreme measures, social isolation presents a risk for adverse health effects [59]. Older adults who are at greater risk for COVID-19 health complications are likely to remain in strict self-isolation longer than other age groups; therefore, the effects of isolation and ensuing loneliness may be especially severe for them [60]. Loneliness reflects subjective distress resulting from a discrepancy between desired and perceived social relationships. Unfortunately, it causes a host of poor outcomes, such as depression, anxiety, physical morbidity, and mortality, and might also correlate with older subjective age, which is associated with further health risks [4].\nThe current study assessed the status of feelings of loneliness and subjective age among older adults during the COVID-19 pandemic. We identified the factors underlying the association between the two and explored the role of two potential mediating factors—depressive symptoms and malnutrition. The study also explored how subjective age is changing during the COVID-19 pandemic.\nIn light of the literature reviewed, we posited three hypotheses:In comparison with the period before the pandemic, older adults feel older in age during the pandemic.\nFeelings of loneliness are associated with subjective age during times of crisis.\nFeelings of loneliness are indirectly associated with subjective age during crises through depressive symptoms and malnutrition; lonely older adults feel older during crises, and this is associated with higher levels of depressive symptoms and malnutrition."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T31","span":{"begin":682,"end":692},"obj":"Phenotype"},{"id":"T32","span":{"begin":694,"end":701},"obj":"Phenotype"},{"id":"T33","span":{"begin":1123,"end":1135},"obj":"Phenotype"},{"id":"T34","span":{"begin":1587,"end":1599},"obj":"Phenotype"},{"id":"T35","span":{"begin":1716,"end":1728},"obj":"Phenotype"}],"attributes":[{"id":"A31","pred":"hp_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/HP_0000716"},{"id":"A32","pred":"hp_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/HP_0000739"},{"id":"A33","pred":"hp_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/HP_0004395"},{"id":"A34","pred":"hp_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/HP_0004395"},{"id":"A35","pred":"hp_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/HP_0004395"}],"text":"2. The Current Study\nIn response to the COVID-19 pandemic that began in 2019, a policy of social distancing was initiated worldwide. Although circumstances necessitate such extreme measures, social isolation presents a risk for adverse health effects [59]. Older adults who are at greater risk for COVID-19 health complications are likely to remain in strict self-isolation longer than other age groups; therefore, the effects of isolation and ensuing loneliness may be especially severe for them [60]. Loneliness reflects subjective distress resulting from a discrepancy between desired and perceived social relationships. Unfortunately, it causes a host of poor outcomes, such as depression, anxiety, physical morbidity, and mortality, and might also correlate with older subjective age, which is associated with further health risks [4].\nThe current study assessed the status of feelings of loneliness and subjective age among older adults during the COVID-19 pandemic. We identified the factors underlying the association between the two and explored the role of two potential mediating factors—depressive symptoms and malnutrition. The study also explored how subjective age is changing during the COVID-19 pandemic.\nIn light of the literature reviewed, we posited three hypotheses:In comparison with the period before the pandemic, older adults feel older in age during the pandemic.\nFeelings of loneliness are associated with subjective age during times of crisis.\nFeelings of loneliness are indirectly associated with subjective age during crises through depressive symptoms and malnutrition; lonely older adults feel older during crises, and this is associated with higher levels of depressive symptoms and malnutrition."}

{"project":"LitCovid-sentences","denotations":[{"id":"T71","span":{"begin":0,"end":2},"obj":"Sentence"},{"id":"T72","span":{"begin":3,"end":20},"obj":"Sentence"},{"id":"T73","span":{"begin":21,"end":132},"obj":"Sentence"},{"id":"T74","span":{"begin":133,"end":256},"obj":"Sentence"},{"id":"T75","span":{"begin":257,"end":502},"obj":"Sentence"},{"id":"T76","span":{"begin":503,"end":623},"obj":"Sentence"},{"id":"T77","span":{"begin":624,"end":840},"obj":"Sentence"},{"id":"T78","span":{"begin":841,"end":972},"obj":"Sentence"},{"id":"T79","span":{"begin":973,"end":1136},"obj":"Sentence"},{"id":"T80","span":{"begin":1137,"end":1221},"obj":"Sentence"},{"id":"T81","span":{"begin":1222,"end":1389},"obj":"Sentence"},{"id":"T82","span":{"begin":1390,"end":1471},"obj":"Sentence"},{"id":"T83","span":{"begin":1472,"end":1729},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"2. The Current Study\nIn response to the COVID-19 pandemic that began in 2019, a policy of social distancing was initiated worldwide. Although circumstances necessitate such extreme measures, social isolation presents a risk for adverse health effects [59]. Older adults who are at greater risk for COVID-19 health complications are likely to remain in strict self-isolation longer than other age groups; therefore, the effects of isolation and ensuing loneliness may be especially severe for them [60]. Loneliness reflects subjective distress resulting from a discrepancy between desired and perceived social relationships. Unfortunately, it causes a host of poor outcomes, such as depression, anxiety, physical morbidity, and mortality, and might also correlate with older subjective age, which is associated with further health risks [4].\nThe current study assessed the status of feelings of loneliness and subjective age among older adults during the COVID-19 pandemic. We identified the factors underlying the association between the two and explored the role of two potential mediating factors—depressive symptoms and malnutrition. The study also explored how subjective age is changing during the COVID-19 pandemic.\nIn light of the literature reviewed, we posited three hypotheses:In comparison with the period before the pandemic, older adults feel older in age during the pandemic.\nFeelings of loneliness are associated with subjective age during times of crisis.\nFeelings of loneliness are indirectly associated with subjective age during crises through depressive symptoms and malnutrition; lonely older adults feel older during crises, and this is associated with higher levels of depressive symptoms and malnutrition."}