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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2 50-53 Gene denotes Age Gene:5973
3 80-88 Disease denotes COVID-19 MESH:C000657245
21 1024-1027 Gene denotes age Gene:5973
22 726-729 Gene denotes age Gene:5973
23 649-652 Gene denotes age Gene:5973
24 359-362 Gene denotes age Gene:5973
25 247-250 Gene denotes age Gene:5973
26 838-850 Species denotes participants Tax:9606
27 196-215 Disease denotes depressive symptoms MESH:D000275
28 220-232 Disease denotes malnutrition MESH:D044342
29 286-294 Disease denotes COVID-19 MESH:C000657245
30 534-553 Disease denotes depressive symptoms MESH:D000275
31 558-570 Disease denotes malnutrition MESH:D044342
32 741-749 Disease denotes COVID-19 MESH:C000657245
33 775-787 Disease denotes malnutrition MESH:D044342
34 800-819 Disease denotes depressive symptoms MESH:D000275
35 873-881 Disease denotes COVID-19 MESH:C000657245
36 995-1007 Disease denotes malnutrition MESH:D044342
37 1674-1686 Disease denotes malnutrition MESH:D044342
39 1722-1725 Gene denotes Age Gene:5973
56 2810-2813 Gene denotes age Gene:5973
57 2659-2662 Gene denotes age Gene:5973
58 2427-2430 Gene denotes age Gene:5973
59 2249-2252 Gene denotes age Gene:5973
60 2192-2195 Gene denotes age Gene:5973
61 2054-2057 Gene denotes age Gene:5973
62 1994-1997 Gene denotes age Gene:5973
63 1885-1888 Gene denotes age Gene:5973
64 1869-1872 Gene denotes age Gene:5973
65 1841-1844 Gene denotes age Gene:5973
66 1753-1756 Gene denotes age Gene:5973
67 1787-1793 Species denotes people Tax:9606
68 1945-1951 Species denotes People Tax:9606
69 2569-2588 Disease denotes depressive symptoms MESH:D000275
70 3032-3042 Disease denotes depression MESH:D000275
71 3072-3082 Disease denotes depression MESH:D000275
80 3597-3600 Gene denotes age Gene:5973
81 3510-3513 Gene denotes age Gene:5973
82 3409-3412 Gene denotes age Gene:5973
83 3293-3296 Gene denotes age Gene:5973
84 3151-3154 Gene denotes age Gene:5973
85 3115-3120 Species denotes women Tax:9606
86 3184-3187 Species denotes men Tax:9606
87 3249-3254 Species denotes woman Tax:9606
89 3760-3763 Gene denotes age Gene:5973
97 4811-4814 Gene denotes age Gene:5973
98 4724-4727 Gene denotes age Gene:5973
99 4619-4622 Gene denotes age Gene:5973
100 4759-4764 Species denotes women Tax:9606
101 4234-4243 Disease denotes mortality MESH:D003643
102 4360-4383 Disease denotes cardiovascular diseases MESH:D002318
103 4432-4450 Disease denotes impaired cognition MESH:D003072
107 5437-5440 Gene denotes age Gene:5973
108 5325-5328 Gene denotes age Gene:5973
109 5578-5583 Disease denotes death MESH:D003643
116 6021-6024 Gene denotes age Gene:5973
117 5784-5787 Gene denotes age Gene:5973
118 5814-5833 Disease denotes Coronavirus disease MESH:D018352
119 5835-5843 Disease denotes COVID-19 MESH:C000657245
120 6090-6109 Disease denotes depressive symptoms MESH:D000275
121 6114-6126 Disease denotes malnutrition MESH:D044342
123 6136-6155 Disease denotes Depressive Symptoms MESH:D000275
134 6973-6976 Gene denotes age Gene:5973
135 6217-6234 Disease denotes Burden of Disease MESH:D003141
136 6242-6252 Disease denotes depression MESH:D000275
137 6376-6386 Disease denotes depression MESH:D000275
138 6524-6534 Disease denotes depression MESH:D000275
139 6776-6786 Disease denotes depression MESH:D000275
140 6860-6879 Disease denotes depressive symptoms MESH:D000275
141 6943-6964 Disease denotes cognitive impairments MESH:D003072
142 7008-7022 Disease denotes mental illness MESH:D002908
143 7035-7044 Disease denotes depressed MESH:D000275
153 7757-7760 Gene denotes age Gene:5973
154 7646-7649 Gene denotes age Gene:5973
155 7474-7477 Gene denotes age Gene:5973
156 7597-7603 Species denotes people Tax:9606
157 7082-7092 Disease denotes Depression MESH:D000275
158 7180-7197 Disease denotes cognitive decline MESH:D003072
159 7347-7357 Disease denotes depression MESH:D000275
160 7791-7797 Disease denotes stress MESH:D000079225
161 7809-7828 Disease denotes depressive symptoms MESH:D000275
169 8171-8174 Gene denotes age Gene:5973
170 7941-7951 Disease denotes deficiency MESH:D007153
171 8213-8225 Disease denotes malnutrition MESH:D044342
172 8304-8316 Disease denotes malnutrition MESH:D044342
173 8489-8507 Disease denotes sensory impairment MESH:D012678
174 8613-8625 Disease denotes inflammation MESH:D007249
175 8676-8702 Disease denotes loss of vision and hearing MESH:D054062
182 9564-9567 Gene denotes age Gene:5973
183 9520-9523 Gene denotes age Gene:5973
184 8824-8834 Disease denotes depression MESH:D000275
185 8914-8934 Disease denotes cognitive impairment MESH:D003072
186 9438-9450 Disease denotes malnutrition MESH:D044342
187 9469-9481 Disease denotes malnutrition MESH:D044342
195 10360-10363 Gene denotes age Gene:5973
196 9967-9970 Gene denotes age Gene:5973
197 9615-9623 Disease denotes COVID-19 MESH:C000657245
198 9873-9881 Disease denotes COVID-19 MESH:C000657245
199 10257-10267 Disease denotes depression MESH:D000275
200 10269-10276 Disease denotes anxiety MESH:D001007
201 10302-10311 Disease denotes mortality MESH:D003643
208 10751-10754 Gene denotes age Gene:5973
209 10495-10498 Gene denotes age Gene:5973
210 10529-10537 Disease denotes COVID-19 MESH:C000657245
211 10674-10693 Disease denotes depressive symptoms MESH:D000275
212 10698-10710 Disease denotes malnutrition MESH:D044342
213 10778-10786 Disease denotes COVID-19 MESH:C000657245
215 10940-10943 Gene denotes age Gene:5973
217 11019-11022 Gene denotes age Gene:5973
223 11112-11115 Gene denotes age Gene:5973
224 11138-11157 Disease denotes depressive symptoms MESH:D000275
225 11162-11174 Disease denotes malnutrition MESH:D044342
226 11267-11286 Disease denotes depressive symptoms MESH:D000275
227 11291-11303 Disease denotes malnutrition MESH:D044342
229 11546-11549 Gene denotes age Gene:5973
232 12160-12172 Species denotes participants Tax:9606
233 12229-12241 Species denotes participants Tax:9606
236 12546-12549 Gene denotes Age Gene:5973
237 12571-12579 Disease denotes COVID-19 MESH:C000657245
243 12792-12795 Gene denotes age Gene:5973
244 12758-12761 Gene denotes age Gene:5973
245 12602-12605 Gene denotes age Gene:5973
246 12801-12813 Species denotes participants Tax:9606
247 12857-12865 Disease denotes COVID-19 MESH:C000657245
249 12933-12952 Disease denotes Depressive Symptoms MESH:D000275
253 12953-12972 Disease denotes Depressive symptoms MESH:D000275
254 13013-13023 Disease denotes Depression MESH:D000275
255 13140-13159 Disease denotes depressive symptoms MESH:D000275
259 13592-13595 Gene denotes Age Gene:5973
260 13497-13505 Disease denotes Diabetes MESH:D003920
261 13631-13643 Disease denotes malnutrition MESH:D044342
263 13854-13857 Gene denotes age Gene:5973
267 14793-14796 Gene denotes age Gene:5973
268 14622-14625 Gene denotes age Gene:5973
269 14648-14656 Disease denotes COVID-19 MESH:C000657245
275 15453-15456 Gene denotes age Gene:5973
276 15050-15069 Disease denotes depressive symptoms MESH:D000275
277 15074-15086 Disease denotes malnutrition MESH:D044342
278 15486-15505 Disease denotes depressive symptoms MESH:D000275
279 15510-15522 Disease denotes malnutrition MESH:D044342
282 16557-16569 Species denotes participants Tax:9606
283 16575-16580 Species denotes women Tax:9606
289 17110-17113 Gene denotes age Gene:5973
290 16932-16944 Species denotes participants Tax:9606
291 16981-16991 Disease denotes depressive MESH:D000275
292 17041-17053 Disease denotes malnutrition MESH:D044342
293 17125-17133 Disease denotes COVID-19 MESH:C000657245
295 17309-17321 Species denotes participants Tax:9606
300 17692-17695 Gene denotes age Gene:5973
301 17589-17592 Gene denotes age Gene:5973
302 17468-17471 Gene denotes age Gene:5973
303 17483-17491 Disease denotes COVID-19 MESH:C000657245
307 17936-17939 Gene denotes age Gene:5973
308 17860-17879 Disease denotes depressive symptoms MESH:D000275
309 17885-17897 Disease denotes malnutrition MESH:D044342
319 18682-18685 Gene denotes age Gene:5973
320 18590-18593 Gene denotes age Gene:5973
321 18417-18420 Gene denotes age Gene:5973
322 18201-18204 Gene denotes age Gene:5973
323 18154-18157 Gene denotes age Gene:5973
324 18213-18232 Disease denotes depressive symptoms MESH:D000275
325 18237-18249 Disease denotes malnutrition MESH:D044342
326 18464-18476 Disease denotes malnutrition MESH:D044342
327 18554-18573 Disease denotes depressive symptoms MESH:D000275
338 19516-19519 Gene denotes age Gene:5973
339 19418-19421 Gene denotes age Gene:5973
340 19283-19286 Gene denotes age Gene:5973
341 19169-19172 Gene denotes age Gene:5973
342 18869-18872 Gene denotes age Gene:5973
343 18854-18860 Species denotes people Tax:9606
344 18748-18756 Disease denotes COVID-19 MESH:C000657245
345 19184-19192 Disease denotes COVID-19 MESH:C000657245
346 19295-19314 Disease denotes depressive symptoms MESH:D000275
347 19319-19331 Disease denotes malnutrition MESH:D044342
360 20180-20183 Gene denotes age Gene:5973
361 19934-19937 Gene denotes age Gene:5973
362 19796-19799 Gene denotes age Gene:5973
363 19606-19609 Gene denotes age Gene:5973
364 19834-19840 Disease denotes stress MESH:D000079225
365 19923-19929 Disease denotes stress MESH:D000079225
366 19969-19975 Disease denotes stress MESH:D000079225
367 20068-20092 Disease denotes immunological impairment MESH:D007153
368 20097-20103 Disease denotes stress MESH:D000079225
369 20215-20221 Disease denotes stress MESH:D000079225
370 20329-20339 Disease denotes irritation MESH:D001523
371 20385-20391 Disease denotes stress MESH:D000079225
382 21541-21544 Gene denotes age Gene:5973
383 21287-21290 Gene denotes age Gene:5973
384 21140-21143 Gene denotes age Gene:5973
385 21050-21053 Gene denotes age Gene:5973
386 20955-20958 Gene denotes age Gene:5973
387 20735-20738 Gene denotes age Gene:5973
388 20667-20670 Gene denotes age Gene:5973
389 20689-20701 Species denotes participants Tax:9606
390 21569-21581 Disease denotes malnutrition MESH:D044342
391 21591-21610 Disease denotes depressive symptoms MESH:D000275
404 23374-23377 Gene denotes age Gene:5973
405 23115-23118 Gene denotes age Gene:5973
406 22795-22798 Gene denotes age Gene:5973
407 22685-22688 Gene denotes age Gene:5973
408 21989-21992 Gene denotes age Gene:5973
409 21682-21694 Disease denotes malnutrition MESH:D044342
410 22086-22098 Disease denotes malnutrition MESH:D044342
411 22454-22461 Disease denotes falling MESH:D002303
412 22475-22482 Disease denotes falling MESH:D002303
413 22657-22669 Disease denotes malnutrition MESH:D044342
414 23207-23219 Disease denotes malnutrition MESH:D044342
415 23346-23358 Disease denotes malnutrition MESH:D044342
422 23634-23637 Gene denotes age Gene:5973
423 23546-23549 Gene denotes age Gene:5973
424 24532-24538 Species denotes people Tax:9606
425 23518-23530 Disease denotes malnutrition MESH:D044342
426 23606-23618 Disease denotes malnutrition MESH:D044342
427 24450-24458 Disease denotes Covid-19 MESH:C000657245
431 24994-24997 Gene denotes age Gene:5973
432 24873-24876 Gene denotes age Gene:5973
433 25516-25521 Species denotes human Tax:9606
436 25933-25936 Gene denotes age Gene:5973
437 25904-25916 Disease denotes malnutrition MESH:D044342
440 26858-26861 Gene denotes age Gene:5973
441 26829-26841 Disease denotes malnutrition MESH:D044342
447 27002-27013 Species denotes participant Tax:9606
448 27117-27137 Disease denotes address malnutrition MESH:D044342
449 27180-27187 Disease denotes hearing MESH:D034381
450 27375-27383 Disease denotes COVID-19 MESH:C000657245
451 27497-27514 Disease denotes hearing abilities MESH:D034381
455 27891-27894 Gene denotes APC Gene:324
456 27909-27912 Gene denotes Tel Gene:2120
457 27836-27839 Gene denotes Tel Gene:2120
459 28097-28100 Gene denotes Tel Gene:2120
583 28713-28716 Gene denotes age Gene:5973
584 28642-28645 Gene denotes age Gene:5973
585 28534-28537 Gene denotes age Gene:5973
590 29335-29338 Gene denotes age Gene:5973
591 29043-29046 Gene denotes Age Gene:5973
592 29234-29253 Disease denotes Depressive symptoms MESH:D000275
593 29346-29354 Disease denotes COVID-19 MESH:C000657245
595 29387-29406 Disease denotes Coronavirus disease MESH:D018352
600 29499-29502 Gene denotes age Gene:5973
601 29451-29454 Gene denotes age Gene:5973
602 29466-29474 Disease denotes COVID-19 MESH:C000657245
603 29514-29522 Disease denotes COVID-19 MESH:C000657245
608 29650-29653 Gene denotes age Gene:5973
609 29586-29589 Gene denotes age Gene:5973
610 29597-29605 Disease denotes COVID-19 MESH:C000657245
611 29661-29669 Disease denotes COVID-19 MESH:C000657245
614 29829-29832 Gene denotes age Gene:5973
615 29840-29848 Disease denotes COVID-19 MESH:C000657245
620 30037-30040 Gene denotes Age Gene:5973
621 29891-29894 Gene denotes Age Gene:5973
622 29906-29914 Disease denotes COVID-19 MESH:C000657245
623 30247-30266 Disease denotes Depressive symptoms MESH:D000275
628 30763-30766 Gene denotes age Gene:5973
629 30699-30702 Gene denotes Age Gene:5973
630 30731-30750 Disease denotes Depressive symptoms MESH:D000275
631 30774-30782 Disease denotes COVID-19 MESH:C000657245
634 31082-31085 Gene denotes Age Gene:5973
635 31021-31033 Species denotes M = mediator Tax:375433

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 12-24 Phenotype denotes Malnutrition http://purl.obolibrary.org/obo/HP_0004395
T2 220-232 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T3 558-570 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T4 775-787 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T5 995-1007 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T6 1674-1686 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T7 3032-3042 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T8 3072-3082 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T9 4360-4383 Phenotype denotes cardiovascular diseases http://purl.obolibrary.org/obo/HP_0001626
T10 6114-6126 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T11 6242-6252 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T12 6376-6386 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T13 6524-6534 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T14 6776-6786 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T15 6943-6964 Phenotype denotes cognitive impairments http://purl.obolibrary.org/obo/HP_0100543
T16 7082-7092 Phenotype denotes Depression http://purl.obolibrary.org/obo/HP_0000716
T17 7180-7197 Phenotype denotes cognitive decline http://purl.obolibrary.org/obo/HP_0001268
T18 7347-7357 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T19 7882-7894 Phenotype denotes Malnutrition http://purl.obolibrary.org/obo/HP_0004395
T20 7895-7907 Phenotype denotes Malnutrition http://purl.obolibrary.org/obo/HP_0004395
T21 8213-8225 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T22 8304-8316 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T23 8489-8507 Phenotype denotes sensory impairment http://purl.obolibrary.org/obo/HP_0003474
T24 8565-8580 Phenotype denotes dental problems http://purl.obolibrary.org/obo/HP_0000164
T25 8593-8611 Phenotype denotes difficulty chewing http://purl.obolibrary.org/obo/HP_0005216
T26 8664-8690 Phenotype denotes Progressive loss of vision http://purl.obolibrary.org/obo/HP_0000529
T27 8824-8834 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T28 8914-8934 Phenotype denotes cognitive impairment http://purl.obolibrary.org/obo/HP_0100543
T29 9438-9450 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T30 9469-9481 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T31 10257-10267 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T32 10269-10276 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T33 10698-10710 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T34 11162-11174 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T35 11291-11303 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T36 13013-13023 Phenotype denotes Depression http://purl.obolibrary.org/obo/HP_0000716
T37 13363-13375 Phenotype denotes Malnutrition http://purl.obolibrary.org/obo/HP_0004395
T38 13376-13388 Phenotype denotes Malnutrition http://purl.obolibrary.org/obo/HP_0004395
T39 13631-13643 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T40 15074-15086 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T41 15510-15522 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T42 16134-16139 Phenotype denotes falls http://purl.obolibrary.org/obo/HP_0002527
T43 17041-17053 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T44 17885-17897 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T45 18237-18249 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T46 18464-18476 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T47 19319-19331 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T48 21569-21581 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T49 21682-21694 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T50 22086-22098 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T51 22274-22292 Phenotype denotes social interaction http://purl.obolibrary.org/obo/HP_0008763
T52 22657-22669 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T53 23207-23219 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T54 23346-23358 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T55 23518-23530 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T56 23606-23618 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T57 25904-25916 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T58 26829-26841 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T59 27125-27137 Phenotype denotes malnutrition http://purl.obolibrary.org/obo/HP_0004395
T60 29273-29285 Phenotype denotes Malnutrition http://purl.obolibrary.org/obo/HP_0004395
T61 30287-30299 Phenotype denotes Malnutrition http://purl.obolibrary.org/obo/HP_0004395
T62 30898-30910 Phenotype denotes Malnutrition http://purl.obolibrary.org/obo/HP_0004395

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-97 Sentence denotes Loneliness, Malnutrition and Change in Subjective Age among Older Adults during COVID-19 Pandemic
T2 99-107 Sentence denotes Abstract
T3 108-119 Sentence denotes Objectives:
T4 120-363 Sentence denotes We examined the effect of loneliness and the role of two mediating factors, depressive symptoms and malnutrition on subjective age among older adults during the 2020 COVID-19 pandemic, and explored how the pandemic is affecting subjective age.
T5 364-371 Sentence denotes Design:
T6 372-446 Sentence denotes A convenience sample of 201 older adults aged 65 and over was interviewed.
T7 447-653 Sentence denotes Using bootstrapping, we tested the strength and significance of the indirect effect of depressive symptoms and malnutrition (mediators) on the relationship between feelings of loneliness and subjective age.
T8 654-662 Sentence denotes Results:
T9 663-820 Sentence denotes The relationship between feelings of loneliness and subjective age during the COVID-19 pandemic was mediated by malnutrition, but not by depressive symptoms.
T10 821-926 Sentence denotes In addition, the participants felt older during the COVID-19 pandemic compared with the preceding period.
T11 927-939 Sentence denotes Conclusions:
T12 940-1028 Sentence denotes An association was found among feelings of loneliness, malnutrition, and subjective age.
T13 1029-1437 Sentence denotes To overcome these feelings in times of crisis like the pandemic, it is essential to develop new communication methods (technologies for managing and addressing the needs of the older population; technologies to encourage social engagement, and technologies for managing and providing remote medical services) for and with older adults that are effective in reducing loneliness, and to promote good nutrition.
T14 1438-1687 Sentence denotes Possible practical solutions include new social network technologies for reducing loneliness combined with continued reliance on phone communication as an intervention of psychological support to promote a healthy lifestyle and prevent malnutrition.
T15 1689-1691 Sentence denotes 1.
T16 1692-1704 Sentence denotes Introduction
T17 1706-1710 Sentence denotes 1.1.
T18 1711-1741 Sentence denotes Subjective Age of Older Adults
T19 1742-1849 Sentence denotes Subjective age refers to the degree to which people feel younger or older than their chronological age [1].
T20 1850-1944 Sentence denotes Like chronological age, subjective age contributes to a variety of developmental outcomes [2].
T21 1945-2071 Sentence denotes People who feel younger than their chronological age are usually better off than those who feel their actual age or older [3].
T22 2072-2357 Sentence denotes For instance, the outcomes of one of the only meta-analyses that has investigated the longitudinal effect of subjective age on future health and longevity among adults (average age 57–85 years) revealed that feeling younger is connected with improved physical health and longevity [4].
T23 2358-2593 Sentence denotes Furthermore, a correlation has been found between younger subjective age and important developmental processes, such as enhanced subjective wellbeing [5], better cognition test performance [6], and having fewer depressive symptoms [7].
T24 2594-2790 Sentence denotes Research has found that feeling younger than one’s chronological age is associated with higher levels of subjective wellbeing [5], greater life satisfaction [8,9], and more positive affect [5,10].
T25 2791-2930 Sentence denotes Younger subjective age is also associated with having a sense of meaning in life, higher levels of optimism, and more successful aging [8].
T26 2931-3088 Sentence denotes Similarly, feeling younger correlates with a decreased likelihood of experiencing a major episode of depression [11] and reduced symptoms of depression [12].
T27 3089-3193 Sentence denotes In another meta-analysis, women reported a younger subjective age compared to that reported by men [13].
T28 3194-3369 Sentence denotes Later studies have provided more evidence that being a woman is correlated with younger subjective age [5,14,15]; however, others have not found this correlation [6,16,17,18].
T29 3370-3606 Sentence denotes The impact of loneliness on subjective age is not clear; one study found that a decrease in loneliness resulted in a decrease in subjective age, but, changes in objective social indicators did not predict changes in subjective age [19].
T30 3608-3612 Sentence denotes 1.2.
T31 3613-3639 Sentence denotes Loneliness in Older Adults
T32 3640-3737 Sentence denotes The definition of loneliness is the gap between real and wished for social relationships [20,21].
T33 3738-3847 Sentence denotes Similar to subjective age, loneliness is a subjective concept and not an objective social manifestation [20].
T34 3848-4103 Sentence denotes Although loneliness can be connected with objective aspects of the social network including the number and frequency of actual social contacts, it is not synonymous with these aspects and it still represents the qualitative elements of relationships [22].
T35 4104-4252 Sentence denotes With a few exceptions, the majority of past research has emphasized the role of loneliness as a strong predictor of morbidity and mortality [23,24].
T36 4253-4496 Sentence denotes A considerable body of research has pointed out that a high level of loneliness is a major risk factor for cardiovascular diseases [25], disability [26], poor sleep hygiene [27], impaired cognition [28], and impaired physical functioning [22].
T37 4497-4851 Sentence denotes These negative effects of loneliness might explain the possible association between feelings of loneliness and subjective age, and in contrast, the negative correlation between size of friendship network and self-perception of age (for example, the finding that women who felt themselves younger than their actual age had larger friendship networks [29].
T38 4852-5069 Sentence denotes Moreover, a recent study suggested a plausible causal model of loneliness leading to morbidity and mortality, and found evidence of mediation by subjective health, depressive symptoms, and functional limitations [30].
T39 5070-5259 Sentence denotes Although objective indicators of social relationships also predict health and well-being [31,32], these are generally thought to exert a somewhat smaller effect in comparison to loneliness.
T40 5260-5353 Sentence denotes However, there is general consent that loneliness increases with age among older adults [33].
T41 5354-5446 Sentence denotes This is not surprising given the many objective losses that take place in advanced age [33].
T42 5447-5678 Sentence denotes Objective losses include, for example, retirement because it is often associated with the narrowing of one’s social network or the death of a spouse, siblings, and close friends, which also result in reduced social contact [34,35].
T43 5680-5684 Sentence denotes 1.3.
T44 5685-5702 Sentence denotes Mediating Factors
T45 5703-6041 Sentence denotes In addition to the possible direct correlation between loneliness and subjective age, during a crisis like the Coronavirus disease (COVID-19) pandemic, feelings of loneliness can have far-reaching implications for the life of older adults, which could shed light on some of the effects of feeling lonely on subjective age during a crisis.
T46 6042-6127 Sentence denotes Two specific mediators are likely to be at play—depressive symptoms and malnutrition.
T47 6129-6135 Sentence denotes 1.3.1.
T48 6136-6155 Sentence denotes Depressive Symptoms
T49 6156-6352 Sentence denotes According to the 2001 World Health Organization (WHO) Global Burden of Disease Study, depression is a serious public health problem among individuals, families, and societies throughout the world.
T50 6353-6514 Sentence denotes The WHO estimated that depression was the fourth leading contributor to the global burden of disease in 2000, as measured by disability-adjusted life years [36].
T51 6515-6740 Sentence denotes Although depression rates are generally lower among older adults (5.4%) compared to middle-aged (9.8%) and younger (7.4%) adults, the rate among seniors in the United States has continued to rise in recent decades [37,38,39].
T52 6741-6843 Sentence denotes In addition, the reported rates of depression in the older population of the US may be underestimated.
T53 6844-7081 Sentence denotes This is because depressive symptoms can be masked as physical complaints or initially appear to be cognitive impairments in this age group, moreover, the stigma of mental illness may inhibit depressed older adults from seeking treatment.
T54 7082-7212 Sentence denotes Depression is one of the negative health outcomes linked to loneliness as well as disability, and cognitive decline [40,41,42,43].
T55 7213-7370 Sentence denotes For example, a study in Ohio retirement communities found that older individuals who reported feeling lonely had significantly higher depression scores [44].
T56 7371-7444 Sentence denotes However, the experiences and consequences of loneliness may vary greatly.
T57 7445-7572 Sentence denotes Moreover, because subjective age reflects self-perception, it is also related to many psychological factors among older adults.
T58 7573-7724 Sentence denotes Research has shown that people who feel younger than their chronological age tend to be mentally healthy and have fewer psychological problems [11,12].
T59 7725-7873 Sentence denotes In addition, younger subjective age has been associated with less stress [1], fewer depressive symptoms [45,46], and strong mastery beliefs [45,47].
T60 7875-7881 Sentence denotes 1.3.2.
T61 7882-7894 Sentence denotes Malnutrition
T62 7895-8146 Sentence denotes Malnutrition is defined as a state in which a deficiency, excess, or imbalance of energy, protein, and other nutrients causes measurable adverse effects on tissue and body form (body shape, size, and composition), function, and clinical outcomes [48].
T63 8147-8196 Sentence denotes It is more prevalent as age increases [49,50,51].
T64 8197-8382 Sentence denotes The etiology of malnutrition is multifactorial; adverse physiological, psychological, and social causes of malnutrition in older adults are consistently reported in the literature [52].
T65 8383-8663 Sentence denotes Aging is accompanied by physiological changes that can negatively impact nutritional status, for example, sensory impairment may result in reduced appetite and poor oral health, and dental problems can lead to difficulty chewing, inflammation, and a monotonous, poor-quality diet.
T66 8664-8793 Sentence denotes Progressive loss of vision and hearing may also limit mobility and affect the ability to shop for food and prepare meals [53,54].
T67 8794-9115 Sentence denotes In addition to loneliness and depression, other psychosocial and social changes characteristic of older adults, such as cognitive impairment, heavy use of medication, periods of lengthy hospitalization, retirement from paid work, bereavement, and increasing frailty can also contribute to poor nutritional status [54,55].
T68 9116-9310 Sentence denotes These factors affect the ability of older adults to meet dietary needs or to digest, absorb, utilize, or excrete nutrients that are ingested, leading to reduced energy intake and lean body mass.
T69 9311-9462 Sentence denotes This, in turn, may result in a reduced metabolic rate, a corresponding decline in total energy expenditure, and potentially to malnutrition [56,57,58].
T70 9463-9573 Sentence denotes Thus, malnutrition, like other unhealthy outcomes of old age, may also be associated with subjective age [45].
T71 9575-9577 Sentence denotes 2.
T72 9578-9595 Sentence denotes The Current Study
T73 9596-9707 Sentence denotes In response to the COVID-19 pandemic that began in 2019, a policy of social distancing was initiated worldwide.
T74 9708-9831 Sentence denotes Although circumstances necessitate such extreme measures, social isolation presents a risk for adverse health effects [59].
T75 9832-10077 Sentence denotes Older adults who are at greater risk for COVID-19 health complications are likely to remain in strict self-isolation longer than other age groups; therefore, the effects of isolation and ensuing loneliness may be especially severe for them [60].
T76 10078-10198 Sentence denotes Loneliness reflects subjective distress resulting from a discrepancy between desired and perceived social relationships.
T77 10199-10415 Sentence denotes Unfortunately, it causes a host of poor outcomes, such as depression, anxiety, physical morbidity, and mortality, and might also correlate with older subjective age, which is associated with further health risks [4].
T78 10416-10547 Sentence denotes The current study assessed the status of feelings of loneliness and subjective age among older adults during the COVID-19 pandemic.
T79 10548-10711 Sentence denotes We identified the factors underlying the association between the two and explored the role of two potential mediating factors—depressive symptoms and malnutrition.
T80 10712-10796 Sentence denotes The study also explored how subjective age is changing during the COVID-19 pandemic.
T81 10797-10964 Sentence denotes In light of the literature reviewed, we posited three hypotheses:In comparison with the period before the pandemic, older adults feel older in age during the pandemic.
T82 10965-11046 Sentence denotes Feelings of loneliness are associated with subjective age during times of crisis.
T83 11047-11304 Sentence denotes Feelings of loneliness are indirectly associated with subjective age during crises through depressive symptoms and malnutrition; lonely older adults feel older during crises, and this is associated with higher levels of depressive symptoms and malnutrition.
T84 11306-11308 Sentence denotes 3.
T85 11309-11315 Sentence denotes Method
T86 11317-11321 Sentence denotes 3.1.
T87 11322-11351 Sentence denotes Study Design and Participants
T88 11352-11521 Sentence denotes This was a cross-sectional study of a convenience sample of 201 older adults aged 65 and over, who represent the two main ethnic groups living in Israel, Jews and Arabs.
T89 11522-11646 Sentence denotes Inclusion criteria were age 65 and over and the ability to speak and understand (but not necessarily read) Hebrew or Arabic.
T90 11647-11679 Sentence denotes The refusal rate was 21 percent.
T91 11681-11685 Sentence denotes 3.2.
T92 11686-11696 Sentence denotes Procedures
T93 11697-11794 Sentence denotes The Research Ethics Committee of the college at which the research took place approved the study.
T94 11795-11923 Sentence denotes Those who agreed to participate received an explanation about the study and their right to withdraw at any time without penalty.
T95 11924-11962 Sentence denotes Strict confidentiality was maintained.
T96 11963-12155 Sentence denotes Professional interviewers collected the data in telephone interviews (in compliance with pandemic-related restrictions), using appropriate translated, validated, and structured questionnaires.
T97 12156-12197 Sentence denotes The participants were recruited randomly.
T98 12198-12242 Sentence denotes The final sample comprised 201 participants:
T99 12243-12266 Sentence denotes 100 Jews and 101 Arabs.
T100 12267-12313 Sentence denotes The data were collected in April and May 2020.
T101 12315-12319 Sentence denotes 3.3.
T102 12320-12328 Sentence denotes Measures
T103 12330-12336 Sentence denotes 3.3.1.
T104 12337-12358 Sentence denotes Independent Variable:
T105 12359-12369 Sentence denotes Loneliness
T106 12370-12506 Sentence denotes Loneliness was measured by a single direct question: “Do you sometimes feel lonely?” with four options: never, seldom, sometimes, often.
T107 12508-12514 Sentence denotes 3.3.2.
T108 12515-12534 Sentence denotes Dependent Variable:
T109 12535-12590 Sentence denotes Subjective Age during a Crisis (the COVID-19 Pandemic).
T110 12591-12796 Sentence denotes Subjective age was measured by two direct questions: “On a scale from 0 to 5, how old do you feel?” The six options were on a scale between 0 = younger than my actual age, and 5 = older than my actual age.
T111 12797-12908 Sentence denotes The participants were asked to refer to the time before the COVID-19 pandemic and the time during the pandemic.
T112 12910-12914 Sentence denotes 3.4.
T113 12915-12924 Sentence denotes Mediators
T114 12926-12932 Sentence denotes 3.4.1.
T115 12933-12952 Sentence denotes Depressive Symptoms
T116 12953-13037 Sentence denotes Depressive symptoms were measured using the GDS (Geriatrics Depression Scale; [61]).
T117 13038-13224 Sentence denotes This questionnaire was chosen because it is a simple and reliable tool that allows the examination of depressive symptoms among older adults without requiring a professional interviewer.
T118 13225-13300 Sentence denotes The instrument is composed of 15 items in a yes (1)/no (2) response format.
T119 13301-13354 Sentence denotes The internal reliability (Cronbach’s alpha) was 0.80.
T120 13356-13362 Sentence denotes 3.4.2.
T121 13363-13375 Sentence denotes Malnutrition
T122 13376-13644 Sentence denotes Malnutrition was measured using the NSI (Determine Nutrition Screening Initiative) instrument, developed by the American Diabetes Association, the American Family Doctors Association, and the National Council of Old Age to detect older adults at risk for malnutrition.
T123 13645-13743 Sentence denotes The questionnaire is composed of 10 items, in a yes (with changing scores)/no (0) response format.
T124 13745-13749 Sentence denotes 3.5.
T125 13750-13760 Sentence denotes Covariates
T126 13761-13961 Sentence denotes We controlled for the socioeconomic variables of gender (dichotomous; 0 = male, 1 = female), age, years of education (both continuous), and marital status (with partner = 1, or without a partner = 0).
T127 13962-14046 Sentence denotes All the instruments were translated into Hebrew and Arabic by bilingual translators.
T128 14047-14097 Sentence denotes The complete questionnaire underwent a pilot test.
T129 14098-14268 Sentence denotes The questionnaire took approximately 15 min to complete, the verbal instructions were comprehensible, and there was no need for further changes prior to administering it.
T130 14270-14274 Sentence denotes 3.6.
T131 14275-14288 Sentence denotes Data Analyses
T132 14289-14328 Sentence denotes The data analyses included four stages.
T133 14329-14523 Sentence denotes In the first stage, descriptive statistics were employed to calculate the means and standard deviations of the continuous variables and the percentage and frequency of the categorical variables.
T134 14524-14692 Sentence denotes In the second stage, in order to test the first hypothesis regarding the difference in subjective age before and during the COVID-19 pandemic, a paired t-test was used.
T135 14693-14961 Sentence denotes In the third stage, bivariate analyses were performed to examine the association between subjective age and the independent variable, mediator variables, and socioeconomic variables using an independent t-test, one-way ANOVA, and Pearson or Spearman correlation tests.
T136 14962-15157 Sentence denotes In the fourth stage, mediation analyses were then computed, and the selected mediators (depressive symptoms and malnutrition) were entered to test the components of the mediation model (Model 4).
T137 15158-15254 Sentence denotes The bootstrapping method was used to assess the indirect effects of the mediation model [62,63].
T138 15255-15634 Sentence denotes Thus, the mediation model was examined by directly testing the significance of the indirect effect of the independent variable (IV; feelings of loneliness) on the dependent variable (DV; subjective age) through the mediators (MeV; depressive symptoms and malnutrition), while controlling for background variables that had been identified in the bivariate analyses as significant.
T139 15635-15865 Sentence denotes This method is based on regression analysis and calculates the direct effect (weight C’, with a mediator), total effect (C, without mediator) and indirect effects (a × b weights) of an independent variable on a dependent variable.
T140 15866-15965 Sentence denotes The total and specific indirect effects were calculated through bootstrapping, set at 5000 samples.
T141 15966-16210 Sentence denotes Confidence intervals were calculated using this method by sorting the lowest to highest of these samples, yielding a 95-percentile confidence interval (if the number 0 falls within the confidence intervals, the tested effect is nonsignificant).
T142 16211-16291 Sentence denotes All analyses were run using SPSS 25.0 with the PROCESS statistical program [62].
T143 16292-16377 Sentence denotes All estimated effects reported by PROCESS are unstandardized regression coefficients.
T144 16379-16381 Sentence denotes 4.
T145 16382-16389 Sentence denotes Results
T146 16390-16536 Sentence denotes Table 1 presents the background variables, the descriptive statistics for the mediators and the independent and dependent variables of the sample.
T147 16537-16682 Sentence denotes The majority of the participants were women, aged between 65 and 95 (mean = 74.3, SD = 6.3) with moderate health status (Mean = 3.61, SD = 1.15).
T148 16683-16780 Sentence denotes Their education ranged from 6 to 21 years (Mean = 10.0, SD = 4.0) and most had a partner (71.1%).
T149 16781-16823 Sentence denotes About 50% were Arabs and the others, Jews.
T150 16824-16897 Sentence denotes No differences were found between the two ethnic groups (data not shown).
T151 16898-17179 Sentence denotes The feelings of loneliness of the participants were medium (Mean = 2.2, SD = 1.1); depressive symptoms were fairly low (Mean = 4.8, SD = 3.2); malnutrition was low-to-medium (Mean = 6.8, SD = 4.3) and subjective age during the COVID-19 pandemic was medium (Mean = 2.94, SD = 1.73).
T152 17180-17250 Sentence denotes The first hypothesis is supported by the results of the paired t-test.
T153 17251-17367 Sentence denotes A difference was indicated between the two times, and the participants felt older during the pandemic (see Table 2).
T154 17368-17710 Sentence denotes The results of the bivariate tests of the association between the research variables and subjective age during the COVID-19 pandemic reveal that the only demographic variable that correlated significantly with subjective age during the crisis was marital status (having a partner correlated positively with lower subjective age, see Table 3).
T155 17711-17832 Sentence denotes The results reveal that all the independent and mediation variables were significantly related to the dependent variable.
T156 17833-17960 Sentence denotes High levels of loneliness, depressive symptoms, and malnutrition correlated positively with subjective age during the pandemic.
T157 17962-17984 Sentence denotes The Mediation Analyses
T158 17985-18305 Sentence denotes Using the PROCESS model 4 [62,63], we tested the second and third hypotheses that during the crisis, feelings of loneliness would be associated directly with subjective age, and indirectly associated with subjective age through depressive symptoms and malnutrition, controlling for covariates (see Table 4 and Figure 1).
T159 18306-18491 Sentence denotes The results indicate a significant total direct effect (path c; without mediators) of loneliness on subjective age, and a significant indirect effect through malnutrition as a mediator.
T160 18492-18594 Sentence denotes No indirect connection was found between the second mediator (depressive symptoms) and subjective age.
T161 18595-18686 Sentence denotes No significant associations were found between the background variables and subjective age.
T162 18688-18690 Sentence denotes 5.
T163 18691-18701 Sentence denotes Discussion
T164 18702-18766 Sentence denotes The present research was conducted during the COVID-19 pandemic.
T165 18767-18988 Sentence denotes During this crisis, older adults are being considered a population at risk; therefore, people of this age are expected to maintain physical distance and reduce the frequency of leaving their home as much as possible [64].
T166 18989-19332 Sentence denotes In light of the loneliness potentially caused by social and physical distancing, the purpose of this study was to examine the possible connection between loneliness and subjective age during the COVID-19 pandemic, and to investigate whether loneliness was indirectly associated with subjective age through depressive symptoms and malnutrition.
T167 19333-19524 Sentence denotes Finally, an attempt was made to determine whether older adults, at a time when their age puts them at risk in terms of physical and mental health, felt older than their chronological age [1].
T168 19525-19680 Sentence denotes The research findings confirm the first hypothesis: the older adults’ subjective age was higher at this time of crisis compared with a less stressful time.
T169 19681-19841 Sentence denotes This result is consistent with those of other studies [1,65] that showed that older adults had a higher subjective age in times of crisis, distress, and stress.
T170 19842-19898 Sentence denotes There are several possible explanations of this finding.
T171 19899-19954 Sentence denotes First, the influence of stress and age are interactive.
T172 19955-20129 Sentence denotes Psychological stress can both imitate and worsen the effects of aging, with older adults usually showing greater immunological impairment and stress than younger adults [65].
T173 20130-20230 Sentence denotes Previous studies have shown that older subjective age is related to higher levels of stress [66,67].
T174 20231-20430 Sentence denotes This could be particularly true for daily stressors, which, if they accumulate, create persistent irritation and overload that may result in more serious stress reactions [68,69] such as less energy.
T175 20431-20518 Sentence denotes The resulting feeling (or actual state) of exhaustion is consistent with feeling older.
T176 20519-20739 Sentence denotes With regard to the second and third hypotheses, the results indicate a direct and positive connection between feelings of loneliness and subjective age; the lonelier the participants, the higher was their subjective age.
T177 20740-20800 Sentence denotes This finding is also consistent with the literature [19,29].
T178 20801-20967 Sentence denotes The size of one’s social network, the satisfaction related to it, and feeling part of the social network have been found to be associated with subjective age [29,70].
T179 20968-21071 Sentence denotes Researchers have also found that the connection between loneliness and subjective age is bidirectional.
T180 21072-21432 Sentence denotes Having a large social network is associated with younger subjective age; older adults who feel younger tend to be friendlier than their cohorts who feel older, and conversely, feeling older than one’s chronological age may limit the desire and capacity for maintaining social relationships, which may reflect compromised physical and emotional well-being [29].
T181 21433-21611 Sentence denotes The examination of two variables that might mediate the direct connection between loneliness and subjective age confirmed the effect of malnutrition, but not depressive symptoms.
T182 21612-21833 Sentence denotes Previous research has addressed the connection between loneliness and malnutrition, and has found that loneliness may affect appetite and nutrient intake through a decline in mood, physical functioning, or cognition [71].
T183 21834-22034 Sentence denotes These, in turn, combined with the difficulty of eating alone and changes in social status, particularly due to the loss of a spouse or friends of the same age group, can further inhibit appetite [72].
T184 22035-22099 Sentence denotes In comparison, eating with others can help prevent malnutrition.
T185 22100-22316 Sentence denotes It increases caloric intake, is related to healthier food habits [73,74], and maintains the motivation of older adults to eat and cook, providing them with opportunities for social interaction and connectedness [75].
T186 22317-22462 Sentence denotes Another possible explanation is the association between deconditioning and loneliness, deconditioning contributes to frailty and fear of falling.
T187 22463-22589 Sentence denotes The fear of falling could also contribute to avoiding grocery shopping and a diminished desire to stand while preparing meals.
T188 22590-22696 Sentence denotes To the best of our knowledge, the finding of a correlation between malnutrition and subjective age is new.
T189 22697-22871 Sentence denotes It can be explained by the findings of previous research that in older adults, a young subjective age is associated with good health, functional health, and wellbeing [4,45].
T190 22872-23123 Sentence denotes Moreover, a comparison between unobserved (blood pressure and telomere length) and observed (grip strength, expiratory flow, and waist circumference) health measures found that the observed health measures were connected to younger subjective age [2].
T191 23124-23294 Sentence denotes Against this background, it can be assumed that inadequate nutrition that leads to malnutrition could become an observed health problem that influences functional health.
T192 23295-23378 Sentence denotes These findings help explain the connection between malnutrition and subjective age.
T193 23380-23382 Sentence denotes 6.
T194 23383-23411 Sentence denotes Conclusions and Implications
T195 23412-23550 Sentence denotes The results of the present study indicate that there is an association between feelings of loneliness and malnutrition and subjective age.
T196 23551-23730 Sentence denotes The primary conclusion is that loneliness affects both malnutrition and subjective age (which, as noted, is associated with numerous negative psychological and physical outcomes).
T197 23731-24074 Sentence denotes To help older adults overcome these feelings, particularly during a pandemic and quarantine, it is important to develop new communication methods such as technologies for managing and addressing the needs of the older population, technologies for managing and providing remote medical services, and technologies to encourage social engagement.
T198 24075-24232 Sentence denotes Older adults who do not have access to advanced social network technologies can use more basic technologies like routine phone calls with family and friends.
T199 24233-24396 Sentence denotes MAH (Mental Health America) suggests 10 structured question in order to make a brief check on the physical, social, mental and nutritional status of older adults).
T200 24397-24554 Sentence denotes Moreover, volunteers and friends can visit under the Covid-19 safety regulations, or occasional visits to a park and being among other people can be helpful.
T201 24555-24680 Sentence denotes Similarly, the families of older adults should receive guidance on technology, so that they can meet while social distancing.
T202 24681-24798 Sentence denotes Another option is to encourage neighbors in the same building to talk to each other and find ways for mutual support.
T203 24799-24982 Sentence denotes Apart from loneliness, it is necessary to address the issue of subjective age, which has been found to rise during crises in general, and during the current quarantine, in particular.
T204 24983-25038 Sentence denotes Subjective age is associated with many health outcomes.
T205 25039-25232 Sentence denotes Therefore, when older adults are required to stay home as much as possible, it is imperative that policymakers take measures to relieve their loneliness and see that they have proper nutrition.
T206 25233-25496 Sentence denotes One possible means for achieving these two related outcomes is to provide psychological-nutrition intervention [76] by telephone (this kind of intervention includes a weekly telephone call for about half an hour, including general talks and nutrition guidelines).
T207 25497-25613 Sentence denotes This would provide human contact, as well as nutritional guidelines and encouragement to cook and eat healthy foods.
T208 25614-25669 Sentence denotes Three limitations of the current study should be noted.
T209 25670-25798 Sentence denotes One is the cross-sectional study design, which does not allow for the prediction of a causal relationship between the variables.
T210 25799-25937 Sentence denotes Future research should use longitudinal data to examine the relationship between feelings of loneliness, malnutrition, and subjective age.
T211 25938-26013 Sentence denotes A further limitation is the use of only one question concerning loneliness.
T212 26014-26095 Sentence denotes However, previous studies have also used a single question for this purpose [77].
T213 26096-26273 Sentence denotes Third, the ability to generalize the findings is limited, because the sample and the sampling procedure did not guarantee the representativeness of Jewish and Arab older adults.
T214 26274-26376 Sentence denotes The sample included only older adults who answered the telephone at the moment the researchers called.
T215 26377-26464 Sentence denotes Those who did not answer or did not have a telephone are not represented in this study.
T216 26465-26602 Sentence denotes Fourth, all variables were measured at the same time, therefore, general attitudes and emotions may have had an influence on all ratings.
T217 26603-26653 Sentence denotes These various factors may have biased the results.
T218 26654-26905 Sentence denotes Despite these limitations and the difficulty of making generalizations, the present study provides initial insights into the mechanisms of the association between loneliness, malnutrition, and subjective age during periods of imposed social isolation.
T219 26906-27078 Sentence denotes Future research could use a randomized sample that includes a personal income variable for each participant since personal income has a direct effect on nutritional intake.
T220 27079-27515 Sentence denotes Another possible topic of study could address malnutrition and feelings of loneliness due to reduced hearing/vision abilities in older adults, and the difficulty of shopping and cooking on the one hand and keeping social relationships on the other hand, especially in times of crisis such as the COVID-19 pandemic when communication is very difficult due to the masks, especially for older adults with reduced vision/ hearing abilities.
T221 27517-27640 Sentence denotes Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations.
T222 27642-27662 Sentence denotes Author Contributions
T223 27663-27721 Sentence denotes Supervision, S.T.; Writing—original draft, A.V.S. and I.Y.
T224 27722-27798 Sentence denotes All authors have read and agreed to the published version of the manuscript.
T225 27800-27807 Sentence denotes Funding
T226 27808-27934 Sentence denotes This research was funded by Tel Hai academic college grant number 3/2020-5 and the APC was funded by Tel Hai academic college.
T227 27936-27972 Sentence denotes Institutional Review Board Statement
T228 27973-28164 Sentence denotes The study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Ethics Committee of Tel Hai academic college (protocol code 3/2020-5; date of approval:
T229 28165-28176 Sentence denotes 14/4/2020).
T230 28178-28204 Sentence denotes Informed Consent Statement
T231 28205-28275 Sentence denotes Informed consent was obtained from all subjects involved in the study.
T232 28277-28298 Sentence denotes Conflicts of Interest
T233 28299-28432 Sentence denotes The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
T234 28434-28576 Sentence denotes Figure 1 Mediator model depicting direct and indirect effects of feelings loneliness on subjective age, controlling for background variables.
T235 28577-28646 Sentence denotes Graphic (A) depicts the total effect of loneliness on subjective age.
T236 28647-28789 Sentence denotes Graphic (B) depicts the direct effect of loneliness on subjective age, after including mediators and controlling for all background variables.
T237 28790-28846 Sentence denotes Values represent unstandardized regression coefficients.
T238 28847-28912 Sentence denotes Table 1 Descriptive statistics of the study variables (N = 201).
T239 28913-28969 Sentence denotes Background Characteristics N Valid % Mean SD Range
T240 28970-28976 Sentence denotes Gender
T241 28977-28991 Sentence denotes Male 96 47.8
T242 28992-29009 Sentence denotes Female 105 52.2
T243 29010-29042 Sentence denotes Health status 3.61 1.15 1–5
T244 29043-29059 Sentence denotes Age 74.3 6.3
T245 29060-29082 Sentence denotes Education 10.0 4.0
T246 29083-29097 Sentence denotes Marital status
T247 29098-29118 Sentence denotes No partner 54 26.9
T248 29119-29143 Sentence denotes Has a partner 143 71.1
T249 29144-29165 Sentence denotes Missing value 4 2.0
T250 29166-29186 Sentence denotes Independent variable
T251 29187-29223 Sentence denotes Loneliness feelings 2.2 1.1 1–4
T252 29224-29233 Sentence denotes Mediators
T253 29234-29272 Sentence denotes Depressive symptoms 4.77 3.2 0–15
T254 29273-29304 Sentence denotes Malnutrition 6.82 4.3 0–20
T255 29305-29323 Sentence denotes Dependent variable
T256 29324-29384 Sentence denotes Subjective age during COVID-19 1 pandemic 2.94 1.73 0–5
T257 29385-29407 Sentence denotes 1 Coronavirus disease.
T258 29408-29542 Sentence denotes Table 2 Paired t-tests between subjective age during the COVID-19 pandemic and subjective age before the COVID-19 pandemic (N = 201).
T259 29543-29574 Sentence denotes Variable Mean SD t p Value
T260 29575-29638 Sentence denotes Subjective age before COVID-19 pandemic 2.76 (1.7) 2.3 0.03
T261 29639-29691 Sentence denotes Subjective age during COVID-19 pandemic 2.94 (1.7)
T262 29692-29868 Sentence denotes Table 3 Results of bivariate tests between demographic characteristics, loneliness (the independent variable), mediators and subjective age during COVID-19 pandemic (N = 201).
T263 29869-29923 Sentence denotes Variables Subjective Age during the COVID-19 Pandemic
T264 29924-29949 Sentence denotes Mean SD Test a p Value
T265 29950-29977 Sentence denotes Demographic characteristics
T266 29978-30018 Sentence denotes Gender Male 2.75 1.8 t = −1.50 0.14
T267 30019-30036 Sentence denotes Female 3.11 1.7
T268 30037-30060 Sentence denotes Age r = −0.05 0.52
T269 30061-30090 Sentence denotes Education r = −0.08 0.29
T270 30091-30147 Sentence denotes Marital status With partner 2.77 1.7 t = −2.41 0.02
T271 30148-30175 Sentence denotes Without partner 3.43 1.68
T272 30176-30196 Sentence denotes Independent variable
T273 30197-30236 Sentence denotes Loneliness feelings r = 0.75 0.000
T274 30237-30246 Sentence denotes Mediators
T275 30247-30286 Sentence denotes Depressive symptoms r = 0.22 0.002
T276 30287-30319 Sentence denotes Malnutrition r = 0.27 0.000
T277 30320-30381 Sentence denotes at = independent t-test; r = Pearson correlation coefficient.
T278 30382-30463 Sentence denotes Table 4 Summary of the mediation model analyses using 5000 bootstraps (N = 201).
T279 30464-30623 Sentence denotes Covariates Independent Variable Mediating Variable Dependent Variable Covariates→DV IV→M MV→DV Direct EffectIV→DV Indirect Effect Total Effect Adj R2
T280 30624-30698 Sentence denotes (IV) (MeV) (DV) (path a) (path b) (path C’) (a × b) 95%CI (C) R2
T281 30699-30856 Sentence denotes Age group Loneliness feelings Depressive symptoms Subjective age during COVID-19 pandemic ns 0.16 ** 0.27 0.27 * 0.04 −0.003–0.14 0.35 ** 0.15 ***
T282 30857-30867 Sentence denotes Gender ns
T283 30868-30886 Sentence denotes Marital status ns
T284 30887-30947 Sentence denotes Education Malnutrition ns 0.50 * 0.08* 0.04 0.002–0.13
T285 30948-30954 Sentence denotes Notes:
T286 30955-31265 Sentence denotes Value labels of categorical variables: IV = Independent variable; M = mediator; Adj R2 = Adjusted R2; DV = Dependent variable; Age group (1 = 65–74, 2 = 75 and older); gender (1 = male, 2 = female); marital status (1 = has partner, 2 = no partner); ns = not significant. * p < 0.05. ** p < 0.01. *** p < 0.001.