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PMC:7796148 / 17808-22506 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
246 209-217 Disease denotes COVID-19 MESH:C000657245
247 218-225 Disease denotes anxiety MESH:D001007
248 388-396 Disease denotes COVID-19 MESH:C000657245
249 397-404 Disease denotes anxiety MESH:D001007
252 507-515 Disease denotes COVID-19 MESH:C000657245
253 537-544 Disease denotes anxiety MESH:D001007
258 949-957 Disease denotes COVID-19 MESH:C000657245
259 958-965 Disease denotes anxiety MESH:D001007
260 1236-1244 Disease denotes COVID-19 MESH:C000657245
261 1476-1487 Disease denotes PHQ-15 pain MESH:D010146
265 1559-1566 Disease denotes Anxiety MESH:D001007
266 1568-1578 Disease denotes Depression MESH:D000275
267 1584-1600 Disease denotes Traumatic Stress MESH:D000079225
279 1890-1902 Species denotes participants Tax:9606
280 1615-1622 Disease denotes anxiety MESH:D001007
281 1624-1634 Disease denotes depression MESH:D000275
282 1636-1652 Disease denotes traumatic stress MESH:D000079225
283 1657-1665 Disease denotes COVID-19 MESH:C000657245
284 1674-1681 Disease denotes anxiety MESH:D001007
285 1767-1783 Disease denotes traumatic stress MESH:D000079225
286 1788-1796 Disease denotes COVID-19 MESH:C000657245
287 1805-1812 Disease denotes anxiety MESH:D001007
288 1908-1915 Disease denotes anxiety MESH:D001007
289 1917-1927 Disease denotes depression MESH:D000275
297 2196-2201 Species denotes women Tax:9606
298 2237-2240 Species denotes men Tax:9606
299 2440-2445 Species denotes women Tax:9606
300 2468-2471 Species denotes men Tax:9606
301 2047-2054 Disease denotes anxiety MESH:D001007
302 2212-2219 Disease denotes anxiety MESH:D001007
303 2276-2286 Disease denotes Depression MESH:D000275
308 2706-2711 Species denotes women Tax:9606
309 2721-2724 Species denotes men Tax:9606
310 2518-2525 Disease denotes anxiety MESH:D001007
311 2533-2543 Disease denotes depression MESH:D000275
319 2986-2991 Species denotes women Tax:9606
320 3001-3004 Species denotes men Tax:9606
321 3212-3217 Species denotes women Tax:9606
322 3227-3230 Species denotes men Tax:9606
323 2817-2833 Disease denotes traumatic stress MESH:D000079225
324 3049-3057 Disease denotes COVID-19 MESH:C000657245
325 3066-3073 Disease denotes anxiety MESH:D001007
332 3280-3287 Disease denotes anxiety MESH:D001007
333 3295-3305 Disease denotes depression MESH:D000275
334 3307-3323 Disease denotes traumatic stress MESH:D000079225
335 3329-3337 Disease denotes COVID-19 MESH:C000657245
336 3346-3353 Disease denotes Anxiety MESH:D001007
337 3530-3546 Disease denotes traumatic stress MESH:D000079225
347 3785-3797 Species denotes participants Tax:9606
348 3863-3866 Species denotes men Tax:9606
349 3885-3890 Species denotes women Tax:9606
350 3618-3625 Disease denotes anxiety MESH:D001007
351 3626-3636 Disease denotes depression MESH:D000275
352 3685-3701 Disease denotes traumatic stress MESH:D000079225
353 3840-3848 Disease denotes COVID-19 MESH:C000657245
354 3849-3856 Disease denotes anxiety MESH:D001007
355 3872-3879 Disease denotes anxious MESH:D001007
362 4066-4073 Disease denotes anxiety MESH:D001007
363 4074-4084 Disease denotes depression MESH:D000275
364 4132-4148 Disease denotes traumatic stress MESH:D000079225
365 4258-4265 Disease denotes anxiety MESH:D001007
366 4266-4276 Disease denotes depression MESH:D000275
367 4336-4352 Disease denotes traumatic stress MESH:D000079225
374 4454-4462 Disease denotes COVID-19 MESH:C000657245
375 4508-4518 Disease denotes depression MESH:D000275
376 4519-4526 Disease denotes anxiety MESH:D001007
377 4558-4574 Disease denotes traumatic stress MESH:D000079225
378 4610-4618 Disease denotes COVID-19 MESH:C000657245
379 4619-4626 Disease denotes anxiety MESH:D001007

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T41 218-225 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T42 397-404 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T43 537-544 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T44 958-965 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T45 1483-1487 Phenotype denotes pain http://purl.obolibrary.org/obo/HP_0012531
T46 1559-1566 Phenotype denotes Anxiety http://purl.obolibrary.org/obo/HP_0000739
T47 1568-1578 Phenotype denotes Depression http://purl.obolibrary.org/obo/HP_0000716
T48 1615-1622 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T49 1624-1634 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T50 1674-1681 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T51 1805-1812 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T52 1908-1915 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T53 1917-1927 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T54 2047-2054 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T55 2212-2219 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T56 2276-2286 Phenotype denotes Depression http://purl.obolibrary.org/obo/HP_0000716
T57 2518-2525 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T58 2533-2543 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T59 3066-3073 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T60 3280-3287 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T61 3295-3305 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T62 3346-3353 Phenotype denotes Anxiety http://purl.obolibrary.org/obo/HP_0000739
T63 3618-3625 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T64 3626-3636 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T65 3849-3856 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T66 4066-4073 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T67 4074-4084 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T68 4258-4265 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T69 4266-4276 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T70 4508-4518 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T71 4519-4526 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T72 4619-4626 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T151 0-2 Sentence denotes 3.
T152 3-10 Sentence denotes Results
T153 12-16 Sentence denotes 3.1.
T154 17-33 Sentence denotes Somatic Symptoms
T155 34-117 Sentence denotes Correlations for all the variables included in Models 1 and 2 are shown in Table 1.
T156 118-261 Sentence denotes The PHQ-15 subscales and the total score were positively and significantly correlated with COVID-19 anxiety, as well as with GAD-7 total score.
T157 262-347 Sentence denotes These correlations are in line with results from the first wave of the UK study [20].
T158 348-426 Sentence denotes Figure 1 shows the relationship between COVID-19 anxiety and somatic symptoms.
T159 427-482 Sentence denotes Table 2 shows the estimates from the regression models.
T160 483-678 Sentence denotes In Model 1, considering COVID-19 first quintile as no-anxiety, we can observe significant differences between the baseline and the other quantiles both in PHQ-15 subscales and in its total score.
T161 679-875 Sentence denotes In the sample, the aggravation of the somatic symptoms between quintiles seems to be characterized by a more linear increase than in the UK data, with a similar wider effect over the 5th quintile.
T162 876-934 Sentence denotes In Model 2, the control variables were taken into account.
T163 935-1066 Sentence denotes The effect of COVID-19 anxiety on somatic symptoms was weaker but similar to Model 1, especially referred to the total scale score.
T164 1067-1222 Sentence denotes The presence of pre-existing health problems and high scores on GAD-7 significantly worsen specific and general somatic symptoms, confirming UK’s findings.
T165 1223-1306 Sentence denotes Mourning for COVID-19 losses also has a detrimental effect on psychological health.
T166 1307-1347 Sentence denotes No effect of household income was found.
T167 1348-1442 Sentence denotes In terms of regions, Campania showed higher scores of somatic symptoms than the other regions.
T168 1443-1552 Sentence denotes Campania scores were high in the PHQ-15 pain subscale and in the gastrointestinal subscale, but also overall.
T169 1554-1558 Sentence denotes 3.2.
T170 1559-1600 Sentence denotes Anxiety, Depression, and Traumatic Stress
T171 1601-1715 Sentence denotes We focused on anxiety, depression, traumatic stress and COVID-19 related anxiety, following Shevlin et al. (2020).
T172 1716-1937 Sentence denotes In order to be consistent with the original study, traumatic stress and COVID-19 related anxiety where treated independently, whereas a new variable was computed to describe participants with anxiety, depression, or both.
T173 1938-2034 Sentence denotes Sample size, percentages and adjusted odds ratio are summarized in Table 3, Table 4 and Table 5.
T174 2035-2104 Sentence denotes The rate of anxiety (GAD-7) in the overall sample was 21.59% (95% CI:
T175 2105-2241 Sentence denotes 15.93%–20.72%), with no differences between regions (χ2(3) = 4.07, p = 0.25) and with more women above the anxiety cut-off (11.75%, men:
T176 2242-2275 Sentence denotes 6.45%; χ2(1) = 15.94, p < 0.001).
T177 2276-2325 Sentence denotes Depression (PHQ-9), with a rate of 21.4% (95% CI:
T178 2326-2505 Sentence denotes 18.95%–24.03%), showed no differences between regions (χ2(3) = 0.29, p = 0.96) but was significantly higher among women (12.52%), compared to men (8.86%; χ2(1) = 5.82, p = 0.016).
T179 2506-2562 Sentence denotes The rate of anxiety and/or depression was 26.11 (95% CI:
T180 2563-2578 Sentence denotes 23.48%–28.91%).
T181 2579-2712 Sentence denotes No significant differences between regions were detected (χ2(3) = 1.78 p = 0.61), whereas the gender difference was confirmed (women:
T182 2713-2725 Sentence denotes 15.90%, men:
T183 2726-2760 Sentence denotes 10.21%; χ2(1) = 13.37, p < 0.001).
T184 2761-2856 Sentence denotes Using the ITQ scale, 25.92% of the sample was above the traumatic stress cut-off score (95% CI:
T185 2857-2872 Sentence denotes 23.34%–28.77%).
T186 2873-2992 Sentence denotes No difference was found between regions (χ2(3) = 4.30, p = 0.23), while the gender effect was again significant (women:
T187 2993-3005 Sentence denotes 15.11%, men:
T188 3006-3039 Sentence denotes 10.88%; χ2(1) = 7.16, p = 0.007).
T189 3040-3101 Sentence denotes Finally, COVID-19 related anxiety was 18.30% overall (95% CI:
T190 3102-3117 Sentence denotes 16.02%–20.82%).
T191 3118-3218 Sentence denotes Regions showed a similar rate (χ2(3) = 2.66, p = 0.44) whereas a gender difference was found (women:
T192 3219-3231 Sentence denotes 12.14%, men:
T193 3232-3265 Sentence denotes 6.17%; χ2(1) = 20–65, p < 0.001).
T194 3266-3470 Sentence denotes We considered anxiety and/or depression, traumatic stress, and COVID-19-related Anxiety as dependent variables in three separate multiple logistic regressions (respectively, Table 3, Table 4 and Table 5).
T195 3471-3547 Sentence denotes Figure 2 shows the plot of the odds ratio for the model of traumatic stress.
T196 3548-3798 Sentence denotes The age effect, observed by Shevlin and colleagues, was confirmed for anxiety/depression (Adj OR = 0.96, CI = 0.95–0.97, p < 0.001), and traumatic stress (Adj OR = 0.97, CI = 0.96–0.98, p < 0.001), showing more moderate cases in younger participants.
T197 3799-3955 Sentence denotes A gender difference was observed only in COVID-19 anxiety, with men less anxious than women about the new virus (Adj OR = 0.33, CI = −0.03–0.69, p < 0.001).
T198 3956-4001 Sentence denotes No differences were observed between regions.
T199 4002-4396 Sentence denotes The presence of minors in the house had a detrimental effect on anxiety/depression (Adj OR = 1.55, CI = 1.20–1.90, p = 0.002) and traumatic stress (Adj OR = 1.52, CI = 1.17–1.87, p = 0.004), as did the presence of pre-existing health conditions in others (anxiety/depression; Adj OR = 1.53, CI = 1.14–1.91, p = 0.006) and themselves (traumatic stress; Adj OR = 1.59, CI = 1.15–2.02; p = 0.008).
T200 4397-4698 Sentence denotes Interestingly, an increase in perceived risk to contract COVID-19 in the following four weeks had an effect on depression/anxiety (LR χ2(3) = 54.24, p < 0.001), traumatic stress (LR χ2(3) = 66.14, p < 0.001), and COVID-19 anxiety (LR χ2(3) = 84.74, p < 0.001), mostly in the third and fourth quartile.