PMC:7796052 / 957-1773 JSON TXT

Annnotations TAB JSON ListView MergeView

Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
45	450-463	Gene	denotes	interleukin-6	Gene:3569
46	465-469	Gene	denotes	IL-6	Gene:3569
47	13-21	Species	denotes	patients	Tax:9606
48	36-46	Species	denotes	SARS-Cov-2	Tax:2697049
49	306-314	Species	denotes	patients	Tax:9606
50	499-507	Species	denotes	patients	Tax:9606
51	767-778	Species	denotes	Ebola virus	Tax:205488
52	554-567	Chemical	denotes	dexamethasone	MESH:D003907
53	677-687	Chemical	denotes	remdesivir	MESH:C000606551
54	22-30	Disease	denotes	infected	MESH:D007239
55	92-101	Disease	denotes	pneumonia	MESH:D011014
56	129-138	Disease	denotes	hypoxemia	MESH:D000860
57	140-175	Disease	denotes	acute respiratory distress syndrome	MESH:D012128
58	177-181	Disease	denotes	ARDS	MESH:D012128
59	184-199	Disease	denotes	pulmonary edema	MESH:D011654
60	201-206	Disease	denotes	shock	MESH:D012769
61	208-226	Disease	denotes	metabolic acidosis	MESH:D000138
62	228-251	Disease	denotes	coagulation dysfunction	MESH:D001778
63	256-289	Disease	denotes	multiple organ functional failure	MESH:D009102
64	297-305	Disease	denotes	Covid-19	MESH:C000657245
65	641-651	Disease	denotes	infections	MESH:D007239

Id	Subject	Object	Predicate	Lexical cue	hp_id
T2	92-101	Phenotype	denotes	pneumonia	http://purl.obolibrary.org/obo/HP_0002090
T3	129-138	Phenotype	denotes	hypoxemia	http://purl.obolibrary.org/obo/HP_0012418
T4	146-166	Phenotype	denotes	respiratory distress	http://purl.obolibrary.org/obo/HP_0002098
T5	184-199	Phenotype	denotes	pulmonary edema	http://purl.obolibrary.org/obo/HP_0100598
T6	201-206	Phenotype	denotes	shock	http://purl.obolibrary.org/obo/HP_0031273
T7	208-226	Phenotype	denotes	metabolic acidosis	http://purl.obolibrary.org/obo/HP_0001942
T8	732-741	Phenotype	denotes	hepatitis	http://purl.obolibrary.org/obo/HP_0012115

Id	Subject	Object	Predicate	Lexical cue
T10	0-296	Sentence	denotes	About 20% of patients infected with SARS-Cov-2 develop respiratory complications, including pneumonia, that may evolve to severe hypoxemia, acute respiratory distress syndrome (ARDS), pulmonary edema, shock, metabolic acidosis, coagulation dysfunction and multiple organ functional failure [1,2].
T11	297-481	Sentence	denotes	Covid-19 patients with severe symptoms exhibit an immune response characterized by elevated serum levels of diverse proinflammatory molecules, including interleukin-6 (IL-6) [3,4,5,6].
T12	482-816	Sentence	denotes	Presently, these patients are treated with anti-inflammatory drugs like dexamethasone [7] or cytokine inhibitors, combined with antibiotics to treat secondary infections, sometimes combined with remdesivir, an antiviral originally developed to treat hepatitis C and tested against the Ebola virus disease to reduce the viral load [8].