PMC:7796041 / 41854-43306 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"1169","span":{"begin":658,"end":671},"obj":"Gene"},{"id":"1170","span":{"begin":587,"end":590},"obj":"Gene"},{"id":"1171","span":{"begin":0,"end":19},"obj":"Disease"},{"id":"1172","span":{"begin":33,"end":52},"obj":"Disease"},{"id":"1173","span":{"begin":166,"end":178},"obj":"Disease"},{"id":"1174","span":{"begin":209,"end":231},"obj":"Disease"},{"id":"1175","span":{"begin":333,"end":341},"obj":"Disease"},{"id":"1176","span":{"begin":1367,"end":1388},"obj":"Disease"},{"id":"1177","span":{"begin":1417,"end":1422},"obj":"Disease"}],"attributes":[{"id":"A1169","pred":"tao:has_database_id","subj":"1169","obj":"Gene:3569"},{"id":"A1170","pred":"tao:has_database_id","subj":"1170","obj":"Gene:1401"},{"id":"A1171","pred":"tao:has_database_id","subj":"1171","obj":"MESH:D001281"},{"id":"A1172","pred":"tao:has_database_id","subj":"1172","obj":"MESH:D001281"},{"id":"A1173","pred":"tao:has_database_id","subj":"1173","obj":"MESH:D006973"},{"id":"A1174","pred":"tao:has_database_id","subj":"1174","obj":"MESH:D002318"},{"id":"A1175","pred":"tao:has_database_id","subj":"1175","obj":"MESH:D003920"},{"id":"A1176","pred":"tao:has_database_id","subj":"1176","obj":"MESH:D009203"},{"id":"A1177","pred":"tao:has_database_id","subj":"1177","obj":"MESH:D003643"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Atrial Fibrillation (n = 11) No Atrial Fibrillation (n = 128) p-Value\nFemale 2 (18.2) 45 (35.2) 0.287 *\nAge (years), mean ± SD 71.6 ± 8.9 60.2 ± 16.4 0.024 †\nHypertension 6 (54.5) 54 (42.2) 0.491 *\nCardiovascular disease 4 (36.4) 13 (10.2) 0.023 *\nLVEF (%), mean ± SD 56.8 ± 10.1 (n = 5) 57.0 ± 6.9 (n = 24) 0.966 †\nDiabetes 3 (27.3) 23 (18.0) 0.358 *\nObesity 2 (22.2) (n = 9) 29 (26.9) (n = 104) 1.000 *\nhsTnT (pg/mL) 132 (37.0; 993) (n = 7) 12.0 (7.0; 30.0) (n = 111) \u003c0.001 ‡\nNTproBNP (ng/L) 7,304 (4,336; 32,627) (n = 7) 535 (187; 2358) (n = 99) 0.001 ‡\nCRP (mg/L) 214 (150; 288) (n = 9) 103 (48.0; 164) (n = 126) 0.012 ‡\nInterleukin-6 (ng/L) 2,132 (358; 4538) (n = 4) 50.0 (25.0; 113) (n = 91) 0.004 ‡\nLDH (U/L) 719 (493; 836) (n = 9) 415 (319; 530) (n = 123) 0.003 ‡\nDuration of hospitalization (days), median (P25; P75) 31.0 (16.0; 35.5) (n = 8) 9.0 (5.0; 15.0) (n = 120) 0.007 ‡\nAdmission to ICU/IMC 8 (72.7) 46 (35.9) 0.016 *\nDuration of ICU/IMC stay (days), median (P25; P75) 28.5 (14.5; 33.0) 7.5 (3.0; 18.5) 0.019 ‡\nOxygen therapy 7 (63.6) 79 (61.7) 1.000 *\nHFNC/NIV therapy 6 (54.5) 23 (18.1) 0.008 *\nMechanical ventilation 9 (81.8) 20 (15.6) \u003c0.001 *\nDuration of ventilation (days), median (P25; P75) 18.0 (9.5; 33.0) 16.5 (7.3; 26.5) 0.562 ‡\nVasopressor therapy 7 (63.6) 15 (11.7) \u003c0.001 *\nMyocardial infarction 2 (18.2) 2 (1.6) 0.026 *\nDeath 4 (36.4) 14 (10.9) 0.029 *"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T256","span":{"begin":0,"end":19},"obj":"Phenotype"},{"id":"T257","span":{"begin":33,"end":52},"obj":"Phenotype"},{"id":"T258","span":{"begin":166,"end":178},"obj":"Phenotype"},{"id":"T259","span":{"begin":209,"end":231},"obj":"Phenotype"},{"id":"T260","span":{"begin":372,"end":379},"obj":"Phenotype"},{"id":"T261","span":{"begin":1367,"end":1388},"obj":"Phenotype"}],"attributes":[{"id":"A256","pred":"hp_id","subj":"T256","obj":"http://purl.obolibrary.org/obo/HP_0005110"},{"id":"A257","pred":"hp_id","subj":"T257","obj":"http://purl.obolibrary.org/obo/HP_0005110"},{"id":"A258","pred":"hp_id","subj":"T258","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A259","pred":"hp_id","subj":"T259","obj":"http://purl.obolibrary.org/obo/HP_0001626"},{"id":"A260","pred":"hp_id","subj":"T260","obj":"http://purl.obolibrary.org/obo/HP_0001513"},{"id":"A261","pred":"hp_id","subj":"T261","obj":"http://purl.obolibrary.org/obo/HP_0001658"}],"text":"Atrial Fibrillation (n = 11) No Atrial Fibrillation (n = 128) p-Value\nFemale 2 (18.2) 45 (35.2) 0.287 *\nAge (years), mean ± SD 71.6 ± 8.9 60.2 ± 16.4 0.024 †\nHypertension 6 (54.5) 54 (42.2) 0.491 *\nCardiovascular disease 4 (36.4) 13 (10.2) 0.023 *\nLVEF (%), mean ± SD 56.8 ± 10.1 (n = 5) 57.0 ± 6.9 (n = 24) 0.966 †\nDiabetes 3 (27.3) 23 (18.0) 0.358 *\nObesity 2 (22.2) (n = 9) 29 (26.9) (n = 104) 1.000 *\nhsTnT (pg/mL) 132 (37.0; 993) (n = 7) 12.0 (7.0; 30.0) (n = 111) \u003c0.001 ‡\nNTproBNP (ng/L) 7,304 (4,336; 32,627) (n = 7) 535 (187; 2358) (n = 99) 0.001 ‡\nCRP (mg/L) 214 (150; 288) (n = 9) 103 (48.0; 164) (n = 126) 0.012 ‡\nInterleukin-6 (ng/L) 2,132 (358; 4538) (n = 4) 50.0 (25.0; 113) (n = 91) 0.004 ‡\nLDH (U/L) 719 (493; 836) (n = 9) 415 (319; 530) (n = 123) 0.003 ‡\nDuration of hospitalization (days), median (P25; P75) 31.0 (16.0; 35.5) (n = 8) 9.0 (5.0; 15.0) (n = 120) 0.007 ‡\nAdmission to ICU/IMC 8 (72.7) 46 (35.9) 0.016 *\nDuration of ICU/IMC stay (days), median (P25; P75) 28.5 (14.5; 33.0) 7.5 (3.0; 18.5) 0.019 ‡\nOxygen therapy 7 (63.6) 79 (61.7) 1.000 *\nHFNC/NIV therapy 6 (54.5) 23 (18.1) 0.008 *\nMechanical ventilation 9 (81.8) 20 (15.6) \u003c0.001 *\nDuration of ventilation (days), median (P25; P75) 18.0 (9.5; 33.0) 16.5 (7.3; 26.5) 0.562 ‡\nVasopressor therapy 7 (63.6) 15 (11.7) \u003c0.001 *\nMyocardial infarction 2 (18.2) 2 (1.6) 0.026 *\nDeath 4 (36.4) 14 (10.9) 0.029 *"}

{"project":"LitCovid-sentences","denotations":[{"id":"T365","span":{"begin":0,"end":71},"obj":"Sentence"},{"id":"T366","span":{"begin":72,"end":108},"obj":"Sentence"},{"id":"T367","span":{"begin":109,"end":165},"obj":"Sentence"},{"id":"T368","span":{"begin":166,"end":208},"obj":"Sentence"},{"id":"T369","span":{"begin":209,"end":261},"obj":"Sentence"},{"id":"T370","span":{"begin":262,"end":332},"obj":"Sentence"},{"id":"T371","span":{"begin":333,"end":371},"obj":"Sentence"},{"id":"T372","span":{"begin":372,"end":427},"obj":"Sentence"},{"id":"T373","span":{"begin":428,"end":504},"obj":"Sentence"},{"id":"T374","span":{"begin":505,"end":586},"obj":"Sentence"},{"id":"T375","span":{"begin":587,"end":657},"obj":"Sentence"},{"id":"T376","span":{"begin":658,"end":741},"obj":"Sentence"},{"id":"T377","span":{"begin":742,"end":810},"obj":"Sentence"},{"id":"T378","span":{"begin":811,"end":927},"obj":"Sentence"},{"id":"T379","span":{"begin":928,"end":978},"obj":"Sentence"},{"id":"T380","span":{"begin":979,"end":1074},"obj":"Sentence"},{"id":"T381","span":{"begin":1075,"end":1119},"obj":"Sentence"},{"id":"T382","span":{"begin":1120,"end":1166},"obj":"Sentence"},{"id":"T383","span":{"begin":1167,"end":1220},"obj":"Sentence"},{"id":"T384","span":{"begin":1221,"end":1315},"obj":"Sentence"},{"id":"T385","span":{"begin":1316,"end":1366},"obj":"Sentence"},{"id":"T386","span":{"begin":1367,"end":1416},"obj":"Sentence"},{"id":"T387","span":{"begin":1417,"end":1452},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Atrial Fibrillation (n = 11) No Atrial Fibrillation (n = 128) p-Value\nFemale 2 (18.2) 45 (35.2) 0.287 *\nAge (years), mean ± SD 71.6 ± 8.9 60.2 ± 16.4 0.024 †\nHypertension 6 (54.5) 54 (42.2) 0.491 *\nCardiovascular disease 4 (36.4) 13 (10.2) 0.023 *\nLVEF (%), mean ± SD 56.8 ± 10.1 (n = 5) 57.0 ± 6.9 (n = 24) 0.966 †\nDiabetes 3 (27.3) 23 (18.0) 0.358 *\nObesity 2 (22.2) (n = 9) 29 (26.9) (n = 104) 1.000 *\nhsTnT (pg/mL) 132 (37.0; 993) (n = 7) 12.0 (7.0; 30.0) (n = 111) \u003c0.001 ‡\nNTproBNP (ng/L) 7,304 (4,336; 32,627) (n = 7) 535 (187; 2358) (n = 99) 0.001 ‡\nCRP (mg/L) 214 (150; 288) (n = 9) 103 (48.0; 164) (n = 126) 0.012 ‡\nInterleukin-6 (ng/L) 2,132 (358; 4538) (n = 4) 50.0 (25.0; 113) (n = 91) 0.004 ‡\nLDH (U/L) 719 (493; 836) (n = 9) 415 (319; 530) (n = 123) 0.003 ‡\nDuration of hospitalization (days), median (P25; P75) 31.0 (16.0; 35.5) (n = 8) 9.0 (5.0; 15.0) (n = 120) 0.007 ‡\nAdmission to ICU/IMC 8 (72.7) 46 (35.9) 0.016 *\nDuration of ICU/IMC stay (days), median (P25; P75) 28.5 (14.5; 33.0) 7.5 (3.0; 18.5) 0.019 ‡\nOxygen therapy 7 (63.6) 79 (61.7) 1.000 *\nHFNC/NIV therapy 6 (54.5) 23 (18.1) 0.008 *\nMechanical ventilation 9 (81.8) 20 (15.6) \u003c0.001 *\nDuration of ventilation (days), median (P25; P75) 18.0 (9.5; 33.0) 16.5 (7.3; 26.5) 0.562 ‡\nVasopressor therapy 7 (63.6) 15 (11.7) \u003c0.001 *\nMyocardial infarction 2 (18.2) 2 (1.6) 0.026 *\nDeath 4 (36.4) 14 (10.9) 0.029 *"}