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PMC:7795966 / 30054-31054 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1061 13-18 Gene denotes MetHb Gene:3048
1062 949-954 Gene denotes MetHb Gene:3048
1063 617-622 Gene denotes MetHb Gene:3048
1064 521-526 Gene denotes MetHb Gene:3048
1065 452-457 Gene denotes MetHb Gene:3048
1066 389-394 Gene denotes MetHb Gene:3048
1067 216-221 Gene denotes MetHb Gene:3048
1068 60-68 Species denotes patients Tax:9606
1069 642-650 Species denotes patients Tax:9606
1070 128-134 Chemical denotes oxygen MESH:D010100
1071 323-327 Chemical denotes SaO2
1072 365-369 Chemical denotes SaO2
1073 432-436 Chemical denotes SaO2
1074 712-716 Chemical denotes SaO2
1075 962-965 Chemical denotes tHb
1076 51-59 Disease denotes COVID-19 MESH:C000657245
1077 633-641 Disease denotes COVID-19 MESH:C000657245

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T221 0-199 Sentence denotes Knowledge of MetHb and COHb levels in the blood of COVID-19 patients is also relevant to prevent misinterpretations of arterial oxygen saturation values measured with fingertip pulse oximetry (SpO2).
T222 200-270 Sentence denotes This is because MetHb and COHb interfere with the measurement of SpO2.
T223 271-339 Sentence denotes An overestimation of the true arterial oxygenation (SaO2) can occur.
T224 340-496 Sentence denotes In case of a decrease in SaO2 and an increase in MetHb or COHb, SpO2 will diverge more from SaO2 the higher the MetHb and COHb concentration (see Figure 4).
T225 497-799 Sentence denotes For example, assuming a MetHb concentration of around 25% (corresponding to the upper end of the confidence interval of MetHb values in COVID-19 patients reported by Alamdari et al. [21]) and an assumed decrease of SaO2 to 75%, the SpO2 measurements would indicate a falsely too high SpO2 of about 88%.
T226 800-1000 Sentence denotes Measurement with pulse CO-oximetry instead of pulse oximetry would circumvent this problem since pulse CO-oximetry is able to non-invasively measure MetHb, COHb, tHb, and the correct SpO2. [83,84,85].