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PMC:7795966 / 11348-12995 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
435 536-541 Gene denotes MetHb Gene:3048
436 1527-1532 Gene denotes MetHb Gene:3048
437 962-967 Gene denotes MetHb Gene:3048
438 1479-1484 Gene denotes MetHb Gene:3048
439 1131-1136 Gene denotes MetHb Gene:3048
440 1062-1067 Gene denotes MetHb Gene:3048
441 402-407 Gene denotes MetHb Gene:3048
442 68-73 Gene denotes MetHb Gene:3048
443 54-62 Species denotes patients Tax:9606
444 121-131 Species denotes SARS-CoV-2 Tax:2697049
445 662-672 Species denotes SARS-CoV-2 Tax:2697049
446 1243-1253 Species denotes SARS-CoV-2 Tax:2697049
447 1592-1599 Species denotes patient Tax:9606
448 246-264 Chemical denotes hydroxychloroquine MESH:D006886
449 266-278 Chemical denotes azithromycin MESH:D017963
450 283-294 Chemical denotes ceftriaxone MESH:D002443
451 492-506 Chemical denotes methylene blue MESH:D008751
452 511-524 Chemical denotes ascorbic acid MESH:D001205
453 804-822 Chemical denotes hydroxychloroquine MESH:D006886
454 824-836 Chemical denotes azithromycin MESH:D017963
455 838-846 Chemical denotes cefepime MESH:D000077723
456 848-858 Chemical denotes vancomycin MESH:D014640
457 864-872 Chemical denotes apixaban MESH:C522181
458 1020-1034 Chemical denotes methylene blue MESH:D008751
459 1039-1052 Chemical denotes ascorbic acid MESH:D001205
460 1369-1381 Chemical denotes azithromycin MESH:D017963
461 1386-1404 Chemical denotes hydroxychloroquine MESH:D006886
462 1511-1525 Chemical denotes methylene blue MESH:D008751
463 45-53 Disease denotes COVID-19 MESH:C000657245
464 185-218 Disease denotes acute hypoxic respiratory failure MESH:D012120
465 598-613 Disease denotes G6PC deficiency MESH:D007153
466 691-696 Disease denotes obese MESH:D009765
467 706-723 Disease denotes diabetes mellitus MESH:D003920
468 763-790 Disease denotes hypoxic respiratory failure MESH:D012131
469 1179-1194 Disease denotes G6PD deficiency MESH:D005955
470 1272-1289 Disease denotes diabetes mellitus MESH:D003920
471 1328-1355 Disease denotes hypoxic respiratory failure MESH:D012131
472 1465-1472 Disease denotes hypoxia MESH:D000860
473 1631-1646 Disease denotes G6PD deficiency MESH:D005955

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T28 199-218 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T29 706-723 Phenotype denotes diabetes mellitus http://purl.obolibrary.org/obo/HP_0000819
T30 771-790 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T31 1272-1289 Phenotype denotes diabetes mellitus http://purl.obolibrary.org/obo/HP_0000819
T32 1336-1355 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T33 1465-1472 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T94 0-87 Sentence denotes Naymagon et al. [18] reported three cases of COVID-19 patients with MetHb measurements.
T95 88-233 Sentence denotes The first case was a 50-year-old SARS-CoV-2 positive man with no medical history presenting with acute hypoxic respiratory failure in the clinic.
T96 234-323 Sentence denotes He received hydroxychloroquine, azithromycin and ceftriaxone, and mechanical ventilation.
T97 324-401 Sentence denotes He showed persistently low SpO2 values despite being mechanically ventilated.
T98 402-475 Sentence denotes MetHb values increased steadily, peaking at 10.6% on day six (Figure 2a).
T99 476-575 Sentence denotes Treatments with methylene blue and ascorbic acid normalized MetHb and his clinical status improved.
T100 576-627 Sentence denotes A genetic analysis of G6PC deficiency was not done.
T101 628-791 Sentence denotes The second case was a 52-year-old SARS-CoV-2 positive morbidly obese man with diabetes mellitus, admitted to the hospital due to acute hypoxic respiratory failure.
T102 792-906 Sentence denotes He received hydroxychloroquine, azithromycin, cefepime, vancomycin, and apixaban, and was mechanically ventilated.
T103 907-1007 Sentence denotes A persistently low SpO2 was recognized and testing for MetHb resulted in a value of 22% (Figure 2a).
T104 1008-1086 Sentence denotes He received methylene blue and ascorbic acid, but his MetHb increased to >30%.
T105 1087-1155 Sentence denotes After receiving red blood cell transfusion, MetHb decreased to 2.9%.
T106 1156-1209 Sentence denotes No genetic analysis of G6PD deficiency was performed.
T107 1210-1356 Sentence denotes The third case was a 54-year-old SARS-CoV-2 positive man with diabetes mellitus admitted to the hospital due to acute hypoxic respiratory failure.
T108 1357-1437 Sentence denotes He received azithromycin and hydroxychloroquine and was mechanically ventilated.
T109 1438-1494 Sentence denotes He demonstrated persistent hypoxia and a MetHb of 13.7%.
T110 1495-1572 Sentence denotes After receiving methylene blue, MetHb did not improve and increased to 18.8%.
T111 1573-1605 Sentence denotes Shortly after, the patient died.
T112 1606-1647 Sentence denotes Genetic testing revealed G6PD deficiency.