PMC:7795856 / 6071-6464 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"165","span":{"begin":152,"end":163},"obj":"Gene"},{"id":"166","span":{"begin":376,"end":379},"obj":"Gene"}],"attributes":[{"id":"A165","pred":"tao:has_database_id","subj":"165","obj":"Gene:7295"},{"id":"A166","pred":"tao:has_database_id","subj":"166","obj":"Gene:134864"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"n such as natural ProTα [26], as artificial concatamers [27], in fusion with an intein [28] or in fusion with a highly expressed bacterial protein like thioredoxin [29]. In each case, enzymatic or chemical cleavage is necessary to liberate the mature peptide, which complicates the biopharmaceutical downstream process. Second, after administration in vivo, the small peptide Tα1 is quickly el"}

{"project":"LitCovid-sentences","denotations":[{"id":"T40","span":{"begin":170,"end":319},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"n such as natural ProTα [26], as artificial concatamers [27], in fusion with an intein [28] or in fusion with a highly expressed bacterial protein like thioredoxin [29]. In each case, enzymatic or chemical cleavage is necessary to liberate the mature peptide, which complicates the biopharmaceutical downstream process. Second, after administration in vivo, the small peptide Tα1 is quickly el"}