PMC:7795856 / 358-698
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
19 | 290-293 | Gene | denotes | Tα1 | Gene:134864 |
21 | 297-313 | Species | denotes | Escherichia coli | Tax:562 |
25 | 232-233 | Chemical | denotes | N | MESH:D009584 |
26 | 249-253 | Chemical | denotes | RimJ |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5 | 1-164 | Sentence | denotes | Manufacturing of this N-terminally acetylated 28-residue peptide is demanding, and its short plasma half-life limits in vivo efficacy and requires frequent dosing. |
T6 | 165-328 | Sentence | denotes | Here, we combined the PASylation technology with enzymatic in situ N-acetylation by RimJ to produce a long-acting version of Tα1 in Escherichia coli at high yield. |