PMC:7795856 / 234-688 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
19	414-417	Gene	denotes	Tα1	Gene:134864
21	421-437	Species	denotes	Escherichia coli	Tax:562
25	356-357	Chemical	denotes	N	MESH:D009584
26	373-377	Chemical	denotes	RimJ
32	93-101	Disease	denotes	COVID-19	MESH:C000657245
33	102-112	Disease	denotes	infections	MESH:D007239
34	117-123	Disease	denotes	cancer	MESH:D009369

Id	Subject	Object	Predicate	Lexical cue	hp_id
T4	117-123	Phenotype	denotes	cancer	http://purl.obolibrary.org/obo/HP_0002664

Id	Subject	Object	Predicate	Lexical cue
T5	125-288	Sentence	denotes	Manufacturing of this N-terminally acetylated 28-residue peptide is demanding, and its short plasma half-life limits in vivo efficacy and requires frequent dosing.
T6	289-452	Sentence	denotes	Here, we combined the PASylation technology with enzymatic in situ N-acetylation by RimJ to produce a long-acting version of Tα1 in Escherichia coli at high yield.