PMC:7786642 / 20891-21827 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7786642","sourcedb":"PMC","sourceid":"7786642","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7786642","text":"In a post-hoc analysis we investigated if the evidence of an effect of NO2 on COVID-19 mortality can be attributed to pre-existing conditions. We selected hypertension, chronic obstructive pulmonary disease (COPD) and diabetes, because of 1) indications of previous literature that they increase the COVID-19 mortality risk (Williamson et al., 2020, Yang et al., 2020), 2) previous literature that suggest an effect with long-term exposure NO2 (Balti et al., 2014, Cai et al., 2016, Zhang et al., 2018) and 3) data availability. We retrieved prevalence data for these pre-existing conditions from PHE available at the GP practice level during 2018–2019 (https://fingertips.phe.org.uk/), Supplemental Material Fig. S30-32. The effect of NO2 remains similar, 0.6% (95% CrI: −0.1%, 1.3%) with the posterior probability being 0.94 whereas the spatial relative risk highlights the same geographical locations, Supplemental Material Fig. S33.","tracks":[{"project":"LitCovid-PD-HP","denotations":[{"id":"T7","span":{"begin":155,"end":167},"obj":"Phenotype"},{"id":"T8","span":{"begin":169,"end":206},"obj":"Phenotype"},{"id":"T9","span":{"begin":208,"end":212},"obj":"Phenotype"}],"attributes":[{"id":"A7","pred":"hp_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A8","pred":"hp_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/HP_0006510"},{"id":"A9","pred":"hp_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/HP_0006510"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T9","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"191","span":{"begin":71,"end":74},"obj":"Chemical"},{"id":"192","span":{"begin":673,"end":676},"obj":"Chemical"},{"id":"193","span":{"begin":736,"end":739},"obj":"Chemical"},{"id":"194","span":{"begin":78,"end":86},"obj":"Disease"},{"id":"195","span":{"begin":87,"end":96},"obj":"Disease"},{"id":"196","span":{"begin":155,"end":167},"obj":"Disease"},{"id":"197","span":{"begin":169,"end":206},"obj":"Disease"},{"id":"198","span":{"begin":208,"end":212},"obj":"Disease"},{"id":"199","span":{"begin":218,"end":226},"obj":"Disease"},{"id":"200","span":{"begin":300,"end":308},"obj":"Disease"},{"id":"201","span":{"begin":309,"end":318},"obj":"Disease"}],"attributes":[{"id":"A192","pred":"tao:has_database_id","subj":"192","obj":"MESH:D010649"},{"id":"A194","pred":"tao:has_database_id","subj":"194","obj":"MESH:C000657245"},{"id":"A195","pred":"tao:has_database_id","subj":"195","obj":"MESH:D003643"},{"id":"A196","pred":"tao:has_database_id","subj":"196","obj":"MESH:D006973"},{"id":"A197","pred":"tao:has_database_id","subj":"197","obj":"MESH:D029424"},{"id":"A198","pred":"tao:has_database_id","subj":"198","obj":"MESH:D029424"},{"id":"A199","pred":"tao:has_database_id","subj":"199","obj":"MESH:D003920"},{"id":"A200","pred":"tao:has_database_id","subj":"200","obj":"MESH:C000657245"},{"id":"A201","pred":"tao:has_database_id","subj":"201","obj":"MESH:D003643"},{"subj":"191","pred":"source","obj":"LitCovid-PubTator"},{"subj":"192","pred":"source","obj":"LitCovid-PubTator"},{"subj":"193","pred":"source","obj":"LitCovid-PubTator"},{"subj":"194","pred":"source","obj":"LitCovid-PubTator"},{"subj":"195","pred":"source","obj":"LitCovid-PubTator"},{"subj":"196","pred":"source","obj":"LitCovid-PubTator"},{"subj":"197","pred":"source","obj":"LitCovid-PubTator"},{"subj":"198","pred":"source","obj":"LitCovid-PubTator"},{"subj":"199","pred":"source","obj":"LitCovid-PubTator"},{"subj":"200","pred":"source","obj":"LitCovid-PubTator"},{"subj":"201","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T179","span":{"begin":0,"end":142},"obj":"Sentence"},{"id":"T180","span":{"begin":143,"end":528},"obj":"Sentence"},{"id":"T181","span":{"begin":529,"end":721},"obj":"Sentence"},{"id":"T182","span":{"begin":722,"end":936},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T179","pred":"source","obj":"LitCovid-sentences"},{"subj":"T180","pred":"source","obj":"LitCovid-sentences"},{"subj":"T181","pred":"source","obj":"LitCovid-sentences"},{"subj":"T182","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-HP","color":"#a393ec","default":true},{"id":"LitCovid-PubTator","color":"#9cec93"},{"id":"LitCovid-sentences","color":"#ec93b6"}]}]}}