PMC:7784834 / 24262-24930 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"325","span":{"begin":25,"end":33},"obj":"Chemical"},{"id":"333","span":{"begin":255,"end":257},"obj":"CellLine"},{"id":"334","span":{"begin":342,"end":344},"obj":"CellLine"},{"id":"335","span":{"begin":471,"end":475},"obj":"CellLine"},{"id":"336","span":{"begin":519,"end":523},"obj":"CellLine"},{"id":"337","span":{"begin":565,"end":567},"obj":"CellLine"},{"id":"338","span":{"begin":610,"end":612},"obj":"CellLine"},{"id":"339","span":{"begin":656,"end":658},"obj":"CellLine"}],"attributes":[{"id":"A325","pred":"tao:has_database_id","subj":"325","obj":"MESH:D006859"},{"id":"A333","pred":"tao:has_database_id","subj":"333","obj":"CVCL:M698"},{"id":"A334","pred":"tao:has_database_id","subj":"334","obj":"CVCL:M698"},{"id":"A335","pred":"tao:has_database_id","subj":"335","obj":"CVCL:B526"},{"id":"A336","pred":"tao:has_database_id","subj":"336","obj":"CVCL:B526"},{"id":"A337","pred":"tao:has_database_id","subj":"337","obj":"CVCL:M698"},{"id":"A338","pred":"tao:has_database_id","subj":"338","obj":"CVCL:M698"},{"id":"A339","pred":"tao:has_database_id","subj":"339","obj":"CVCL:M698"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Table 2. Intermolecular hydrogen bonds and hydrophobic residues showing close contact between main protease with Rutin.\nMain protease + rutin\nInteracting residue H-bond distance (Å) H-bond (D-H--A) Hydrophobic residues\nTHR 26.A O–Rutin.het O15 3.05 HO-H--O15 Thr25, Leu27, His41, Met49, Gly143, His164,\nTHR 26.A O–Rutin.het O16 3.02 HO-H--O16 Met165, Leu167, Pro168, Arg188,\nTYR 54.A OH–Rutin.het O14 2.91 HOH-H--O14 Gln189\nASN 142.A OD1–Rutin.het O5 3.01 HOD1-H--O5  \nASN 142.A OD1–Rutin.het O7 2.91 HOD1-H--O7  \nGLU 166.A O–Rutin.het O8 3.02 HO-H--O8  \nASP 187.A O–Rutin.het O14 3.31 HO-H--O14  \nTHR 190.A O–Rutin.het O10 2.87 HO-H--O10  "}

{"project":"LitCovid-sentences","denotations":[{"id":"T168","span":{"begin":0,"end":8},"obj":"Sentence"},{"id":"T169","span":{"begin":10,"end":120},"obj":"Sentence"},{"id":"T170","span":{"begin":121,"end":142},"obj":"Sentence"},{"id":"T171","span":{"begin":143,"end":222},"obj":"Sentence"},{"id":"T172","span":{"begin":223,"end":309},"obj":"Sentence"},{"id":"T173","span":{"begin":310,"end":384},"obj":"Sentence"},{"id":"T174","span":{"begin":385,"end":436},"obj":"Sentence"},{"id":"T175","span":{"begin":437,"end":484},"obj":"Sentence"},{"id":"T176","span":{"begin":485,"end":532},"obj":"Sentence"},{"id":"T177","span":{"begin":533,"end":576},"obj":"Sentence"},{"id":"T178","span":{"begin":577,"end":622},"obj":"Sentence"},{"id":"T179","span":{"begin":623,"end":668},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Table 2. Intermolecular hydrogen bonds and hydrophobic residues showing close contact between main protease with Rutin.\nMain protease + rutin\nInteracting residue H-bond distance (Å) H-bond (D-H--A) Hydrophobic residues\nTHR 26.A O–Rutin.het O15 3.05 HO-H--O15 Thr25, Leu27, His41, Met49, Gly143, His164,\nTHR 26.A O–Rutin.het O16 3.02 HO-H--O16 Met165, Leu167, Pro168, Arg188,\nTYR 54.A OH–Rutin.het O14 2.91 HOH-H--O14 Gln189\nASN 142.A OD1–Rutin.het O5 3.01 HOD1-H--O5  \nASN 142.A OD1–Rutin.het O7 2.91 HOD1-H--O7  \nGLU 166.A O–Rutin.het O8 3.02 HO-H--O8  \nASP 187.A O–Rutin.het O14 3.31 HO-H--O14  \nTHR 190.A O–Rutin.het O10 2.87 HO-H--O10  "}