PMC:7784830 / 26017-27554 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"429","span":{"begin":869,"end":872},"obj":"Gene"},{"id":"430","span":{"begin":267,"end":279},"obj":"Species"},{"id":"431","span":{"begin":1071,"end":1079},"obj":"Species"},{"id":"432","span":{"begin":108,"end":112},"obj":"Chemical"},{"id":"433","span":{"begin":707,"end":710},"obj":"Disease"},{"id":"434","span":{"begin":843,"end":849},"obj":"Disease"},{"id":"435","span":{"begin":985,"end":988},"obj":"Disease"},{"id":"436","span":{"begin":1064,"end":1070},"obj":"Disease"},{"id":"437","span":{"begin":1123,"end":1150},"obj":"Disease"}],"attributes":[{"id":"A429","pred":"tao:has_database_id","subj":"429","obj":"Gene:7490"},{"id":"A430","pred":"tao:has_database_id","subj":"430","obj":"Tax:11118"},{"id":"A431","pred":"tao:has_database_id","subj":"431","obj":"Tax:9606"},{"id":"A433","pred":"tao:has_database_id","subj":"433","obj":"MESH:C537262"},{"id":"A434","pred":"tao:has_database_id","subj":"434","obj":"MESH:D009369"},{"id":"A435","pred":"tao:has_database_id","subj":"435","obj":"MESH:C537262"},{"id":"A436","pred":"tao:has_database_id","subj":"436","obj":"MESH:D009369"},{"id":"A437","pred":"tao:has_database_id","subj":"437","obj":"MESH:D006069"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Table 6. Antiviral vaccines that are formulated as ODFs.\nName of the player Name of vaccine formulated as ODFs Polymer Plasticizer Method employed Key highlight(s) Ref.\nThe Johns Hopkins University Several live-attenuated viruses were proposed, including the corona virus. Provided methodology to prepare rotavirus vaccine Eudragit Polyethylene glycol (PEG) and polyvinyl alcohol (PVA) Double emulsion solvent evaporation Prepared as monolayered or bi layered ODFs [126]\nBrian Pulliam (single applicant and inventor) Rotavirus vaccine along with an antacid namely magnesium hydroxide or aluminum hydroxide nanoparticles for digestion purpose Polyvinyl pyrrolidone +  hydroxypropyl cellulose (HPC) PEG Solvent casting method (SCM) Antacid successfully combined with a vaccine in layered fashion [22]\nNitto Denko Corporation Cancer vaccine comprising WT1 peptide or Db126 along with a promoter namely lipopolysaccharide or quercetin or ioxoprofen Mannitol, PEG, and HPC PEG, mannitol SCM Composition successfully induces cellular immunity in cancer patients [127]\nNasir Uddin from Larkin University Gonorrhoea microparticulate vaccine a a SCM Microparticulate vaccine particles were obtained by spray dryingBilayered ODFs can be prepared, outer layer acts as protection layer [128]\nAridis Pharmaceuticals Rotavirus vaccine a a a Patent protected vaccine stabilization technology and plasticized glass stabilization technology were employed in preparing the vaccine film [129–131]\na Nothing found."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T9","span":{"begin":843,"end":849},"obj":"Phenotype"},{"id":"T10","span":{"begin":1064,"end":1070},"obj":"Phenotype"}],"attributes":[{"id":"A9","pred":"hp_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/HP_0002664"},{"id":"A10","pred":"hp_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/HP_0002664"}],"text":"Table 6. Antiviral vaccines that are formulated as ODFs.\nName of the player Name of vaccine formulated as ODFs Polymer Plasticizer Method employed Key highlight(s) Ref.\nThe Johns Hopkins University Several live-attenuated viruses were proposed, including the corona virus. Provided methodology to prepare rotavirus vaccine Eudragit Polyethylene glycol (PEG) and polyvinyl alcohol (PVA) Double emulsion solvent evaporation Prepared as monolayered or bi layered ODFs [126]\nBrian Pulliam (single applicant and inventor) Rotavirus vaccine along with an antacid namely magnesium hydroxide or aluminum hydroxide nanoparticles for digestion purpose Polyvinyl pyrrolidone +  hydroxypropyl cellulose (HPC) PEG Solvent casting method (SCM) Antacid successfully combined with a vaccine in layered fashion [22]\nNitto Denko Corporation Cancer vaccine comprising WT1 peptide or Db126 along with a promoter namely lipopolysaccharide or quercetin or ioxoprofen Mannitol, PEG, and HPC PEG, mannitol SCM Composition successfully induces cellular immunity in cancer patients [127]\nNasir Uddin from Larkin University Gonorrhoea microparticulate vaccine a a SCM Microparticulate vaccine particles were obtained by spray dryingBilayered ODFs can be prepared, outer layer acts as protection layer [128]\nAridis Pharmaceuticals Rotavirus vaccine a a a Patent protected vaccine stabilization technology and plasticized glass stabilization technology were employed in preparing the vaccine film [129–131]\na Nothing found."}

{"project":"LitCovid-sentences","denotations":[{"id":"T204","span":{"begin":0,"end":8},"obj":"Sentence"},{"id":"T205","span":{"begin":10,"end":57},"obj":"Sentence"},{"id":"T206","span":{"begin":58,"end":175},"obj":"Sentence"},{"id":"T207","span":{"begin":176,"end":280},"obj":"Sentence"},{"id":"T208","span":{"begin":281,"end":483},"obj":"Sentence"},{"id":"T209","span":{"begin":484,"end":817},"obj":"Sentence"},{"id":"T210","span":{"begin":818,"end":1086},"obj":"Sentence"},{"id":"T211","span":{"begin":1087,"end":1312},"obj":"Sentence"},{"id":"T212","span":{"begin":1313,"end":1519},"obj":"Sentence"},{"id":"T213","span":{"begin":1520,"end":1537},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Table 6. Antiviral vaccines that are formulated as ODFs.\nName of the player Name of vaccine formulated as ODFs Polymer Plasticizer Method employed Key highlight(s) Ref.\nThe Johns Hopkins University Several live-attenuated viruses were proposed, including the corona virus. Provided methodology to prepare rotavirus vaccine Eudragit Polyethylene glycol (PEG) and polyvinyl alcohol (PVA) Double emulsion solvent evaporation Prepared as monolayered or bi layered ODFs [126]\nBrian Pulliam (single applicant and inventor) Rotavirus vaccine along with an antacid namely magnesium hydroxide or aluminum hydroxide nanoparticles for digestion purpose Polyvinyl pyrrolidone +  hydroxypropyl cellulose (HPC) PEG Solvent casting method (SCM) Antacid successfully combined with a vaccine in layered fashion [22]\nNitto Denko Corporation Cancer vaccine comprising WT1 peptide or Db126 along with a promoter namely lipopolysaccharide or quercetin or ioxoprofen Mannitol, PEG, and HPC PEG, mannitol SCM Composition successfully induces cellular immunity in cancer patients [127]\nNasir Uddin from Larkin University Gonorrhoea microparticulate vaccine a a SCM Microparticulate vaccine particles were obtained by spray dryingBilayered ODFs can be prepared, outer layer acts as protection layer [128]\nAridis Pharmaceuticals Rotavirus vaccine a a a Patent protected vaccine stabilization technology and plasticized glass stabilization technology were employed in preparing the vaccine film [129–131]\na Nothing found."}