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PMC:7784829 / 3294-4524 JSONTXT

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LitCovid-sentences

Id Subject Object Predicate Lexical cue
T30 0-126 Sentence denotes SARS-CoV-2 has a genome of ∼30 kilobases, which codes for multiple structural and non-structural proteins (Chan et al., 2020).
T31 127-316 Sentence denotes The structural proteins, present on the surface of the mature virion, include the spike protein, the membrane protein, the envelope protein and the nucleocapsid protein (Chan et al., 2020).
T32 317-536 Sentence denotes The Spike protein, of the beta coronaviruses SARS-CoV-2 and SARS-CoV, enables the attachment of the virus to the cells of the lower respiratory tract of humans to gain entry into the lung tissue (Hoffmann et al., 2020).
T33 537-701 Sentence denotes Apart from attachment, the spike glycoprotein also appears to play a role in fusion and entry of the virus into the host (Chen et al., 2020; Hoffmann et al., 2020).
T34 702-886 Sentence denotes The spike protein, of the novel coronavirus, utilizes the SARS-CoV receptor, ACE2 for entry (Chen et al., 2020) and is primed by the cellular protease, TMPRSS2 (Hoffmann et al., 2020).
T35 887-1016 Sentence denotes A serine protease inhibitor, which can act on TMPRSS2, has been shown to inhibit novel coronavirus entry (Hoffmann et al., 2020).
T36 1017-1230 Sentence denotes Therefore, the spike protein of the novel coronavirus is a good drug target and identifying small molecules that bind to S protein would inhibit viral recognition of host cells and disrupt viral-host interactions.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
104 209-214 Gene denotes spike Gene:43740568
105 250-266 Gene denotes envelope protein Gene:64006
106 321-326 Gene denotes Spike Gene:43740568
107 706-711 Gene denotes spike Gene:43740568
108 779-783 Gene denotes ACE2 Gene:59272
109 854-861 Gene denotes TMPRSS2 Gene:7113
110 933-940 Gene denotes TMPRSS2 Gene:7113
111 1032-1037 Gene denotes spike Gene:43740568
112 0-10 Species denotes SARS-CoV-2 Tax:2697049
113 343-361 Species denotes beta coronaviruses Tax:694002
114 362-372 Species denotes SARS-CoV-2 Tax:2697049
115 377-385 Species denotes SARS-CoV Tax:694009
116 470-476 Species denotes humans Tax:9606
117 728-745 Species denotes novel coronavirus Tax:2697049
118 760-768 Species denotes SARS-CoV Tax:694009
119 968-985 Species denotes novel coronavirus Tax:2697049
120 1053-1070 Species denotes novel coronavirus Tax:2697049
121 889-895 Chemical denotes serine MESH:D012694