PMC:7784829 / 25606-26386 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T281	0-517	Sentence	denotes	[a] Abbreviations: WS—Water solubility (log mol/L), CP—Caco2 permeability (log Papp in 10-6 cm/s), IA—Human intestinal absorption (% Absorbed), SP—Skin permeability (log Kp),PI-1—P-glycoprotein I inhibitor, PI-2—P-glycoprotein II inhibitor, VD—Human volume ofdistribution (log L/kg), FU—Fraction unbound (human) (Fu), BBB—BBB permeability (logBB), CNS—CNS permeability (log PS), CI-1—CYP3A4 inhibitor, CI-2—CYP2C9 inhibitor,TC—Total clearance (log mL/min/kg), RS—Renal OCT2 (organic cation transporter 2) substrate.
T282	518-523	Sentence	denotes	BHBC:
T283	524-578	Sentence	denotes	3-5-di-tert-butyl-4-hydroxybenzaldehyde curcumin, MNC:
T284	579-621	Sentence	denotes	4-methoxy-1-naphthaldehyde curcumin, BDMC:
T285	622-650	Sentence	denotes	Bis-demethoxy curcumin, DMC:
T286	651-675	Sentence	denotes	Demethoxy curcumin, FAC:
T287	676-703	Sentence	denotes	Ferulic-acid curcumin, IBC:
T288	704-728	Sentence	denotes	Ibuprofen curcumin, IVC:
T289	729-755	Sentence	denotes	Isovanillin curcumin, SYC:
T290	756-780	Sentence	denotes	Syringaldehyde curcumin.

Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
683	181-195	Gene	denotes	P-glycoprotein	Gene:5243
684	386-392	Gene	denotes	CYP3A4	Gene:1576
685	409-415	Gene	denotes	CYP2C9	Gene:1559
686	471-475	Gene	denotes	OCT2	Gene:6582
687	477-505	Gene	denotes	organic cation transporter 2	Gene:6582
688	104-109	Species	denotes	Human	Tax:9606
689	209-213	Species	denotes	PI-2	Tax:1214577
690	246-251	Species	denotes	Human	Tax:9606
691	307-312	Species	denotes	human	Tax:9606
692	214-228	Gene	denotes	P-glycoprotein	Gene:5243
693	24-29	Chemical	denotes	Water	MESH:D014867
694	518-522	Chemical	denotes	BHBC
695	524-563	Chemical	denotes	3-5-di-tert-butyl-4-hydroxybenzaldehyde	MESH:C513957
696	564-572	Chemical	denotes	curcumin	MESH:D003474
697	574-577	Chemical	denotes	MNC
698	579-605	Chemical	denotes	4-methoxy-1-naphthaldehyde
699	606-614	Chemical	denotes	curcumin	MESH:D003474
700	616-620	Chemical	denotes	BDMC
701	622-644	Chemical	denotes	Bis-demethoxy curcumin	MESH:C034786
702	651-669	Chemical	denotes	Demethoxy curcumin	MESH:C050229
703	676-688	Chemical	denotes	Ferulic-acid	MESH:C004999
704	689-697	Chemical	denotes	curcumin	MESH:D003474
705	699-702	Chemical	denotes	IBC	MESH:D002015
706	704-722	Chemical	denotes	Ibuprofen curcumin
707	729-749	Chemical	denotes	Isovanillin curcumin
708	756-770	Chemical	denotes	Syringaldehyde	MESH:C069665
709	771-779	Chemical	denotes	curcumin	MESH:D003474