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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7784828","sourcedb":"PMC","sourceid":"7784828","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7784828","text":"2.1.2. Cancer\nCancer remains as the second leading cause of mortality worldwide. In 2018, cancer have affected an estimated 18.1 million people and caused 9.6 million deaths [17]. A close watch at the statistics reveals that cancer kills around 10 million people every year; which is about 20,000 people every day; that correlates to one person every second. The number of cancer deaths in the United States alone is predicted to increase to 946,833 in 2030 from 595,690 in 2016 [18]. These disturbing figures desperately calls for the need to develop early diagnostics, novel, and effective medicines as well as new drug development strategies. Partial solutions to this challenge by precision medicine and immunotherapy has been firmly established, merits to the recent inventions in cancer genomics and immunology 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