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PMC:7784828 / 3987-8487 JSONTXT

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LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T3 2390-2396 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664
T4 2397-2403 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664
T5 2473-2479 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T6 2608-2614 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T7 2756-2762 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T8 3169-3175 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T9 3317-3325 Phenotype denotes Dementia http://purl.obolibrary.org/obo/HP_0000726
T10 3342-3350 Phenotype denotes dementia http://purl.obolibrary.org/obo/HP_0000726
T11 3500-3506 Phenotype denotes stroke http://purl.obolibrary.org/obo/HP_0001297
T12 3590-3598 Phenotype denotes dementia http://purl.obolibrary.org/obo/HP_0000726
T13 3789-3808 Phenotype denotes Alzheimer’s disease http://purl.obolibrary.org/obo/HP_0002511

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T40 0-4 Sentence denotes 2.1.
T41 6-38 Sentence denotes Alarming pace of deadly diseases
T42 39-147 Sentence denotes Death rates due to diseases largely depend on access to health care and availability of effective medicines.
T43 148-294 Sentence denotes The vast majority of the deadliest diseases are partially preventable with better access to preventive procedures and quality healthcare delivery.
T44 295-484 Sentence denotes With the advancements in medical sciences, we have seen a drastic reduction in death rates for many devastating diseases in developed nations and to a lesser extent in developing countries.
T45 485-585 Sentence denotes A brief summary of the global medical challenges the humankind continues to face is presented below.
T46 587-593 Sentence denotes 2.1.1.
T47 595-614 Sentence denotes Infectious diseases
T48 615-671 Sentence denotes Malaria is an ancient scourge as old as humanity itself.
T49 672-771 Sentence denotes There are over 200 million new infections and around half a million deaths reported every year [5].
T50 772-910 Sentence denotes Despite many attempts to design effective vaccines, none has been successful at providing long-lasting benefits at a population level [9].
T51 911-1092 Sentence denotes Tuberculosis (TB) remains one of the top 10 causes of death worldwide, with 10,000 million infections and 1.5 million deaths in 2018 according to the world health organization [10].
T52 1093-1174 Sentence denotes Likewise, viruses continue to compromise the lives of tens of millions of people.
T53 1175-1320 Sentence denotes Globally, influenza virus infects a 1 billion people and causes up to 650,000 deaths every year despite the availability of the flu vaccine [11].
T54 1321-1425 Sentence denotes Viral infections inflect heavy societal and economic burdens beside their morbidity and mortality tolls.
T55 1426-1689 Sentence denotes The past half century has witnessed deadly outbreaks of novel viruses of animal origin other than SARS-CoV2 such as Nipah, Hendra, Hanta, Ebola, several influenza subtypes, SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome) [12].
T56 1690-1896 Sentence denotes These outbreaks warn the urgency of understanding the factors influencing viral diseases emergence and spread as well as global preparedness to halt these epidemics from becoming a full-blown pandemic [13].
T57 1897-1975 Sentence denotes Multidrug resistance is yet another emergent global public health threat [14].
T58 1976-2183 Sentence denotes The emergence and spread of antimicrobial resistance (AMR) among bacterial pathogen are responsible for more than 700,000 deaths per year, and is projected to cause a 10 million deaths per year by 2050 [15].
T59 2184-2380 Sentence denotes The World Health Organization along with several other organization have called an urgent action to tackle the spread of antimicrobial resistance and invest in development of new antibiotics [16].
T60 2382-2388 Sentence denotes 2.1.2.
T61 2390-2396 Sentence denotes Cancer
T62 2397-2463 Sentence denotes Cancer remains as the second leading cause of mortality worldwide.
T63 2464-2562 Sentence denotes In 2018, cancer have affected an estimated 18.1 million people and caused 9.6 million deaths [17].
T64 2563-2741 Sentence denotes A close watch at the statistics reveals that cancer kills around 10 million people every year; which is about 20,000 people every day; that correlates to one person every second.
T65 2742-2867 Sentence denotes The number of cancer deaths in the United States alone is predicted to increase to 946,833 in 2030 from 595,690 in 2016 [18].
T66 2868-3028 Sentence denotes These disturbing figures desperately calls for the need to develop early diagnostics, novel, and effective medicines as well as new drug development strategies.
T67 3029-3205 Sentence denotes Partial solutions to this challenge by precision medicine and immunotherapy has been firmly established, merits to the recent inventions in cancer genomics and immunology [18].
T68 3207-3213 Sentence denotes 2.1.3.
T69 3215-3227 Sentence denotes CNS diseases
T70 3228-3331 Sentence denotes Another significant growing healthcare need with a major economic and medical impacts is Dementia [19].
T71 3332-3547 Sentence denotes Globally, dementia affects around 50 million people, and over the past 18 years, the percentage of death among Alzheimer’s patients doubled while deaths resulting from stroke, and heart diseases have decreased [20].
T72 3548-3714 Sentence denotes In the US alone the number of Alzheimer’s dementia cases is expected to shoot up to 13.8 million and impose a health care burden of 1.1 trillion dollars by 2050 [20].
T73 3715-3814 Sentence denotes As of today, there are no medications known to reverse the progression of Alzheimer’s disease [21].
T74 3816-3822 Sentence denotes 2.1.4.
T75 3824-3837 Sentence denotes Rare diseases
T76 3838-3961 Sentence denotes Although individual occurrence is rare, collectively rare diseases is a problem affecting 6–8% of the world population [7].
T77 3962-4100 Sentence denotes The Rare Diseases Clinical Research Network was established by The National Institutes of Health (NIH) to address these unique challenges.
T78 4101-4169 Sentence denotes Among the 7,000 rare diseases, treatments are available only for 5%.
T79 4170-4332 Sentence denotes Altogether across the globe, there are 350 million people diagnosed with rare diseases and half of them are children, a third of which are below 5-years old [22].
T80 4333-4500 Sentence denotes There is a great disparity in access to orphan medicinal products (OMPs) and healthcare services among world countries despite mounting international initiatives [23].

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
21 23-38 Disease denotes deadly diseases MESH:D003141
24 39-44 Disease denotes Death MESH:D003643
25 374-379 Disease denotes death MESH:D003643
27 595-614 Disease denotes Infectious diseases MESH:D003141
51 1167-1173 Species denotes people Tax:9606
52 1185-1200 Species denotes influenza virus Tax:11309
53 1221-1227 Species denotes people Tax:9606
54 1303-1314 Species denotes flu vaccine Tax:335812
55 1524-1533 Species denotes SARS-CoV2 Tax:2697049
56 1564-1569 Species denotes Ebola Tax:1570291
57 1579-1588 Species denotes influenza Tax:11309
58 615-622 Disease denotes Malaria MESH:D008288
59 703-713 Disease denotes infections MESH:D007239
60 740-746 Disease denotes deaths MESH:D003643
61 911-923 Disease denotes Tuberculosis MESH:D014376
62 965-970 Disease denotes death MESH:D003643
63 1002-1012 Disease denotes infections MESH:D007239
64 1029-1035 Disease denotes deaths MESH:D003643
65 1253-1259 Disease denotes deaths MESH:D003643
66 1321-1337 Disease denotes Viral infections MESH:D001102
67 1409-1418 Disease denotes mortality MESH:D003643
68 1605-1638 Disease denotes Severe Acute Respiratory Syndrome MESH:D045169
69 1644-1648 Disease denotes MERS MESH:D018352
70 1650-1682 Disease denotes Middle East Respiratory Syndrome MESH:D018352
71 1764-1778 Disease denotes viral diseases MESH:D001102
72 2098-2104 Disease denotes deaths MESH:D003643
73 2154-2160 Disease denotes deaths MESH:D003643
75 2390-2396 Disease denotes Cancer MESH:D009369
86 2520-2526 Species denotes people Tax:9606
87 2639-2645 Species denotes people Tax:9606
88 2680-2686 Species denotes people Tax:9606
89 2397-2403 Disease denotes Cancer MESH:D009369
90 2443-2452 Disease denotes mortality MESH:D003643
91 2473-2479 Disease denotes cancer MESH:D009369
92 2550-2556 Disease denotes deaths MESH:D003643
93 2608-2614 Disease denotes cancer MESH:D009369
94 2756-2769 Disease denotes cancer deaths MESH:D009369
95 3169-3175 Disease denotes cancer MESH:D009369
97 3215-3227 Disease denotes CNS diseases MESH:D002493
108 3377-3383 Species denotes people Tax:9606
109 3455-3463 Species denotes patients Tax:9606
110 3342-3350 Disease denotes dementia MESH:D003704
111 3431-3436 Disease denotes death MESH:D003643
112 3443-3454 Disease denotes Alzheimer’s MESH:D000544
113 3478-3484 Disease denotes deaths MESH:D003643
114 3500-3506 Disease denotes stroke MESH:D020521
115 3512-3526 Disease denotes heart diseases MESH:D006331
116 3578-3598 Disease denotes Alzheimer’s dementia MESH:D000544
117 3789-3808 Disease denotes Alzheimer’s disease MESH:D000544
120 4221-4227 Species denotes people Tax:9606
121 4278-4286 Species denotes children Tax:9606