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PMC:7784828 / 3970-8487 JSONTXT

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LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T3 2407-2413 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664
T4 2414-2420 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664
T5 2490-2496 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T6 2625-2631 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T7 2773-2779 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T8 3186-3192 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T9 3334-3342 Phenotype denotes Dementia http://purl.obolibrary.org/obo/HP_0000726
T10 3359-3367 Phenotype denotes dementia http://purl.obolibrary.org/obo/HP_0000726
T11 3517-3523 Phenotype denotes stroke http://purl.obolibrary.org/obo/HP_0001297
T12 3607-3615 Phenotype denotes dementia http://purl.obolibrary.org/obo/HP_0000726
T13 3806-3825 Phenotype denotes Alzheimer’s disease http://purl.obolibrary.org/obo/HP_0002511

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T38 0-2 Sentence denotes 2.
T39 4-15 Sentence denotes Unmet needs
T40 17-21 Sentence denotes 2.1.
T41 23-55 Sentence denotes Alarming pace of deadly diseases
T42 56-164 Sentence denotes Death rates due to diseases largely depend on access to health care and availability of effective medicines.
T43 165-311 Sentence denotes The vast majority of the deadliest diseases are partially preventable with better access to preventive procedures and quality healthcare delivery.
T44 312-501 Sentence denotes With the advancements in medical sciences, we have seen a drastic reduction in death rates for many devastating diseases in developed nations and to a lesser extent in developing countries.
T45 502-602 Sentence denotes A brief summary of the global medical challenges the humankind continues to face is presented below.
T46 604-610 Sentence denotes 2.1.1.
T47 612-631 Sentence denotes Infectious diseases
T48 632-688 Sentence denotes Malaria is an ancient scourge as old as humanity itself.
T49 689-788 Sentence denotes There are over 200 million new infections and around half a million deaths reported every year [5].
T50 789-927 Sentence denotes Despite many attempts to design effective vaccines, none has been successful at providing long-lasting benefits at a population level [9].
T51 928-1109 Sentence denotes Tuberculosis (TB) remains one of the top 10 causes of death worldwide, with 10,000 million infections and 1.5 million deaths in 2018 according to the world health organization [10].
T52 1110-1191 Sentence denotes Likewise, viruses continue to compromise the lives of tens of millions of people.
T53 1192-1337 Sentence denotes Globally, influenza virus infects a 1 billion people and causes up to 650,000 deaths every year despite the availability of the flu vaccine [11].
T54 1338-1442 Sentence denotes Viral infections inflect heavy societal and economic burdens beside their morbidity and mortality tolls.
T55 1443-1706 Sentence denotes The past half century has witnessed deadly outbreaks of novel viruses of animal origin other than SARS-CoV2 such as Nipah, Hendra, Hanta, Ebola, several influenza subtypes, SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome) [12].
T56 1707-1913 Sentence denotes These outbreaks warn the urgency of understanding the factors influencing viral diseases emergence and spread as well as global preparedness to halt these epidemics from becoming a full-blown pandemic [13].
T57 1914-1992 Sentence denotes Multidrug resistance is yet another emergent global public health threat [14].
T58 1993-2200 Sentence denotes The emergence and spread of antimicrobial resistance (AMR) among bacterial pathogen are responsible for more than 700,000 deaths per year, and is projected to cause a 10 million deaths per year by 2050 [15].
T59 2201-2397 Sentence denotes The World Health Organization along with several other organization have called an urgent action to tackle the spread of antimicrobial resistance and invest in development of new antibiotics [16].
T60 2399-2405 Sentence denotes 2.1.2.
T61 2407-2413 Sentence denotes Cancer
T62 2414-2480 Sentence denotes Cancer remains as the second leading cause of mortality worldwide.
T63 2481-2579 Sentence denotes In 2018, cancer have affected an estimated 18.1 million people and caused 9.6 million deaths [17].
T64 2580-2758 Sentence denotes A close watch at the statistics reveals that cancer kills around 10 million people every year; which is about 20,000 people every day; that correlates to one person every second.
T65 2759-2884 Sentence denotes The number of cancer deaths in the United States alone is predicted to increase to 946,833 in 2030 from 595,690 in 2016 [18].
T66 2885-3045 Sentence denotes These disturbing figures desperately calls for the need to develop early diagnostics, novel, and effective medicines as well as new drug development strategies.
T67 3046-3222 Sentence denotes Partial solutions to this challenge by precision medicine and immunotherapy has been firmly established, merits to the recent inventions in cancer genomics and immunology [18].
T68 3224-3230 Sentence denotes 2.1.3.
T69 3232-3244 Sentence denotes CNS diseases
T70 3245-3348 Sentence denotes Another significant growing healthcare need with a major economic and medical impacts is Dementia [19].
T71 3349-3564 Sentence denotes Globally, dementia affects around 50 million people, and over the past 18 years, the percentage of death among Alzheimer’s patients doubled while deaths resulting from stroke, and heart diseases have decreased [20].
T72 3565-3731 Sentence denotes In the US alone the number of Alzheimer’s dementia cases is expected to shoot up to 13.8 million and impose a health care burden of 1.1 trillion dollars by 2050 [20].
T73 3732-3831 Sentence denotes As of today, there are no medications known to reverse the progression of Alzheimer’s disease [21].
T74 3833-3839 Sentence denotes 2.1.4.
T75 3841-3854 Sentence denotes Rare diseases
T76 3855-3978 Sentence denotes Although individual occurrence is rare, collectively rare diseases is a problem affecting 6–8% of the world population [7].
T77 3979-4117 Sentence denotes The Rare Diseases Clinical Research Network was established by The National Institutes of Health (NIH) to address these unique challenges.
T78 4118-4186 Sentence denotes Among the 7,000 rare diseases, treatments are available only for 5%.
T79 4187-4349 Sentence denotes Altogether across the globe, there are 350 million people diagnosed with rare diseases and half of them are children, a third of which are below 5-years old [22].
T80 4350-4517 Sentence denotes There is a great disparity in access to orphan medicinal products (OMPs) and healthcare services among world countries despite mounting international initiatives [23].

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
21 40-55 Disease denotes deadly diseases MESH:D003141
24 56-61 Disease denotes Death MESH:D003643
25 391-396 Disease denotes death MESH:D003643
27 612-631 Disease denotes Infectious diseases MESH:D003141
51 1184-1190 Species denotes people Tax:9606
52 1202-1217 Species denotes influenza virus Tax:11309
53 1238-1244 Species denotes people Tax:9606
54 1320-1331 Species denotes flu vaccine Tax:335812
55 1541-1550 Species denotes SARS-CoV2 Tax:2697049
56 1581-1586 Species denotes Ebola Tax:1570291
57 1596-1605 Species denotes influenza Tax:11309
58 632-639 Disease denotes Malaria MESH:D008288
59 720-730 Disease denotes infections MESH:D007239
60 757-763 Disease denotes deaths MESH:D003643
61 928-940 Disease denotes Tuberculosis MESH:D014376
62 982-987 Disease denotes death MESH:D003643
63 1019-1029 Disease denotes infections MESH:D007239
64 1046-1052 Disease denotes deaths MESH:D003643
65 1270-1276 Disease denotes deaths MESH:D003643
66 1338-1354 Disease denotes Viral infections MESH:D001102
67 1426-1435 Disease denotes mortality MESH:D003643
68 1622-1655 Disease denotes Severe Acute Respiratory Syndrome MESH:D045169
69 1661-1665 Disease denotes MERS MESH:D018352
70 1667-1699 Disease denotes Middle East Respiratory Syndrome MESH:D018352
71 1781-1795 Disease denotes viral diseases MESH:D001102
72 2115-2121 Disease denotes deaths MESH:D003643
73 2171-2177 Disease denotes deaths MESH:D003643
75 2407-2413 Disease denotes Cancer MESH:D009369
86 2537-2543 Species denotes people Tax:9606
87 2656-2662 Species denotes people Tax:9606
88 2697-2703 Species denotes people Tax:9606
89 2414-2420 Disease denotes Cancer MESH:D009369
90 2460-2469 Disease denotes mortality MESH:D003643
91 2490-2496 Disease denotes cancer MESH:D009369
92 2567-2573 Disease denotes deaths MESH:D003643
93 2625-2631 Disease denotes cancer MESH:D009369
94 2773-2786 Disease denotes cancer deaths MESH:D009369
95 3186-3192 Disease denotes cancer MESH:D009369
97 3232-3244 Disease denotes CNS diseases MESH:D002493
108 3394-3400 Species denotes people Tax:9606
109 3472-3480 Species denotes patients Tax:9606
110 3359-3367 Disease denotes dementia MESH:D003704
111 3448-3453 Disease denotes death MESH:D003643
112 3460-3471 Disease denotes Alzheimer’s MESH:D000544
113 3495-3501 Disease denotes deaths MESH:D003643
114 3517-3523 Disease denotes stroke MESH:D020521
115 3529-3543 Disease denotes heart diseases MESH:D006331
116 3595-3615 Disease denotes Alzheimer’s dementia MESH:D000544
117 3806-3825 Disease denotes Alzheimer’s disease MESH:D000544
120 4238-4244 Species denotes people Tax:9606
121 4295-4303 Species denotes children Tax:9606