PMC:7784828 / 193-715 JSONTXT

{"project":"LitCovid-sentences","denotations":[{"id":"T8","span":{"begin":0,"end":13},"obj":"Sentence"},{"id":"T9","span":{"begin":14,"end":154},"obj":"Sentence"},{"id":"T10","span":{"begin":155,"end":221},"obj":"Sentence"},{"id":"T11","span":{"begin":222,"end":326},"obj":"Sentence"},{"id":"T12","span":{"begin":327,"end":456},"obj":"Sentence"},{"id":"T13","span":{"begin":457,"end":522},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Introduction: Despite advances in drug research and development, our knowledge of the underlying molecular mechanisms of many diseases remains inadequate. This have led to limited effective medicines for several diseases. To address these challenges, efficient strategies, novel technologies, and policies are urgently needed. The main obstacles in drug discovery and development are the mounting cost, risk, and time frame needed to develop new medicines. Fair pricing and accessibility is another unmet global challenge."}