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PMC:7784828 / 184-1603 JSONTXT

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LitCovid-sentences

Id Subject Object Predicate Lexical cue
T7 0-8 Sentence denotes ABSTRACT
T8 9-22 Sentence denotes Introduction:
T9 23-163 Sentence denotes Despite advances in drug research and development, our knowledge of the underlying molecular mechanisms of many diseases remains inadequate.
T10 164-230 Sentence denotes This have led to limited effective medicines for several diseases.
T11 231-335 Sentence denotes To address these challenges, efficient strategies, novel technologies, and policies are urgently needed.
T12 336-465 Sentence denotes The main obstacles in drug discovery and development are the mounting cost, risk, and time frame needed to develop new medicines.
T13 466-531 Sentence denotes Fair pricing and accessibility is another unmet global challenge.
T14 532-546 Sentence denotes Areas covered:
T15 547-643 Sentence denotes Here, the authors cover the pace, risks, cost, and challenges facing drug development processes.
T16 644-778 Sentence denotes Additionally, they introduce disease-associated data which demand global attention and propose solutions to overcome these challenges.
T17 779-794 Sentence denotes Expert opinion:
T18 795-932 Sentence denotes The massive challenges encountered during drug development urgently call for a serious global rethinking of the way this process is done.
T19 933-1152 Sentence denotes A partial solution might be if many consortiums of multi-nations, academic institutions, clinicians, pharma companies, and funding agencies gather at different fronts to crowdsource resources, share knowledge and risks.
T20 1153-1258 Sentence denotes Such an ecosystem can rapidly generate first-in-class molecules that are safe, effective, and affordable.
T21 1259-1419 Sentence denotes We think that this article represents a wake-up call for the scientific community to immediately reassess the current drug discovery and development procedures.