PMC:7784824 / 3788-4179 JSONTXT

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Establishing the diagnosis of COVID-19 is sometimes very challenging and does not only rely on molecular tests. We report on two patients who presented at the emergency department with high suspicion of COVID-19 infection based on clinical findings and/or chest-CT findings. Nevertheless, SARS-CoV-2 RT-PCR testing was repeatedly negative on repetitive nasopharyngeal, throat and anal swabs.