
PMC:7784786 / 15748-16527
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
562 | 38-42 | Gene | denotes | IL-6 | Gene:3569 |
563 | 140-144 | Gene | denotes | IL-6 | Gene:3569 |
564 | 287-291 | Gene | denotes | IL-6 | Gene:3569 |
565 | 391-395 | Gene | denotes | IL-6 | Gene:3569 |
566 | 186-193 | Species | denotes | patient | Tax:9606 |
567 | 734-741 | Species | denotes | patient | Tax:9606 |
568 | 346-356 | Chemical | denotes | itolizumab | MESH:C000597346 |
569 | 194-198 | Disease | denotes | died | MESH:D003643 |
570 | 232-260 | Disease | denotes | cardiovascular complications | MESH:D002318 |
571 | 602-628 | Disease | denotes | hyperinflammatory syndrome | MESH:D061325 |
572 | 630-640 | Disease | denotes | thrombosis | MESH:D013927 |
573 | 642-657 | Disease | denotes | alveolar damage | MESH:D055370 |
574 | 676-683 | Disease | denotes | hypoxia | MESH:D000860 |
575 | 742-746 | Disease | denotes | died | MESH:D003643 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T54 | 676-683 | Phenotype | denotes | hypoxia | http://purl.obolibrary.org/obo/HP_0012418 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T139 | 0-181 | Sentence | denotes | Our preliminary findings support that IL-6 levels correlated with the severity of the disease and that the antibody was capable of reducing IL-6 concentration in all three subjects. |
T140 | 182-261 | Sentence | denotes | One patient died after subsequent respiratory and cardiovascular complications. |
T141 | 262-366 | Sentence | denotes | In this particular case, IL-6 concentration was extremely elevated at the moment of itolizumab infusion. |
T142 | 367-484 | Sentence | denotes | Although, the levels of IL-6 decreased during treatment, the values at 7 days kept still very high (above 300 pg/ml). |
T143 | 485-565 | Sentence | denotes | There was a transient improvement of respiratory function but it was not enough. |
T144 | 566-779 | Sentence | denotes | Presumably, the consequences of the hyperinflammatory syndrome (thrombosis, alveolar damage and severe tissue hypoxia) were irreversible at the moment of treatment and patient died as consequence of these factors. |