PMC:7781431 / 7652-8044 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"233","span":{"begin":122,"end":127},"obj":"Gene"},{"id":"234","span":{"begin":283,"end":288},"obj":"Gene"},{"id":"235","span":{"begin":43,"end":46},"obj":"Chemical"},{"id":"236","span":{"begin":143,"end":150},"obj":"Chemical"},{"id":"237","span":{"begin":192,"end":198},"obj":"Chemical"},{"id":"238","span":{"begin":211,"end":251},"obj":"Chemical"},{"id":"239","span":{"begin":253,"end":261},"obj":"Chemical"},{"id":"240","span":{"begin":300,"end":308},"obj":"Chemical"},{"id":"241","span":{"begin":312,"end":333},"obj":"Chemical"}],"attributes":[{"id":"A233","pred":"tao:has_database_id","subj":"233","obj":"Gene:5743"},{"id":"A234","pred":"tao:has_database_id","subj":"234","obj":"Gene:240"},{"id":"A235","pred":"tao:has_database_id","subj":"235","obj":"MESH:D015118"},{"id":"A236","pred":"tao:has_database_id","subj":"236","obj":"MESH:D001241"},{"id":"A237","pred":"tao:has_database_id","subj":"237","obj":"MESH:D010100"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"RvE is a di- or tri-hydroxyl metabolite of EPA. To date, four RvEs (RvE1, 18S-RvE1, RvE2, and RvE3) have been discovered. COX-2, acetylated by aspirin in hypoxic endothelial cells, introduces oxygen groups into 18R-hydro (peroxy)-eicosapentaenoic acid (18R-HEPE). Activated PMN uses 5-LOX to convert 18R-HEPE to 5S (6)-epoxy-18R-HEPE, which is further hydrolyzed to RvE1 (Serhan et al. 2000)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T54","span":{"begin":0,"end":47},"obj":"Sentence"},{"id":"T55","span":{"begin":48,"end":121},"obj":"Sentence"},{"id":"T56","span":{"begin":122,"end":263},"obj":"Sentence"},{"id":"T57","span":{"begin":264,"end":385},"obj":"Sentence"},{"id":"T58","span":{"begin":386,"end":392},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"RvE is a di- or tri-hydroxyl metabolite of EPA. To date, four RvEs (RvE1, 18S-RvE1, RvE2, and RvE3) have been discovered. COX-2, acetylated by aspirin in hypoxic endothelial cells, introduces oxygen groups into 18R-hydro (peroxy)-eicosapentaenoic acid (18R-HEPE). Activated PMN uses 5-LOX to convert 18R-HEPE to 5S (6)-epoxy-18R-HEPE, which is further hydrolyzed to RvE1 (Serhan et al. 2000)."}