PMC:7781431 / 5807-6373 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7781431","sourcedb":"PMC","sourceid":"7781431","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7781431","text":"In vivo biosynthesis of LXA4 is triggered in an acute inflammatory process in which Polymorphonuclear neutrophil (PMN)’s interaction with PGE2 and PGD2 activates 15-lipoxygenase subsequently facilitating LXA4 biosynthesis (Claria and Serhan 1995). In a murine peritonitis model, the maximum level of LXA4 was achieved within 2 hours and gradually decreased during the first 24 hours (Bannenberg et al. 2005). The formation of LXs is preserved across a wide range of animal species, from fish to humans (Levy 2005). This indicates the physiological importance of LXs.","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"189","span":{"begin":147,"end":151},"obj":"Gene"},{"id":"190","span":{"begin":253,"end":259},"obj":"Species"},{"id":"191","span":{"begin":495,"end":501},"obj":"Species"},{"id":"192","span":{"begin":24,"end":28},"obj":"Chemical"},{"id":"193","span":{"begin":138,"end":142},"obj":"Chemical"},{"id":"194","span":{"begin":204,"end":208},"obj":"Chemical"},{"id":"195","span":{"begin":234,"end":240},"obj":"Chemical"}],"attributes":[{"id":"A189","pred":"tao:has_database_id","subj":"189","obj":"Gene:5730"},{"id":"A190","pred":"tao:has_database_id","subj":"190","obj":"Tax:10090"},{"id":"A191","pred":"tao:has_database_id","subj":"191","obj":"Tax:9606"},{"id":"A192","pred":"tao:has_database_id","subj":"192","obj":"MESH:C040527"},{"id":"A193","pred":"tao:has_database_id","subj":"193","obj":"MESH:D015232"},{"id":"A194","pred":"tao:has_database_id","subj":"194","obj":"MESH:C040527"},{"subj":"189","pred":"source","obj":"LitCovid-PubTator"},{"subj":"190","pred":"source","obj":"LitCovid-PubTator"},{"subj":"191","pred":"source","obj":"LitCovid-PubTator"},{"subj":"192","pred":"source","obj":"LitCovid-PubTator"},{"subj":"193","pred":"source","obj":"LitCovid-PubTator"},{"subj":"194","pred":"source","obj":"LitCovid-PubTator"},{"subj":"195","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T7","span":{"begin":260,"end":271},"obj":"Phenotype"}],"attributes":[{"id":"A7","pred":"hp_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/HP_0002586"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T38","span":{"begin":0,"end":247},"obj":"Sentence"},{"id":"T39","span":{"begin":248,"end":401},"obj":"Sentence"},{"id":"T40","span":{"begin":402,"end":408},"obj":"Sentence"},{"id":"T41","span":{"begin":409,"end":514},"obj":"Sentence"},{"id":"T42","span":{"begin":515,"end":566},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T38","pred":"source","obj":"LitCovid-sentences"},{"subj":"T39","pred":"source","obj":"LitCovid-sentences"},{"subj":"T40","pred":"source","obj":"LitCovid-sentences"},{"subj":"T41","pred":"source","obj":"LitCovid-sentences"},{"subj":"T42","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#ec9396","default":true},{"id":"LitCovid-PD-HP","color":"#93b0ec"},{"id":"LitCovid-sentences","color":"#caec93"}]}]}}