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PMC:7781431 / 36520-37909 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1123 854-864 Species denotes SARS-CoV-2 Tax:2697049
1124 551-570 Chemical denotes omega-3 fatty acids MESH:D015525
1125 60-72 Disease denotes inflammation MESH:D007249
1126 591-594 Disease denotes PDs
1127 807-819 Disease denotes inflammation MESH:D007249
1128 1048-1068 Disease denotes SARS-CoV-2 infection MESH:C000657245
1129 1075-1087 Disease denotes inflammation MESH:D007249
1130 1106-1118 Disease denotes inflammation MESH:D007249
1131 1245-1254 Disease denotes infection MESH:D007239

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T46 865-879 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T364 0-89 Sentence denotes Recently, a new group of molecules, named SPMs that resolve inflammation were elucidated.
T365 90-212 Sentence denotes Further, in efforts to investigate and demonstrate their mechanism of action, their receptors are slowly being discovered.
T366 213-290 Sentence denotes As an additional milestone, SPMs were detected in several biological samples.
T367 291-464 Sentence denotes However, the investigation of the pharmacological principle based on GPCR for SPMs under various physiological and pathological conditions is insufficient (Psychogios et al.
T368 465-483 Sentence denotes 2011; Lukiw et al.
T369 484-490 Sentence denotes 2005).
T370 491-605 Sentence denotes Further research is needed on specific molecular targets of omega-3 fatty acids such as RvE2, RvD2, PDs, and MaRs.
T371 606-880 Sentence denotes The interaction between the host immune system and infectious viral attacks represents new opportunities for the utilization of SPMs. The use of SPMs is likely to help regulate abnormal viral-mediated inflammation and prevent complications such as SARS-CoV-2 cytokine storm.
T372 881-963 Sentence denotes Besides, SPMs play parts in restoring tissue homeostasis, including wound healing.
T373 964-1069 Sentence denotes Therefore, they are very likely to have therapeutic effects against the sequelae of SARS-CoV-2 infection.
T374 1070-1160 Sentence denotes Both inflammation and resolution of inflammation are vital processes of the immune system.
T375 1161-1389 Sentence denotes Therefore, a balance between the need for a sufficient immune response to clear the infection and the rapid decline of immune response to prevent host damage presents a novel opportunity for therapeutic exploitation of the SPMs.