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PMC:7781431 / 34445-36506 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1058 11-58 Species denotes Severe acute respiratory syndrome Coronavirus 2 Tax:2697049
1059 60-70 Species denotes SARS-CoV-2 Tax:2697049
1060 84-95 Species denotes coronavirus Tax:11118
1061 218-231 Species denotes Coronaviridae Tax:11118
1062 298-308 Species denotes SARS-CoV-2 Tax:2697049
1063 115-139 Disease denotes 2019 coronavirus disease MESH:C000657245
1064 141-149 Disease denotes COVID-19 MESH:C000657245
1065 154-173 Disease denotes respiratory disease MESH:D012140
1066 199-207 Disease denotes COVID-19 MESH:C000657245
1067 359-365 Disease denotes deaths MESH:D003643
1091 1152-1183 Gene denotes angiotensin-converting enzyme 2 Gene:59272
1092 1185-1189 Gene denotes ACE2 Gene:59272
1093 1322-1327 Gene denotes spike Gene:43740568
1094 1329-1330 Gene denotes S Gene:43740568
1095 650-660 Species denotes SARS-CoV-2 Tax:2697049
1096 990-998 Species denotes patients Tax:9606
1097 1311-1321 Species denotes SARS-CoV-2 Tax:2697049
1098 1935-1945 Species denotes SARS-CoV-2 Tax:2697049
1099 598-602 Chemical denotes PGE2 MESH:D015232
1100 619-625 Chemical denotes lipids MESH:D008055
1101 683-699 Chemical denotes arachidonic acid MESH:D016718
1102 701-728 Chemical denotes dihomo-gamma-linolenic acid MESH:D015126
1103 734-754 Chemical denotes gamma-linolenic acid MESH:D017965
1104 1100-1109 Chemical denotes Elovanoid
1105 1226-1232 Chemical denotes lipids MESH:D008055
1106 1398-1411 Chemical denotes Elovanoid-N32
1107 1676-1684 Chemical denotes fish oil MESH:D005395
1108 825-845 Disease denotes SARS-CoV-2 infection MESH:C000657245
1109 891-900 Disease denotes infection MESH:D007239
1110 962-989 Disease denotes deficiency of SPMs in obese MESH:D009765
1111 1054-1074 Disease denotes SARS-CoV-2 infection MESH:C000657245
1112 1621-1641 Disease denotes SARS-CoV-2 infection MESH:C000657245
1113 1871-1892 Disease denotes inflammatory diseases MESH:D007249

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T42 396-411 Phenotype denotes cytokine storms http://purl.obolibrary.org/obo/HP_0033041
T43 661-675 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T44 796-803 Phenotype denotes Obesity http://purl.obolibrary.org/obo/HP_0001513
T45 1486-1500 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T344 0-10 Sentence denotes SARS-CoV-2
T345 11-297 Sentence denotes Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) refers to a coronavirus strain that causes 2019 coronavirus disease (COVID-19), a respiratory disease that is the cause of the COVID-19 pandemic (Coronaviridae Study Group of the International Committee on Taxonomy of, 2020).
T346 298-426 Sentence denotes SARS-CoV-2 is an RNA virus that infects the lungs and causes deaths through complications such as cytokine storms (Goldin et al.
T347 427-433 Sentence denotes 2020).
T348 434-612 Sentence denotes The anti-inflammatory action of mesenchymal stem cells is well known, and it is believed that these mesenchymal stem cells exhibit anti-inflammatory action through PGE2 and LXA4.
T349 613-795 Sentence denotes These lipids mediators alleviate the SARS-CoV-2 cytokine storm, while arachidonic acid, dihomo-gamma-linolenic acid, and gamma-linolenic acid inactivate enveloped viruses (Das 2020).
T350 796-930 Sentence denotes Obesity is a risk factor for SARS-CoV-2 infection, and a BMI of 30 kg/m2 increases the risk of infection by 61% (Bello-Chavolla et al.
T351 931-937 Sentence denotes 2020).
T352 938-1086 Sentence denotes This is likely due to a deficiency of SPMs in obese patients, and this deficiency promotes adverse reactions during SARS-CoV-2 infection (Pal et al.
T353 1087-1093 Sentence denotes 2020).
T354 1094-1219 Sentence denotes LXA4, Elovanoid-N32 or RvD6 isomers reduced expression of angiotensin-converting enzyme 2 (ACE2), but NDP1 did not reduce it.
T355 1220-1390 Sentence denotes These lipids mediators also counteract the binding of the receptor-binding domain (RBD) of SARS-CoV-2 spike (S) protein to the injured cornea (Figs. 3 and 4) (Pham et al.
T356 1391-1397 Sentence denotes 2020).
T357 1398-1523 Sentence denotes Elovanoid-N32 or RvD6 isomers also attenuated the expression of cytokines involved in a cytokine storm and hyperinflammation.
T358 1524-1754 Sentence denotes Based on previous study results that have demonstrated SPMs as potential therapeutic targets for SARS-CoV-2 infection, studies and review on the use of fish oil, an SPMs precursor, as an adjuvant are in progress. (Torrinhas et al.
T359 1755-1774 Sentence denotes 2020; Rogero et al.
T360 1775-1781 Sentence denotes 2020).
T361 1782-2054 Sentence denotes SPMs and soluble epoxide hydrolase inhibitors are currently in clinical trials for other inflammatory diseases and can be quickly converted and used for SARS-CoV-2 management through the removal of cellular debris and inhibition of inflammatory cytokines (Panigrahy et al.
T362 2055-2061 Sentence denotes 2020).