PMC:7781431 / 30128-31334
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
877 | 655-660 | Gene | denotes | COX-2 | Gene:5743 |
878 | 1004-1008 | Gene | denotes | FPR2 | Gene:2358 |
879 | 1009-1012 | Gene | denotes | ALX | Gene:84941 |
880 | 1017-1022 | Gene | denotes | GPR32 | Gene:2854 |
881 | 0-27 | Species | denotes | Respiratory syncytial virus | Tax:12814 |
882 | 49-54 | Species | denotes | human | Tax:9606 |
883 | 86-90 | Species | denotes | HRSV | Tax:11250 |
884 | 96-118 | Species | denotes | human orthopneumovirus | Tax:11250 |
885 | 55-66 | Species | denotes | respiratory | Tax:12814 |
886 | 933-944 | Species | denotes | respiratory | Tax:12814 |
887 | 29-32 | Species | denotes | RSV | Tax:12814 |
888 | 384-387 | Species | denotes | RSV | Tax:12814 |
889 | 643-646 | Species | denotes | RSV | Tax:12814 |
890 | 961-964 | Species | denotes | RSV | Tax:12814 |
891 | 1149-1152 | Species | denotes | RSV | Tax:12814 |
892 | 867-898 | Chemical | denotes | polyinosinic-polycytidylic acid | MESH:D011070 |
893 | 1096-1101 | Chemical | denotes | lipid | MESH:D008055 |
894 | 143-165 | Disease | denotes | respiratory infections | MESH:D012141 |
895 | 175-183 | Disease | denotes | infected | MESH:D007239 |
896 | 287-315 | Disease | denotes | respiratory tract infections | MESH:D012141 |
897 | 388-397 | Disease | denotes | infection | MESH:D007239 |
898 | 409-422 | Disease | denotes | bronchiolitis | MESH:D001988 |
899 | 1186-1195 | Disease | denotes | infection | MESH:D007239 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T27 | 143-165 | Phenotype | denotes | respiratory infections | http://purl.obolibrary.org/obo/HP_0011947 |
T28 | 281-315 | Phenotype | denotes | lower respiratory tract infections | http://purl.obolibrary.org/obo/HP_0002783 |
T29 | 409-422 | Phenotype | denotes | bronchiolitis | http://purl.obolibrary.org/obo/HP_0011950 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T300 | 0-253 | Sentence | denotes | Respiratory syncytial virus (RSV), also known as human respiratory cell fusion virus (HRSV) and human orthopneumovirus, is a virus that causes respiratory infections in which infected mucosal cells fuse to form a syncytium (Schweitzer and Justice 2020). |
T301 | 254-383 | Sentence | denotes | It is the leading cause of lower respiratory tract infections and hospital visits in infancy and childhood (Read and Bosco 2020). |
T302 | 384-554 | Sentence | denotes | RSV infection results in bronchiolitis, which is classically caused by activated macrophages and eventually resolved by alternatively activated macrophages (Shirey et al. |
T303 | 555-561 | Sentence | denotes | 2010). |
T304 | 562-735 | Sentence | denotes | The promotion of these two alternative macrophage fates appears to be related to RSV-induced COX-2 and LXA4 and RvE1-mediated protective measures (Fig. 4) (Richardson et al. |
T305 | 736-755 | Sentence | denotes | 2005; Shirey et al. |
T306 | 756-762 | Sentence | denotes | 2014). |
T307 | 763-1036 | Sentence | denotes | Also, although it does not directly act on the virus, RvD1 inhibits inflammatory signal transduction by polyinosinic-polycytidylic acid, an analogue of RNAs derived from respiratory viruses such as RSV, and the action of RvD1 is mediated by FPR2/ALX and GPR32 (Hsiao et al. |
T308 | 1037-1043 | Sentence | denotes | 2014). |
T309 | 1044-1206 | Sentence | denotes | These reports suggest the critical role of SPMs and lipid mediator class shift in the host’s response to RSV in the initial control and final infection clearance. |